diazoxide has been researched along with Drug Overdose in 2 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with diazoxide is rational and effective and may be lifesaving." | 1.28 | Clinical spectrum of sulfonylurea overdose and experience with diazoxide therapy. ( Meatherall, RC; Palatnick, W; Tenenbein, M, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boyle, PJ | 1 |
| Justice, K | 1 |
| Krentz, AJ | 1 |
| Nagy, RJ | 1 |
| Schade, DS | 1 |
| Palatnick, W | 1 |
| Meatherall, RC | 1 |
| Tenenbein, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Randomized, Placebo (Saline)-Controlled, Balanced, 3-treatment Regimen Crossover Study Comparing the Effects of Prolonged (13 h) Hyperglucagonemia With Those of Acute (3 hr) Hyperglucagonemia on Energy Expenditure and Endogenous Glucose Prot[NCT02237053] | Phase 1 | 6 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for diazoxide and Drug Overdose
| Article | Year |
|---|---|
Octreotide reverses hyperinsulinemia and prevents hypoglycemia induced by sulfonylurea overdoses.
Topics: Adult; Blood Glucose; Diazoxide; Drug Overdose; Female; Glucose; Humans; Hyperinsulinism; Hypoglycem | 1993 |
Clinical spectrum of sulfonylurea overdose and experience with diazoxide therapy.
Topics: Diazoxide; Drug Overdose; Female; Glucose Solution, Hypertonic; Humans; Hypoglycemia; Male; Manitoba | 1991 |