diazoxide has been researched along with Hypertrichosis in 22 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Hypertrichosis: Excessive hair growth at inappropriate locations, such as on the extremities, the head, and the back. It is caused by genetic or acquired factors, and is an androgen-independent process. This concept does not include HIRSUTISM which is an androgen-dependent excess hair growth in WOMEN and CHILDREN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazoxide is the first-line drug for treating hyperinsulinism and the only pharmacological agent approved for hyperinsulinism by the Federal Drug Administration." | 9.12 | Efficacy and safety of diazoxide for treating hyperinsulinemic hypoglycemia: A systematic review and meta-analysis. ( Chen, X; Feng, L; Qin, Y; Yang, L; Yao, H, 2021) |
| "The efficacy and side effects of two potent vasodilatators, namely diazoxide and minoxidil given orally, were compared in 11 patients who had hypertension refractory to conventional drug treatment." | 7.66 | [Comparison of oral diazoxide and minoxidil in refractory hypertension]. ( Glück, Z; Grimm, M; Keusch, G; Meier, A; Minder, I; Reubi, FC; Weidmann, P, 1980) |
| "Two cases of hypertrichosis due to diazoxide are described." | 7.65 | Hypertrichosis due to diazoxide. ( Burton, JL; Caldwell, IW; Schutt, WH, 1975) |
| "Since 1969 leucine sensitive hypoglycemia has been diagnosed in 4 infants." | 7.65 | [Leucine sensitive hypoglycemia. Follow-up studies under treatment with diazoxide (author's transl)]. ( Lücking, T, 1976) |
| "Diazoxide is the first-line drug for treating hyperinsulinism and the only pharmacological agent approved for hyperinsulinism by the Federal Drug Administration." | 5.12 | Efficacy and safety of diazoxide for treating hyperinsulinemic hypoglycemia: A systematic review and meta-analysis. ( Chen, X; Feng, L; Qin, Y; Yang, L; Yao, H, 2021) |
| "The efficacy and side effects of two potent vasodilatators, namely diazoxide and minoxidil given orally, were compared in 11 patients who had hypertension refractory to conventional drug treatment." | 3.66 | [Comparison of oral diazoxide and minoxidil in refractory hypertension]. ( Glück, Z; Grimm, M; Keusch, G; Meier, A; Minder, I; Reubi, FC; Weidmann, P, 1980) |
| "Two cases of hypertrichosis due to diazoxide are described." | 3.65 | Hypertrichosis due to diazoxide. ( Burton, JL; Caldwell, IW; Schutt, WH, 1975) |
| "Since 1969 leucine sensitive hypoglycemia has been diagnosed in 4 infants." | 3.65 | [Leucine sensitive hypoglycemia. Follow-up studies under treatment with diazoxide (author's transl)]. ( Lücking, T, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (77.27) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X | 1 |
| Feng, L | 1 |
| Yao, H | 1 |
| Yang, L | 1 |
| Qin, Y | 1 |
| Shah, P | 1 |
| Rahman, SA | 1 |
| McElroy, S | 1 |
| Gilbert, C | 1 |
| Morgan, K | 1 |
| Hinchey, L | 1 |
| Senniappan, S | 1 |
| Levy, H | 1 |
| Amin, R | 1 |
| Hussain, K | 1 |
| Newfield, RS | 1 |
| Henn, MC | 1 |
| Janjua, MB | 1 |
| Zhang, H | 1 |
| Kanter, EM | 1 |
| Makepeace, CM | 1 |
| Schuessler, RB | 1 |
| Nichols, CG | 1 |
| Lawton, JS | 1 |
| Salido, R | 1 |
| Gómez-García, FJ | 1 |
| Garnacho-Saucedo, G | 1 |
| Galán-Gutiérrez, M | 1 |
| Parker, LN | 1 |
| Lifrak, ET | 1 |
| Odell, WD | 1 |
| Pérez Mijares, R | 1 |
| Elosegui, A | 1 |
| Praga, M | 1 |
| Vidaur, F | 1 |
| Izaguirre, A | 1 |
| Argoitia, A | 1 |
| López de Novales, E | 1 |
| Meier, A | 1 |
| Weidmann, P | 1 |
| Glück, Z | 1 |
| Keusch, G | 1 |
| Grimm, M | 1 |
| Minder, I | 1 |
| Reubi, FC | 1 |
| Burton, JL | 1 |
| Schutt, WH | 1 |
| Caldwell, IW | 1 |
| Lücking, T | 2 |
| Rousseau, C | 1 |
| Willocx, D | 1 |
| Bourlond, A | 1 |
| Buts, JP | 1 |
| Maes, M | 1 |
| Lopez, A | 1 |
| Prigent, F | 1 |
| Gantzer, A | 1 |
| Romain, O | 1 |
| Massonaud, M | 1 |
| Aufrant, C | 1 |
| Bompard, Y | 1 |
| Leng, JJ | 1 |
| Greenblatt, RB | 1 |
| Wegienka, LC | 1 |
| Simpson, RG | 1 |
| Karam, JH | 1 |
| Forsham, PH | 1 |
| Milner, RD | 1 |
| Chouksey, SK | 1 |
| Menter, MA | 1 |
| Victorin, LH | 1 |
| Thorell, JI | 1 |
| McLaine, PN | 1 |
| Drummond, KN | 1 |
| Green, OC | 1 |
| Berger, S | 1 |
| Koblenzer, PJ | 2 |
| Baker, L | 2 |
1 review available for diazoxide and Hypertrichosis
| Article | Year |
|---|---|
Efficacy and safety of diazoxide for treating hyperinsulinemic hypoglycemia: A systematic review and meta-analysis.
Topics: Antihypertensive Agents; Diazoxide; Humans; Hyperinsulinism; Hypertrichosis; Hypoglycemia; Treatment | 2021 |
21 other studies available for diazoxide and Hypertrichosis
| Article | Year |
|---|---|
Use of Long-Acting Somatostatin Analogue (Lanreotide) in an Adolescent with Diazoxide-Responsive Congenital Hyperinsulinism and Its Psychological Impact.
Topics: Adolescent; Blood Glucose; Congenital Hyperinsulinism; Diazoxide; Diuretics; Female; Humans; Hypertr | 2015 |
Topical sulfonylurea as a novel therapy for hypertrichosis secondary to diazoxide, and potentially for other conditions with excess hair growth.
Topics: Administration, Topical; Cardiomegaly; Diazoxide; Hair; Humans; Hypertrichosis; Mutation; Osteochond | 2015 |
Increased tolerance to stress in cardiac expressed gain-of-function of adenosine triphosphate-sensitive potassium channel subunit Kir6.1.
Topics: Animals; Cardiomegaly; Cell Size; Diazoxide; Genetic Markers; Hypertrichosis; KATP Channels; Mice; M | 2016 |
Acquired generalized hypertrichosis due to diazoxide.
Topics: Child; Diazoxide; Humans; Hypertrichosis; Male | 2013 |
Lack of a gonadal or adrenal androgenic mechanism for the hypertrichosis produced by diazoxide, phenytoin and minoxidil.
Topics: Adrenal Glands; Androgens; Animals; Diazoxide; Hypertrichosis; In Vitro Techniques; Male; Minoxidil; | 1982 |
[Hypertrichosis following prolonged use of i.v. diazoxide. Apropos of a case].
Topics: Adolescent; Diazoxide; Female; Humans; Hypertension, Renal; Hypertrichosis; Infusions, Parenteral; K | 1981 |
[Comparison of oral diazoxide and minoxidil in refractory hypertension].
Topics: Blood Glucose; Blood Pressure; Body Weight; Diazoxide; Diuretics; Drug Therapy, Combination; Electro | 1980 |
Hypertrichosis due to diazoxide.
Topics: Aged; Child; Diazoxide; Humans; Hypertension; Hypertrichosis; Hypoglycemia; Male | 1975 |
[Leucine sensitive hypoglycemia. Follow-up studies under treatment with diazoxide (author's transl)].
Topics: Blood Glucose; Diazoxide; Dietary Proteins; Drug Hypersensitivity; Epilepsy; Female; Humans; Hypertr | 1976 |
Hypertrichosis induced by diazoxide in idiopathic hypoglycemia of infancy.
Topics: Diazoxide; Female; Humans; Hypertrichosis; Hypoglycemia; Infant, Newborn | 1989 |
[Acquired diffuse hypertrichosis during treatment with diazoxide in a newborn infant].
Topics: Diazoxide; Humans; Hypertrichosis; Hypoglycemia; Infant, Newborn; Male | 1988 |
Hirsutism in adolescent girls.
Topics: Adolescent; Adrenocortical Hyperfunction; Cobalt; Cortisone; Cushing Syndrome; Dexamethasone; Diazox | 1972 |
Clinical experience with diazoxide.
Topics: Adenoma, Islet Cell; Adrenal Glands; Adult; Aged; Benzothiadiazines; Blood Glucose; Diabetes Mellitu | 1968 |
Effects of fetal exposure to diazoxide in man.
Topics: Abnormalities, Drug-Induced; Adult; Age Determination by Skeleton; Alopecia; Amniotic Fluid; Blood G | 1972 |
Hypertrichosis lanuginosa and a lichenoid eruption due to diazoxide therapy.
Topics: Adult; Biopsy; Creatinine; Diazoxide; Female; Humans; Hypertension; Hypertrichosis; Lichen Planus; P | 1973 |
Plasma insulin and blood glucose during long-term treatment with diazoxide for infant hypoglycemia.
Topics: Acidosis; Blood Glucose; Child, Preschool; Diazoxide; Follow-Up Studies; Glucose; Glucose Tolerance | 1974 |
[Diazoxide in the therapy of leucin sensitive hypoglycemia].
Topics: Carbohydrate Metabolism, Inborn Errors; Diazoxide; Humans; Hyperinsulinism; Hypertrichosis; Hypoglyc | 1971 |
Intravenous diazoxide for severe hypertension in childhood.
Topics: Adolescent; Blood Pressure; Child; Child, Preschool; Diazoxide; Female; Glomerulonephritis; Humans; | 1971 |
The clinical use of diazoxide in leucine-sensitive hypoglycemia.
Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Diazoxide; Female; Humans; Hyperglycemia; Hy | 1968 |
Hypertrichosis lanuginosa associated with diazoxide therapy in prepubertal children: a clinicopathologic study.
Topics: Androgens; Child, Preschool; Diazoxide; Female; Hair; Humans; Hypertrichosis; Hypoglycemia; Infant; | 1968 |
Hypertichosis lanuginosa acquisita.
Topics: Diazoxide; Humans; Hypertrichosis; Hypoglycemia; Infant; Leucine; Male; Pancreatectomy; Seizures | 1969 |