diazoxide has been researched along with Cystic Fibrosis in 2 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chung, WJ | 1 |
Goeckeler-Fried, JL | 1 |
Havasi, V | 1 |
Chiang, A | 1 |
Rowe, SM | 1 |
Plyler, ZE | 1 |
Hong, JS | 1 |
Mazur, M | 1 |
Piazza, GA | 1 |
Keeton, AB | 1 |
White, EL | 1 |
Rasmussen, L | 1 |
Weissman, AM | 1 |
Denny, RA | 1 |
Brodsky, JL | 1 |
Sorscher, EJ | 1 |
Hongre, AS | 1 |
BarĂ³, I | 1 |
Berthon, B | 1 |
Escande, D | 1 |
2 other studies available for diazoxide and Cystic Fibrosis
Article | Year |
---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regu | 2016 |
Effects of sulphonylureas on cAMP-stimulated Cl- transport via the cystic fibrosis gene product in human epithelial cells.
Topics: Adenosine Triphosphate; Blood Proteins; Cell Line; Chloride Channels; Colforsin; Cyclic AMP; Cystic | 1994 |