Page last updated: 2024-10-25

diazoxide and Embryopathies

diazoxide has been researched along with Embryopathies in 3 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Research Excerpts

ExcerptRelevanceReference
"Diazoxide is one such treatment that acts on the pancreatic β-cell in a dose-dependent manner to decrease insulin secretion."3.11Oral diazoxide versus placebo for severe or recurrent neonatal hypoglycaemia: Neonatal Glucose Care Optimisation (NeoGluCO) study - a randomised controlled trial. ( Alsweiler, JM; Ardern, J; Chase, JG; Cutfield, WS; Gamble, GD; Hanning, SM; Harding, JE; Laing, D; McKinlay, CJ; Meyer, MP; Rogers, J; Walsh, E, 2022)
"Hypertension in pregnancy has implications for both maternal and fetal welfare."2.37Hypertension in pregnancy. Pathophysiology and management. ( Lubbe, WF, 1984)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Laing, D1
Walsh, E1
Alsweiler, JM1
Hanning, SM1
Meyer, MP1
Ardern, J1
Cutfield, WS1
Rogers, J1
Gamble, GD1
Chase, JG1
Harding, JE1
McKinlay, CJ1
Solís-García, G1
Yeung, T1
Jasani, B1
Lubbe, WF1

Reviews

1 review available for diazoxide and Embryopathies

ArticleYear
Hypertension in pregnancy. Pathophysiology and management.
    Drugs, 1984, Volume: 28, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Clon

1984

Trials

1 trial available for diazoxide and Embryopathies

ArticleYear
Oral diazoxide versus placebo for severe or recurrent neonatal hypoglycaemia: Neonatal Glucose Care Optimisation (NeoGluCO) study - a randomised controlled trial.
    BMJ open, 2022, 08-17, Volume: 12, Issue:8

    Topics: Blood Glucose; Diazoxide; Double-Blind Method; Female; Fetal Diseases; Glucose; Humans; Hypoglycemia

2022

Other Studies

1 other study available for diazoxide and Embryopathies

ArticleYear
Does the use of diazoxide for hyperinsulinaemic hypoglycaemia increase the risk of necrotising enterocolitis in neonates?
    Archives of disease in childhood, 2023, Volume: 108, Issue:9

    Topics: Diazoxide; Enterocolitis, Necrotizing; Female; Fetal Diseases; Humans; Hypoglycemia; Infant, Newborn

2023