diazoxide has been researched along with Cardiovascular Pregnancy Complications in 38 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of a prospective trial to evaluate the use of diazoxide and labetalol given intravenously in the management of severe hypertensive disease in pregnancy are presented." | 9.06 | Intravenous labetalol and intravenous diazoxide in severe hypertension complicating pregnancy. ( Michael, CA, 1986) |
| "The administration of diazoxide to patients with severe hypertension in pregnancy in 60 and 150 mg doses, which are smaller than the usual 300 mg dose, is described." | 9.05 | Low-dose diazoxide in the emergency management of severe hypertension in pregnancy. ( Moodley, J; Sankar, D, 1984) |
| "We have treated 81 patients who had hypertension with slow intravenous infusion of diazoxide (15 mg/min; 5 mg/kg of body weight)." | 7.66 | Acute treatment of hypertension with slow infusion of diazoxide. ( Huysmans, FT; Koene, RA; Thien, T, 1983) |
| "Intravenous diazoxide was given to 8 patients with severe pregnancy-associated hypertension (diastolic pressure greater than or equal to 110) in the antepartum period." | 7.66 | Effect of diazoxide on the antepartum cardiotocograph in severe pregnancy-associated hypertension. ( Barr, PA; Gallery, ED, 1981) |
| "Eight patients with severe pre-eclampsia or eclampsia were treated with diazoxide." | 7.66 | Infusion of diazoxide in severe hypertension during pregnancy. ( Eskes, TK; Koene, RA; Pieters, GF; Schijf, C; Thien, T; Wijdeveld, PG, 1980) |
| "Four patients with hypertensive disorders of pregnancy were treated with intravenous diazoxide." | 7.66 | Diazoxide for the acute control of severe hypertension complicating pregnancy: a pilot study. ( Cabal, L; Freeman, RK; Neuman, J; Rabello, Y; Weiss, B, 1979) |
| "Twelve patients with either severe preeclampsia (9) or eclampsia (3) were treated with intravenous diazoxide, 300-mg bolus, for the reduction of diastolic blood pressure (less than or equal 110 torr) after the usual and customary measures had been initiated to include parenteral MgSO4 and diazepam." | 7.65 | The management of severe preeclampsia and eclampsia with intravenous diazoxide. ( Arce, JJ; Bloom, RS; Clark, JH; Davidson, EC; Hamilton, CJ; Maidman, JE; Morris, JA, 1977) |
| "The results of a prospective trial to evaluate the use of diazoxide and labetalol given intravenously in the management of severe hypertensive disease in pregnancy are presented." | 5.06 | Intravenous labetalol and intravenous diazoxide in severe hypertension complicating pregnancy. ( Michael, CA, 1986) |
| "The administration of diazoxide to patients with severe hypertension in pregnancy in 60 and 150 mg doses, which are smaller than the usual 300 mg dose, is described." | 5.05 | Low-dose diazoxide in the emergency management of severe hypertension in pregnancy. ( Moodley, J; Sankar, D, 1984) |
| "We have treated 81 patients who had hypertension with slow intravenous infusion of diazoxide (15 mg/min; 5 mg/kg of body weight)." | 3.66 | Acute treatment of hypertension with slow infusion of diazoxide. ( Huysmans, FT; Koene, RA; Thien, T, 1983) |
| "Intravenous diazoxide was given to 8 patients with severe pregnancy-associated hypertension (diastolic pressure greater than or equal to 110) in the antepartum period." | 3.66 | Effect of diazoxide on the antepartum cardiotocograph in severe pregnancy-associated hypertension. ( Barr, PA; Gallery, ED, 1981) |
| "Eight patients with severe pre-eclampsia or eclampsia were treated with diazoxide." | 3.66 | Infusion of diazoxide in severe hypertension during pregnancy. ( Eskes, TK; Koene, RA; Pieters, GF; Schijf, C; Thien, T; Wijdeveld, PG, 1980) |
| "Four patients with hypertensive disorders of pregnancy were treated with intravenous diazoxide." | 3.66 | Diazoxide for the acute control of severe hypertension complicating pregnancy: a pilot study. ( Cabal, L; Freeman, RK; Neuman, J; Rabello, Y; Weiss, B, 1979) |
| "Twelve patients with either severe preeclampsia (9) or eclampsia (3) were treated with intravenous diazoxide, 300-mg bolus, for the reduction of diastolic blood pressure (less than or equal 110 torr) after the usual and customary measures had been initiated to include parenteral MgSO4 and diazepam." | 3.65 | The management of severe preeclampsia and eclampsia with intravenous diazoxide. ( Arce, JJ; Bloom, RS; Clark, JH; Davidson, EC; Hamilton, CJ; Maidman, JE; Morris, JA, 1977) |
| "Hypertension in pregnancy has implications for both maternal and fetal welfare." | 2.37 | Hypertension in pregnancy. Pathophysiology and management. ( Lubbe, WF, 1984) |
| "Although hypertension is the most common and significant risk factor in pregnancy, the risks can be minimized with careful supervision and therapy." | 2.37 | Hypertension in pregnant women. ( Gallery, ED, 1985) |
| "Diazoxide is a potent antihypertensive agent due to its peripheral vasodilator action." | 1.27 | Effects of diazoxide on maternal and fetal circulations in normotensive and hypertensive pregnant sheep. ( Kuijken, JP; Wallenburg, HC, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moodley, J | 2 |
| Chesley, LC | 1 |
| Hayashi, RH | 1 |
| Liedholm, H | 1 |
| Melander, A | 1 |
| Lubbe, WF | 1 |
| Redman, CW | 5 |
| Wallenburg, HC | 1 |
| Kuijken, JP | 1 |
| Huysmans, FT | 1 |
| Thien, T | 2 |
| Koene, RA | 2 |
| Sankar, D | 1 |
| Roelofse, JA | 1 |
| Smith, MJ | 1 |
| Aynsley-Green, A | 1 |
| Barr, PA | 1 |
| Gallery, ED | 2 |
| MacLean, AB | 1 |
| Doig, JR | 1 |
| Chatfield, WR | 1 |
| Aickin, DR | 1 |
| Milsap, RL | 1 |
| Auld, PA | 1 |
| Berkowitz, RL | 1 |
| Ram, CV | 1 |
| Caramelo Díaz, C | 1 |
| González Medel, J | 1 |
| Díaz Curiel, M | 1 |
| Fernández Guerrero, M | 1 |
| Casado, S | 1 |
| Schijf, C | 1 |
| Pieters, GF | 1 |
| Eskes, TK | 1 |
| Wijdeveld, PG | 1 |
| Walters, WA | 1 |
| Neuman, J | 1 |
| Weiss, B | 1 |
| Rabello, Y | 1 |
| Cabal, L | 1 |
| Freeman, RK | 1 |
| Retzke, U | 1 |
| Schwarz, R | 1 |
| Lauckner, W | 1 |
| Morris, JA | 2 |
| Arce, JJ | 1 |
| Hamilton, CJ | 1 |
| Davidson, EC | 1 |
| Maidman, JE | 1 |
| Clark, JH | 1 |
| Bloom, RS | 1 |
| Finnerty, FA | 2 |
| Woods, JR | 1 |
| Brinkman, CR | 1 |
| Naden, RP | 1 |
| Rubin, PC | 1 |
| Brengman, SL | 1 |
| Burns, MK | 1 |
| Michael, CA | 1 |
| Dudley, DK | 1 |
| Horvath, JS | 1 |
| Korda, A | 1 |
| Child, A | 1 |
| Henderson-Smart, D | 1 |
| Phippard, A | 1 |
| Duggin, GG | 1 |
| Hall, BM | 1 |
| Tiller, DJ | 1 |
| Martin, JD | 1 |
| Fernandes, M | 1 |
| Kim, KE | 1 |
| Moyer, JH | 1 |
| Pennington, JC | 1 |
| Picker, RH | 1 |
13 reviews available for diazoxide and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
The management of hypertension in pregnancy: A review.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anesthesia, Epidural; Anesthesia, Obstetrical; Anticoagu | 1980 |
The control of hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsi | 1981 |
Management of the pregnant patient with chronic hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Humans; Hydralaz | 1983 |
Hypertension in pregnancy. Pathophysiology and management.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Clon | 1984 |
The management of hypertension in pregnancy.
Topics: Cerebrovascular Circulation; Clinical Trials as Topic; Diazoxide; Diuretics; Female; Humans; Hydrala | 1984 |
Anti-hypertensive drugs in the pregnant patient.
Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide | 1980 |
Treatment of hypertension in pregnancy.
Topics: Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertension; Methyldopa; Placenta; Pre-Eclampsia | 1980 |
Hypertensive emergencies: recognition and management.
Topics: Acute Disease; Aortic Aneurysm; Aortic Dissection; Brain Diseases; Cerebral Hemorrhage; Coronary Dis | 1982 |
The use of antihypertensive drugs in hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretic | 1977 |
Hypertension in pregnant women.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Delivery, Obstetric; Diazoxide; Emergencies; F | 1985 |
Antihypertensive drugs in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Fetus; Humans; H | 1985 |
Treatment of hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsia; Female; Human | 1986 |
Hypertensive emergencies.
Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume | 1974 |
3 trials available for diazoxide and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
The management of hypertension in pregnancy.
Topics: Cerebrovascular Circulation; Clinical Trials as Topic; Diazoxide; Diuretics; Female; Humans; Hydrala | 1984 |
Low-dose diazoxide in the emergency management of severe hypertension in pregnancy.
Topics: Blood Pressure; Diazoxide; Emergencies; Female; Fetal Heart; Heart Rate; Humans; Hypertension; Pregn | 1984 |
Intravenous labetalol and intravenous diazoxide in severe hypertension complicating pregnancy.
Topics: Adolescent; Adult; Birth Weight; Clinical Trials as Topic; Delivery, Obstetric; Diazoxide; Female; H | 1986 |
23 other studies available for diazoxide and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
Drug selection in the treatment of pregnancy hypertension. A survey.
Topics: Adrenal Glands; Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Card | 1984 |
Effects of diazoxide on maternal and fetal circulations in normotensive and hypertensive pregnant sheep.
Topics: Animals; Blood Circulation; Diazoxide; Female; Fetus; Hemodynamics; Hypertension; Plasma Substitutes | 1984 |
Acute treatment of hypertension with slow infusion of diazoxide.
Topics: Adult; Blood Pressure; Diazoxide; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Inf | 1983 |
Anaesthesia and diazoxide.
Topics: Anesthesia, Obstetrical; Cesarean Section; Diazoxide; Female; Humans; Hypertension; Pregnancy; Pregn | 1984 |
Neonatal hyperglycaemia after prolonged maternal treatment with diazoxide.
Topics: Adult; Diazoxide; Female; Humans; Hyperglycemia; Hypertension; Infant, Newborn; Infant, Newborn, Dis | 1982 |
Effect of diazoxide on the antepartum cardiotocograph in severe pregnancy-associated hypertension.
Topics: Blood Pressure; Diazoxide; Female; Fetal Heart; Fetal Monitoring; Heart Rate; Humans; Hypertension; | 1981 |
Small-dose diazoxide administration in pregnancy.
Topics: Blood Pressure; Diazoxide; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complic | 1981 |
Neonatal hyperglycemia following maternal diazoxide administration.
Topics: Adult; Blood Glucose; Diazoxide; Female; Humans; Hyperglycemia; Hypertension; Infant, Newborn; Infan | 1980 |
[Infusion of diazoxide in severe arterial hypertension].
Topics: Adolescent; Adult; Aged; Blood Pressure; Diazoxide; Female; Humans; Hypertension; Infusions, Parente | 1982 |
Infusion of diazoxide in severe hypertension during pregnancy.
Topics: Adult; Diazoxide; Eclampsia; Female; Humans; Hypertension; Infusions, Intra-Arterial; Pre-Eclampsia; | 1980 |
Review: the significance and management of raised blood pressure in pregnancy.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Chlormethiazole; Clonidine; Diazepam; D | 1979 |
Diazoxide for the acute control of severe hypertension complicating pregnancy: a pilot study.
Topics: Adult; Diazoxide; Female; Fetal Heart; Heart Rate; Humans; Hyperglycemia; Hypertension; Infant, Newb | 1979 |
[The haemodynamic principle of action of diazoxide (hypertonalum) in the treatment of acute hypertensive crises in late pregnant women (author's transl)].
Topics: Acute Disease; Cardiac Output; Diazoxide; Eclampsia; Female; Heart Rate; Humans; Hypertension; Pregn | 1979 |
The management of severe preeclampsia and eclampsia with intravenous diazoxide.
Topics: Adolescent; Adult; Cesarean Section; Diazoxide; Eclampsia; Female; Humans; Hypertension; Hypoglycemi | 1977 |
Use of diazoxide for hypertensive disorders of pregnancy.
Topics: Diazoxide; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular | 1977 |
Hypertension in pregnancy.
Topics: Abortion, Therapeutic; Adult; Blood Pressure; Diazoxide; Diuretics; Female; Furosemide; Guanethidine | 1975 |
The treatment of gestational hypertension.
Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype | 1975 |
Hypertensive crisis in L & D.
Topics: Adult; Critical Care; Diazoxide; Female; Humans; Hydralazine; Hypertension; Magnesium Sulfate; Nitro | 1988 |
Minibolus diazoxide in the management of severe hypertension in pregnancy.
Topics: Apgar Score; Birth Weight; Diazoxide; Female; Humans; Hypertension; Infant, Newborn; Infant, Newborn | 1985 |
Hypertension in pregnancy. A study of 142 women presenting before 32 weeks' gestation.
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hydralazine; Hypertension; Infant Mor | 1985 |
The management of hypertensive disease of pregnancy.
Topics: Blood Pressure; Diazoxide; Eclampsia; Edema; Estrogens; Female; Guanethidine; Humans; Hypertension; | 1974 |
Diazoxide and the treatment of the acute hypertensive emergency in obstetrics.
Topics: Acute Disease; Adolescent; Adult; Diazoxide; Eclampsia; Emergencies; Female; Humans; Hypertension; I | 1972 |
Advantages and disadvantages of furosemide in the edematous states of pregnancy.
Topics: Diazoxide; Edema; Female; Furosemide; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Car | 1969 |