diazoxide has been researched along with Cerebral Infarction, Middle Cerebral Artery in 6 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazoxide and spermine were administrated 30 minutes before ischemia or 10 minutes before reperfusion, respectively." | 1.40 | Spermine attenuates the preconditioning of diazoxide against transient focal cerebral ischemia in rats. ( Dong, H; Guo, Y; Li, S; Li, Y; Wang, P; Wang, S; Yao, R; Zhang, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 1 |
| Wang, S | 1 |
| Dong, H | 1 |
| Li, Y | 1 |
| Wang, P | 1 |
| Li, S | 1 |
| Guo, Y | 1 |
| Yao, R | 1 |
| Rutkai, I | 1 |
| Katakam, PV | 1 |
| Dutta, S | 1 |
| Busija, DW | 2 |
| Abe, E | 1 |
| Fujiki, M | 1 |
| Nagai, Y | 1 |
| Shiqi, K | 1 |
| Kubo, T | 1 |
| Ishii, K | 1 |
| Abe, T | 1 |
| Kobayashi, H | 1 |
| Shimizu, K | 1 |
| Lacza, Z | 1 |
| Rajapakse, N | 1 |
| Horiguchi, T | 1 |
| Snipes, J | 1 |
| Wu, L | 1 |
| Shen, F | 1 |
| Lin, L | 1 |
| Zhang, X | 1 |
| Bruce, IC | 1 |
| Xia, Q | 1 |
| Liu, D | 1 |
| Lu, C | 1 |
| Wan, R | 1 |
| Auyeung, WW | 1 |
| Mattson, MP | 1 |
6 other studies available for diazoxide and Cerebral Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Spermine attenuates the preconditioning of diazoxide against transient focal cerebral ischemia in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Calcium Channels; Cytochromes c; Diazoxide; I | 2014 |
Sustained mitochondrial functioning in cerebral arteries after transient ischemic stress in the rat: a potential target for therapies.
Topics: Acetylcholine; Animals; Bradykinin; Cerebral Arteries; Diazoxide; Infarction, Middle Cerebral Artery | 2014 |
The phosphatidylinositol-3 kinase/Akt pathway mediates geranylgeranylacetone-induced neuroprotection against cerebral infarction in rats.
Topics: Androstadienes; Animals; Brain; Brain Infarction; Central Nervous System Agents; Decanoic Acids; Dia | 2010 |
MitoK(ATP) opener, diazoxide, reduces neuronal damage after middle cerebral artery occlusion in the rat.
Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Diazoxide; Infarction, Middle | 2002 |
The neuroprotection conferred by activating the mitochondrial ATP-sensitive K+ channel is mediated by inhibiting the mitochondrial permeability transition pore.
Topics: Animals; Atractyloside; Brain Infarction; Cyclosporine; Diazoxide; Dose-Response Relationship, Drug; | 2006 |
Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Brain Ischemia; Cell Survival; Cells, Culture | 2002 |