diazoxide has been researched along with Heart Diseases in 7 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with diazoxide attenuates doxorubicin-induced cardiac dysfunction in the rat, measured by physiological indices and TnT and H2O2 in effluate from isolated hearts." | 1.40 | Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat. ( Fossan, KO; Hole, LD; Larsen, TH; Limé, F; Schjøtt, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wojtovich, AP | 1 |
| Urciuoli, WR | 1 |
| Chatterjee, S | 1 |
| Fisher, AB | 1 |
| Nehrke, K | 1 |
| Brookes, PS | 1 |
| Hole, LD | 1 |
| Larsen, TH | 1 |
| Fossan, KO | 1 |
| Limé, F | 1 |
| Schjøtt, J | 1 |
| Jašová, M | 1 |
| Kancirová, I | 1 |
| Muráriková, M | 1 |
| Farkašová, V | 1 |
| Waczulíková, I | 1 |
| Ravingerová, T | 1 |
| Ziegelhöffer, A | 1 |
| Ferko, M | 1 |
| Ichinose, M | 1 |
| Yonemochi, H | 1 |
| Sato, T | 1 |
| Saikawa, T | 1 |
| Jones, RM | 1 |
| Becker, CE | 1 |
| Benowitz, NL | 1 |
| Finnerty, FA | 1 |
7 other studies available for diazoxide and Heart Diseases
| Article | Year |
|---|---|
Kir6.2 is not the mitochondrial KATP channel but is required for cardioprotection by ischemic preconditioning.
Topics: Anesthesia; Anesthetics; Animals; Cardiac Pacing, Artificial; Diazoxide; Electrocardiography; Ethano | 2013 |
Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat.
Topics: Animals; Antibiotics, Antineoplastic; Cardiotonic Agents; Diazoxide; Doxorubicin; Heart; Heart Disea | 2014 |
Stimulation of mitochondrial ATP synthase activity - a new diazoxide-mediated mechanism of cardioprotection.
Topics: Animals; Diabetes Mellitus, Experimental; Diazoxide; Heart Diseases; Male; Membrane Fluidity; Mitoch | 2016 |
Diazoxide triggers cardioprotection against apoptosis induced by oxidative stress.
Topics: Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Diazoxide; Diuretics; Flow Cytometry; Heart D | 2003 |
ECT for patients with hypertensive heart disease.
Topics: Aged; Coronary Disease; Diazoxide; Electroconvulsive Therapy; Heart Diseases; Humans; Hypertension; | 1983 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases | 1979 |
Hypertensive encephalopathy.
Topics: Anxiety; Brain Diseases; Brain Edema; Coma; Diazoxide; Female; Furosemide; Glomerulonephritis; Heada | 1972 |