diazoxide has been researched along with Hypertension, Renal in 44 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazoxide was originally approved as an anti-hypertensive medication, but also is known to bind ATP-sensitive K channels in the beta cells of the pancreas, ultimately leading to inhibition of insulin release." | 5.56 | The use of diazoxide in the management of spontaneous hypoglycemia in patients with ESRD. ( Kristan, M; Lamos, EM; Malek, R; Mesmar, B; Munir, KM; Satyarengga, M, 2020) |
| " diazoxide in a dosage of 5 mg/kg b." | 5.25 | Diazoxide in the management of severe hypertension. ( Kolendorf, K; Moller, BB, 1975) |
| "The effect on cerebral blood flow of acute diazoxide-induced hypotension was studied in rats with renal and spontaneous hypertension." | 3.66 | Effect of diazoxide-induced hypotension on cerebral blood flow in hypertensive rats. ( Barry, DI; Bolwig, TG; Braendstrup, O; Graham, DI; Strandgaard, S; Svendsen, UG, 1983) |
| "Diazoxide was originally approved as an anti-hypertensive medication, but also is known to bind ATP-sensitive K channels in the beta cells of the pancreas, ultimately leading to inhibition of insulin release." | 1.56 | The use of diazoxide in the management of spontaneous hypoglycemia in patients with ESRD. ( Kristan, M; Lamos, EM; Malek, R; Mesmar, B; Munir, KM; Satyarengga, M, 2020) |
| "Propranolol pretreatment of HT rats decreases the hypotensive effect induced by the three vasodilators." | 1.26 | Cardiovascular effects of dihydralazine diazoxide and minoxidil alone or associated with propranolol in renal hypertensive rats. ( Cohen, Y; Lindenbaum, A; Provost, Y; Wepierre, J, 1981) |
| "Renal disease and hypertension is a continuing challenge to the nephrologist." | 1.26 | The kidney and antihypertensive therapy. ( Bailey, RR, 1976) |
| "Cause of renal disease are chronic renal failure in three, acute renal failure in three, hemolytic uremic syndrome in two, acute post streptococcal glomerulonephritis in one, and renal arterial stenosis in a further patient." | 1.26 | [Hypertensive emergencies in children with renal hypertension (author's transl)]. ( Bachmann, HJ; Olbing, H; Pistor, K, 1979) |
| " diazoxide in a dosage of 5 mg/kg b." | 1.25 | Diazoxide in the management of severe hypertension. ( Kolendorf, K; Moller, BB, 1975) |
| "Treatment with diazoxide could be continued in four of these." | 1.25 | Development of extrapyramidal symptoms in hypertensive patients treated with diazoxide. ( Neary, D; Pohl, JE; Thurston, H, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (97.73) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.27) | 2.80 |
| Authors | Studies |
|---|---|
| Mesmar, B | 1 |
| Kristan, M | 1 |
| Satyarengga, M | 1 |
| Lamos, EM | 1 |
| Malek, R | 1 |
| Munir, KM | 1 |
| BRUSCA, A | 1 |
| WOELFER, HJ | 1 |
| SCHNEIDER, KW | 1 |
| HOCHREIN, H | 1 |
| Barry, DI | 1 |
| Strandgaard, S | 1 |
| Graham, DI | 1 |
| Braendstrup, O | 1 |
| Svendsen, UG | 1 |
| Bolwig, TG | 1 |
| Provost, Y | 1 |
| Lindenbaum, A | 1 |
| Cohen, Y | 1 |
| Wepierre, J | 1 |
| Pérez Mijares, R | 1 |
| Elosegui, A | 1 |
| Praga, M | 1 |
| Vidaur, F | 1 |
| Izaguirre, A | 1 |
| Argoitia, A | 1 |
| López de Novales, E | 1 |
| Bailey, RR | 1 |
| Derkx, FH | 1 |
| Verhoeven, RP | 1 |
| Wenting, GJ | 1 |
| Man in 't Veld, AJ | 1 |
| Schalekamp, MA | 1 |
| Bedani, PL | 1 |
| Farinelli, A | 1 |
| Adelman, RD | 1 |
| Merten, D | 1 |
| Vogel, J | 1 |
| Goetzman, BW | 1 |
| Wennberg, RP | 1 |
| Cecchettin, M | 1 |
| Maiorca, R | 1 |
| Bachmann, HJ | 1 |
| Olbing, H | 1 |
| Pistor, K | 1 |
| White, RP | 1 |
| Haas, Th | 1 |
| Denkl, P | 1 |
| Fleischmann, LE | 1 |
| Mantero, F | 1 |
| Perini, A | 1 |
| Armanini, D | 1 |
| Gion, M | 1 |
| Opocher, G | 1 |
| Boscaro, M | 1 |
| Stokes, GS | 1 |
| Weber, MA | 1 |
| Gain, J | 1 |
| Scott, AJ | 1 |
| Roberts, BA | 1 |
| Sheil, AG | 1 |
| Stockigt, JR | 1 |
| Higgs, EJ | 1 |
| Sacharias, N | 1 |
| Forsythe, WE | 1 |
| Persky, L | 1 |
| Rowe, WS | 1 |
| Diekmann, L | 1 |
| Moller, BB | 1 |
| Kolendorf, K | 1 |
| Woods, JR | 1 |
| Brinkman, CR | 1 |
| Kincaid-Smith, P | 2 |
| Schmitt, H | 1 |
| Laubie, M | 1 |
| Meurer, KA | 1 |
| Ganten, D | 1 |
| Kaufmann, W | 1 |
| Finnerty, FA | 1 |
| Cangiano, JL | 1 |
| Ramírez González, R | 1 |
| Ramírez-Muxó, O | 1 |
| Pijem, E | 1 |
| Waddell, E | 1 |
| Thurston, H | 2 |
| Pohl, JE | 2 |
| Swales, JD | 1 |
| Neary, D | 1 |
| Nellen, M | 1 |
| Klaus, D | 4 |
| Bourke, E | 1 |
| Gatenby, PB | 1 |
| Guedon, J | 1 |
| Buisson, C | 1 |
| Bursaux, E | 1 |
| Overbeck, HW | 1 |
| McLaine, PN | 1 |
| Drummond, KN | 1 |
| Mathew, TH | 1 |
| Just, H | 1 |
| Stein, U | 1 |
| Schmelzle, R | 1 |
| Simsch, A | 1 |
| Trübestein, G | 1 |
| Sheps, SG | 1 |
| Richet, G | 1 |
| Ducrot, H | 1 |
| Hamburger, J | 1 |
| Legrain, M | 1 |
| Maxwell, M | 1 |
| Péquignot, MH | 1 |
| Küchel, O | 1 |
1 review available for diazoxide and Hypertension, Renal
| Article | Year |
|---|---|
[THERAPY OF ESSENTIAL HYPERTENSION].
Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Coronary Disease; Diazoxide; Diet; Dihydr | 1963 |
3 trials available for diazoxide and Hypertension, Renal
| Article | Year |
|---|---|
[Diazoxide in arterial hypertensive emergencies].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diazoxide; Emergencies; Fe | 1979 |
Diazoxide in the treatment of hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Child, Preschool; Clinical Tria | 1970 |
The significance of plasma renin determinations for differential diagnosis of hypertensiony.
Topics: Chronic Disease; Clinical Trials as Topic; Diagnosis, Differential; Diazoxide; Diet, Sodium-Restrict | 1970 |
40 other studies available for diazoxide and Hypertension, Renal
| Article | Year |
|---|---|
The use of diazoxide in the management of spontaneous hypoglycemia in patients with ESRD.
Topics: Aged; Diazoxide; Female; Humans; Hypertension, Renal; Hypoglycemia; Kidney Failure, Chronic; Male; M | 2020 |
[CLINICAL AND HEMODYNAMIC STUDIES ON A NEW ANTIHYPERTENSIVE SUBSTANCE FROM THE THIAZIDE GROUP WITHOUT DIURETIC EFFECT].
Topics: Antihypertensive Agents; Benzothiadiazines; Biomedical Research; Blood Circulation; Blood Pressure; | 1963 |
Effect of diazoxide-induced hypotension on cerebral blood flow in hypertensive rats.
Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Diazoxide; Hypertension; Hyper | 1983 |
Cardiovascular effects of dihydralazine diazoxide and minoxidil alone or associated with propranolol in renal hypertensive rats.
Topics: Animals; Antihypertensive Agents; Diazoxide; Dihydralazine; Drug Interactions; Hemodynamics; Hyperte | 1981 |
[Hypertrichosis following prolonged use of i.v. diazoxide. Apropos of a case].
Topics: Adolescent; Diazoxide; Female; Humans; Hypertension, Renal; Hypertrichosis; Infusions, Parenteral; K | 1981 |
The kidney and antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hy | 1976 |
Renal release of active and inactive renin in essential and renovascular hypertension.
Topics: Diazoxide; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Hypertension; Hypertension, Renal; | 1978 |
Nonsurgical management of renovascular hypertension in the neonate.
Topics: Adult; Antihypertensive Agents; Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertension, Ren | 1978 |
[Injectable diazoxide in the treatment of arterial hypertension: its effects on nephroparenchymal hypertension and "accelerated" hypertension].
Topics: Adult; Diazoxide; Drug Evaluation; Humans; Hypertension; Hypertension, Renal; Injections, Intravenou | 1978 |
[Hypertensive emergencies in children with renal hypertension (author's transl)].
Topics: Acute Disease; Acute Kidney Injury; Child; Child, Preschool; Diazoxide; Female; Glomerulonephritis; | 1979 |
Antihypertensive agents in renal disease.
Topics: Antihypertensive Agents; Body Water; Clonidine; Diazoxide; Ethacrynic Acid; Furosemide; Guanethidine | 1977 |
[Therapy of hypertensive crises].
Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine | 1977 |
Management of hypertensive crisis in children.
Topics: Acute Disease; Adolescent; Cerebrovascular Disorders; Child; Child, Preschool; Diazoxide; Humans; Hy | 1977 |
[Effect of diazoxide on blood pressure, PRA and plasma aldosterone in hypertensive patients (author's transl)].
Topics: Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Diazoxide; Humans; Hyperaldosteronism; Hyperte | 1976 |
Diazoxide-induced renin release in diagnosis of remediable renovascular hypertension.
Topics: Adolescent; Adult; Aged; Child; Diazoxide; Female; Humans; Hypertension, Renal; Male; Middle Aged; R | 1976 |
Diazoxide-induced stimulation of renin release in renal vein renin sampling.
Topics: Adult; Diazoxide; Female; Humans; Hypertension, Renal; Renal Veins; Renin; Secretory Rate; Stimulati | 1976 |
A case of renovascular hypertension in a 9-month-old child.
Topics: Age Factors; Diazoxide; Female; Humans; Hydralazine; Hypertension, Renal; Infant; Renal Artery; Rena | 1975 |
Some aspects of the management of hypertension II. Special considerations.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure Determination; Diazoxide; Drug Therapy, Combina | 1975 |
[The acute crisis of blood pressure and its treatment in childhood (authors transl)].
Topics: Acute Disease; Acute Kidney Injury; Administration, Oral; Adolescent; Age Factors; Child; Diazoxide; | 1975 |
Diazoxide in the management of severe hypertension.
Topics: Adult; Aged; Creatinine; Diazoxide; Female; Humans; Hypertension; Hypertension, Malignant; Hypertens | 1975 |
The treatment of gestational hypertension.
Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype | 1975 |
Nephrology Mexico.
Topics: Administration, Oral; Diazoxide; Humans; Hypertension, Renal; Injections, Intravenous | 1973 |
[Actions of diazoxide on the cardiovascular system, on the metabolism of the myocardium and on sympathetic discharges].
Topics: Angiotensin II; Animals; Cardiovascular System; Diazoxide; Dogs; Hemodynamics; Hypertension; Hyperte | 1968 |
[A test for assessing the responsiveness of plasma renin activity].
Topics: Angiotensin II; Biological Assay; Diazoxide; Diet, Sodium-Restricted; Furosemide; Humans; Hypertensi | 1970 |
Aggressive drug therapy in accelerated hypertension.
Topics: Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxide; Ferr | 1974 |
Treatment of drug resistant hypertension in chronic kidney disease.
Topics: Administration, Oral; Adult; Diazoxide; Drug Resistance; Evaluation Studies as Topic; Humans; Hypert | 1972 |
The effect of oral diazoxide on hypertension and sodium excretion in chronic renal failure.
Topics: Blood Glucose; Carbohydrates; Creatinine; Diazoxide; Edema; Glomerulonephritis; Humans; Hypertension | 1973 |
Development of extrapyramidal symptoms in hypertensive patients treated with diazoxide.
Topics: Adult; Aged; Basal Ganglia Diseases; Diazepam; Diazoxide; Female; Humans; Hypertension; Hypertension | 1973 |
Renal artery dysplasia with hypertension in neurofibromatosis.
Topics: Antihypertensive Agents; Blood Pressure; Child; Chlorothiazide; Diazoxide; Electroencephalography; G | 1971 |
[Total peripheral resistance in human arterial hypertension. Hemodynamic effects of diazoxide].
Topics: Adolescent; Adult; Blood Pressure; Body Surface Area; Cardiac Output; Creatinine; Diazoxide; Electro | 1972 |
Hemodynamics of early experimental renal hypertension in dogs. Normal limb blood flow, elevated limb vascular resistance, and decreased venous compliance.
Topics: Animals; Blood Pressure; Blood Volume; Diazoxide; Disease Models, Animal; Dogs; Femoral Vein; Foreli | 1972 |
[Arterial hypertension: etiology, diagnosis, treatment].
Topics: Adrenocortical Hyperfunction; Adult; Arteries; Diazoxide; Humans; Hyperaldosteronism; Hypertension; | 1971 |
Intravenous diazoxide for severe hypertension in childhood.
Topics: Adolescent; Blood Pressure; Child; Child, Preschool; Diazoxide; Female; Glomerulonephritis; Humans; | 1971 |
The use of diazoxide in hypertensive crises with particular reference to the control of hypertension in severe renal failure.
Topics: Acute Kidney Injury; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Diazoxide; Femal | 1971 |
[Effect of diazoxide, a new bllood pressure lowering substance, on the general and pulmonary circulatory system in hypertension].
Topics: Blood Circulation Time; Blood Pressure; Cardiac Output; Cardiovascular System; Diazoxide; Humans; Hy | 1969 |
[Arterial hypertension: etiology, differential diagnosis, and therapy].
Topics: Adrenocortical Hyperfunction; Adult; Arteries; Diazoxide; Humans; Hyperaldosteronism; Hypertension; | 1969 |
[Plasma renin activity after the injection of orthortase and diazoxide in primary and renal hypertension].
Topics: Blood Pressure; Diazoxide; Enzymes; Humans; Hypertension; Hypertension, Renal; Juxtaglomerular Appar | 1970 |
Hypertensive crisis.
Topics: Administration, Oral; Adolescent; Aged; Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertens | 1971 |
[May medical therapy of arterial hypertension by used in patients with renal failure?].
Topics: Antihypertensive Agents; Diazoxide; Drug Tolerance; Guanethidine; Humans; Hydralazine; Hypertension; | 1968 |
[What can endocrine diagnosis contribute to the classification and rational treatment of hypertension?].
Topics: Diazoxide; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Prospective Studies; Renin | 1969 |