diazoxide and Emergencies studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Emergencies: Situations or conditions requiring immediate intervention to avoid serious adverse results.

Research Excerpts

Excerpt	Relevance	Reference
"The administration of diazoxide to patients with severe hypertension in pregnancy in 60 and 150 mg doses, which are smaller than the usual 300 mg dose, is described."	9.05	Low-dose diazoxide in the emergency management of severe hypertension in pregnancy. ( Moodley, J; Sankar, D, 1984)
"The administration of diazoxide to patients with severe hypertension in pregnancy in 60 and 150 mg doses, which are smaller than the usual 300 mg dose, is described."	5.05	Low-dose diazoxide in the emergency management of severe hypertension in pregnancy. ( Moodley, J; Sankar, D, 1984)
"Although hypertension is the most common and significant risk factor in pregnancy, the risks can be minimized with careful supervision and therapy."	2.37	Hypertension in pregnant women. ( Gallery, ED, 1985)
"Diazoxide has the advantage compared with nitroprusside sodium that an intravenous injection decreases the blood pressure for several hours."	1.26	[Hypertensive crisis and its treatment]. ( de Châtel, R, 1980)

Timeframe	Studies, this research(%)	All Research%
pre-1990	44 (93.62)	18.7374
1990's	2 (4.26)	18.2507
2000's	1 (2.13)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Ram, CV	2
Strandgaard, S	1
Sankar, D	1
Moodley, J	1
Segal, JL	1
Schranz, W	1
de Châtel, R	1
Meurer, KA	1
Grim, CE	1
Frank, GW	1
Nies, AS	1
Rowe, WS	1
Romankiewicz, JA	2
Golikov, AP	1
Babkov, VK	1
Borisenko, AP	1
Ivleva, VI	1
Bedani, PL	1
Farinelli, A	1
Becker, CE	1
Benowitz, NL	1
Bock, KD	1
Koch-Weser, J	2
Thien, T	1
Koene, RA	1
Wijdeveld, PG	1
Schalekamp, MA	1
Man In 'T Veld, AJ	1
Wenting, GJ	1
Verhoeven, RP	1
de Bruyn, JH	1
Pascual, AV	1
Zimmerman, SW	1
Diekmann, L	1
Curry, CL	1
McLain, LG	1
Skórka, B	1
Chodakowska, J	1
Januszewicz, W	1
Deal, JE	1
Barratt, TM	1
Dillon, MJ	1
Tsuyusaki, T	1
Gallery, ED	1
Ferguson, RK	1
Vlasses, PH	1
Vidt, DG	2
Meese, RB	1
Burris, JF	1
Philipp, T	1
Nast, HP	1
Fernandes, M	1
Kim, KE	1
Moyer, JH	1
Pennington, JC	1
Picker, RH	1
Throne, ML	1
Breslin, DJ	1
Himathongkam, T	1
Saker, BM	1
Mathew, TH	1
Eremin, J	1
Kincaid-Smith, P	1
Finnerty, FA	1

Article	Year
Hypertensive crisis. Cardiology clinics, 1984, Volume: 2, Issue:2 Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia	1984
Hypertensive emergencies: practical approach to treatment. Postgraduate medicine, 1980, Volume: 68, Issue:2 Topics: Administration, Oral; Antihypertensive Agents; Child; Clonidine; Diazoxide; Emergencies; Female; Hum	1980
Clinical pharmacology of antihypertensive drugs. The Medical clinics of North America, 1977, Volume: 61, Issue:3 Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blo	1977
Drug therapy reviews. Pharmacology and clinical use of drugs in hypertensive emergencies. The Journal of the Maine Medical Association, 1977, Volume: 68, Issue:2 Topics: Adult; Diazoxide; Emergencies; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Nitroprus	1977
Pharmacology and clinical use of drugs in hypertensive emergencies. American journal of hospital pharmacy, 1977, Volume: 34, Issue:2 Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Aorta; Brain Diseases; Cerebral Hemorrhage; Diazox	1977
Diazoxide. The New England journal of medicine, 1976, Jun-03, Volume: 294, Issue:23 Topics: Blood Pressure; Cardiac Output; Diazoxide; Diuretics; Drug Synergism; Emergencies; Female; Half-Life	1976
How to manage hypertensive emergencies and urgencies. Geriatrics, 1976, Volume: 31, Issue:1 Topics: Adult; Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxid	1976
Hypertension in pregnant women. The Medical journal of Australia, 1985, Jul-08, Volume: 143, Issue:1 Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Delivery, Obstetric; Diazoxide; Emergencies; F	1985
Hypertensive emergencies and urgencies. JAMA, 1986, Mar-28, Volume: 255, Issue:12 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers;	1986
Hypertensive cardiovascular emergencies. Comprehensive therapy, 1985, Volume: 11, Issue:10 Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia	1985
Choice of antihypertensive drugs for the treatment of hypertension, including hypertensive emergencies. Cardiovascular clinics, 1974, Volume: 6, Issue:2 Topics: Antihypertensive Agents; Bethanechol Compounds; Clonidine; Diazoxide; Diuretics; Emergencies; Ferric	1974
Hypertensive emergencies. The New England journal of medicine, 1974, Jan-24, Volume: 290, Issue:4 Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Coronary D	1974
Hypertensive emergencies. Pennsylvania medicine, 1974, Volume: 77, Issue:7 Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume	1974
Hypertensive crisis. The Medical clinics of North America, 1969, Volume: 53, Issue:2 Topics: Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Diazoxide; Emergencies; Humans; Hyd	1969

Article	Year
Cerebral symptoms and blood pressure during parenteral administration of chlorpromazine, dihydralazine and diazoxide. Danish multicenter study on acute severe hypertension. Acta medica Scandinavica. Supplementum, 1983, Volume: 678 Topics: Blood Pressure; Brain Diseases; Brain Ischemia; Chlorpromazine; Clinical Trials as Topic; Diazoxide;	1983
Low-dose diazoxide in the emergency management of severe hypertension in pregnancy. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Feb-25, Volume: 65, Issue:8 Topics: Blood Pressure; Diazoxide; Emergencies; Female; Fetal Heart; Heart Rate; Humans; Hypertension; Pregn	1984
[Use of Hyperstat for arresting hypertensive crises]. Kardiologiia, 1978, Volume: 18, Issue:11 Topics: Adrenal Glands; Adult; Aged; Clinical Trials as Topic; Diazoxide; Drug Evaluation; Emergencies; Fema	1978
[Diazoxide in arterial hypertensive emergencies]. La Clinica terapeutica, 1979, May-15, Volume: 89, Issue:3 Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diazoxide; Emergencies; Fe	1979

Article	Year
Cerebral blood flow in hypertension. Acta medica Scandinavica. Supplementum, 1983, Volume: 678 Topics: Antihypertensive Agents; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Disorders; Dia	1983
[Vision disorders--nausea--chest pain]. Fortschritte der Medizin, 1982, Jun-17, Volume: 100, Issue:23 Topics: Diazoxide; Dihydralazine; Emergencies; Furosemide; Humans; Hypertension; Male; Middle Aged; Nausea;	1982
[Hypertensive crisis and its treatment]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1980, Oct-01, Volume: 35, Issue:19 Topics: Antihypertensive Agents; Diazoxide; Dihydralazine; Emergencies; Humans; Hypertension; Nitroprusside;	1980
[Emergencies in arterial hypertension]. Die Medizinische Welt, 1980, Jan-18, Volume: 31, Issue:3 Topics: Aortic Aneurysm; Aortic Dissection; Cerebral Hemorrhage; Cerebral Infarction; Diazoxide; Emergencies	1980
Emergency treatment of severe or malignant hypertension. Geriatrics, 1980, Volume: 35, Issue:12 Topics: Aged; Antihypertensive Agents; Diazoxide; Emergencies; Furosemide; Humans; Hypertension, Malignant;	1980
Diazoxide and trimethaphan used? Chest, 2001, Volume: 119, Issue:1 Topics: Critical Care; Diazoxide; Emergencies; Humans; Hypertension; Trimethaphan	2001
Some aspects of the management of hypertension. 1. General considerations. The Medical journal of Australia, 1975, Feb-22, Volume: 1, Issue:8 Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Clonidine; Dia	1975
Hypertensive emergencies. The Medical clinics of North America, 1979, Volume: 63, Issue:1 Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases	1979
[Treatment of hypertensive emergencies]. Medizinische Klinik, 1978, Mar-17, Volume: 73, Issue:11 Topics: Clonidine; Diazoxide; Emergencies; Family Practice; Furosemide; Hospitalization; Humans; Hypertensio	1978
[Treatment of hypertensive crisis by means of intravenous administration of diazoxide]. Nederlands tijdschrift voor geneeskunde, 1977, Dec-17, Volume: 121, Issue:51 Topics: Diazoxide; Emergencies; Humans; Hypertension; Injections, Intravenous	1977
Hypertensive emergencies. The Netherlands journal of medicine, 1977, Volume: 20, Issue:4-5 Topics: Antihypertensive Agents; Blood Pressure; Brain Diseases; Diazoxide; Dihydralazine; Emergencies; Huma	1977
Treatment of hypertensive emergencies. Wisconsin medical journal, 1975, Volume: 74, Issue:7 Topics: Diazoxide; Emergencies; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Reserpine; Tri	1975
[The acute crisis of blood pressure and its treatment in childhood (authors transl)]. Klinische Padiatrie, 1975, Volume: 187, Issue:2 Topics: Acute Disease; Acute Kidney Injury; Administration, Oral; Adolescent; Age Factors; Child; Diazoxide;	1975
Current treatment of malignant hypertension. JAMA, 1975, Jun-30, Volume: 232, Issue:13 Topics: Acute Disease; Administration, Oral; Antihypertensive Agents; Blood Pressure; Diazoxide; Diuretics;	1975
Drugs in the management of hypertensive emergencies in children. Notes and comments on currently popular agents. Clinical pediatrics, 1976, Volume: 15, Issue:1 Topics: Antihypertensive Agents; Child; Diazoxide; Diuretics; Drug Combinations; Drug Therapy, Combination;	1976
[Effects of emergency treatment of hypertension with diazoxide]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1976, Jan-12, Volume: 31, Issue:2 Topics: Adolescent; Adult; Diazoxide; Emergencies; Female; Humans; Hypertension; Male; Middle Aged	1976
Management of hypertensive emergencies. Archives of disease in childhood, 1992, Volume: 67, Issue:9 Topics: Adolescent; Child; Child, Preschool; Diazoxide; Emergencies; Female; Humans; Hydralazine; Hypertensi	1992
[Hypertensive emergencies]. Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl Topics: Adrenal Gland Neoplasms; Cerebrovascular Circulation; Diazoxide; Emergencies; Female; Humans; Hypert	1992
Current concepts in treatment of hypertensive emergencies. American heart journal, 1986, Volume: 111, Issue:1 Topics: Diazoxide; Drug Therapy, Combination; Emergencies; Humans; Hydralazine; Hypertension; Labetalol; Met	1986
Drugs for hypertensive emergencies. The Medical letter on drugs and therapeutics, 1985, Mar-01, Volume: 27, Issue:682 Topics: Administration, Oral; Captopril; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hypertensio	1985
Hypertensive emergencies. American family physician, 1985, Volume: 32, Issue:1 Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hyp	1985
[Hypertensive emergencies]. Der Internist, 1974, Volume: 15, Issue:3 Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies;	1974
The treatment of malignant hypertension and hypertensive emergencies. A statement by the AMA committee on hypertension. JAMA, 1974, Jun-24, Volume: 228, Issue:13 Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Diazoxide; Drug Evaluation; Emergenci	1974
Diazoxide and the treatment of the acute hypertensive emergency in obstetrics. The Medical journal of Australia, 1972, Nov-04, Volume: 2, Issue:19 Topics: Acute Disease; Adolescent; Adult; Diazoxide; Eclampsia; Emergencies; Female; Humans; Hypertension; I	1972
Evaluation of diazoxide. (Hyperstat I.V.). JAMA, 1973, Jun-04, Volume: 224, Issue:10 Topics: Administration, Oral; Age Factors; Blood Pressure; Cardiac Output; Child; Diazoxide; Emergencies; Ev	1973
Diazoxide. Journal of the Medical Association of Georgia, 1973, Volume: 62, Issue:11 Topics: Diazoxide; Emergencies; Humans; Hypertension; Injections, Intravenous	1973
Hypertensive emergencies. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1972, Volume: 55, Issue:8 Topics: Diazoxide; Emergencies; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension	1972
Diazoxide in the treatment of the acute hypertensive emergency. The Medical journal of Australia, 1968, Apr-06, Volume: 1, Issue:14 Topics: Adolescent; Adult; Blood Pressure; Diazoxide; Emergencies; Female; Glomerulonephritis; Humans; Hyper	1968
Hypertensive emergencies. The American journal of cardiology, 1966, Volume: 17, Issue:5 Topics: Antihypertensive Agents; Diazoxide; Emergencies; Humans; Hypertension; Injections, Intramuscular; In	1966

diazoxide and Emergencies

Research Excerpts

Research

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