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diazoxide and Infant, Small for Gestational Age

diazoxide has been researched along with Infant, Small for Gestational Age in 9 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Infant, Small for Gestational Age: An infant having a birth weight lower than expected for its gestational age.

Research Excerpts

ExcerptRelevanceReference
"Diazoxide is commonly used in the treatment of neonatal hyperinsulinism."7.74Development of pulmonary hypertension in an infant treated with diazoxide. ( Caldwell, RL; Eugster, EA; Hoover, WC; Nebesio, TD; Nitu, ME, 2007)
"Diazoxide is commonly used in the treatment of neonatal hyperinsulinism."3.74Development of pulmonary hypertension in an infant treated with diazoxide. ( Caldwell, RL; Eugster, EA; Hoover, WC; Nebesio, TD; Nitu, ME, 2007)
"02) were significantly lower in the diazoxide group, with no adverse effects attributed to the drug."2.87Randomised controlled trial of diazoxide for small for gestational age neonates with hyperinsulinaemic hypoglycaemia provided early hypoglycaemic control without adverse effects. ( Attri, SV; Balachandran, B; Mukhopadhyay, K; Sachdeva, N; Walia, R, 2018)
"Current concepts in the conduct of preterm labor and management of delivery of the premature infant are reviewed."2.36Contemporary management and conduct of preterm labor and delivery: a review. ( Guilliams, S; Held, B, 1979)
"Diazoxide was initiated at 3 mg/kg/day at a median age of 10 days."1.72Safety and efficacy of low-dose diazoxide in small-for-gestational-age infants with hyperinsulinaemic hypoglycaemia. ( Chandran, S; Mei Chien, C; R, PR; Rajadurai, VS; Saffari, SE; Yap, F, 2022)
"Hyperinsulinism was diagnosed as hypoglycemia concomitant with high serum insulin in babies requiring >6 mg/kg/min intravenous glucose and THI as hyperinsulinism without maternal diabetes or genetic disorders."1.42Fetal Erythroblastosis May Be an Indicator of Neonatal Transient Hyperinsulinism. ( Hata, D; Iki, Y; Katayama, T; Kawai, M; Mizumoto, H; Yamashita, S, 2015)
"Treatment with diazoxide and chlorothiazide was effective."1.31The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy. ( Barbetti, F; Brusgaard, K; Buettger, C; Christesen, HB; Cuesta-Munoz, A; Hansen, T; Jacobsen, BB; Magnuson, MA; Massa, O; Matschinsky, FM; Odili, S; Shiota, C, 2002)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Chandran, S2
R, PR1
Mei Chien, C1
Saffari, SE1
Rajadurai, VS2
Yap, F1
Balachandran, B1
Mukhopadhyay, K1
Sachdeva, N1
Walia, R1
Attri, SV1
Chong, JH1
Agarwal, P1
Blanco, M1
Khan, O1
Stanley, K1
Hageman, JR1
Greeley, SA1
Mizumoto, H1
Iki, Y1
Yamashita, S1
Kawai, M1
Katayama, T1
Hata, D1
Arya, VB1
Flanagan, SE1
Kumaran, A1
Shield, JP1
Ellard, S1
Hussain, K1
Kapoor, RR1
Nebesio, TD1
Hoover, WC1
Caldwell, RL1
Nitu, ME1
Eugster, EA1
Christesen, HB1
Jacobsen, BB1
Odili, S1
Buettger, C1
Cuesta-Munoz, A1
Hansen, T1
Brusgaard, K1
Massa, O1
Magnuson, MA1
Shiota, C1
Matschinsky, FM1
Barbetti, F1
Guilliams, S1
Held, B1

Reviews

1 review available for diazoxide and Infant, Small for Gestational Age

ArticleYear
Contemporary management and conduct of preterm labor and delivery: a review.
    Obstetrical & gynecological survey, 1979, Volume: 34, Issue:3

    Topics: Adrenal Cortex Hormones; Bed Rest; Diazoxide; Female; Fetal Distress; Humans; Infant, Newborn; Infan

1979

Trials

1 trial available for diazoxide and Infant, Small for Gestational Age

ArticleYear
Randomised controlled trial of diazoxide for small for gestational age neonates with hyperinsulinaemic hypoglycaemia provided early hypoglycaemic control without adverse effects.
    Acta paediatrica (Oslo, Norway : 1992), 2018, Volume: 107, Issue:6

    Topics: Congenital Hyperinsulinism; Diazoxide; Female; Humans; Infant, Newborn; Infant, Small for Gestationa

2018

Other Studies

7 other studies available for diazoxide and Infant, Small for Gestational Age

ArticleYear
Safety and efficacy of low-dose diazoxide in small-for-gestational-age infants with hyperinsulinaemic hypoglycaemia.
    Archives of disease in childhood. Fetal and neonatal edition, 2022, Volume: 107, Issue:4

    Topics: Child; Congenital Hyperinsulinism; Diazoxide; Female; Gestational Age; Humans; Infant; Infant, Newbo

2022
Delayed presentation of prolonged hyperinsulinaemic hypoglycaemia in a preterm small-for-gestational age neonate.
    BMJ case reports, 2013, Dec-18, Volume: 2013

    Topics: Blood Glucose; Diazoxide; Female; Humans; Hyperinsulinism; Hypoglycemia; Infant, Newborn; Infant, Sm

2013
Hyperinsulinism in a neonate.
    Pediatric annals, 2014, Volume: 43, Issue:3

    Topics: Blood Glucose; Diagnosis, Differential; Diazoxide; Humans; Hyperinsulinism; Infant, Newborn; Infant,

2014
Fetal Erythroblastosis May Be an Indicator of Neonatal Transient Hyperinsulinism.
    Neonatology, 2015, Volume: 108, Issue:2

    Topics: Apgar Score; Birth Weight; Diazoxide; Erythroblastosis, Fetal; Erythrocyte Count; Female; Gestationa

2015
Clinical and molecular characterisation of hyperinsulinaemic hypoglycaemia in infants born small-for-gestational age.
    Archives of disease in childhood. Fetal and neonatal edition, 2013, Volume: 98, Issue:4

    Topics: Antihypertensive Agents; ATP-Binding Cassette Transporters; Blood Glucose; Diazoxide; Gestational Ag

2013
Development of pulmonary hypertension in an infant treated with diazoxide.
    Journal of pediatric endocrinology & metabolism : JPEM, 2007, Volume: 20, Issue:8

    Topics: Diazoxide; Female; Humans; Hyperinsulinism; Hypertension, Pulmonary; Hypoglycemia; Hypoglycemic Agen

2007
The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy.
    Diabetes, 2002, Volume: 51, Issue:4

    Topics: Adolescent; Allosteric Regulation; Diabetes Mellitus; Diazoxide; Enzyme Activation; Glucokinase; Glu

2002