diazoxide has been researched along with Hypokalemia in 5 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five patients suffering from familial periodic paralysis with hypokalemia (FPP) were exposed to standard paralysis induction trials which elicited total paralyysis and hypokalemia." | 6.64 | Trial of the prophylactic effect of diazoxide in the treatment of familial periodic hypokalemia. ( Johnsen, T, 1977) |
| "Five patients suffering from familial periodic paralysis with hypokalemia (FPP) were exposed to standard paralysis induction trials which elicited total paralyysis and hypokalemia." | 2.64 | Trial of the prophylactic effect of diazoxide in the treatment of familial periodic hypokalemia. ( Johnsen, T, 1977) |
| "In five patients with islet cell tumors and fasting hypoglycemia, basal proinsulin-like component ranged from 26 to 79% of the total immunoreactive insulin." | 1.25 | Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors. ( Gorden, P; Roth, J; Sherman, B, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sodi, R | 1 |
| Davison, AS | 1 |
| Holmes, E | 1 |
| Hine, TJ | 1 |
| Roberts, NB | 1 |
| Johnsen, T | 1 |
| Gorden, P | 1 |
| Sherman, B | 1 |
| Roth, J | 1 |
| Marcus, DF | 1 |
| Wales, JK | 1 |
| Viktoria, JK | 1 |
| Wolff, FW | 1 |
| Seltzer, HS | 1 |
| Allen, EW | 1 |
1 trial available for diazoxide and Hypokalemia
| Article | Year |
|---|---|
Trial of the prophylactic effect of diazoxide in the treatment of familial periodic hypokalemia.
Topics: Acute Disease; Blood Glucose; Clinical Trials as Topic; Diazoxide; Drug Evaluation; Drug Resistance; | 1977 |
4 other studies available for diazoxide and Hypokalemia
| Article | Year |
|---|---|
The phenomenon of seasonal pseudohypokalemia: effects of ambient temperature, plasma glucose and role for sodium-potassium-exchanging-ATPase.
Topics: Blood Glucose; Diazoxide; Enzyme Activation; Humans; Hypokalemia; Membrane Transport Modulators; Pin | 2009 |
Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Animals; Child; Chromatography, Gel; Cricetinae; | 1971 |
A comparative study of various hyperglycemic agents in potassium deficient rats.
Topics: Alkalosis; Animals; Blood Glucose; Diazoxide; Epinephrine; Glucagon; Glycogen; Heptoses; Hydrocortis | 1968 |
Hyperglycemia and inhibition of insulin secretion during administration of diazoxide and trichlormethiazide in man.
Topics: Blood Glucose; Diabetes Mellitus; Diazoxide; Drug Synergism; Glucose Tolerance Test; Humans; Hypergl | 1969 |