diazoxide has been researched along with Electrolytes in 11 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of diazoxide, a benzothiadiazine derivative, on the blood pressure, excretion of Na+, K+, and Ca2+, and the levels of these electrolytes in serum, kidney, and aorta were studied in rats with deoxycorticosterone acetate (DOCA)-induced hypertension in comparison with rats treated with hydrochlorothiazide." | 7.69 | Effect of diazoxide on serum and tissue electrolyte levels in rats with deoxycorticosterone acetate-induced hypertension. ( Nakai, T, 1994) |
| "The protective effects of diazoxide were primarily manifest as a better preservation of diastolic function and a reduction of myocardial edema." | 3.70 | Opening of mitochondrial potassium channels: a new target for graft preservation strategies? ( Kevelaitis, E; Menasché, P; Mouas, C; Oubenaissa, A; Peynet, J, 2000) |
| "Effects of diazoxide, a benzothiadiazine derivative, on the blood pressure, excretion of Na+, K+, and Ca2+, and the levels of these electrolytes in serum, kidney, and aorta were studied in rats with deoxycorticosterone acetate (DOCA)-induced hypertension in comparison with rats treated with hydrochlorothiazide." | 3.69 | Effect of diazoxide on serum and tissue electrolyte levels in rats with deoxycorticosterone acetate-induced hypertension. ( Nakai, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, L | 1 |
| Han, F | 1 |
| Mandal, A | 1 |
| Rao, GN | 1 |
| Zhang, X | 1 |
| Yang, F | 1 |
| Chen, WL | 1 |
| Zheng, MZ | 1 |
| Yu, GW | 1 |
| Xu, HJ | 1 |
| Shen, YL | 1 |
| Chen, YY | 1 |
| GILLENWATER, JY | 1 |
| Nakai, T | 1 |
| Kitano, I | 1 |
| Mori, N | 1 |
| Matsunaga, T | 1 |
| Kevelaitis, E | 2 |
| Oubenaissa, A | 2 |
| Mouas, C | 2 |
| Peynet, J | 2 |
| Menasché, P | 2 |
| Heller, J | 1 |
| Tata, PS | 1 |
| Ganten, D | 1 |
| Meurer, KA | 1 |
| Kaufmann, W | 1 |
| Vargas, R | 1 |
| Carrillo, R | 1 |
| Pardo, EG | 1 |
| Thompson, GR | 1 |
| Anderson, RW | 1 |
| Ballantyne, LM | 1 |
1 trial available for diazoxide and Electrolytes
| Article | Year |
|---|---|
[Hemodynamics and excretory function of the kidney during furosemide and diazoxide administration. A contribution to the regulation of renin activity].
Topics: Diazoxide; Electrolytes; Furosemide; Hemodynamics; Humans; Hypertension; Kidney; Renin | 1971 |
10 other studies available for diazoxide and Electrolytes
| Article | Year |
|---|---|
Diazoxide attenuates hypothermic preservation-induced renal injury via down-regulation of CHOP and caspase-12.
Topics: Acute Kidney Injury; Animals; Apoptosis; Caspase 12; Cryoprotective Agents; Diazoxide; Disaccharides | 2010 |
Heat shock protein 90 mediates anti-apoptotic effect of diazoxide by preventing the cleavage of Bid in hypothermic preservation rat hearts.
Topics: Animals; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Cold Temperature; Connexin 43; Dia | 2011 |
THE ANTIDIURETIC PROPERTIES OF CHLOROTHIAZIDE IN DIABETES INSIPIDUS DOGS. I. EFFECT ON SOLUTE, WATER, AND ELECTROLYTE EXCRETION. REP 582.
Topics: Animals; Bendroflumethiazide; Blood Volume; Body Fluids; Chlorothiazide; Chlorthalidone; Diabetes In | 1963 |
Effect of diazoxide on serum and tissue electrolyte levels in rats with deoxycorticosterone acetate-induced hypertension.
Topics: Animals; Aorta; Blood Pressure; Calcium; Desoxycorticosterone; Diazoxide; Electrolytes; Hydrochlorot | 1994 |
Role of ATP-sensitive K+ channels in anoxia-sensitive negative potential of endolymph.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Basal Ganglia; Cell Hypoxia; Cochlea; Diaz | 1995 |
Opening of mitochondrial potassium channels: a new target for graft preservation strategies?
Topics: Analysis of Variance; Animals; Diazoxide; Disaccharides; Edema; Electrolytes; Endothelium, Vascular; | 2000 |
Ischemic preconditioning with opening of mitochondrial adenosine triphosphate-sensitive potassium channels or Na/H exchange inhibition: which is the best protective strategy for heart transplants?
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Creatine Kinase; Diaz | 2001 |
The changes of electrolyte and urea concentration gradients in the rat kidney after injection of diazoxid, phenylbutazon and indomethacin.
Topics: Animals; Diazoxide; Diuretics; Electrolytes; Indomethacin; Kidney; Natriuresis; Osmolar Concentratio | 1968 |
[The mechanism of the hypotensive action of thiazides].
Topics: Animals; Blood Pressure; Catecholamines; Chlorothiazide; Diazoxide; Diuresis; Dogs; Electrolytes; He | 1965 |
The effects of intra-venous diazoxide, a non-diuretic thiazide, upon blood pressure, electrolyte, and uric acid excretion.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorothiazide; Diazoxide; Electrolytes; Humans; Hyp | 1966 |