Page last updated: 2024-10-25

diazoxide and Hibernation, Myocardial

diazoxide has been researched along with Hibernation, Myocardial in 6 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
del Valle, HF1
Lascano, EC1
Negroni, JA1
Suzuki, M1
Saito, T1
Sato, T1
Tamagawa, M1
Miki, T1
Seino, S1
Nakaya, H1
Duncker, DJ1
Verdouw, PD1
Wang, X1
Wei, M1
Kuukasjärvi, P1
Laurikka, J1
Järvinen, O1
Rinne, T1
Honkonen, EL1
Tarkka, M1
Mizutani, S1
Al-Dadah, AS1
Bloch, JB1
Prasad, SM1
Diodato, MD1
Schuessler, RB1
Damiano, RJ1
Lawton, JS1
Takano, H1
Tang, XL1
Bolli, R1

Trials

1 trial available for diazoxide and Hibernation, Myocardial

ArticleYear
Novel pharmacological preconditioning with diazoxide attenuates myocardial stunning in coronary artery bypass grafting.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2003, Volume: 24, Issue:6

    Topics: Aged; Biomarkers; Coronary Artery Bypass; Creatine Kinase; Creatine Kinase, MB Form; Diazoxide; Fema

2003

Other Studies

5 other studies available for diazoxide and Hibernation, Myocardial

ArticleYear
Ischemic preconditioning protection against stunning in conscious diabetic sheep: role of glucose, insulin, sarcolemmal and mitochondrial KATP channels.
    Cardiovascular research, 2002, Aug-15, Volume: 55, Issue:3

    Topics: Action Potentials; Analysis of Variance; Animals; Decanoic Acids; Diabetes Mellitus, Experimental; D

2002
Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice.
    Circulation, 2003, Feb-11, Volume: 107, Issue:5

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzamides; Cardiotonic Agents; Diazoxide; In Vi

2003
Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice.
    Circulation, 2003, Aug-12, Volume: 108, Issue:6

    Topics: Adenosine Triphosphate; Animals; Cardiotonic Agents; Diazoxide; Disease Models, Animal; Dose-Respons

2003
Hyperkalemic cardioplegia-induced myocyte swelling and contractile dysfunction: prevention by diazoxide.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:1

    Topics: Animals; Benzamides; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Cell Size; Decanoic Aci

2006
Differential role of K(ATP) channels in late preconditioning against myocardial stunning and infarction in rabbits.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:5

    Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Diazoxide; Glyburide; Heart; Hemodynamics; Hydroxy

2000