diazoxide has been researched along with Injuries, Spinal Cord in 4 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Experimental groups were sham (no pretreatment or ischemia, n = 10), spinal cord injury control (pretreatment with normal saline, n = 27), Nicorandil 1." | 4.31 | Direct and indirect activation of the adenosine triphosphate-sensitive potassium channel to induce spinal cord ischemic metabolic tolerance. ( Aftab, M; Cheng, L; Cleveland, JC; Fullerton, DA; Ghincea, CV; Ikeno, Y; Meng, X; Reece, TB; Roda, GF; Weyant, MJ, 2023) |
| "Western blot analysis demonstrated that optimal βcR up-regulation occurred at 36 hours after DZ administration, and the optimal DZ dosage for βcR induction was 20 mg/kg." | 1.48 | Optimized induction of beta common receptor enhances the neuroprotective function of erythropoietin in spinal cord ischemic injury. ( Aftab, M; Cleveland, JC; Eldeiry, M; Fullerton, DA; Mares, J; Meng, X; Reece, TB; Ryan, TJ; Weyant, MJ; Yamanaka, K, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikeno, Y | 1 |
| Ghincea, CV | 1 |
| Roda, GF | 1 |
| Cheng, L | 1 |
| Aftab, M | 2 |
| Meng, X | 2 |
| Weyant, MJ | 2 |
| Cleveland, JC | 2 |
| Fullerton, DA | 2 |
| Reece, TB | 2 |
| Yamanaka, K | 1 |
| Eldeiry, M | 1 |
| Mares, J | 1 |
| Ryan, TJ | 1 |
| Woo, SK | 1 |
| Kwon, MS | 1 |
| Ivanov, A | 1 |
| Gerzanich, V | 1 |
| Simard, JM | 1 |
| Erickson, RP | 1 |
1 review available for diazoxide and Injuries, Spinal Cord
| Article | Year |
|---|---|
Autonomic hyperreflexia: pathophysiology and medical management.
Topics: Anesthesia, Spinal; Catecholamines; Diazoxide; Humans; Hydralazine; Neurotransmitter Agents; Nitropr | 1980 |
3 other studies available for diazoxide and Injuries, Spinal Cord
| Article | Year |
|---|---|
Direct and indirect activation of the adenosine triphosphate-sensitive potassium channel to induce spinal cord ischemic metabolic tolerance.
Topics: Adenosine Triphosphate; Animals; Diazoxide; Ischemia; Male; Mice; Mice, Inbred C57BL; Nicorandil; Ni | 2023 |
Optimized induction of beta common receptor enhances the neuroprotective function of erythropoietin in spinal cord ischemic injury.
Topics: Animals; Diazoxide; Erythropoietin; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Receptor | 2018 |
The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel.
Topics: Animals; ATP-Binding Cassette Transporters; Cell Membrane; Chlorocebus aethiops; COS Cells; Diazoxid | 2013 |