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diazoxide and Edema-Proteinuria-Hypertension Gestosis

diazoxide has been researched along with Edema-Proteinuria-Hypertension Gestosis in 42 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Research Excerpts

ExcerptRelevanceReference
"Eight patients with severe pre-eclampsia or eclampsia were treated with diazoxide."7.66Infusion of diazoxide in severe hypertension during pregnancy. ( Eskes, TK; Koene, RA; Pieters, GF; Schijf, C; Thien, T; Wijdeveld, PG, 1980)
"Twelve patients with either severe preeclampsia (9) or eclampsia (3) were treated with intravenous diazoxide, 300-mg bolus, for the reduction of diastolic blood pressure (less than or equal 110 torr) after the usual and customary measures had been initiated to include parenteral MgSO4 and diazepam."7.65The management of severe preeclampsia and eclampsia with intravenous diazoxide. ( Arce, JJ; Bloom, RS; Clark, JH; Davidson, EC; Hamilton, CJ; Maidman, JE; Morris, JA, 1977)
"Treatment with oral diazoxide for periods of 4 to 10 weeks in hospital allowed adequate control of hypertension with continuation of fetal growth in four patients with severe toxaemia."7.65Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy. ( Davis, D; Morgan, MY; Pohl, JE; Thurston, H, 1972)
"Eight patients with severe pre-eclampsia or eclampsia were treated with diazoxide."3.66Infusion of diazoxide in severe hypertension during pregnancy. ( Eskes, TK; Koene, RA; Pieters, GF; Schijf, C; Thien, T; Wijdeveld, PG, 1980)
"Twelve patients with either severe preeclampsia (9) or eclampsia (3) were treated with intravenous diazoxide, 300-mg bolus, for the reduction of diastolic blood pressure (less than or equal 110 torr) after the usual and customary measures had been initiated to include parenteral MgSO4 and diazepam."3.65The management of severe preeclampsia and eclampsia with intravenous diazoxide. ( Arce, JJ; Bloom, RS; Clark, JH; Davidson, EC; Hamilton, CJ; Maidman, JE; Morris, JA, 1977)
"Treatment with oral diazoxide for periods of 4 to 10 weeks in hospital allowed adequate control of hypertension with continuation of fetal growth in four patients with severe toxaemia."3.65Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy. ( Davis, D; Morgan, MY; Pohl, JE; Thurston, H, 1972)
"While nitroprusside is commonly used to treat severe hypertension, it is an extremely toxic drug that should only be used in rare circumstances."2.41The diagnosis and management of hypertensive crises. ( Marik, PE; Varon, J, 2000)
"Although hypertension is the most common and significant risk factor in pregnancy, the risks can be minimized with careful supervision and therapy."2.37Hypertension in pregnant women. ( Gallery, ED, 1985)
"Treatment with diazoxide could be continued in four of these."1.25Development of extrapyramidal symptoms in hypertensive patients treated with diazoxide. ( Neary, D; Pohl, JE; Thurston, H, 1973)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199040 (95.24)18.7374
1990's1 (2.38)18.2507
2000's1 (2.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FINNERTY, FA4
KAKAVIATOS, N1
TUCKMAN, J1
MAGILL, J1
Moodley, J1
Chesley, LC1
Redman, CW4
Zamora Orozco, J1
Castelazo, JM1
Mata Palomino, C1
Arrieta Núñez, JM1
MacLean, AB1
Doig, JR1
Chatfield, WR1
Aickin, DR1
Berkowitz, RL1
Thien, T1
Koene, RA1
Schijf, C1
Pieters, GF1
Eskes, TK1
Wijdeveld, PG1
Tasić, D1
Meurer, KA1
Varon, J1
Marik, PE1
Romankiewicz, JA1
Becker, CE1
Benowitz, NL1
Perkins, RP2
Tiller, DJ2
Korda, AR1
Horvath, JS2
Morris, JA1
Arce, JJ1
Hamilton, CJ1
Davidson, EC1
Maidman, JE1
Clark, JH1
Bloom, RS1
Leibovici, H1
Boner, G1
Grunstein, S1
Anderman, S1
Woods, JR1
Brinkman, CR1
Johnson, RA1
Tsuyusaki, T1
Gallery, ED1
Naden, RP1
Rubin, PC1
Korda, A1
Child, A1
Henderson-Smart, D1
Phippard, A1
Duggin, GG1
Hall, BM1
Kincaid-Smith, P2
Martin, JD1
Michael, CA2
Pennington, JC1
Picker, RH1
Neary, D1
Thurston, H2
Pohl, JE2
Davis, D1
Morgan, MY1
Mathew, TH1
Vorburger, C1

Reviews

12 reviews available for diazoxide and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
The management of hypertension in pregnancy: A review.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jul-19, Volume: 58, Issue:3

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anesthesia, Epidural; Anesthesia, Obstetrical; Anticoagu

1980
The control of hypertension in pregnancy.
    Obstetrics and gynecology annual, 1981, Volume: 10

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsi

1981
The management of hypertension in pregnancy.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1984, Volume: 169

    Topics: Cerebrovascular Circulation; Clinical Trials as Topic; Diazoxide; Diuretics; Female; Humans; Hydrala

1984
Anti-hypertensive drugs in the pregnant patient.
    Obstetrical & gynecological survey, 1980, Volume: 35, Issue:4

    Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide

1980
Treatment of hypertension in pregnancy.
    Kidney international, 1980, Volume: 18, Issue:2

    Topics: Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertension; Methyldopa; Placenta; Pre-Eclampsia

1980
The diagnosis and management of hypertensive crises.
    Chest, 2000, Volume: 118, Issue:1

    Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Fema

2000
The use of antihypertensive drugs in hypertension in pregnancy.
    Clinics in obstetrics and gynaecology, 1977, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretic

1977
Pharmacology and clinical use of drugs in hypertensive emergencies.
    American journal of hospital pharmacy, 1977, Volume: 34, Issue:2

    Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Aorta; Brain Diseases; Cerebral Hemorrhage; Diazox

1977
Hypertension in pregnant women.
    The Medical journal of Australia, 1985, Jul-08, Volume: 143, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Delivery, Obstetric; Diazoxide; Emergencies; F

1985
Antihypertensive drugs in pregnancy.
    Clinics in perinatology, 1985, Volume: 12, Issue:3

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Fetus; Humans; H

1985
Treatment of hypertension in pregnancy.
    Clinics in obstetrics and gynaecology, 1986, Volume: 13, Issue:2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsia; Female; Human

1986
Diazoxide: a review of its pharmacological properties and therapeutic use in hypertensive crises.
    Drugs, 1971, Volume: 2, Issue:2

    Topics: Acute Kidney Injury; Animals; Blood Glucose; Cardiovascular Diseases; Cats; Cyclic AMP; Diazoxide; D

1971

Trials

1 trial available for diazoxide and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
The management of hypertension in pregnancy.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1984, Volume: 169

    Topics: Cerebrovascular Circulation; Clinical Trials as Topic; Diazoxide; Diuretics; Female; Humans; Hydrala

1984

Other Studies

30 other studies available for diazoxide and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
CLINICAL EVALUATION OF DIAZOXIDE: A NEW TREATMENT FOR ACUTE HYPERTENSION.
    Circulation, 1963, Volume: 28

    Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Body Weight; Diazoxide; Femal

1963
[Use of vasodilators in the management of severe pre-eclampsia. 1. Diazoxide].
    Ginecologia y obstetricia de Mexico, 1983, Volume: 51, Issue:312

    Topics: Adolescent; Adult; Cesarean Section; Diazoxide; Female; Fetal Distress; Humans; Pre-Eclampsia; Pregn

1983
Small-dose diazoxide administration in pregnancy.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1981, Volume: 21, Issue:1

    Topics: Blood Pressure; Diazoxide; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complic

1981
Infusion of diazoxide in severe hypertension during pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 1980, Volume: 10, Issue:6

    Topics: Adult; Diazoxide; Eclampsia; Female; Humans; Hypertension; Infusions, Intra-Arterial; Pre-Eclampsia;

1980
Preeclampsia and eclampsia.
    The Western journal of medicine, 1981, Volume: 135, Issue:1

    Topics: Adult; Diazoxide; Eclampsia; Female; Humans; Hydralazine; Magnesium Sulfate; Pre-Eclampsia; Pregnanc

1981
[Use of diazoxide (Hyperstat) in the treatment of acute hypertensive states in pregnancy].
    Medicinski pregled, 1981, Volume: 34, Issue:1-2

    Topics: Adult; Diazoxide; Eclampsia; Female; Humans; Pre-Eclampsia; Pregnancy

1981
[Emergencies in arterial hypertension].
    Die Medizinische Welt, 1980, Jan-18, Volume: 31, Issue:3

    Topics: Aortic Aneurysm; Aortic Dissection; Cerebral Hemorrhage; Cerebral Infarction; Diazoxide; Emergencies

1980
Hypertensive emergencies.
    The Medical clinics of North America, 1979, Volume: 63, Issue:1

    Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases

1979
Treatment of toxemia of pregnancy.
    JAMA, 1977, Nov-14, Volume: 238, Issue:20

    Topics: Diazoxide; Female; Fetus; Humans; Hypertension; Pre-Eclampsia; Pregnancy

1977
Preeclampsia and eclampsia: a reply.
    The Medical journal of Australia, 1978, Jan-14, Volume: 1, Issue:1

    Topics: Diazoxide; Eclampsia; Female; Humans; Pre-Eclampsia; Pregnancy

1978
The management of severe preeclampsia and eclampsia with intravenous diazoxide.
    Obstetrics and gynecology, 1977, Volume: 49, Issue:6

    Topics: Adolescent; Adult; Cesarean Section; Diazoxide; Eclampsia; Female; Humans; Hypertension; Hypoglycemi

1977
Correspondence: Diazoxide in treatment of severe pre-eclampsia and hypertensive encephalopathy.
    American journal of obstetrics and gynecology, 1976, Sep-15, Volume: 126, Issue:2

    Topics: Animals; Child; Diazoxide; Dogs; Female; Fetus; Humans; Hypertension; Intracranial Pressure; Pre-Ecl

1976
[Diazoxide in severe hypertension during pregnancy].
    Harefuah, 1976, Nov-01, Volume: 91, Issue:9

    Topics: Acute Disease; Diazoxide; Female; Humans; Pre-Eclampsia; Pregnancy

1976
Hypertension in pregnancy.
    Clinical obstetrics and gynecology, 1975, Volume: 18, Issue:3

    Topics: Abortion, Therapeutic; Adult; Blood Pressure; Diazoxide; Diuretics; Female; Furosemide; Guanethidine

1975
The treatment of gestational hypertension.
    The Journal of reproductive medicine, 1975, Volume: 15, Issue:5

    Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype

1975
Adverse neonatal reaction to maternal administration of intravenous chlormethiazole and diazoxide.
    British medical journal, 1976, Apr-17, Volume: 1, Issue:6015

    Topics: Chlormethiazole; Diazoxide; Female; Fetus; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; P

1976
[Hypertensive emergencies].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Adrenal Gland Neoplasms; Cerebrovascular Circulation; Diazoxide; Emergencies; Female; Humans; Hypert

1992
Hypertension in pregnancy. A study of 142 women presenting before 32 weeks' gestation.
    The Medical journal of Australia, 1985, Jul-08, Volume: 143, Issue:1

    Topics: Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hydralazine; Hypertension; Infant Mor

1985
Management of severe hypertension.
    The American journal of cardiology, 1973, Sep-20, Volume: 32, Issue:4

    Topics: Benzothiadiazines; Blood Pressure; Clonidine; Diazoxide; Diet, Sodium-Restricted; Disseminated Intra

1973
Editorial: Hypertensive crises in pregnancy.
    The Medical journal of Australia, 1974, Aug-17, Volume: 2, Issue:7

    Topics: Anticonvulsants; Antihypertensive Agents; Diazoxide; Female; Ganglionic Blockers; Humans; Hypertensi

1974
A critical survey of drugs used in the treatment of hypertensive crises of pregnancy.
    The Medical journal of Australia, 1974, Aug-17, Volume: 2, Issue:7

    Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Barbiturates; Chlormethiazole; Clonidine; Diazepam;

1974
The control of hypertension in labour.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1972, Volume: 12, Issue:1

    Topics: Benzyl Compounds; Diazepam; Diazoxide; Drug Combinations; Female; Guanidines; Humans; Hypertension;

1972
Intravenous diazoxide in the treatment of severe pre-eclamptic toxaemia and eclampsia.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1973, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Delivery, Obstetric; Diazepam; Diazoxide; Eclampsia; Female; Fetal Death; Humans;

1973
Diazoxide and the treatment of the acute hypertensive emergency in obstetrics.
    The Medical journal of Australia, 1972, Nov-04, Volume: 2, Issue:19

    Topics: Acute Disease; Adolescent; Adult; Diazoxide; Eclampsia; Emergencies; Female; Humans; Hypertension; I

1972
Development of extrapyramidal symptoms in hypertensive patients treated with diazoxide.
    British medical journal, 1973, Sep-01, Volume: 3, Issue:5878

    Topics: Adult; Aged; Basal Ganglia Diseases; Diazepam; Diazoxide; Female; Humans; Hypertension; Hypertension

1973
Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy.
    British medical journal, 1972, Jun-03, Volume: 2, Issue:5813

    Topics: Acute Disease; Administration, Oral; Adult; Albuminuria; Blood Glucose; Diazoxide; Female; Furosemid

1972
Hypertensive encephalopathy.
    The American journal of medicine, 1972, Volume: 52, Issue:5

    Topics: Anxiety; Brain Diseases; Brain Edema; Coma; Diazoxide; Female; Furosemide; Glomerulonephritis; Heada

1972
The use of diazoxide in hypertensive crises with particular reference to the control of hypertension in severe renal failure.
    Drugs, 1971, Volume: 2, Issue:2

    Topics: Acute Kidney Injury; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Diazoxide; Femal

1971
Advantages and disadvantages of furosemide in the edematous states of pregnancy.
    American journal of obstetrics and gynecology, 1969, Dec-01, Volume: 105, Issue:7

    Topics: Diazoxide; Edema; Female; Furosemide; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Car

1969
[The hypertensive crisis. Urgent therapeutic measures].
    Therapeutische Umschau. Revue therapeutique, 1967, Volume: 24, Issue:5

    Topics: Antihypertensive Agents; Diazoxide; Drug Synergism; Female; Guanethidine; Humans; Hypertension; Male

1967