diazoxide has been researched along with Degenerative Diseases, Central Nervous System in 2 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Excerpt | Relevance | Reference |
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"Diazoxide treatment attenuated the NMDA-induced hippocampal injury in rats, as demonstrated by decreases in the size of the lesion, neuronal loss and microglial reaction." | 1.43 | Diazoxide enhances excitotoxicity-induced neurogenesis and attenuates neurodegeneration in the rat non-neurogenic hippocampus. ( Andrade, C; Batlle, M; Gimeno-Bayón, J; Mahy, N; Martínez-Moreno, M; Ortega, FJ; Rodríguez, MJ, 2016) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Virgili, N | 1 |
Mancera, P | 1 |
Wappenhans, B | 1 |
Sorrosal, G | 1 |
Biber, K | 1 |
Pugliese, M | 1 |
Espinosa-Parrilla, JF | 1 |
Martínez-Moreno, M | 1 |
Batlle, M | 1 |
Ortega, FJ | 1 |
Gimeno-Bayón, J | 1 |
Andrade, C | 1 |
Mahy, N | 1 |
Rodríguez, MJ | 1 |
2 other studies available for diazoxide and Degenerative Diseases, Central Nervous System
Article | Year |
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K(ATP) channel opener diazoxide prevents neurodegeneration: a new mechanism of action via antioxidative pathway activation.
Topics: Animals; Antioxidants; Cell Line; Cell Survival; Cerebellum; Diazoxide; Dose-Response Relationship, | 2013 |
Diazoxide enhances excitotoxicity-induced neurogenesis and attenuates neurodegeneration in the rat non-neurogenic hippocampus.
Topics: Administration, Oral; Animals; Astrocytes; Diazoxide; Disease Models, Animal; Doublecortin Protein; | 2016 |