Page last updated: 2024-10-25

diazoxide and Glucose Intolerance

diazoxide has been researched along with Glucose Intolerance in 4 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Veiguela Blanco, B1
Felechosa, MD1
García Moreira, V1
Ramanathan, RP1
Arbeláez, AM1
Cryer, PE1
Alemzadeh, R1
Tushaus, KM1
Huang, Q1
Bu, S1
Yu, Y1
Guo, Z1
Ghatnekar, G1
Bu, M1
Yang, L1
Lu, B1
Feng, Z1
Liu, S1
Wang, F1

Reviews

1 review available for diazoxide and Glucose Intolerance

ArticleYear
Autoimmune hypoglycemia due to anti-insulin antibodies.
    Medicina clinica, 2018, 06-22, Volume: 150, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Autoimmune Dis

2018

Trials

1 trial available for diazoxide and Glucose Intolerance

ArticleYear
Partial inhibition of insulin secretion results in glucose intolerance but not hyperglucagonemia.
    Diabetes, 2011, Volume: 60, Issue:4

    Topics: Adult; Blood Glucose; C-Peptide; Diazoxide; Female; Glucagon; Glucose Intolerance; Humans; Hypoglyce

2011

Other Studies

2 other studies available for diazoxide and Glucose Intolerance

ArticleYear
Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxide.
    Endocrinology, 2004, Volume: 145, Issue:12

    Topics: Adenylyl Cyclases; Adiponectin; Adipose Tissue; Animals; Blood Glucose; Body Weight; Diabetes Mellit

2004
Diazoxide prevents diabetes through inhibiting pancreatic beta-cells from apoptosis via Bcl-2/Bax rate and p38-beta mitogen-activated protein kinase.
    Endocrinology, 2007, Volume: 148, Issue:1

    Topics: Animals; Antihypertensive Agents; Apoptosis; Area Under Curve; bcl-2-Associated X Protein; Blood Glu

2007