diazoxide has been researched along with Embryopathies in 3 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazoxide is one such treatment that acts on the pancreatic β-cell in a dose-dependent manner to decrease insulin secretion." | 3.11 | Oral diazoxide versus placebo for severe or recurrent neonatal hypoglycaemia: Neonatal Glucose Care Optimisation (NeoGluCO) study - a randomised controlled trial. ( Alsweiler, JM; Ardern, J; Chase, JG; Cutfield, WS; Gamble, GD; Hanning, SM; Harding, JE; Laing, D; McKinlay, CJ; Meyer, MP; Rogers, J; Walsh, E, 2022) |
| "Hypertension in pregnancy has implications for both maternal and fetal welfare." | 2.37 | Hypertension in pregnancy. Pathophysiology and management. ( Lubbe, WF, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Laing, D | 1 |
| Walsh, E | 1 |
| Alsweiler, JM | 1 |
| Hanning, SM | 1 |
| Meyer, MP | 1 |
| Ardern, J | 1 |
| Cutfield, WS | 1 |
| Rogers, J | 1 |
| Gamble, GD | 1 |
| Chase, JG | 1 |
| Harding, JE | 1 |
| McKinlay, CJ | 1 |
| Solís-García, G | 1 |
| Yeung, T | 1 |
| Jasani, B | 1 |
| Lubbe, WF | 1 |
1 review available for diazoxide and Embryopathies
| Article | Year |
|---|---|
Hypertension in pregnancy. Pathophysiology and management.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Clon | 1984 |
1 trial available for diazoxide and Embryopathies
| Article | Year |
|---|---|
Oral diazoxide versus placebo for severe or recurrent neonatal hypoglycaemia: Neonatal Glucose Care Optimisation (NeoGluCO) study - a randomised controlled trial.
Topics: Blood Glucose; Diazoxide; Double-Blind Method; Female; Fetal Diseases; Glucose; Humans; Hypoglycemia | 2022 |
1 other study available for diazoxide and Embryopathies
| Article | Year |
|---|---|
Does the use of diazoxide for hyperinsulinaemic hypoglycaemia increase the risk of necrotising enterocolitis in neonates?
Topics: Diazoxide; Enterocolitis, Necrotizing; Female; Fetal Diseases; Humans; Hypoglycemia; Infant, Newborn | 2023 |