diazoxide has been researched along with Brain Injuries in 6 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Obesity is associated with increased infarct volumes and adverse outcomes following ischemic stroke." | 5.40 | Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels. ( Chen, Y; Fang, X; Jiang, Y; Xu, J; Yang, Z; Zhang, Y, 2014) |
| "Spasms were well controlled with high-dose prednisolone therapy." | 1.72 | Case Report: Neurodevelopmental Outcome in a Small-for-Gestational-Age Infant With Symptomatic Hyperinsulinemic Hypoglycemia, Gaze Preference, and Infantile Spasms. ( Chandran, S; Janardhan, K; Teoh, KW; Yap, F, 2022) |
| "Obesity is associated with increased infarct volumes and adverse outcomes following ischemic stroke." | 1.40 | Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels. ( Chen, Y; Fang, X; Jiang, Y; Xu, J; Yang, Z; Zhang, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chandran, S | 1 |
| Teoh, KW | 1 |
| Janardhan, K | 1 |
| Yap, F | 1 |
| Budinich, CS | 1 |
| Tucker, LB | 1 |
| Lowe, D | 1 |
| Rosenberger, JG | 1 |
| McCabe, JT | 1 |
| Yang, Z | 1 |
| Chen, Y | 1 |
| Zhang, Y | 1 |
| Jiang, Y | 1 |
| Fang, X | 1 |
| Xu, J | 1 |
| Wu, H | 1 |
| Wang, P | 1 |
| Li, Y | 1 |
| Wu, M | 1 |
| Lin, J | 1 |
| Huang, Z | 1 |
| Chen, M | 1 |
| Dong, Y | 1 |
| Simard, JM | 1 |
| He, X | 1 |
| Mo, X | 1 |
| Gu, H | 1 |
| Chen, F | 1 |
| Gu, Q | 1 |
| Peng, W | 1 |
| Qi, J | 1 |
| Shen, L | 1 |
| Sun, J | 1 |
| Zhang, R | 1 |
| Kj, Y | 1 |
6 other studies available for diazoxide and Brain Injuries
| Article | Year |
|---|---|
Case Report: Neurodevelopmental Outcome in a Small-for-Gestational-Age Infant With Symptomatic Hyperinsulinemic Hypoglycemia, Gaze Preference, and Infantile Spasms.
Topics: Blood Glucose; Brain Injuries; Child; Congenital Hyperinsulinism; Diazoxide; Glucose; Humans; Hypogl | 2022 |
Short and long-term motor and behavioral effects of diazoxide and dimethyl sulfoxide administration in the mouse after traumatic brain injury.
Topics: Animals; Behavior, Animal; Brain Injuries; Diazoxide; Dimethyl Sulfoxide; Male; Maze Learning; Mice; | 2013 |
Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels.
Topics: Animals; Body Weight; Brain; Brain Injuries; Brain Ischemia; Decanoic Acids; Diazoxide; Diet, High-F | 2014 |
Diazoxide Attenuates Postresuscitation Brain Injury in a Rat Model of Asphyxial Cardiac Arrest by Opening Mitochondrial ATP-Sensitive Potassium Channels.
Topics: Animals; Asphyxia; Brain Injuries; Cerebral Cortex; Diazoxide; Disease Models, Animal; Heart Arrest; | 2016 |
Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain.
Topics: Adenosine Triphosphate; Animals; Antibodies; Astrocytes; ATP-Binding Cassette Transporters; Binding, | 2003 |
Neuroprotective effect of diazoxide on brain injury induced by cerebral ischemia/reperfusion during deep hypothermia.
Topics: Analysis of Variance; Animals; Brain Injuries; Caspase 3; Cerebrovascular Circulation; Cytochromes c | 2008 |