diazoxide has been researched along with Disease Models, Animal in 80 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our results suggested that diazoxide, which improved neurological deficits and decreased infarct volume and oxidative stress against ischemia-reperfusion injury, is mediated by spermine." | 7.80 | The effect of mitochondrial calcium uniporter opener spermine on diazoxide against focal cerebral ischemia--reperfusion injury in rats. ( Dong, H; Liu, Z; Wang, S; Yu, A; Zhang, Z, 2014) |
| "This study investigated the role of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain." | 7.79 | The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats. ( Afify, EA; Khedr, MM; Nasser, SA; Omar, AG, 2013) |
| "The neuroprotective effects of diazoxide against brain injury induced by deep hypothermia cerebral ischemia reperfusion through inhibiting oxygen free radicals and cell apoptosis." | 7.76 | [Effect of diazoxide on oxygen free radicals and cell apoptosis in brain tissue after deep hypothermia cerebral ischemia reperfusion injury in young rats]. ( Chen, F; Gu, HT; Gu, Q; He, XM; Mo, XM; Peng, W; Qi, JR; Sun, J; Zhang, YS, 2010) |
| "According to different treatment received before ischemic-reperfusion injury, 66 SD rats were divided into 6 groups including a normal control and a ischemia-reperfusion control group, IP10 group in which the rats received 10-min ischemia followed by 10-min interval for reperfusion for 3 times before IR, IP5 group in which the rats were subjected to 5-min ischemia with 5-min reperfusion intervals for 3 times before IR, adenosine (Ade) pretreatment group and diazoxide (Dia) pretreatment group." | 7.71 | Effect of pretreatment with adenosine, diazoxide or ischemic preconditioning on ischemia- reperfusion injury in the limbs of rats. ( Pei, GX; Wang, G; Wang, HM; Wang, QL, 2002) |
| "Spinal cord ischemia was induced by 4 minutes of thoracic aortic cross-clamp." | 5.51 | Pretreatment With Diazoxide Attenuates Spinal Cord Ischemia-Reperfusion Injury Through Signaling Transducer and Activator of Transcription 3 Pathway. ( Aftab, M; Cleveland, JC; Eldeiry, M; Fullerton, DA; Meng, X; Reece, TB; Roda, G; Ryan, TJ; Weyant, MJ; Yamanaka, K, 2019) |
| "Treatment with diazoxide partially normalizes obesity in children and adults with PWS and in a PWS mouse model, demonstrating that the biological pathways impacted by diazoxide may be rational pharmacological targets in PWS and other disorders diseases associated with obesity." | 5.48 | Chronic diazoxide treatment decreases fat mass and improves endurance capacity in an obese mouse model of Prader-Willi syndrome. ( Bischof, JM; Wevrick, R, 2018) |
| "Treatment with diazoxide can reduce necrosis of acinar cells in an experimental model of acute pancreatitis, but does not affect the inflammatory response or mortality after 72 h." | 5.46 | Effects of diazoxide in experimental acute necrotizing pancreatitis. ( de Oliveira Andrade, R; Koike, MK; Kunitake, T; Machado, MC; Souza, HP, 2017) |
| "DZX promoted the incidence of arrhythmias, because all DZX-treated T2DM hearts exhibited ischemia-induced VTs that persisted on reperfusion." | 5.42 | The Classically Cardioprotective Agent Diazoxide Elicits Arrhythmias in Type 2 Diabetes Mellitus. ( Akar, FG; Hu, J; Karam, BS; Motloch, LJ; Xie, C, 2015) |
| "To evaluate the effect of ATP-sensitive potassium channel openers cromakalim prodrug 1 (CKLP1) and diazoxide on IOP in three independent mouse models of ocular hypertension." | 4.12 | Effect of ATP-sensitive Potassium Channel Openers on Intraocular Pressure in Ocular Hypertensive Animal Models. ( Anderson, KJ; Dosa, PI; Fautsch, MP; Holman, BH; Millar, JC; Roddy, GW; Roy Chowdhury, U, 2022) |
| "The effects of diazoxide on cardiac hypertrophy and miR-132 expression were characterized in adult rats and in cardiomyocytes." | 3.88 | Protective Action of Diazoxide on Isoproterenol-Induced Hypertrophy Is Mediated by Reduction in MicroRNA-132 Expression. ( Carrillo, ED; García, MC; Hernández, A; Narasimhan, G; Sánchez, JA, 2018) |
| " This study was conducted to investigate whether or not triamterene, a K(+)-sparing diuretic, can generate protection against seizures induced by intravenous or intraperitoneal pentylenetetrazole (PTZ) models." | 3.83 | A role for ATP-sensitive potassium channels in the anticonvulsant effects of triamterene in mice. ( Almasirad, A; Barati, S; Ghasemi, M; Moezi, L; Shafaroodi, H, 2016) |
| "Our results suggested that diazoxide, which improved neurological deficits and decreased infarct volume and oxidative stress against ischemia-reperfusion injury, is mediated by spermine." | 3.80 | The effect of mitochondrial calcium uniporter opener spermine on diazoxide against focal cerebral ischemia--reperfusion injury in rats. ( Dong, H; Liu, Z; Wang, S; Yu, A; Zhang, Z, 2014) |
| "To investigate the effect of diazoxide administration on liver ischemia/reperfusion injury." | 3.80 | Beneficial effects of adenosine triphosphate-sensitive K+ channel opener on liver ischemia/reperfusion injury. ( Coelho, AM; D'Albuquerque, LA; Machado, MC; Nogueira, MA; Patzina, RA; Pinheiro da Silva, F; Sampietre, SN, 2014) |
| "This study investigated the role of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain." | 3.79 | The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats. ( Afify, EA; Khedr, MM; Nasser, SA; Omar, AG, 2013) |
| "The neuroprotective effects of diazoxide against brain injury induced by deep hypothermia cerebral ischemia reperfusion through inhibiting oxygen free radicals and cell apoptosis." | 3.76 | [Effect of diazoxide on oxygen free radicals and cell apoptosis in brain tissue after deep hypothermia cerebral ischemia reperfusion injury in young rats]. ( Chen, F; Gu, HT; Gu, Q; He, XM; Mo, XM; Peng, W; Qi, JR; Sun, J; Zhang, YS, 2010) |
| "Diazoxide is a putative mitochondrial, ATP-sensitive potassium channel opener that has been implicated in neuroprotection in cerebral ischemia." | 3.73 | Post-ischemic administration of diazoxide attenuates long-term microglial activation in the rat brain after permanent carotid artery occlusion. ( Bari, F; Domoki, F; Farkas, E; Luiten, PG; Mihály, A; Timmer, NM, 2005) |
| " We examined KATP channel modulation in renal ischemia-reperfusion injury (IRI), using an isolated perfused rat kidney (IPRK) model, in control, IRI, IRI+200 microM diazoxide (a KATP opener), IRI + 10 microM glibenclamide (a KATP blocker) and IRI + 200 microM diazoxide + 10 microM glibenclamide groups." | 3.72 | ATP-dependent K+ channels in renal ischemia reperfusion injury. ( Endre, ZH; Gobé, GC; Rahgozar, M; Willgoss, DA, 2003) |
| "According to different treatment received before ischemic-reperfusion injury, 66 SD rats were divided into 6 groups including a normal control and a ischemia-reperfusion control group, IP10 group in which the rats received 10-min ischemia followed by 10-min interval for reperfusion for 3 times before IR, IP5 group in which the rats were subjected to 5-min ischemia with 5-min reperfusion intervals for 3 times before IR, adenosine (Ade) pretreatment group and diazoxide (Dia) pretreatment group." | 3.71 | Effect of pretreatment with adenosine, diazoxide or ischemic preconditioning on ischemia- reperfusion injury in the limbs of rats. ( Pei, GX; Wang, G; Wang, HM; Wang, QL, 2002) |
| " We also examined body weight, hematology, blood pressure, heart rate, serum levels of testosterone and dihydrotestosterone, and glucose tolerance for a 4-month period." | 3.68 | The effects of topical diazoxide on hair follicular growth and physiology of the stumptailed macaque. ( Adachi, K; Cappas, A; Kamoda, H; Kemnitz, JW; Sakuma, A; Uno, H, 1990) |
| "Spinal cord ischemia was induced by a 4-min thoracic aortic cross-clamp." | 1.51 | Synergetic Induction of NGF With Diazoxide and Erythropoietin Attenuates Spinal Cord Ischemic Injury. ( Aftab, M; Eldeiry, M; Fullerton, DA; Meng, X; Reece, TB; Ryan, TJ; Weyant, MJ; Yamanaka, K, 2019) |
| "Spinal cord ischemia was induced by 4 minutes of thoracic aortic cross-clamp." | 1.51 | Pretreatment With Diazoxide Attenuates Spinal Cord Ischemia-Reperfusion Injury Through Signaling Transducer and Activator of Transcription 3 Pathway. ( Aftab, M; Cleveland, JC; Eldeiry, M; Fullerton, DA; Meng, X; Reece, TB; Roda, G; Ryan, TJ; Weyant, MJ; Yamanaka, K, 2019) |
| "Treatment with diazoxide partially normalizes obesity in children and adults with PWS and in a PWS mouse model, demonstrating that the biological pathways impacted by diazoxide may be rational pharmacological targets in PWS and other disorders diseases associated with obesity." | 1.48 | Chronic diazoxide treatment decreases fat mass and improves endurance capacity in an obese mouse model of Prader-Willi syndrome. ( Bischof, JM; Wevrick, R, 2018) |
| "Systemic inflammatory response syndrome is a complex pathophysiologic and immunologic response to an insult." | 1.48 | Anti-inflammatory effects of human embryonic stem cell-derived mesenchymal stem cells secretome preconditioned with diazoxide, trimetazidine and MG-132 on LPS-induced systemic inflammation mouse model. ( Eslami Far, A; Jahandideh, S; Kadivar, M; Khatami, S, 2018) |
| "Diazoxide is a drug used in the treatment of hypertension however, its effect on 5-hydroxyindole acetic acid (5-HIAA) and dopamine amines in adult animal models remains unclear." | 1.46 | Trace elements cause oxidative damage in the brain of rats with induced hypotension. ( Brizuela, NO; Guzmán, DC; Herrera, MO; Mejía, GB; Olguín, HJ; Peraza, AV, 2017) |
| "Treatment with diazoxide can reduce necrosis of acinar cells in an experimental model of acute pancreatitis, but does not affect the inflammatory response or mortality after 72 h." | 1.46 | Effects of diazoxide in experimental acute necrotizing pancreatitis. ( de Oliveira Andrade, R; Koike, MK; Kunitake, T; Machado, MC; Souza, HP, 2017) |
| "Diazoxide treatment attenuated the NMDA-induced hippocampal injury in rats, as demonstrated by decreases in the size of the lesion, neuronal loss and microglial reaction." | 1.43 | Diazoxide enhances excitotoxicity-induced neurogenesis and attenuates neurodegeneration in the rat non-neurogenic hippocampus. ( Andrade, C; Batlle, M; Gimeno-Bayón, J; Mahy, N; Martínez-Moreno, M; Ortega, FJ; Rodríguez, MJ, 2016) |
| "DZX promoted the incidence of arrhythmias, because all DZX-treated T2DM hearts exhibited ischemia-induced VTs that persisted on reperfusion." | 1.42 | The Classically Cardioprotective Agent Diazoxide Elicits Arrhythmias in Type 2 Diabetes Mellitus. ( Akar, FG; Hu, J; Karam, BS; Motloch, LJ; Xie, C, 2015) |
| "Treatment with diazoxide (a mitoKATP opener, 5 mg·kg·d) normalized the levels of protein thiols and reduced glutathione, rescued superoxide dismutase activity, and significantly prevented cardiac hypertrophy." | 1.42 | Mitochondrial ATP-sensitive potassium channel opening inhibits isoproterenol-induced cardiac hypertrophy by preventing oxidative damage. ( de Figueiredo Júnior, IL; Fernandes Facundo, Hd; Gomes Marques de Sousa, TA; Kowaltowski, AJ; Lemos Caldas, FR; Martins, PR; Rocha Leite, IM; Tavarez Filgueiras, AB, 2015) |
| "Pretreatment with diazoxide significantly reduced infarct volume and brain edema formation after ASDH." | 1.39 | The neuroprotective effect of diazoxide is mediated by mitochondrial ATP-dependent potassium channels in a rat model of acute subdural hematoma. ( Nakagawa, I; Nakase, H; Nishimura, F; Park, YS; Tamura, K; Wajima, D, 2013) |
| "IPC or ischemia was induced in rat retina in vivo." | 1.35 | Mitogen-activated protein kinase p38alpha and retinal ischemic preconditioning. ( Barone, FC; Dreixler, JC; Du, E; Roth, S; Shaikh, AR, 2009) |
| "Diazoxide (DZ) was used to decrease serum insulin and generate hyperglycemia." | 1.35 | Endothelial heparanase secretion after acute hypoinsulinemia is regulated by glucose and fatty acid. ( Abrahani, A; Deppe, S; Ghosh, S; Kewalramani, G; Kim, MS; Puthanveetil, P; Rodrigues, B; Wang, F, 2009) |
| "Diazoxide (5 mg/kg) were given 48 h before 20 min ischemia in the 48-h DZ group, whereas 15-min DZ group received diazoxide (5 mg/kg) 15 min before 20-min ischemia." | 1.35 | Delayed pharmacological pre-conditioning effect of mitochondrial ATP-sensitive potassium channel opener on neurologic injury in a rabbit model of spinal cord ischemia. ( Choe, G; Chung, SH; Kim, CS; Kim, KO, 2008) |
| "Diazoxide (DIAZ) has been shown to be neuroprotective in animal models of different brain pathologies." | 1.34 | Diazoxide is protective in the rat retina against ischemic injury induced by bilateral carotid occlusion and glutamate-induced degeneration. ( Atlasz, T; Babai, N; Bari, F; Domoki, F; Gabriel, R; Kiss, P; Reglodi, D; Tamas, A, 2007) |
| " Moreover, iptakalim and diazoxide reduced the enzymatic activities and mRNA levels of inducible nitric oxide synthase elicited by chronic administration of rotenone." | 1.33 | Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats. ( Ding, JH; Hu, G; Liu, SY; Liu, X; Long, Y; Sun, YH; Wang, F; Wang, H; Wu, J; Yang, Y; Yao, HH, 2005) |
| "Pretreatment with diazoxide significantly reduced the infarct volume from 6." | 1.33 | MitoKATP-channel opener protects against neuronal death in rat venous ischemia. ( Alessandri, B; Heimann, A; Kempski, O; Nakagawa, I, 2005) |
| "Diazoxide has been identified as a mitochondrial, ATP-dependent K(+) channel opener, and a potentially neuroprotective compound under ischemic conditions." | 1.33 | The effect of pre- and posttreatment with diazoxide on the early phase of chronic cerebral hypoperfusion in the rat. ( Bari, F; Domoki, F; Farkas, E; Institóris, A; Mihály, A, 2006) |
| "In order to study the cardioprotective effects of diazoxide on the myocardial ischemia/reperfusion injury of rats and mechanisms, the healthy SD rats were randomly divided into 2 groups: the rats in the experimental group were injected with diazoxide for preconditioning with the dosage of 12." | 1.33 | Cardioprotective effects of diazoxide on myocardial ischemia/reperfusion injury in rats. ( Hu, Z; Yang, Y; Zhang, K; Zhao, J, 2006) |
| " Studies also found that iptakalim and diazoxide could reduce the enzymic activities and mRNA levels of inducible nitric oxide synthase elicited by chronic administration of rotenone." | 1.33 | Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats. ( Ding, JH; Hu, G; Liu, SY; Liu, X; Long, Y; Sun, YH; Wang, F; Wang, H; Wu, J; Yang, Y; Yao, HH, 2006) |
| " Therefore, pharmacological preconditioning with diazoxide in combination with adenosine and a nitric oxide donor (triple-combination pharmacological preconditioning) may enhance cardioprotection." | 1.32 | Integrated pharmacological preconditioning in combination with adenosine, a mitochondrial KATP channel opener and a nitric oxide donor. ( Imamura, H; Kido, M; Nakao, S; Ninomiya, H; Okada, T; Otani, H; Shingu, K; Uchiyama, T; Uchiyama, Y, 2003) |
| "Psammomys obesus is a model of type 2 diabetes that displays resistance to insulin and deranged beta-cell response to glucose." | 1.31 | Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes. ( Cerasi, E; Efendic, S; Kaiser, N; Khan, A; Nesher, R; Warwar, N, 2001) |
| "Pretreatment with diazoxide (10 mg." | 1.29 | Effects of diazoxide on norepinephrine-induced vasocontraction and ischemic myocardium in rats. ( Ichihara, K; Nakai, T, 1994) |
| "In five patients with islet cell tumors and fasting hypoglycemia, basal proinsulin-like component ranged from 26 to 79% of the total immunoreactive insulin." | 1.25 | Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors. ( Gorden, P; Roth, J; Sherman, B, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (6.25) | 18.7374 |
| 1990's | 5 (6.25) | 18.2507 |
| 2000's | 32 (40.00) | 29.6817 |
| 2010's | 36 (45.00) | 24.3611 |
| 2020's | 2 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Roy Chowdhury, U | 1 |
| Millar, JC | 1 |
| Holman, BH | 1 |
| Anderson, KJ | 1 |
| Dosa, PI | 1 |
| Roddy, GW | 1 |
| Fautsch, MP | 1 |
| Haapanen, HJ | 1 |
| Arvola, O | 1 |
| Herajärvi, J | 2 |
| Anttila, T | 2 |
| Tuominen, H | 2 |
| Puistola, U | 1 |
| Karihtala, P | 1 |
| Kiviluoma, K | 1 |
| Juvonen, T | 2 |
| Anttila, V | 2 |
| Sarja, HE | 1 |
| Mustonen, C | 1 |
| Honkanen, HP | 1 |
| Haapanen, H | 1 |
| Miinalainen, I | 1 |
| Guzmán, DC | 1 |
| Herrera, MO | 1 |
| Brizuela, NO | 1 |
| Mejía, GB | 1 |
| Olguín, HJ | 1 |
| Peraza, AV | 1 |
| Santoro, A | 1 |
| Anjomani Virmouni, S | 1 |
| Paradies, E | 1 |
| Villalobos Coa, VL | 1 |
| Al-Mahdawi, S | 1 |
| Khoo, M | 1 |
| Porcelli, V | 1 |
| Vozza, A | 1 |
| Perrone, M | 1 |
| Denora, N | 1 |
| Taroni, F | 1 |
| Merla, G | 1 |
| Palmieri, L | 1 |
| Pook, MA | 1 |
| Marobbio, CMT | 1 |
| Bischof, JM | 1 |
| Wevrick, R | 1 |
| Fernandes de Mattos Dourado, S | 1 |
| Barbeiro, DF | 1 |
| Koike, MK | 2 |
| Barbeiro, HV | 1 |
| Pinheiro da Silva, F | 2 |
| César Machado, MC | 1 |
| Makepeace, CM | 2 |
| Suarez-Pierre, A | 1 |
| Kanter, EM | 1 |
| Schuessler, RB | 2 |
| Nichols, CG | 2 |
| Lawton, JS | 2 |
| Jahandideh, S | 1 |
| Khatami, S | 1 |
| Eslami Far, A | 1 |
| Kadivar, M | 1 |
| Yamanaka, K | 2 |
| Eldeiry, M | 2 |
| Aftab, M | 2 |
| Ryan, TJ | 2 |
| Roda, G | 1 |
| Meng, X | 2 |
| Weyant, MJ | 2 |
| Cleveland, JC | 1 |
| Fullerton, DA | 2 |
| Reece, TB | 2 |
| Narasimhan, G | 1 |
| Carrillo, ED | 1 |
| Hernández, A | 1 |
| García, MC | 1 |
| Sánchez, JA | 1 |
| Dong, H | 1 |
| Wang, S | 1 |
| Zhang, Z | 1 |
| Yu, A | 1 |
| Liu, Z | 1 |
| Zhang, D | 1 |
| Wan, A | 1 |
| Chiu, AP | 1 |
| Wang, Y | 1 |
| Wang, F | 4 |
| Neumaier, K | 1 |
| Lal, N | 1 |
| Bround, MJ | 1 |
| Johnson, JD | 1 |
| Vlodavsky, I | 1 |
| Rodrigues, B | 2 |
| Luppi, P | 1 |
| Drain, P | 1 |
| Janjua, MB | 1 |
| Anastacio, MM | 1 |
| Nogueira, MA | 1 |
| Coelho, AM | 1 |
| Sampietre, SN | 1 |
| Patzina, RA | 1 |
| D'Albuquerque, LA | 1 |
| Machado, MC | 2 |
| Lemos Caldas, FR | 1 |
| Rocha Leite, IM | 1 |
| Tavarez Filgueiras, AB | 1 |
| de Figueiredo Júnior, IL | 1 |
| Gomes Marques de Sousa, TA | 1 |
| Martins, PR | 1 |
| Kowaltowski, AJ | 1 |
| Fernandes Facundo, Hd | 1 |
| Xie, C | 1 |
| Hu, J | 1 |
| Motloch, LJ | 1 |
| Karam, BS | 1 |
| Akar, FG | 1 |
| Shafaroodi, H | 1 |
| Barati, S | 1 |
| Ghasemi, M | 1 |
| Almasirad, A | 1 |
| Moezi, L | 1 |
| Liu, X | 3 |
| Duan, P | 1 |
| Hu, X | 1 |
| Li, R | 1 |
| Zhu, Q | 1 |
| Martínez-Moreno, M | 1 |
| Batlle, M | 1 |
| Ortega, FJ | 1 |
| Gimeno-Bayón, J | 2 |
| Andrade, C | 1 |
| Mahy, N | 2 |
| Rodríguez, MJ | 2 |
| Wu, H | 1 |
| Wang, P | 1 |
| Li, Y | 1 |
| Wu, M | 1 |
| Lin, J | 1 |
| Huang, Z | 1 |
| de Oliveira Andrade, R | 1 |
| Kunitake, T | 1 |
| Souza, HP | 1 |
| Yang, YJ | 1 |
| Zhang, S | 1 |
| Ding, JH | 3 |
| Zhou, F | 1 |
| Hu, G | 3 |
| Katakam, PV | 2 |
| Domoki, F | 4 |
| Snipes, JA | 1 |
| Busija, AR | 1 |
| Jarajapu, YP | 1 |
| Busija, DW | 2 |
| Kim, MS | 1 |
| Puthanveetil, P | 1 |
| Kewalramani, G | 1 |
| Deppe, S | 1 |
| Ghosh, S | 1 |
| Abrahani, A | 1 |
| Dreixler, JC | 1 |
| Barone, FC | 1 |
| Shaikh, AR | 1 |
| Du, E | 1 |
| Roth, S | 1 |
| Huang, CW | 1 |
| Wu, SN | 1 |
| Cheng, JT | 1 |
| Tsai, JJ | 1 |
| Huang, CC | 1 |
| Afzal, MR | 1 |
| Haider, HKh | 1 |
| Idris, NM | 2 |
| Jiang, S | 1 |
| Ahmed, RP | 2 |
| Ashraf, M | 2 |
| He, XM | 1 |
| Mo, XM | 1 |
| Gu, Q | 2 |
| Chen, F | 2 |
| Zhang, YS | 1 |
| Peng, W | 2 |
| Qi, JR | 1 |
| Gu, HT | 1 |
| Sun, J | 2 |
| Szabadfi, K | 1 |
| Mester, L | 1 |
| Reglodi, D | 2 |
| Kiss, P | 2 |
| Babai, N | 2 |
| Racz, B | 1 |
| Kovacs, K | 1 |
| Szabo, A | 1 |
| Tamas, A | 2 |
| Gabriel, R | 2 |
| Atlasz, T | 2 |
| Haider, KH | 1 |
| Kim, HW | 1 |
| Shujia, J | 1 |
| Liu, D | 2 |
| Pitta, M | 1 |
| Lee, JH | 1 |
| Ray, B | 1 |
| Lahiri, DK | 1 |
| Furukawa, K | 1 |
| Mughal, M | 1 |
| Jiang, H | 1 |
| Villarreal, J | 1 |
| Cutler, RG | 1 |
| Greig, NH | 1 |
| Mattson, MP | 2 |
| Vigneron, F | 1 |
| Dos Santos, P | 1 |
| Lemoine, S | 1 |
| Bonnet, M | 1 |
| Tariosse, L | 1 |
| Couffinhal, T | 1 |
| Duplaà, C | 1 |
| Jaspard-Vinassa, B | 1 |
| Nuñez, IP | 1 |
| Fantinelli, J | 1 |
| Arbeláez, LF | 1 |
| Mosca, SM | 1 |
| Virgili, N | 1 |
| Espinosa-Parrilla, JF | 1 |
| Mancera, P | 1 |
| Pastén-Zamorano, A | 1 |
| Pugliese, M | 1 |
| Ploug, KB | 1 |
| Amrutkar, DV | 1 |
| Baun, M | 1 |
| Ramachandran, R | 1 |
| Iversen, A | 1 |
| Lund, TM | 1 |
| Gupta, S | 1 |
| Hay-Schmidt, A | 1 |
| Olesen, J | 1 |
| Jansen-Olesen, I | 1 |
| Afify, EA | 1 |
| Khedr, MM | 1 |
| Omar, AG | 1 |
| Nasser, SA | 1 |
| Nakagawa, I | 2 |
| Wajima, D | 1 |
| Tamura, K | 1 |
| Nishimura, F | 1 |
| Park, YS | 1 |
| Nakase, H | 1 |
| Wang, QL | 1 |
| Wang, G | 1 |
| Wang, HM | 1 |
| Pei, GX | 1 |
| Uchiyama, Y | 1 |
| Otani, H | 1 |
| Okada, T | 1 |
| Uchiyama, T | 1 |
| Ninomiya, H | 1 |
| Kido, M | 1 |
| Imamura, H | 1 |
| Nakao, S | 1 |
| Shingu, K | 1 |
| Slevin, JR | 1 |
| Lu, C | 1 |
| Chan, SL | 1 |
| Hansson, M | 1 |
| Elmér, E | 1 |
| Duncker, DJ | 1 |
| Verdouw, PD | 1 |
| McCully, JD | 3 |
| Levitsky, S | 3 |
| Rahgozar, M | 1 |
| Willgoss, DA | 1 |
| Gobé, GC | 1 |
| Endre, ZH | 1 |
| Jiang, K | 1 |
| Zhao, Z | 1 |
| Shui, Q | 1 |
| Xia, Z | 1 |
| Yang, Y | 3 |
| Long, Y | 2 |
| Liu, SY | 2 |
| Sun, YH | 2 |
| Yao, HH | 2 |
| Wang, H | 2 |
| Wu, J | 2 |
| Pompermayer, K | 1 |
| Souza, DG | 1 |
| Lara, GG | 1 |
| Silveira, KD | 1 |
| Cassali, GD | 1 |
| Andrade, AA | 1 |
| Bonjardim, CA | 1 |
| Passaglio, KT | 1 |
| Assreuy, J | 1 |
| Cunha, FQ | 1 |
| Vieira, MA | 1 |
| Teixeira, MM | 1 |
| Farkas, E | 2 |
| Timmer, NM | 1 |
| Mihály, A | 2 |
| Luiten, PG | 1 |
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| Zhao, J | 1 |
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2 reviews available for diazoxide and Disease Models, Animal
| Article | Year |
|---|---|
Novel neuroprotective strategies in ischemic retinal lesions.
Topics: Animals; Benzimidazoles; Diazoxide; Disease Models, Animal; Ischemia; Neuroprotective Agents; Pituit | 2010 |
Mitochondrial ATP-sensitive potassium channels in surgical cardioprotection.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cardiotonic Agents; Diazoxide; Disease Models, Animal; H | 2003 |
78 other studies available for diazoxide and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Effect of ATP-sensitive Potassium Channel Openers on Intraocular Pressure in Ocular Hypertensive Animal Models.
Topics: Animals; Antihypertensive Agents; Cromakalim; Diazoxide; Disease Models, Animal; Eye; Intraocular Pr | 2022 |
Pharmacological Preconditioning with Diazoxide in the Experimental Hypothermic Circulatory Arrest Model.
Topics: Animals; Brain Ischemia; Circulatory Arrest, Deep Hypothermia Induced; Diazoxide; Disease Models, An | 2017 |
Diazoxide Attenuates Ischemic Myocardial Injury in a Porcine Model.
Topics: Animals; Diazoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Infusions, Int | 2017 |
Trace elements cause oxidative damage in the brain of rats with induced hypotension.
Topics: Adenosine Triphosphatases; Animals; Antihypertensive Agents; Brain; Diazoxide; Disease Models, Anima | 2017 |
Effect of diazoxide on Friedreich ataxia models.
Topics: Animals; Cell Line; Cells, Cultured; Diazoxide; Disease Models, Animal; Frataxin; Friedreich Ataxia; | 2018 |
Chronic diazoxide treatment decreases fat mass and improves endurance capacity in an obese mouse model of Prader-Willi syndrome.
Topics: Animals; Antigens, Neoplasm; Antihypertensive Agents; Body Fat Distribution; Diazoxide; Diet, High-F | 2018 |
Diazoxide reduces local and remote organ damage in a rat model of intestinal ischemia reperfusion.
Topics: Animals; Aspartate Aminotransferases; Cyclooxygenase 2; Diazoxide; Disease Models, Animal; Heart; Hu | 2018 |
Superior diastolic function with K
Topics: Animals; Cardiotonic Agents; Coronary Vessels; Diastole; Diazoxide; Disease Models, Animal; Heart; H | 2018 |
Anti-inflammatory effects of human embryonic stem cell-derived mesenchymal stem cells secretome preconditioned with diazoxide, trimetazidine and MG-132 on LPS-induced systemic inflammation mouse model.
Topics: Animals; Cell Line; Culture Media, Conditioned; Cytokines; Diazoxide; Disease Models, Animal; Human | 2018 |
Pretreatment With Diazoxide Attenuates Spinal Cord Ischemia-Reperfusion Injury Through Signaling Transducer and Activator of Transcription 3 Pathway.
Topics: Administration, Oral; Animals; Blotting, Western; Diazoxide; Disease Models, Animal; Male; Mice; Mic | 2019 |
Protective Action of Diazoxide on Isoproterenol-Induced Hypertrophy Is Mediated by Reduction in MicroRNA-132 Expression.
Topics: Animals; Animals, Newborn; Cardiomegaly; Cardiovascular Agents; Cells, Cultured; Cyclic AMP Response | 2018 |
Synergetic Induction of NGF With Diazoxide and Erythropoietin Attenuates Spinal Cord Ischemic Injury.
Topics: Animals; Aortic Aneurysm, Thoracic; Diazoxide; Disease Models, Animal; Drug Synergism; Erythropoieti | 2019 |
The effect of mitochondrial calcium uniporter opener spermine on diazoxide against focal cerebral ischemia--reperfusion injury in rats.
Topics: Animals; Behavior, Animal; Brain; Calcium Channels; Cerebral Infarction; Cytoprotection; Diazoxide; | 2014 |
Hyperglycemia-induced secretion of endothelial heparanase stimulates a vascular endothelial growth factor autocrine network in cardiomyocytes that promotes recruitment of lipoprotein lipase.
Topics: AMP-Activated Protein Kinases; Animals; Autocrine Communication; Blood Glucose; Calcium; Coronary Ve | 2013 |
Autocrine C-peptide mechanism underlying INS1 beta cell adaptation to oxidative stress.
Topics: Adaptation, Physiological; Animals; Apoptosis; Autocrine Communication; C-Peptide; Cell Line, Tumor; | 2014 |
Cardioprotective benefits of adenosine triphosphate-sensitive potassium channel opener diazoxide are lost with administration after the onset of stress in mouse and human myocytes.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Diazoxide; Disease Models, Animal; Female; Heart A | 2014 |
Beneficial effects of adenosine triphosphate-sensitive K+ channel opener on liver ischemia/reperfusion injury.
Topics: Animals; Biomarkers; Diazoxide; Disease Models, Animal; Inflammation; Inflammation Mediators; Liver; | 2014 |
Mitochondrial ATP-sensitive potassium channel opening inhibits isoproterenol-induced cardiac hypertrophy by preventing oxidative damage.
Topics: Animals; Antioxidants; Cardiomegaly; Cardiotonic Agents; Diazoxide; Disease Models, Animal; Mice; Mi | 2015 |
The Classically Cardioprotective Agent Diazoxide Elicits Arrhythmias in Type 2 Diabetes Mellitus.
Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Diabetes Mellitus, Type 2; Diazoxide; Disease Mod | 2015 |
A role for ATP-sensitive potassium channels in the anticonvulsant effects of triamterene in mice.
Topics: Analysis of Variance; Animals; Anticonvulsants; Convulsants; Diazoxide; Disease Models, Animal; Dose | 2016 |
Altered KATP Channel Subunits Expression and Vascular Reactivity in Spontaneously Hypertensive Rats With Age.
Topics: Age Factors; Aging; Animals; Aorta; Blood Pressure; Diazoxide; Disease Models, Animal; Dose-Response | 2016 |
Diazoxide enhances excitotoxicity-induced neurogenesis and attenuates neurodegeneration in the rat non-neurogenic hippocampus.
Topics: Administration, Oral; Animals; Astrocytes; Diazoxide; Disease Models, Animal; Doublecortin Protein; | 2016 |
Diazoxide Attenuates Postresuscitation Brain Injury in a Rat Model of Asphyxial Cardiac Arrest by Opening Mitochondrial ATP-Sensitive Potassium Channels.
Topics: Animals; Asphyxia; Brain Injuries; Cerebral Cortex; Diazoxide; Disease Models, Animal; Heart Arrest; | 2016 |
Effects of diazoxide in experimental acute necrotizing pancreatitis.
Topics: Animals; Cholagogues and Choleretics; Diazoxide; Disease Models, Animal; Male; Pancreatitis, Acute N | 2017 |
Iptakalim protects against MPP+-induced degeneration of dopaminergic neurons in association with astrocyte activation.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Brain Stem | 2009 |
Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance.
Topics: Animals; Cerebral Arteries; Cyclooxygenase Inhibitors; Diazoxide; Disease Models, Animal; Dose-Respo | 2009 |
Endothelial heparanase secretion after acute hypoinsulinemia is regulated by glucose and fatty acid.
Topics: Animals; Cattle; Cells, Cultured; Cytochalasin D; Cytoskeleton; Diazoxide; Disease Models, Animal; E | 2009 |
Mitogen-activated protein kinase p38alpha and retinal ischemic preconditioning.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Anisomycin; Diazoxide | 2009 |
Diazoxide reduces status epilepticus neuron damage in diabetes.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Blood Glucose; Cell Line, Transformed; Diabet | 2010 |
Preconditioning promotes survival and angiomyogenic potential of mesenchymal stem cells in the infarcted heart via NF-kappaB signaling.
Topics: Androstadienes; Animals; Cell Survival; Diazoxide; Disease Models, Animal; Echocardiography; Female; | 2010 |
[Effect of diazoxide on oxygen free radicals and cell apoptosis in brain tissue after deep hypothermia cerebral ischemia reperfusion injury in young rats].
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Caspase 3; Circulatory Arrest, Deep Hypothermia Induced; | 2010 |
MicroRNA-21 is a key determinant in IL-11/Stat3 anti-apoptotic signalling pathway in preconditioning of skeletal myoblasts.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Survival; Cells, Cultured; Diazoxide; Disease Models, | 2010 |
The KATP channel activator diazoxide ameliorates amyloid-β and tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Anim | 2010 |
GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Cell Cycle Proteins; Diazoxide; Dis | 2011 |
Mitochondrial KATP channels participate in the limitation of infarct size by cariporide.
Topics: Animals; Calcium; Cardiotonic Agents; Decanoic Acids; Diazoxide; Disease Models, Animal; Guanidines; | 2011 |
Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Cell Line; Diazoxi | 2011 |
K(ATP) channel openers in the trigeminovascular system.
Topics: Animals; ATP-Binding Cassette Transporters; Calcitonin Gene-Related Peptide; Cell Degranulation; Cro | 2012 |
The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats.
Topics: Acute Pain; Analgesics, Opioid; Animals; Chemical and Drug Induced Liver Injury; Diazoxide; Disease | 2013 |
The neuroprotective effect of diazoxide is mediated by mitochondrial ATP-dependent potassium channels in a rat model of acute subdural hematoma.
Topics: Animals; Brain Infarction; Decanoic Acids; Diazoxide; Disease Models, Animal; Hematoma, Subdural, Ac | 2013 |
Effect of pretreatment with adenosine, diazoxide or ischemic preconditioning on ischemia- reperfusion injury in the limbs of rats.
Topics: Adenosine; Animals; Creatine Kinase; Diazoxide; Disease Models, Animal; Extremities; Ischemic Precon | 2002 |
Integrated pharmacological preconditioning in combination with adenosine, a mitochondrial KATP channel opener and a nitric oxide donor.
Topics: Adenosine; Animals; Combined Modality Therapy; Coronary Circulation; Creatine Kinase; Diazoxide; Dis | 2003 |
Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death.
Topics: Animals; Apoptosis; Brain Ischemia; Cell Death; Cell Hypoxia; Cells, Cultured; Cyanides; Decanoic Ac | 2003 |
Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice.
Topics: Adenosine Triphosphate; Animals; Cardiotonic Agents; Diazoxide; Disease Models, Animal; Dose-Respons | 2003 |
ATP-dependent K+ channels in renal ischemia reperfusion injury.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Cromakalim; Diazoxide; Disease Models, Animal; | 2003 |
Electro-acupuncture preconditioning abrogates the elevation of c-Fos and c-Jun expression in neonatal hypoxic-ischemic rat brains induced by glibenclamide, an ATP-sensitive potassium channel blocker.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Blotting, Western; Brain; Diazoxide; Disease Mod | 2004 |
Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Basal Ganglia; Brain; Brain Chem | 2005 |
The ATP-sensitive potassium channel blocker glibenclamide prevents renal ischemia/reperfusion injury in rats.
Topics: Adenosine Triphosphate; Animals; Cytokines; Diazoxide; Disease Models, Animal; Glyburide; Interleuki | 2005 |
Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats.
Topics: Animals; Antiparkinson Agents; Basal Ganglia; Catalepsy; Decanoic Acids; Diazoxide; Disease Models, | 2006 |
Post-ischemic administration of diazoxide attenuates long-term microglial activation in the rat brain after permanent carotid artery occlusion.
Topics: Animals; Brain Infarction; Brain Ischemia; Carotid Stenosis; CD11 Antigens; Cerebrovascular Circulat | 2005 |
MitoKATP-channel opener protects against neuronal death in rat venous ischemia.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Brain Edema; Brain Infarction; Cell Death; Ce | 2005 |
Multiple treatment approach to limit cardiac ischemia-reperfusion injury.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Combined Modality Therapy; Diazoxide; | 2005 |
Invited commentary.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Combined Modality Therapy; Diazoxide; | 2005 |
The effect of pre- and posttreatment with diazoxide on the early phase of chronic cerebral hypoperfusion in the rat.
Topics: Animals; Antihypertensive Agents; Behavior, Animal; Brain Ischemia; Cell Survival; Diazoxide; Diseas | 2006 |
Cardioprotective effects of diazoxide on myocardial ischemia/reperfusion injury in rats.
Topics: Animals; Cardiotonic Agents; Diazoxide; Disease Models, Animal; Ischemic Preconditioning; Male; Myoc | 2006 |
Systemic administration of diazoxide induces delayed preconditioning against transient focal cerebral ischemia in rats.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Cerebral Infarction; Decanoic Acids; Diazoxid | 2007 |
Cardioplegia and diazoxide modulate STAT3 activation and DNA binding.
Topics: Animals; Apoptosis; Binding Sites; Blotting, Western; Cardioplegic Solutions; Diazoxide; Disease Mod | 2007 |
Diazoxide is protective in the rat retina against ischemic injury induced by bilateral carotid occlusion and glutamate-induced degeneration.
Topics: Animals; Animals, Newborn; Cell Count; Diazoxide; Disease Models, Animal; Drug Interactions; Glutami | 2007 |
Delayed pharmacological pre-conditioning effect of mitochondrial ATP-sensitive potassium channel opener on neurologic injury in a rabbit model of spinal cord ischemia.
Topics: Analgesics; Animals; Blood Gas Analysis; Diazoxide; Disease Models, Animal; Ischemic Preconditioning | 2008 |
Neuroprotective effect of diazoxide on brain injury induced by cerebral ischemia/reperfusion during deep hypothermia.
Topics: Analysis of Variance; Animals; Brain Injuries; Caspase 3; Cerebrovascular Circulation; Cytochromes c | 2008 |
Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats.
Topics: Animals; Arginine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Diazoxide; Disease Mode | 2008 |
Diazoxide increases liver and kidney HSP25 and HSP70 after shock and stroke.
Topics: Animals; Diazoxide; Disease Models, Animal; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 He | 2008 |
Brief femoral artery ischaemia provides protection against myocardial ischaemia-reperfusion injury in rats: the possible mechanisms.
Topics: Animals; Arginine; Blood Pressure; Creatine Kinase, MB Form; Diazoxide; Disease Models, Animal; Femo | 2008 |
Effect of pressure overload on cardioprotection of mitochondrial KATP channels and GSK-3beta: interaction with the MPT pore.
Topics: Animals; Cardiotonic Agents; Cyclosporine; Diazoxide; Disease Models, Animal; Glyburide; Glycogen Sy | 2008 |
Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart.
Topics: 8,11,14-Eicosatrienoic Acid; Adamantane; Animals; Blood Pressure; Cardiovascular Agents; Coronary Ci | 2008 |
Prophylaxis of genetically determined diabetes by diazoxide: a study in a rat model of naturally occurring obese diabetes.
Topics: Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diazoxide; Di | 1995 |
Effects of diazoxide on norepinephrine-induced vasocontraction and ischemic myocardium in rats.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Calcium; Diazoxide; Disease Models, Animal; Dose-Res | 1994 |
Modulation of GABA transmission by diazoxide and cromakalim in the globus pallidus: implications for the treatment of Parkinson's disease.
Topics: Animals; Antihypertensive Agents; Behavior, Animal; Benzopyrans; Cromakalim; Diazoxide; Disease Mode | 1996 |
Microvascular permeability with sulfonylureas in normal and diabetic hamsters.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Capillary Permeability; Cricetinae; Dextrans; D | 1997 |
Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.
Topics: Animals; Colforsin; Diabetes Mellitus, Type 2; Diazoxide; Disease Models, Animal; Disease Susceptibi | 2001 |
Opening of mitochondrial ATP-sensitive potassium channels enhances cardioplegic protection.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cardioplegic Solutions; Diazoxide; Disease Mo | 2001 |
Long-term function of isotransplanted islets of Langerhans in the diabetic rat.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus; Diazoxide; Disease Models, Animal; | 1976 |
Studies of plasma renin activity in coarctation of the aorta.
Topics: Adolescent; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Child; Diazoxide; Disease | 1976 |
The effects of topical diazoxide on hair follicular growth and physiology of the stumptailed macaque.
Topics: Alopecia; Animals; Blood Pressure; Body Weight; Diazoxide; Dihydrotestosterone; Disease Models, Anim | 1990 |
Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Animals; Child; Chromatography, Gel; Cricetinae; | 1971 |
Alpha-adrenergic inhibition of immunoreactive insulin release during deep hypothermia.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Glucose; Blood Pressure; B | 1971 |
Hemodynamics of early experimental renal hypertension in dogs. Normal limb blood flow, elevated limb vascular resistance, and decreased venous compliance.
Topics: Animals; Blood Pressure; Blood Volume; Diazoxide; Disease Models, Animal; Dogs; Femoral Vein; Foreli | 1972 |