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diazoxide and Fetal Macrosomia

diazoxide has been researched along with Fetal Macrosomia in 2 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Fetal Macrosomia: A condition of fetal overgrowth leading to a large-for-gestational-age FETUS. It is defined as BIRTH WEIGHT greater than 4,000 grams or above the 90th percentile for population and sex-specific growth curves. It is commonly seen in GESTATIONAL DIABETES; PROLONGED PREGNANCY; and pregnancies complicated by pre-existing diabetes mellitus.

Research Excerpts

ExcerptRelevanceReference
"This case series follows the evolving course of three patients with confirmed HNF4A-mediated congenital hyperinsulinism, highlighting (1) the variable natural history of these mutations, (2) the potential for prolonged diazoxide requirement, even into adolescence, and (3) the need for screening, regardless of family history."3.80The evolving course of HNF4A hyperinsulinaemic hypoglycaemia--a case series. ( Ellard, S; Flanagan, SE; Hawkes, CP; McDonnell, CM; McGlacken-Byrne, SM; Murphy, NP, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khoriati, D1
Arya, VB1
Flanagan, SE2
Ellard, S2
Hussain, K1
McGlacken-Byrne, SM1
Hawkes, CP1
McDonnell, CM1
Murphy, NP1

Other Studies

2 other studies available for diazoxide and Fetal Macrosomia

ArticleYear
Prematurity, macrosomia, hyperinsulinaemic hypoglycaemia and a dominant ABCC8 gene mutation.
    BMJ case reports, 2013, Apr-05, Volume: 2013

    Topics: Antihypertensive Agents; ATP-Binding Cassette Transporters; Chlorothiazide; Congenital Hyperinsulini

2013
The evolving course of HNF4A hyperinsulinaemic hypoglycaemia--a case series.
    Diabetic medicine : a journal of the British Diabetic Association, 2014, Volume: 31, Issue:1

    Topics: Age of Onset; Antihypertensive Agents; Birth Weight; Blood Glucose; Child; Child, Preschool; Congeni

2014