diazoxide has been researched along with Fetal Macrosomia in 2 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Fetal Macrosomia: A condition of fetal overgrowth leading to a large-for-gestational-age FETUS. It is defined as BIRTH WEIGHT greater than 4,000 grams or above the 90th percentile for population and sex-specific growth curves. It is commonly seen in GESTATIONAL DIABETES; PROLONGED PREGNANCY; and pregnancies complicated by pre-existing diabetes mellitus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This case series follows the evolving course of three patients with confirmed HNF4A-mediated congenital hyperinsulinism, highlighting (1) the variable natural history of these mutations, (2) the potential for prolonged diazoxide requirement, even into adolescence, and (3) the need for screening, regardless of family history." | 3.80 | The evolving course of HNF4A hyperinsulinaemic hypoglycaemia--a case series. ( Ellard, S; Flanagan, SE; Hawkes, CP; McDonnell, CM; McGlacken-Byrne, SM; Murphy, NP, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khoriati, D | 1 |
| Arya, VB | 1 |
| Flanagan, SE | 2 |
| Ellard, S | 2 |
| Hussain, K | 1 |
| McGlacken-Byrne, SM | 1 |
| Hawkes, CP | 1 |
| McDonnell, CM | 1 |
| Murphy, NP | 1 |
2 other studies available for diazoxide and Fetal Macrosomia
| Article | Year |
|---|---|
Prematurity, macrosomia, hyperinsulinaemic hypoglycaemia and a dominant ABCC8 gene mutation.
Topics: Antihypertensive Agents; ATP-Binding Cassette Transporters; Chlorothiazide; Congenital Hyperinsulini | 2013 |
The evolving course of HNF4A hyperinsulinaemic hypoglycaemia--a case series.
Topics: Age of Onset; Antihypertensive Agents; Birth Weight; Blood Glucose; Child; Child, Preschool; Congeni | 2014 |