diazoxide has been researched along with Brain Edema in 7 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Excerpt | Relevance | Reference |
---|---|---|
" We investigated the effects of mitoK(ATP) channel opener diazoxide on BBB functions during ischemia/reperfusion injury (I/R)." | 7.73 | Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability. ( Bari, F; Busija, DW; Kis, B; Lenzsér, G, 2005) |
" We investigated the effects of mitoK(ATP) channel opener diazoxide on BBB functions during ischemia/reperfusion injury (I/R)." | 3.73 | Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability. ( Bari, F; Busija, DW; Kis, B; Lenzsér, G, 2005) |
"Pretreatment with diazoxide significantly reduced the infarct volume from 6." | 1.33 | MitoKATP-channel opener protects against neuronal death in rat venous ischemia. ( Alessandri, B; Heimann, A; Kempski, O; Nakagawa, I, 2005) |
"Intracranial hypertension is a complication of hypertensive encephalopathy and may contribute to cerebral injury." | 1.26 | Intracranial pressure monitoring in severe hypertensive encephalopathy. ( Griswold, WR; James, HE; Mendoza, SA; Viney, J, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (71.43) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (28.57) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Lenzsér, G | 1 |
Kis, B | 1 |
Bari, F | 1 |
Busija, DW | 1 |
Nakagawa, I | 1 |
Alessandri, B | 1 |
Heimann, A | 1 |
Kempski, O | 1 |
Griswold, WR | 1 |
Viney, J | 1 |
Mendoza, SA | 1 |
James, HE | 1 |
Philipp, T | 1 |
Nast, HP | 1 |
Koch-Weser, J | 1 |
Breslin, DJ | 1 |
Finnerty, FA | 1 |
2 reviews available for diazoxide and Brain Edema
Article | Year |
---|---|
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Coronary D | 1974 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Diazoxide; Emergencies; Humans; Hyd | 1969 |
5 other studies available for diazoxide and Brain Edema
Article | Year |
---|---|
Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Capillary Permeability; Diazoxide; | 2005 |
MitoKATP-channel opener protects against neuronal death in rat venous ischemia.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Brain Edema; Brain Infarction; Cell Death; Ce | 2005 |
Intracranial pressure monitoring in severe hypertensive encephalopathy.
Topics: Adolescent; Brain Diseases; Brain Edema; Cerebral Hemorrhage; Child; Cockayne Syndrome; Dexamethason | 1981 |
[Hypertensive emergencies].
Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies; | 1974 |
Hypertensive encephalopathy.
Topics: Anxiety; Brain Diseases; Brain Edema; Coma; Diazoxide; Female; Furosemide; Glomerulonephritis; Heada | 1972 |