diazoxide has been researched along with Coma, Hyperglycemic Hyperosmolar Nonketotic in 3 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperosmolar coma with ketoacidosis is a rare side-effect of diazoxide therapy, documented even in patients with persistent hyperinsulinemic hypoglycemia of infancy." | 1.48 | Diazoxide toxicity in a child with persistent hyperinsulinemic hypoglycemia of infancy: mixed hyperglycemic hyperosmolar coma and ketoacidosis. ( Bhatia, V; Ellard, S; Flanagan, SE; Hussain, K; Mangla, P, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Boudreau, LE | 1 |
| Padbury, JF | 1 |
| Mangla, P | 1 |
| Hussain, K | 1 |
| Ellard, S | 1 |
| Flanagan, SE | 1 |
| Bhatia, V | 1 |
| Savage, JM | 1 |
| Slattery, C | 1 |
3 other studies available for diazoxide and Coma, Hyperglycemic Hyperosmolar Nonketotic
| Article | Year |
|---|---|
50 Years Ago in TheJournalofPediatrics: Diazoxide-Induced Hyperosmolar Nonketotic Coma: Contemporary Genetic Insights.
Topics: Child; Diazoxide; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Hyperinsulinism | 2021 |
Diazoxide toxicity in a child with persistent hyperinsulinemic hypoglycemia of infancy: mixed hyperglycemic hyperosmolar coma and ketoacidosis.
Topics: Antihypertensive Agents; Congenital Hyperinsulinism; Diazoxide; Humans; Hyperglycemic Hyperosmolar N | 2018 |
Hyperosmolar non-ketotic hyperglycaemia during oral diazoxide therapy of prolonged hyperglycaemia in infancy.
Topics: Age Factors; Diabetic Coma; Diazoxide; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Hyperinsu | 1977 |