diazoxide has been researched along with Cancer of Pancreas in 126 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazoxide is recognized as an effective medical treatment for insulinoma." | 7.91 | Clinical outcomes of 20 Japanese patients with insulinoma treated with diazoxide. ( Hashimoto, K; Izumiyama, H; Kudo, A; Minami, I; Niitsu, Y; Ogawa, Y; Ota, K; Satou, F; Tanabe, M; Tsujino, M; Yamada, T; Yoshimoto, T, 2019) |
| " The patient received treatment with oral diazoxide and continuous glucose monitoring (CGM), which resulted in the resolution of the hypoglycemia." | 7.81 | Insulinoma in a patient with chronic renal failure due to type 2 diabetes mellitus treated effectively with diazoxide. ( Aso, Y; Hiraishi, H; Kojima, M; Shimizu, M; Suzuki, K; Tsuchida, K, 2015) |
| " We diagnosed her with insulinoma and initiated diazoxide treatment to prevent hypoglycemia." | 7.80 | Thrombocytopenia induced by diazoxide in a patient with an insulinoma. ( Adachi, J; Kakihana, K; Mimura, M; Minami, I; Watanabe, T, 2014) |
| "Surgery is the ideal treatment of insulinoma." | 5.72 | Preoperative treatment of benign insulinoma: diazoxide or somatostatin analogues? ( Bertrand, C; Donckier, JE; Gilliaux, Q; Hanon, F, 2022) |
| "Primary treatment of insulinoma is surgical resection of the tumor." | 5.32 | [Treatment of insulinoma with diazoxide]. ( Cristino, A; Fainstein, D; González Pardo, FO; Lasdica, S; Mateu, MV, 2003) |
| "Thus, alpha-TC glucagonoma cells contain ATP-sensitive K+ channels that regulate glucagon release, yet allow inhibition of hormone release by glucose." | 5.29 | Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells. ( Buettger, C; Epstein, AJ; Hang, TL; Matschinsky, FM; Ronner, P, 1993) |
| " Medical control of the hormonal syndrome with agents such as diazoxide for insulinoma, omeprazole for gastrinoma, and octreotide for vipoma and glucagonoma allows an orderly and thorough investigation for associated endocrinopathies and comorbid medical conditions." | 4.79 | Islet cell tumors. ( Stabile, BE, 1997) |
| "Diazoxide is recognized as an effective medical treatment for insulinoma." | 3.91 | Clinical outcomes of 20 Japanese patients with insulinoma treated with diazoxide. ( Hashimoto, K; Izumiyama, H; Kudo, A; Minami, I; Niitsu, Y; Ogawa, Y; Ota, K; Satou, F; Tanabe, M; Tsujino, M; Yamada, T; Yoshimoto, T, 2019) |
| " The patient received treatment with oral diazoxide and continuous glucose monitoring (CGM), which resulted in the resolution of the hypoglycemia." | 3.81 | Insulinoma in a patient with chronic renal failure due to type 2 diabetes mellitus treated effectively with diazoxide. ( Aso, Y; Hiraishi, H; Kojima, M; Shimizu, M; Suzuki, K; Tsuchida, K, 2015) |
| " We diagnosed her with insulinoma and initiated diazoxide treatment to prevent hypoglycemia." | 3.80 | Thrombocytopenia induced by diazoxide in a patient with an insulinoma. ( Adachi, J; Kakihana, K; Mimura, M; Minami, I; Watanabe, T, 2014) |
| "Diazoxide treatment for presumptive insulinoma was started at a dosage of 5 mg/kg (2." | 3.79 | Diagnosis and treatment of an insulinoma in a guinea pig (Cavia porcellus). ( Hess, LR; Ravich, ML; Reavill, DR, 2013) |
| "In conclusion, this case may suggest that biologic behavior may differ from histological behavior in insulinoma and platin-based systemic chemotherapy may provide some benefit in patients those who had diazoxide- and octreotide-resistant tumors." | 3.76 | Rapidly progressing malignant insulinoma presented with multiple liver metastases: a case report. ( Akkaya, H; Askin, E; Bascil Tutuncu, N; Erdogan, A; Fatih, K; Hampar, A; Kose, F; Ozgur, O; Ozyilkan, O; Tutuncu, NB, 2010) |
| "Organic hyperinsulinism is treated as a rule conservatively with diazoxide (Proglicem) which has a hyperglycaemic effect." | 3.69 | [The effect of Proglicem in patients with an organic hyperinsulinism syndrome]. ( Justová, V; Sindelka, G; Skrha, J; Svacina, S; Wichterle, D, 1994) |
| " We describe a 72-year-old lady who initially presented with episodic hypoglycemia secondary to an insulinoma that was controlled by diazoxide." | 3.69 | Relapse of medically treated insulinoma following the development of thyrotoxicosis: an assessment of potential mechanisms. ( Alberti, KG; Kendall-Taylor, P; Trajano, LR; Walker, M, 1994) |
| "The effect on insulin release of efaroxan, an alpha 2-adrenoceptor antagonist and a highly potent drug at imidazoline I1 receptors, and the effects of seven other imidazoline compounds selective for the imidazoline I1 or I2 receptors, were studied in the rat insulinoma cell line RIN-5AH." | 3.69 | Imidazolines stimulate release of insulin from RIN-5AH cells independently from imidazoline I1 and I2 receptors. ( Haque, M; Kulkarni, RN; MacDermot, J; Olmos, G, 1994) |
| "We studied the release of insulin, glucagon, and somatostatin in response to glucose, glyceraldehyde (GA), and alpha-ketoisocaproate (KIC) from rat kidneys containing transplanted insulinomas." | 3.67 | Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney. ( Ferguson, DC; Hoenig, M; Matschinsky, FM, 1984) |
| " The enzyme in the insulinomas, but not that in the nearby pancreases, was inhibited by diazoxide, which is a known inhibitor of insulin secretion in vitro and in vivo." | 3.66 | Increased mitochondrial glycerol phosphate dehydrogenase activity in insulinomas of two hypoglycemic infants. ( MacDonald, MJ; Pellett, JR; Warner, TF, 1983) |
| " In the patient with beta-cell adenoma but not in the one with carcinoma, plasma insulin concentrations decreased promptly and markedly, and blood glucose increased during diazoxide and somatostatin infusion." | 3.66 | Artificial beta-cell application in two cases of insulinoma: a different pattern in beta-cell adenoma and carcinoma. ( Angeletti, G; Brunetti, P; Bueti, A; Calabrese, G; De Angelis, M; Massi-Benedetti, M; Puxeddu, A; Santeusanio, F; Scionti, L, 1979) |
| "Hypoglycemia was not repeated on endocrinological examination, even while fasting." | 1.72 | Diagnosis and Treatment Course of Insulinoma Presenting as Hypoglycemia Unawareness Using a Factory-Calibrated Continuous Glucose Monitoring System. ( Aida, A; Noto, H, 2022) |
| "Surgery is the ideal treatment of insulinoma." | 1.72 | Preoperative treatment of benign insulinoma: diazoxide or somatostatin analogues? ( Bertrand, C; Donckier, JE; Gilliaux, Q; Hanon, F, 2022) |
| "Insulinomas are the most common cause of EHH." | 1.56 | Changing Insulinoma Management Due to Incidentally Discovered Metastasis: A Case Report. ( Chow, LS; Froelich, J; Madan, R; Mettler, T, 2020) |
| "Nesidioblastosis is a rare cause of adult hypoglycemia." | 1.51 | A Case Report of Insulinoma Relapse on Background Nesidioblastosis: A Rare Cause of Adult Hypoglycemia. ( Bonora, E; Castelli, C; Dauriz, M; Ferdeghini, M; Fuini, A; Landoni, L; Malleo, G; Maneschi, C; Moghetti, P; Tomezzoli, A, 2019) |
| "Most cases of insulinomas are benign." | 1.43 | A malignant cause of hypoglycaemia: a metastatic insulin-secreting pancreatic neuroendocrine carcinoma. ( Berberabe, A; Pagsisihan, D; Palugod-Lopez, EG; Sandoval, MA, 2016) |
| "Insulinomas are β-cell tumors that cause hypoglycemia through inappropriate secretion of insulin." | 1.42 | Human Insulinomas Show Distinct Patterns of Insulin Secretion In Vitro. ( Guiot, Y; Henquin, JC; Nenquin, M; Rahier, J; Sempoux, C, 2015) |
| "Although nesidioblastosis is a rare but well-recognized disorder of persistent hypoglycaemia in infants, it is extremely rare in adults." | 1.42 | Nesidioblastosis coexisting with non-functioning islet cell tumour in an adult. ( Blandamura, S; Merigliano, S; Pastorelli, D; Sperti, C; Valli, V, 2015) |
| "Malignant insulinoma is an infrequent functional endocrine tumor of the pancreas." | 1.39 | Management of malignant insulinoma. ( Caballero-Díaz, C; Camps Herrero, C; Civera-Andrés, M; Ferrer-García, JC; Iranzo González-Cruz, V; Merchante-Alfaro, A; Morillas-Ariño, C; Navas-DeSolís, S; Sánchez-Juan, C, 2013) |
| "Primary treatment of insulinoma is surgical resection of the tumor." | 1.32 | [Treatment of insulinoma with diazoxide]. ( Cristino, A; Fainstein, D; González Pardo, FO; Lasdica, S; Mateu, MV, 2003) |
| " By applying the patch-clamp technique, dose-response curves for ATP and the sulfonylurea tolbutamide were obtained in inside-out patches." | 1.30 | RIN14B: a pancreatic delta-cell line that maintains functional ATP-dependent K+ channels and capability to secrete insulin under conditions where it no longer secretes somatostatin. ( Berggren, PO; Bränström, R; Höög, A; Larsson, O; Wahl, MA, 1997) |
| "Thus, alpha-TC glucagonoma cells contain ATP-sensitive K+ channels that regulate glucagon release, yet allow inhibition of hormone release by glucose." | 1.29 | Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells. ( Buettger, C; Epstein, AJ; Hang, TL; Matschinsky, FM; Ronner, P, 1993) |
| "Chlorpromazine inhibition was observed when KATP channels were activated by ATP depletion or by direct treatment with a classical KATP channel opener, diazoxide." | 1.28 | Chlorpromazine and related phenothiazines inhibit the ATP-sensitive K+ channel. ( De Weille, JR; Lazdunski, M; Müller, M, 1991) |
| "Three cases in which seizure disorder was first noticed were examined in the last seven years; low fasting glucose and high serum insulin levels then led to the diagnosis of severe hypoglycemia secondary to nesidioblastosis." | 1.26 | Nesidioblastosis in children. ( Danis, RK; Garvin, PJ; Knight, J; Lewis, JE; Willman, VL, 1980) |
| "To avoid mental retardation, surgical intervention should not be considered as a last resort." | 1.26 | Near-total pancreatectomy in persistent infantile hypoglycemia. ( Moazam, F; Rodgers, BM; Rosenbloom, AL; Talbert, JL, 1982) |
| "Islet cell adenomas are an important consideration in infants and children with hypoglycemia due to hyperinsulinism." | 1.26 | Pancreatic adenomas in infants and children: current surgical management. ( Baker, L; Bishop, HC; Gauderer, M; Stanley, CA, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 73 (57.94) | 18.7374 |
| 1990's | 22 (17.46) | 18.2507 |
| 2000's | 10 (7.94) | 29.6817 |
| 2010's | 17 (13.49) | 24.3611 |
| 2020's | 4 (3.17) | 2.80 |
| Authors | Studies |
|---|---|
| Aida, A | 1 |
| Noto, H | 1 |
| Gilliaux, Q | 1 |
| Bertrand, C | 1 |
| Hanon, F | 1 |
| Donckier, JE | 1 |
| Madan, R | 1 |
| Mettler, T | 1 |
| Froelich, J | 1 |
| Chow, LS | 1 |
| Sileo, F | 1 |
| Cangiano, B | 1 |
| Cacciatore, C | 1 |
| Amarù, J | 1 |
| Gatto, F | 1 |
| Albertelli, M | 1 |
| Falconi, M | 1 |
| Vitale, G | 1 |
| Persani, L | 1 |
| Niitsu, Y | 1 |
| Minami, I | 2 |
| Izumiyama, H | 1 |
| Hashimoto, K | 1 |
| Yoshimoto, T | 1 |
| Satou, F | 1 |
| Tsujino, M | 1 |
| Ota, K | 1 |
| Kudo, A | 1 |
| Tanabe, M | 1 |
| Yamada, T | 1 |
| Ogawa, Y | 1 |
| Dauriz, M | 1 |
| Maneschi, C | 1 |
| Castelli, C | 1 |
| Tomezzoli, A | 1 |
| Fuini, A | 1 |
| Landoni, L | 1 |
| Malleo, G | 1 |
| Ferdeghini, M | 1 |
| Bonora, E | 1 |
| Moghetti, P | 1 |
| Ferrer-García, JC | 1 |
| Iranzo González-Cruz, V | 1 |
| Navas-DeSolís, S | 1 |
| Civera-Andrés, M | 1 |
| Morillas-Ariño, C | 1 |
| Merchante-Alfaro, A | 1 |
| Caballero-Díaz, C | 1 |
| Sánchez-Juan, C | 1 |
| Camps Herrero, C | 1 |
| Tabarin, A | 1 |
| Goichot, B | 1 |
| Luppi, P | 1 |
| Drain, P | 1 |
| Adachi, J | 1 |
| Mimura, M | 1 |
| Kakihana, K | 1 |
| Watanabe, T | 1 |
| Shimizu, M | 1 |
| Suzuki, K | 1 |
| Tsuchida, K | 1 |
| Kojima, M | 1 |
| Hiraishi, H | 1 |
| Aso, Y | 1 |
| Yoshioka, M | 1 |
| Shibata, S | 1 |
| Uchinami, H | 1 |
| Watanabe, G | 1 |
| Miyazawa, H | 1 |
| Iida, M | 1 |
| Yoshida, M | 1 |
| Yoshioka, T | 1 |
| Nanjo, H | 1 |
| Yamamoto, Y | 1 |
| Henquin, JC | 1 |
| Nenquin, M | 1 |
| Guiot, Y | 1 |
| Rahier, J | 2 |
| Sempoux, C | 1 |
| Valli, V | 1 |
| Blandamura, S | 1 |
| Pastorelli, D | 1 |
| Merigliano, S | 1 |
| Sperti, C | 1 |
| Sandoval, MA | 1 |
| Pagsisihan, D | 1 |
| Berberabe, A | 1 |
| Palugod-Lopez, EG | 1 |
| Shao, Y | 1 |
| Qu, YQ | 1 |
| Wang, XL | 1 |
| Song, ZG | 1 |
| Guo, QH | 1 |
| Dou, JT | 1 |
| Ba, JM | 1 |
| Lü, ZH | 1 |
| Mu, YM | 1 |
| Erdogan, A | 1 |
| Askin, E | 1 |
| Kose, F | 1 |
| Fatih, K | 1 |
| Akkaya, H | 1 |
| Hampar, A | 1 |
| Bascil Tutuncu, N | 1 |
| Tutuncu, NB | 1 |
| Ozyilkan, O | 1 |
| Ozgur, O | 1 |
| Ross, JJ | 1 |
| Vaidya, A | 1 |
| Kaiser, UB | 1 |
| Swaminathan, K | 1 |
| Young, R | 1 |
| Reid, W | 1 |
| Levy, MJ | 1 |
| Thompson, GB | 1 |
| Topazian, MD | 1 |
| Callstrom, MR | 1 |
| Grant, CS | 1 |
| Vella, A | 1 |
| Hess, LR | 1 |
| Ravich, ML | 1 |
| Reavill, DR | 1 |
| Martinez-Ibanez, V | 1 |
| Gussinyer, M | 1 |
| Toran, N | 1 |
| Lloret, J | 1 |
| Abad, P | 1 |
| Carrascosa, A | 1 |
| Boix-Ochoa, J | 1 |
| Hussain, K | 1 |
| Cosgrove, KE | 2 |
| Shepherd, RM | 2 |
| Chapman, JC | 2 |
| Swift, SM | 1 |
| Smith, VV | 1 |
| Kassem, SA | 1 |
| Glaser, B | 1 |
| Lindley, KJ | 1 |
| Aynsley-Green, A | 1 |
| Dunne, MJ | 4 |
| Mateu, MV | 1 |
| González Pardo, FO | 1 |
| Cristino, A | 1 |
| Lasdica, S | 1 |
| Fainstein, D | 1 |
| LUNDVALL, O | 1 |
| JOHNSSON, S | 1 |
| ERNESTI, M | 1 |
| MITCHELL, ML | 1 |
| RABEN, MS | 1 |
| GILBOA, Y | 1 |
| MARKS, V | 2 |
| ROSE, FC | 1 |
| SAMOLS, E | 1 |
| Merglen, A | 1 |
| Theander, S | 1 |
| Rubi, B | 1 |
| Chaffard, G | 1 |
| Wollheim, CB | 1 |
| Maechler, P | 1 |
| Arita, Y | 1 |
| Ito, T | 1 |
| Park, KH | 2 |
| Akaike, T | 1 |
| Arao, T | 1 |
| Okada, Y | 1 |
| Hirose, A | 1 |
| Tanaka, Y | 1 |
| Wright, J | 1 |
| Abolfathi, A | 1 |
| Penman, E | 1 |
| Turner, RC | 1 |
| Dick, R | 1 |
| Lee, EC | 1 |
| Hoenig, M | 1 |
| Ferguson, DC | 1 |
| Matschinsky, FM | 2 |
| Knight, J | 1 |
| Garvin, PJ | 1 |
| Danis, RK | 1 |
| Lewis, JE | 1 |
| Willman, VL | 1 |
| Burch, PG | 1 |
| McLeskey, CH | 1 |
| Haemers, S | 1 |
| Rottiers, R | 1 |
| Parker, AJ | 1 |
| Musselman, EM | 1 |
| O'Brien, D | 1 |
| Calzoni, D | 1 |
| Guarneri, A | 1 |
| Santamaria, A | 1 |
| Moazam, F | 1 |
| Rodgers, BM | 1 |
| Talbert, JL | 1 |
| Rosenbloom, AL | 1 |
| Wirsching, R | 1 |
| Spelsberg, F | 1 |
| Landgraf, R | 1 |
| Tamburrano, G | 3 |
| Lala, A | 1 |
| Mauceri, M | 1 |
| Leonetti, F | 1 |
| Libianchi, S | 1 |
| Andreani, D | 3 |
| MacDonald, MJ | 1 |
| Warner, TF | 1 |
| Pellett, JR | 1 |
| Paletto, AE | 1 |
| Morino, F | 1 |
| Boltri, F | 1 |
| Camandona, M | 1 |
| Robecchi, A | 1 |
| Hammond, PJ | 1 |
| Bloom, SR | 1 |
| Yagi, M | 1 |
| Shiraiwa, K | 1 |
| Abiko, M | 1 |
| Sakuma, H | 1 |
| Hirai, S | 1 |
| Olmos, G | 1 |
| Kulkarni, RN | 1 |
| Haque, M | 1 |
| MacDermot, J | 1 |
| Walker, M | 1 |
| Trajano, LR | 1 |
| Alberti, KG | 1 |
| Kendall-Taylor, P | 1 |
| Sindelka, G | 1 |
| Skrha, J | 2 |
| Svacina, S | 1 |
| Justová, V | 2 |
| Wichterle, D | 1 |
| Jaggar, JH | 1 |
| Harding, EA | 1 |
| Ayton, BA | 1 |
| Hilgertová, J | 1 |
| Ronner, P | 1 |
| Hang, TL | 1 |
| Epstein, AJ | 1 |
| Buettger, C | 1 |
| Sjöholm, A | 1 |
| Arkhammar, P | 1 |
| Welsh, N | 1 |
| Bokvist, K | 1 |
| Rorsman, P | 1 |
| Hallberg, A | 1 |
| Nilsson, T | 1 |
| Welsh, M | 1 |
| Berggren, PO | 2 |
| Martín, F | 1 |
| Soria, B | 1 |
| Weinhaus, AJ | 1 |
| Poronnik, P | 1 |
| Tuch, BE | 1 |
| Cook, DI | 1 |
| Bränström, R | 1 |
| Höög, A | 1 |
| Wahl, MA | 1 |
| Larsson, O | 1 |
| Stabile, BE | 1 |
| Fournet, JC | 1 |
| Verkarre, V | 1 |
| De Lonlay, P | 1 |
| Brunelle, F | 1 |
| Robert, JJ | 1 |
| Nihoul-Fékété, C | 1 |
| Saudubray, JM | 1 |
| Junien, C | 1 |
| McClenaghan, NH | 2 |
| Hashmi, MN | 1 |
| Giesberts, AN | 1 |
| White, SJ | 1 |
| Ammälä, C | 1 |
| Flatt, PR | 2 |
| Kim, SW | 1 |
| Bae, YH | 1 |
| Shaer, AJ | 1 |
| Fajans, SS | 2 |
| Floyd, JC | 2 |
| Berger, H | 1 |
| Donzeau, JP | 1 |
| Tricoire, J | 1 |
| Darnaud, J | 1 |
| Arlet, P | 1 |
| Couret, B | 1 |
| Bernardet, P | 1 |
| Gouzi, JL | 1 |
| Vaysse, C | 1 |
| Bonhoure, JP | 1 |
| Calazel, P | 1 |
| Kraybill, WG | 1 |
| Anderson, DD | 1 |
| Lindell, TD | 1 |
| Fletcher, WS | 1 |
| Habbick, BF | 1 |
| Cram, RW | 1 |
| Miller, KR | 1 |
| Johnson, RK | 1 |
| Rubens, R | 1 |
| Carlier, A | 1 |
| Thiery, M | 1 |
| Vermeulen, A | 1 |
| Bouderlique, C | 1 |
| Delaitre, R | 1 |
| Bigorgne, JC | 1 |
| Bertrand, G | 1 |
| Fressinaud, P | 1 |
| Guntz, M | 1 |
| Jeschke, R | 1 |
| Romen, W | 1 |
| Thanner, F | 1 |
| Niggemeyer, H | 1 |
| Gauderer, M | 1 |
| Stanley, CA | 1 |
| Baker, L | 2 |
| Bishop, HC | 2 |
| Abascal, J | 1 |
| Farndon, JR | 2 |
| Johnston, ID | 2 |
| Panizon, F | 1 |
| Ventura, A | 1 |
| Tamburrano, S | 1 |
| Natoli, C | 1 |
| Federspil, G | 1 |
| Zaccaria, M | 1 |
| De Palo, C | 1 |
| Zago, E | 1 |
| Erle, G | 1 |
| Sicolo, N | 1 |
| Scandellari, C | 1 |
| Le Quesne, LP | 2 |
| Nabarro, JD | 1 |
| Kurtz, A | 1 |
| Zweig, S | 1 |
| Brunetti, P | 1 |
| Santeusanio, F | 1 |
| Puxeddu, A | 1 |
| Massi-Benedetti, M | 1 |
| Calabrese, G | 1 |
| Angeletti, G | 1 |
| Bueti, A | 1 |
| Scionti, L | 1 |
| De Angelis, M | 1 |
| Kolesár, P | 1 |
| Szewczyk, A | 1 |
| De Weille, JR | 2 |
| Lazdunski, M | 2 |
| Müller, M | 1 |
| Ulrich, FE | 1 |
| Schneyer, U | 1 |
| Hädecke, J | 1 |
| Takeda, H | 1 |
| Watanabe, K | 1 |
| Suzuki, D | 1 |
| Miyano, R | 1 |
| Tanaka, K | 1 |
| Machimura, H | 1 |
| Yagame, M | 1 |
| Inoue, W | 1 |
| Kaneshige, H | 1 |
| Sakai, H | 1 |
| Nauck, M | 1 |
| Stöckmann, F | 1 |
| Creutzfeldt, W | 2 |
| Bjerke, HS | 1 |
| Kelly, RE | 1 |
| Geffner, ME | 1 |
| Fonkalsrud, EW | 1 |
| Bahloul, F | 1 |
| Goode, PN | 1 |
| Anderson, J | 1 |
| Morte, JA | 1 |
| Boden, G | 1 |
| Ryan, IG | 1 |
| Shuman, CR | 1 |
| Nelson, RW | 1 |
| Foodman, MS | 1 |
| Bell, WE | 1 |
| Samaan, NA | 1 |
| Longnecker, DS | 1 |
| Cohen, MS | 1 |
| Bower, RH | 1 |
| Fidler, SM | 1 |
| Johnsonbaugh, RE | 1 |
| Sode, J | 1 |
| Croisier, JC | 1 |
| Croisier, G | 1 |
| Schaison, G | 1 |
| Cassano, C | 1 |
| Menzinger, G | 1 |
| Fallucca, F | 1 |
| Hunt, PS | 1 |
| Linquette, M | 1 |
| Fossati, P | 1 |
| Decoulx, M | 1 |
| Fourlinnie, JC | 1 |
| Mariage, P | 1 |
| Mengoli, L | 1 |
| Salinas, ED | 1 |
| Mangurten, HH | 1 |
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| Simon, WH | 1 |
| Cornblath, M | 1 |
| Drash, A | 1 |
| Kenny, F | 1 |
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| Wolff, F | 1 |
| Assan, R | 2 |
| Hanania, G | 1 |
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| Zahnd, G | 1 |
| Lefebvre, P | 2 |
| Raithel, D | 1 |
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| Schwartz, JF | 1 |
| Zwiren, GT | 1 |
| Koch, G | 1 |
| McGrath, WJ | 1 |
| Balsam, MJ | 1 |
| Hummeler, K | 1 |
| Yakovac, WC | 1 |
| Kaye, R | 1 |
| Götz, M | 1 |
| Rosenmayr, F | 1 |
| Harrell, A | 1 |
| Laurian, L | 1 |
| Ayalon, D | 1 |
| Kisch, E | 1 |
| Cordova, T | 1 |
| Sherman, BM | 1 |
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| Levin, SR | 1 |
| Karam, JH | 1 |
| Blum, MR | 1 |
| Forsham, PH | 1 |
| Saric, R | 1 |
| Moreau, F | 1 |
| Seguin, G | 1 |
| Cohen, E | 1 |
| Merlet, M | 1 |
| Lorin, JC | 1 |
| Tolloczko, T | 1 |
| Wasiutyński, A | 1 |
| Giddings, AE | 1 |
| Appleyard, WJ | 1 |
| Lloyd, J | 1 |
| Kopf, A | 1 |
| Wüstenberg, PW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes[NCT05594563] | Phase 2 | 70 participants (Anticipated) | Interventional | 2023-03-14 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for diazoxide and Cancer of Pancreas
| Article | Year |
|---|---|
[Diagnosis and treatment of insulinoma].
Topics: Antineoplastic Agents; Blood Glucose; Chemoembolization, Therapeutic; Diazoxide; Fasting; Glucagon; | 2004 |
[Localization of beta-Langerhans tumors secreting hypoglycemics].
Topics: Adenoma, Islet Cell; Angiography; Diazoxide; Humans; Insulin; Insulinoma; Intraoperative Period; Lap | 1983 |
[Islet cell cancer with organic hyperinsulinism. Clinical aspects, diagnosis and therapy].
Topics: Adenoma; Adenoma, Islet Cell; C-Peptide; Diagnosis, Differential; Diazoxide; Female; Glucagon; Human | 1982 |
Islet cell tumors.
Topics: Adenoma, Islet Cell; Diazoxide; Gastrinoma; Humans; Hypoglycemia; Insulinoma; Octreotide; Pancreatic | 1997 |
Diagnosis and medical management of insulinomas.
Topics: Adenoma, Islet Cell; Angiography; Antineoplastic Agents; Benzothiadiazines; Blood Glucose; C-Peptide | 1979 |
[Juvenile endocrine hypoglycemia].
Topics: Adenoma; Child, Preschool; Diazoxide; Folic Acid; Fructose-1,6-Diphosphatase Deficiency; Gluconeogen | 1979 |
Medical management of canine hyperinsulinism.
Topics: Adrenal Cortex Hormones; Animals; Blood Glucose; Combined Modality Therapy; Diazoxide; Diet Therapy; | 1985 |
[The hypoglycemia syndrome].
Topics: Alloxan; Angiography; Antibiotics, Antineoplastic; Blood Glucose; Diagnosis, Differential; Diazoxide | 1970 |
1 trial available for diazoxide and Cancer of Pancreas
| Article | Year |
|---|---|
[Is the medical treatment of insulinomas justified? Experience with 9 cases].
Topics: Adenoma, Islet Cell; Administration, Oral; Adult; Catheterization; Clinical Trials as Topic; Diazoxi | 1978 |
117 other studies available for diazoxide and Cancer of Pancreas
| Article | Year |
|---|---|
Diagnosis and Treatment Course of Insulinoma Presenting as Hypoglycemia Unawareness Using a Factory-Calibrated Continuous Glucose Monitoring System.
Topics: Adult; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Complications; Diazoxide; Humans; Hype | 2022 |
Preoperative treatment of benign insulinoma: diazoxide or somatostatin analogues?
Topics: Adult; Diazoxide; Humans; Insulinoma; Octreotide; Pancreatic Neoplasms; Somatostatin | 2022 |
Changing Insulinoma Management Due to Incidentally Discovered Metastasis: A Case Report.
Topics: Ablation Techniques; Bone Neoplasms; Diagnosis, Differential; Diazoxide; Endosonography; Female; Hum | 2020 |
Off-label pasireotide treatment in one insulinoma patient with an atypical presentation and intolerant to diazoxide.
Topics: Diazoxide; Humans; Insulinoma; Off-Label Use; Pancreatic Neoplasms; Somatostatin | 2020 |
Clinical outcomes of 20 Japanese patients with insulinoma treated with diazoxide.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Diazoxide; Female; Humans; Insuli | 2019 |
A Case Report of Insulinoma Relapse on Background Nesidioblastosis: A Rare Cause of Adult Hypoglycemia.
Topics: Diazoxide; Female; Humans; Hypoglycemia; Insulinoma; Middle Aged; Neoplasm Recurrence, Local; Nesidi | 2019 |
Management of malignant insulinoma.
Topics: Adult; Aged; Chemoembolization, Therapeutic; Diazoxide; Everolimus; Female; Glucocorticoids; Humans; | 2013 |
Treatment: symptomatic treatment of hypoglycaemia.
Topics: Antineoplastic Agents; Blood Glucose; Diazoxide; Everolimus; Humans; Hypoglycemia; Insulinoma; Octre | 2013 |
Autocrine C-peptide mechanism underlying INS1 beta cell adaptation to oxidative stress.
Topics: Adaptation, Physiological; Animals; Apoptosis; Autocrine Communication; C-Peptide; Cell Line, Tumor; | 2014 |
Thrombocytopenia induced by diazoxide in a patient with an insulinoma.
Topics: Biopsy; Diagnosis, Differential; Diazoxide; Female; Humans; Insulinoma; Pancreatic Neoplasms; Thromb | 2014 |
Insulinoma in a patient with chronic renal failure due to type 2 diabetes mellitus treated effectively with diazoxide.
Topics: Antihypertensive Agents; Biomarkers, Tumor; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Dia | 2015 |
The transformation of a nonfunctioning islet cell tumor of the pancreas into a proinsulinoma under conditions of lung metastasis.
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Is | 2015 |
Human Insulinomas Show Distinct Patterns of Insulin Secretion In Vitro.
Topics: Adult; Aged, 80 and over; Calcium Chloride; Diazoxide; Female; Gene Expression Regulation; Glucose; | 2015 |
Nesidioblastosis coexisting with non-functioning islet cell tumour in an adult.
Topics: Diazoxide; Female; Humans; Middle Aged; Nesidioblastosis; Pancreas; Pancreatic Neoplasms; Proinsulin | 2015 |
A malignant cause of hypoglycaemia: a metastatic insulin-secreting pancreatic neuroendocrine carcinoma.
Topics: Biopsy; Blood Glucose; C-Peptide; Carcinoma, Neuroendocrine; Diazoxide; Humans; Hyperinsulinism; Hyp | 2016 |
A malignant cause of hypoglycaemia: a metastatic insulin-secreting pancreatic neuroendocrine carcinoma.
Topics: Biopsy; Blood Glucose; C-Peptide; Carcinoma, Neuroendocrine; Diazoxide; Humans; Hyperinsulinism; Hyp | 2016 |
A malignant cause of hypoglycaemia: a metastatic insulin-secreting pancreatic neuroendocrine carcinoma.
Topics: Biopsy; Blood Glucose; C-Peptide; Carcinoma, Neuroendocrine; Diazoxide; Humans; Hyperinsulinism; Hyp | 2016 |
A malignant cause of hypoglycaemia: a metastatic insulin-secreting pancreatic neuroendocrine carcinoma.
Topics: Biopsy; Blood Glucose; C-Peptide; Carcinoma, Neuroendocrine; Diazoxide; Humans; Hyperinsulinism; Hyp | 2016 |
Malignant insulinoma: Report of 6 patients and literature review.
Topics: Adult; Diazoxide; Diuretics; Female; Humans; Hypoglycemia; Insulinoma; Liver Neoplasms; Male; Middle | 2016 |
Rapidly progressing malignant insulinoma presented with multiple liver metastases: a case report.
Topics: Antineoplastic Agents; Diazoxide; Fatal Outcome; Female; Humans; Insulinoma; Liver Neoplasms; Middle | 2010 |
Interactive medical case. Lying low.
Topics: Aged, 80 and over; Confusion; Diazoxide; Dizziness; Female; Humans; Hypoglycemia; Insulinoma; Magnet | 2011 |
The diagnosis was in her birthday party!
Topics: Aged, 80 and over; Blood Glucose; C-Peptide; Confusion; Diazoxide; Epilepsy, Tonic-Clonic; Female; H | 2012 |
US-guided ethanol ablation of insulinomas: a new treatment option.
Topics: Ablation Techniques; Adult; Aged; Aged, 80 and over; Blood Glucose; Diazoxide; Endosonography; Ethan | 2012 |
Diagnosis and treatment of an insulinoma in a guinea pig (Cavia porcellus).
Topics: Animals; Antihypertensive Agents; Blood Glucose; Diazoxide; Guinea Pigs; Insulinoma; Male; Pancreati | 2013 |
Pancreatectomy extension in persistent hyperinsulinaemic hypoglycaemia: a new strategy.
Topics: Adenoma, Islet Cell; Algorithms; Child; Child, Preschool; Diazoxide; Humans; Hyperinsulinism; Hypogl | 2002 |
Uncontrolled insulin secretion from a childhood pancreatic beta-cell adenoma is not due to the functional loss of ATP-sensitive potassium channels.
Topics: Adenoma, Islet Cell; Adenosine Triphosphate; Antihypertensive Agents; Child; Chromosomes, Human, Pai | 2002 |
[Treatment of insulinoma with diazoxide].
Topics: Aged; Diazoxide; Humans; Insulinoma; Male; Pancreatic Neoplasms; Vasodilator Agents | 2003 |
[INSULOMA TREATED WITH DIAZOXIDE].
Topics: Adenoma, Islet Cell; Antihypertensive Agents; Chlorthalidone; Diabetes Mellitus; Diazoxide; Geriatri | 1965 |
CONTROL OF HYPOGLYCAEMIA WITH DIAZOXIDE AND HUMAN GROWTH HORMONE.
Topics: Adenoma, Islet Cell; Antihypertensive Agents; Bendroflumethiazide; Blood Chemical Analysis; Blood Gl | 1965 |
HYPERINSULINISM DUE TO METASTASIZING INSULINOMA: TREATMENT WITH DIAZOXIDE.
Topics: Adenoma, Islet Cell; Diazoxide; Drug Therapy; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulino | 1965 |
Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Differentiation; Cell Division; Cytosol; Diazoxide; E | 2004 |
Probing of specific binding of synthetic sulfonylurea with the insulinoma cell line MIN6.
Topics: Calcium; Diazoxide; Glyburide; Hypoglycemic Agents; Insulinoma; Microscopy, Confocal; Pancreatic Neo | 2005 |
A rare case of adult-onset nesidioblastosis treated successfully with diazoxide.
Topics: Angiography; Blood Glucose; Diagnosis, Differential; Diazoxide; Humans; Hyperinsulinism; Hypoglycemi | 2006 |
Pancreatic somatostatinoma presenting with hypoglycaemia.
Topics: Adenocarcinoma; Adult; Chlorothiazide; Diazoxide; Female; Fluorouracil; Humans; Hypoglycemia; Pancre | 1980 |
Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney.
Topics: Adenoma, Islet Cell; Animals; Cytochalasin B; Diazoxide; Glucagon; Glucose; Glyceraldehyde; Humans; | 1984 |
Nesidioblastosis in children.
Topics: Adenoma, Islet Cell; Child, Preschool; Diazoxide; Female; Glucagon; Glucose; Humans; Hyperinsulinism | 1980 |
Insulinomas.
Topics: Adenoma, Islet Cell; Diazoxide; Humans; Insulin; Insulin Secretion; Pancreatic Neoplasms | 1981 |
Anesthesia for patients with insulinoma treatment with oral diazoxide.
Topics: Adenoma, Islet Cell; Administration, Oral; Aged; Anesthesia; Diazoxide; Enflurane; Female; Humans; I | 1981 |
Medical treatment of insulinoma.
Topics: Adenoma, Islet Cell; Antineoplastic Agents; Diazoxide; Humans; Insulinoma; Pancreatic Neoplasms | 1981 |
Diazoxide treatment of canine insulinoma.
Topics: Adenoma, Islet Cell; Administration, Oral; Animals; Blood Glucose; Diazoxide; Dog Diseases; Dogs; In | 1981 |
[Occult insulinoma. New prospects for the therapeutic approach].
Topics: Adenoma, Islet Cell; Diazoxide; Humans; Insulinoma; Pancreatic Neoplasms | 1981 |
Near-total pancreatectomy in persistent infantile hypoglycemia.
Topics: Adenoma; Adenoma, Islet Cell; Diazoxide; Female; Humans; Hyperplasia; Hypoglycemia; Infant; Infant, | 1982 |
Diazoxide infusion test in patients with single benign insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Diazoxide; Glucagon; Humans; Insulin; Insulinoma; K | 1983 |
Increased mitochondrial glycerol phosphate dehydrogenase activity in insulinomas of two hypoglycemic infants.
Topics: Adenoma, Islet Cell; Diazoxide; Female; Glycerolphosphate Dehydrogenase; Humans; Hypoglycemia; Infan | 1983 |
[Insulinoma: contribution of 21 cases].
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Diazoxide; Female; Humans; Insulinoma; Male; Middle Ag | 1984 |
Gut neuroendocrine tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dacarbazine; Diazoxide; Etoposide; Fluoro | 1994 |
Familial nesidioblastosis in two sisters.
Topics: Adenoma, Islet Cell; Diazoxide; Fatal Outcome; Female; Humans; Hypoglycemia; Infant, Newborn; Pancre | 1995 |
Imidazolines stimulate release of insulin from RIN-5AH cells independently from imidazoline I1 and I2 receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Affinity Labels; | 1994 |
Relapse of medically treated insulinoma following the development of thyrotoxicosis: an assessment of potential mechanisms.
Topics: Aged; C-Peptide; Diazoxide; Female; Humans; Hypoglycemia; Insulin; Insulin Resistance; Insulinoma; P | 1994 |
[The effect of Proglicem in patients with an organic hyperinsulinism syndrome].
Topics: Adult; Aged; Diazoxide; Female; Humans; Hyperinsulinism; Insulinoma; Male; Middle Aged; Pancreatic N | 1994 |
Activation of potassium channels by diazoxide and cromakalim in insulin-secreting cells is dependent upon internal ADP and channel run-down.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cell Line; Cromakalim; Diazoxid | 1993 |
Insulin action in patients with insulinoma influenced by pharmacological and surgical therapy.
Topics: Adult; Aged; Blood Glucose; Diazoxide; Female; Humans; Hyperinsulinism; Insulin; Insulin Resistance; | 1993 |
Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Diazoxide; Glucagon; Glucagono | 1993 |
Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Carbachol; Cytoplasm; Diazoxide; DNA, Ne | 1993 |
Glucose-induced [Ca2+]i oscillations in single human pancreatic islets.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biological Transport; Calcium; Cells, Cultured; Diaz | 1996 |
Mechanisms of arginine-induced increase in cytosolic calcium concentration in the beta-cell line NIT-1.
Topics: Animals; Arginine; Calcium; Cell Line; Cytosol; Diazoxide; Homoarginine; Insulin; Insulin Secretion; | 1997 |
RIN14B: a pancreatic delta-cell line that maintains functional ATP-dependent K+ channels and capability to secrete insulin under conditions where it no longer secretes somatostatin.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diazoxide; Electrophysiology; Insulin; Insul | 1997 |
Loss of imprinted genes and paternal SUR1 mutations lead to hyperinsulinism in focal adenomatous hyperplasia.
Topics: Adenoma, Islet Cell; ATP-Binding Cassette Transporters; Chromosomes, Human, Pair 11; Diazoxide; Drug | 1998 |
ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Benzofurans; C | 1999 |
Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion.
Topics: Animals; Arginine; Butyrates; Calcium; Calcium Channel Blockers; Calcium Channels; Coumaric Acids; D | 2000 |
Interaction of sulfonylurea-conjugated polymer with insulinoma cell line of MIN6 and its effect on insulin secretion.
Topics: Acrylic Resins; Animals; Biocompatible Materials; Culture Media, Conditioned; Diazoxide; Glucose; Gl | 2001 |
Management of hyperinsulinemia with diazoxide in an elderly hemodialysis patient.
Topics: Aged; Aged, 80 and over; Diazoxide; Humans; Hyperinsulinism; Hypoglycemia; Insulinoma; Nutrition Dis | 2001 |
Hypoglycemia: a perspective.
Topics: Adenoma, Islet Cell; Citric Acid Cycle; Diabetes Complications; Diazoxide; Female; Glucose; Glucose | 1975 |
[Letter: Obstructive cardiomyopathy revealed by diazoxide].
Topics: Adenoma, Islet Cell; Blood Pressure; Cardiomyopathy, Hypertrophic; Diazoxide; Female; Humans; Middle | 1975 |
Islet cell carcinoma of the pancreas: effective therapy with 5-fluorouracil, streptozotocin, and tubercidin.
Topics: Adenoma, Islet Cell; Adult; Diazoxide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Comb | 1976 |
Neonatal hypoglycemia resulting from islet cell adenomatosis. Successful treatment with total pancreatectomy.
Topics: Adenoma, Islet Cell; Cortisone; Diazoxide; Female; Glucose; Humans; Hypoglycemia; Infant, Newborn; I | 1977 |
Insulinoma in the dog.
Topics: Adenoma, Islet Cell; Animals; Diazoxide; Dog Diseases; Dogs; Glucagon; Hypoglycemia; Insulin; Pancre | 1977 |
Pregnancy complicated by insulinoma. Case report.
Topics: Adenoma, Islet Cell; Adult; Child, Preschool; Diazoxide; Female; Fetus; Humans; Infant; Infant, Newb | 1977 |
[Secreting langerhansian adenoma in children: clinical and biological study. Effects of diazoxide. Arteriographic localization].
Topics: Adenoma, Islet Cell; Adolescent; Diazoxide; Female; Humans; Pancreatic Neoplasms; Radiography | 1977 |
[The disease pattern of the diffuse, nesidioblastic hyperplasia of the pancreatic islets in newborn and infants (author's transl)].
Topics: Adenoma, Islet Cell; Diazoxide; Fatty Acids, Nonesterified; Humans; Hydroxybutyrates; Hypoglycemia; | 1978 |
Pancreatic adenomas in infants and children: current surgical management.
Topics: Adenoma, Islet Cell; Child; Child, Preschool; Diazoxide; Follow-Up Studies; Humans; Hyperinsulinism; | 1978 |
[The insulinomas].
Topics: Adenoma, Islet Cell; Diazoxide; Glucagon; Humans; Hyperplasia; Insulin; Insulin Secretion; Pancreati | 1979 |
[Medical treatment of spontaneous hypoglycemic syndromes].
Topics: Adenoma, Islet Cell; Chlorpromazine; Diazoxide; Fasting; Glucagon; Glucose; Humans; Hypoglycemia; Li | 1979 |
The management of insulin tumours of the pancreas.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Angiography; Blood Glucose; Diazoxide; Female; Humans; | 1979 |
Artificial beta-cell application in two cases of insulinoma: a different pattern in beta-cell adenoma and carcinoma.
Topics: Adenoma; Adenoma, Islet Cell; Artificial Organs; Blood Glucose; Carcinoma; Diagnosis, Differential; | 1979 |
[Treatment of organic hyperinsulinism with diazoxide].
Topics: Diazoxide; Female; Humans; Hyperinsulinism; Middle Aged; Pancreatic Neoplasms; Postoperative Complic | 1979 |
TMB-8 (8-(N,N-diethylamino) octyl-3,4,5-trimethoxybenzoate) inhibits the ATP-sensitive K+ channel.
Topics: Adenosine Triphosphate; Calcium Channel Blockers; Diazoxide; Electrophysiology; Gallic Acid; Insulin | 1992 |
Chlorpromazine and related phenothiazines inhibit the ATP-sensitive K+ channel.
Topics: Adenosine Triphosphate; Antipsychotic Agents; Chlorpromazine; Diazoxide; Electrophysiology; Insulino | 1991 |
[Organic hyperinsulinism. Clinical aspects--diagnosis--therapy].
Topics: Adolescent; Adult; Aged; Child; Combined Modality Therapy; Diagnosis, Differential; Diazoxide; Femal | 1991 |
A case of insulin-secreting tumor successfully treated with diazoxide.
Topics: Aged; Blood Glucose; Diazoxide; Humans; Hypoglycemia; Insulin; Insulinoma; Liver; Male; Pancreatic N | 1991 |
Evaluation of a euglycaemic clamp procedure as a diagnostic test in insulinoma patients.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Blood Glucose; Child; Diazoxide; Evaluation Studies as | 1990 |
Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells.
Topics: Adenoma, Islet Cell; Adenosine Triphosphate; Diazoxide; Glucose; Guanidines; Humans; Insulin; Insuli | 1990 |
Surgical management of islet cell dysmaturation syndrome in young children.
Topics: Adenoma; Combined Modality Therapy; Diazoxide; Humans; Hyperinsulinism; Hyperplasia; Hypoglycemia; I | 1990 |
[Hypoglycemic insular tumor or insulinoma].
Topics: Adenoma, Islet Cell; Diazoxide; Humans; Hypoglycemia; Insulinoma; Nervous System Diseases; Pancreate | 1986 |
Diazoxide in the management of patients with insulinoma.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Child, Preschool; Diazoxide; Edema; Female; Hir | 1986 |
Ineffectiveness of SMS 201-995 in severe hyperinsulinemia.
Topics: Aged; Blood Glucose; Diazoxide; Female; Humans; Hyperinsulinism; Insulin; Insulinoma; Middle Aged; O | 1988 |
Hypoglycemia due to organic hyperinsulinism in infancy.
Topics: Adenoma, Islet Cell; Adrenal Cortex Hormones; Diazoxide; Female; Humans; Hyperinsulinism; Hyperplasi | 1970 |
Inhibition of insulin release by diphenylhydantoin and diazoxide in a patient with benign insulinoma.
Topics: Adenoma, Islet Cell; Aged; Depression, Chemical; Diazoxide; Glucose; Humans; Insulin; Insulin Secret | 1973 |
[Associated pancreatic insular infiltrations. Insulinoma, gastrinoma, glucagonoma. Clinical, biological, and anatomo-pathological data].
Topics: Adenoma; Adult; Aged; Blood Glucose; Diazoxide; Duodenal Ulcer; Female; Gastrectomy; Gastrins; Gluca | 1973 |
[Pancreatic adenoma and polyendocrine pathology].
Topics: Adenoma; Adrenal Gland Neoplasms; Autopsy; Blood Glucose; Cholecystokinin; Diazoxide; Glucagon; Gluc | 1973 |
Adult hypoglycaemia associated with neoplasia. A report of three cases with a note on the use of diazoxide.
Topics: Adenoma, Islet Cell; Adult; Antihypertensive Agents; Diazoxide; Female; Fibrosarcoma; Humans; Hypogl | 1966 |
[Organic hypoglycemia due to Langerhans carcinoma. Treatment by diazoxide followed by streptozotocin].
Topics: Aged; Carcinoma; Diazoxide; Drug Therapy, Combination; Humans; Hypoglycemia; Islets of Langerhans; L | 1974 |
Blind pancreatic resection for suspected insulinoma: a review of the problem.
Topics: Adenoma; Adenoma, Islet Cell; Adult; Aged; Diabetes Mellitus; Diazoxide; Female; Humans; Hypoglycemi | 1967 |
Functioning islet cell adenoma in the newborn. Report of a case with failure of diazoxide.
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Blood Glucose; Catecholamines; Corticosterone; Dia | 1968 |
The therapeutic application of diazoxide in pediatric hypoglycemic states.
Topics: Adenoma, Islet Cell; Blood Glucose; Child; Child, Preschool; Diazoxide; Female; Glucose Tolerance Te | 1968 |
[Insulin-secreting langerhansian beta-cell tumor in a woman with diabetes mellitus. Case report and literature review].
Topics: Adenoma, Islet Cell; Diabetes Complications; Diabetic Angiopathies; Diazoxide; Humans; Hyperinsulini | 1969 |
[Diagnosis and treatment of pancreatic insulin-secreting tumors. Apropos of 2 cases observed personally].
Topics: Adenoma, Islet Cell; Administration, Oral; Aged; Diazoxide; Female; Humans; Insulin; Insulin Secreti | 1969 |
[Surgical and conservative treatment of hyperinsulinism].
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Adult; Diagnosis, Differential; Diazoxide; Female; | 1971 |
Islet cell adenomatosis and adenoma in an infant.
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Diazoxide; Glucose; Humans; Hypoglycemia; Infant, | 1971 |
[Islet cell adenoma].
Topics: Adenoma, Islet Cell; Adult; Aged; Angiography; Blood Glucose; Diazoxide; Female; Humans; Hyperinsuli | 1971 |
Surgical grand rounds from the University of Mississippi Medical Center. Management of hyperinsulinism.
Topics: Adenoma, Islet Cell; Diagnosis, Differential; Diazoxide; Dietary Carbohydrates; Female; Glucose Tole | 1971 |
Insulinomas: medical management as a successful alternative to surgical therapy.
Topics: Adenoma, Islet Cell; Child; Diazoxide; Humans; Hypoglycemia; Male; Pancreatic Neoplasms; Radiography | 1972 |
Beta cell adenoma in a child with hypoglycemia controlled with diazoxide.
Topics: Adenoma, Islet Cell; Blood Glucose; Child, Preschool; Diazoxide; Female; Glucose Tolerance Test; Hum | 1972 |
[Diazoxide treatment of infantile hypoglycaemia].
Topics: Adenoma, Islet Cell; Diagnosis, Differential; Diazoxide; Hirsutism; Humans; Hypoglycemia; Infant; Ma | 1972 |
Hypoglycemia due to hyperinsulinism treated by streptozotocin and diazoxide.
Topics: Adenoma, Islet Cell; Adult; Anti-Bacterial Agents; Diazoxide; Drug Synergism; Female; Humans; Hyperi | 1972 |
Plasma proinsulin in patients with functioning pancreatic islet cell tumors.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Antigens; Autoanalysis; Chromatography, Gel; Diazoxide | 1972 |
Pancreatic islet beta cell tumors and hyperplasia: experience in 14 Seattle hospitals.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Diazoxide; Female; Humans; Hyperinsulinism; Hyp | 1972 |
[Hyperinsulinism due to metastasizing insuloma treated with diazoxide and streptozotocin].
Topics: Adenoma, Islet Cell; Blood Glucose; Diazoxide; Female; Humans; Hyperinsulinism; Insulin; Liver Neopl | 1972 |
Proinsulin and insulin release with a human insulinoma and adjacent nonadenomatous pancreas.
Topics: Adenoma, Islet Cell; Chromatography, Gel; Diazoxide; Epinephrine; Glucose; Humans; In Vitro Techniqu | 1973 |
Biochemical and morphological investigations of 30 human insulinomas. Correlation between the tumour content of insulin and proinsulin-like components and the histological and ultrastructural appearance.
Topics: Adenoma, Islet Cell; Adult; Aged; Chromatography, Gel; Cytoplasmic Granules; Diazoxide; Female; Hist | 1973 |
[Indications and medical therapy of hypoglycemic beta-insular].
Topics: Adenoma, Islet Cell; Adrenal Cortex Hormones; Antineoplastic Agents; Carcinoma; Diazoxide; Diuretics | 1973 |
The surgical treatment of occult insulinomas: a review of the problem.
Topics: Adenoma; Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Diazoxide; Female; Follow-Up Studies; Huma | 1974 |
Effects of diphenylhydantoin upon glucose-induced insulin secretion in three patients with insulinoma.
Topics: Adenoma, Islet Cell; Administration, Oral; Adult; Blood Glucose; Diazoxide; Drug Evaluation; Drug Th | 1974 |
[Exploration of hypoglycemia].
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Diazoxide; Diet; Fasting; Glucagon; Hormones, Ectopic; | 1974 |
Beta-islet cell tumors of the pancreas: results of a study on 1,067 cases.
Topics: Adenoma, Islet Cell; Adult; Age Factors; Angiography; Child, Preschool; Diazoxide; Female; Glucose T | 1974 |
[Prolonged treatment of severe hypoglycemia with diazoxide].
Topics: Adenoma, Islet Cell; Aged; Diazoxide; Drug Eruptions; Edema; Female; Gastrointestinal Diseases; Gout | 1974 |
Diazoxide, encorton and streptozotocin in the treatment of malignant betacytoma.
Topics: Adenoma, Islet Cell; Adult; Autopsy; Diazoxide; Female; Glucose; Humans; Hypoglycemia; Liver Neoplas | 1974 |
Diagnosis and management of insulinoma.
Topics: Adenoma; Adenoma, Islet Cell; Diagnosis, Differential; Diazoxide; Humans; Insulin; Pancreatic Neopla | 1974 |
Pluriglandular syndrome with hyperinsulinism. Cardiomegaly as a possible complication of diazoxide therapy.
Topics: Blood Glucose; Blood Pressure; Cardiomegaly; Child; Diazoxide; Female; Hirsutism; Humans; Hypercalce | 1968 |
[Endocrine polyadenomatosis. General review and case report].
Topics: Adenoma; Adenoma, Islet Cell; Diazoxide; Female; Humans; Hydronephrosis; Hyperinsulinism; Hypoglycem | 1969 |