diazoxide has been researched along with Coronary Artery Disease in 3 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Representative blood samples for hyaluronan and syndecan-1, before, during and after surgery, were obtained in 13 out of 16 patients that had a history of stable coronary artery disease undergoing CABG with or without diazoxide." | 5.16 | Diazoxide may protect endothelial glycocalyx integrity during coronary artery bypass grafting. ( Hämäläinen, M; Huovinen, S; Leppänen, T; Mennander, AA; Moilanen, E; Oksala, N; Shalaby, A; Tarkka, M; Zhao, F, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deja, MA | 1 |
| Malinowski, M | 1 |
| Gołba, KS | 1 |
| Kajor, M | 1 |
| Lebda-Wyborny, T | 1 |
| Hudziak, D | 1 |
| Domaradzki, W | 1 |
| Szurlej, D | 1 |
| Bończyk, A | 1 |
| Biernat, J | 1 |
| Woś, S | 1 |
| Shalaby, A | 2 |
| Mennander, A | 1 |
| Rinne, T | 1 |
| Oksala, N | 2 |
| Aanismaa, R | 1 |
| Narkilahti, S | 1 |
| Paavonen, T | 1 |
| Laurikka, J | 1 |
| Tarkka, M | 2 |
| Mennander, AA | 1 |
| Leppänen, T | 1 |
| Hämäläinen, M | 1 |
| Huovinen, S | 1 |
| Zhao, F | 1 |
| Moilanen, E | 1 |
3 trials available for diazoxide and Coronary Artery Disease
| Article | Year |
|---|---|
Diazoxide protects myocardial mitochondria, metabolism, and function during cardiac surgery: a double-blind randomized feasibility study of diazoxide-supplemented cardioplegia.
Topics: Aged; Cardioplegic Solutions; Cardiovascular Agents; Coronary Artery Bypass; Coronary Artery Disease | 2009 |
Aquaporin-7 expression during coronary artery bypass grafting with diazoxide.
Topics: Aquaporins; Biopsy; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Artery Disease; Diazoxi | 2011 |
Diazoxide may protect endothelial glycocalyx integrity during coronary artery bypass grafting.
Topics: Biomarkers; Biopsy; Coronary Artery Bypass; Coronary Artery Disease; Diazoxide; Double-Blind Method; | 2012 |