diazoxide has been researched along with Developmental Disabilities in 8 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Developmental Disabilities: Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Persistent hyperinsulinism was only described in two siblings and responded to diazoxide treatment." | 5.12 | Expanding the spectrum of endocrinopathies identified in Schaaf-Yang syndrome - A case report and review of the literature. ( Cohen, M; Ekhilevitch, N; Habib, C; Halloun, R; Tiosano, D; Weiss, R, 2021) |
| "Neonatal hypoglycemia is one of the most common biochemical abnormalities encountered in the newborn." | 2.50 | Update on neonatal hypoglycemia. ( Rozance, PJ, 2014) |
| "Diazoxide therapy was effective for the hypoglycemia." | 1.42 | Neonatal case of novel KMT2D mutation in Kabuki syndrome with severe hypoglycemia. ( Gohda, Y; Kondoh, T; Matsumoto, T; Matsunaga, T; Oka, S; Watanabe, S; Yoshiura, K, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Halloun, R | 1 |
| Habib, C | 1 |
| Ekhilevitch, N | 1 |
| Weiss, R | 1 |
| Tiosano, D | 1 |
| Cohen, M | 1 |
| Ağladıoğlu, SY | 1 |
| Savaş Erdeve, S | 1 |
| Cetinkaya, S | 1 |
| Baş, VN | 1 |
| Peltek Kendirci, HN | 1 |
| Onder, A | 1 |
| Aycan, Z | 1 |
| Rozance, PJ | 1 |
| Gohda, Y | 1 |
| Oka, S | 1 |
| Matsunaga, T | 1 |
| Watanabe, S | 1 |
| Yoshiura, K | 1 |
| Kondoh, T | 1 |
| Matsumoto, T | 1 |
| Levy-Shraga, Y | 1 |
| Pinhas-Hamiel, O | 1 |
| Kraus-Houminer, E | 1 |
| Landau, H | 1 |
| Mazor-Aronovitch, K | 1 |
| Modan-Moses, D | 1 |
| Gillis, D | 1 |
| Koren, I | 1 |
| Dollberg, D | 1 |
| Gabis, LV | 1 |
| Meissner, T | 1 |
| Wendel, U | 1 |
| Burgard, P | 1 |
| Schaetzle, S | 1 |
| Mayatepek, E | 1 |
| Menni, F | 1 |
| de Lonlay, P | 1 |
| Sevin, C | 1 |
| Touati, G | 1 |
| Peigné, C | 1 |
| Barbier, V | 1 |
| Nihoul-Fékété, C | 1 |
| Saudubray, JM | 1 |
| Robert, JJ | 1 |
| Gottschalk, ME | 1 |
| Geffner, ME | 1 |
| Yasuda, PM | 1 |
| Shields, WD | 1 |
2 reviews available for diazoxide and Developmental Disabilities
| Article | Year |
|---|---|
Expanding the spectrum of endocrinopathies identified in Schaaf-Yang syndrome - A case report and review of the literature.
Topics: Developmental Disabilities; Diazoxide; Female; Humans; Hyperinsulinism; Infant; Insulin; Mutation; P | 2021 |
Update on neonatal hypoglycemia.
Topics: Biosensing Techniques; Blood Glucose; Developmental Disabilities; Diazoxide; Diuretics; Female; Gluc | 2014 |
6 other studies available for diazoxide and Developmental Disabilities
| Article | Year |
|---|---|
Hyperinsulinemic hypoglycemia: experience in a series of 17 cases.
Topics: Child; Child, Preschool; Developmental Disabilities; Diazoxide; Epilepsy; Female; Humans; Hyperinsul | 2013 |
Neonatal case of novel KMT2D mutation in Kabuki syndrome with severe hypoglycemia.
Topics: Abnormalities, Multiple; Blood Glucose; Congenital Hyperinsulinism; Developmental Disabilities; Diaz | 2015 |
Cognitive and developmental outcome of conservatively treated children with congenital hyperinsulinism.
Topics: Adaptation, Psychological; Antihypertensive Agents; Child; Child Behavior; Child Development; Child, | 2013 |
Long-term follow-up of 114 patients with congenital hyperinsulinism.
Topics: Adolescent; Age of Onset; Child; Child, Preschool; Developmental Disabilities; Diabetes Mellitus, Ty | 2003 |
Neurologic outcomes of 90 neonates and infants with persistent hyperinsulinemic hypoglycemia.
Topics: Age of Onset; Child; Child, Preschool; Developmental Disabilities; Diazoxide; Epilepsy; Humans; Hype | 2001 |
Reversal of microcephaly and developmental delay after cure of hyperinsulinemic hypoglycemia.
Topics: Blood Glucose; Child, Preschool; Developmental Disabilities; Diazoxide; Female; Humans; Hypoglycemia | 1990 |