diazoxide has been researched along with Brain Disorders in 22 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It is concluded that a gradual fall in BP can be obtained after fractionated dosage of diazoxide (i." | 6.66 | Severe hypertension with cerebral symptoms treated with furosemide, fractionated diazoxide or dihydralazine. Danish Multicenter Study. ( Hilden, T; Krogsgaard, AR; McNair, A; Nielsen, PE, 1986) |
| " It is concluded that a gradual fall in BP can be obtained after fractionated dosage of diazoxide (i." | 2.66 | Severe hypertension with cerebral symptoms treated with furosemide, fractionated diazoxide or dihydralazine. Danish Multicenter Study. ( Hilden, T; Krogsgaard, AR; McNair, A; Nielsen, PE, 1986) |
| "Intracranial hypertension is a complication of hypertensive encephalopathy and may contribute to cerebral injury." | 1.26 | Intracranial pressure monitoring in severe hypertensive encephalopathy. ( Griswold, WR; James, HE; Mendoza, SA; Viney, J, 1981) |
| "Hypertensive encephalopathy is a dramatic syndrome characterized by severe elevation of blood pressure, headache, visual disturbances, altered mental status, and convulsions." | 1.26 | Hypertensive encephalopathy: recognition and management. ( Ram, CV, 1978) |
| "The hypertensive encephalopathy is a syndrome consisting of a sudden elevation of arterial pressure usually preceded by severe headache and followed by convulsions, coma or a variety of transitory cerebral phenomena." | 1.26 | Management of hypertensive encephalopathy. ( Finnerty, FA, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (95.45) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lang-Lazdunski, L | 1 |
| Heurteaux, C | 1 |
| Lazdunski, M | 1 |
| Vaziri, ND | 1 |
| Ram, CV | 4 |
| Griswold, WR | 1 |
| Viney, J | 1 |
| Mendoza, SA | 1 |
| James, HE | 1 |
| Grossman, SH | 1 |
| Gunnells, JC | 1 |
| Romankiewicz, JA | 1 |
| Becker, CE | 1 |
| Benowitz, NL | 1 |
| Finnerty, FA | 3 |
| Lowenthal, DT | 1 |
| Schalekamp, MA | 1 |
| Man In 'T Veld, AJ | 1 |
| Wenting, GJ | 1 |
| Verhoeven, RP | 1 |
| de Bruyn, JH | 1 |
| Pascual, AV | 1 |
| McNair, A | 2 |
| Krogsgaard, AR | 2 |
| Hilden, T | 2 |
| Nielsen, PE | 2 |
| Meese, RB | 1 |
| Fernandes, M | 1 |
| Kim, KE | 1 |
| Moyer, JH | 1 |
| Acchiardo, SR | 1 |
| Black, WD | 1 |
| Britt, L | 1 |
| McKeown, JW | 1 |
| Johnson, JG | 1 |
| Hatch, F | 1 |
8 reviews available for diazoxide and Brain Disorders
| Article | Year |
|---|---|
Malignant or accelerated hypertension.
Topics: Blood Coagulation Disorders; Brain Diseases; Diazoxide; Glomerulosclerosis, Focal Segmental; Humans; | 1984 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1984 |
Recognition and treatment of hypertensive emergencies.
Topics: Anticoagulants; Brain Diseases; Cerebrovascular Disorders; Coronary Disease; Diagnosis, Differential | 1981 |
Hypertensive emergencies: recognition and management.
Topics: Acute Disease; Aortic Aneurysm; Aortic Dissection; Brain Diseases; Cerebral Hemorrhage; Coronary Dis | 1982 |
Pharmacology and clinical use of drugs in hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Aorta; Brain Diseases; Cerebral Hemorrhage; Diazox | 1977 |
How to manage hypertensive emergencies and urgencies.
Topics: Adult; Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxid | 1976 |
Hypertensive cardiovascular emergencies.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1985 |
Hypertensive emergencies.
Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume | 1974 |
3 trials available for diazoxide and Brain Disorders
| Article | Year |
|---|---|
Cerebral symptoms and blood pressure during parenteral administration of chlorpromazine, dihydralazine and diazoxide. Danish multicenter study on acute severe hypertension.
Topics: Blood Pressure; Brain Diseases; Brain Ischemia; Chlorpromazine; Clinical Trials as Topic; Diazoxide; | 1983 |
Severe hypertension with cerebral symptoms treated with furosemide, fractionated diazoxide or dihydralazine. Danish Multicenter Study.
Topics: Adult; Aged; Antihypertensive Agents; Brain Diseases; Clinical Trials as Topic; Diazoxide; Dihydrala | 1986 |
Reversibility of cerebral symptoms in severe hypertension in relation to acute antihypertensive therapy. Danish Multicenter Study.
Topics: Aged; Antihypertensive Agents; Brain Diseases; Clinical Trials as Topic; Diazoxide; Dihydralazine; D | 1986 |
11 other studies available for diazoxide and Brain Disorders
| Article | Year |
|---|---|
Diazoxide for cerebral protection during deep hypothermic circulatory arrest: is it really safe?
Topics: Brain; Brain Diseases; Diazoxide; Heart Arrest, Induced; Humans; Ischemic Preconditioning | 2002 |
Intracranial pressure monitoring in severe hypertensive encephalopathy.
Topics: Adolescent; Brain Diseases; Brain Edema; Cerebral Hemorrhage; Child; Cockayne Syndrome; Dexamethason | 1981 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases | 1979 |
Hypertensive encephalopathy.
Topics: Antihypertensive Agents; Brain Diseases; Diazoxide; Humans; Hypertension; Nitroprusside | 1979 |
Hypertensive encephalopathy: recognition and management.
Topics: Brain Diseases; Diagnosis, Differential; Diazoxide; Humans; Hypertension; Nitroprusside; Trimethapha | 1978 |
Management of hypertensive encephalopathy.
Topics: Brain Diseases; Cerebrovascular Disorders; Diagnosis, Differential; Diazoxide; Humans; Hypertension; | 1978 |
Hypertensive crisis and postcrisis management.
Topics: Antihypertensive Agents; Brain Diseases; Diazoxide; Glomerular Filtration Rate; Hemodynamics; Humans | 1978 |
Hypertensive emergencies.
Topics: Antihypertensive Agents; Blood Pressure; Brain Diseases; Diazoxide; Dihydralazine; Emergencies; Huma | 1977 |
Aggressive drug therapy in accelerated hypertension.
Topics: Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxide; Ferr | 1974 |
Experience with hemodialysis and renal transplantation in patients with malignant hypertension.
Topics: Acute Kidney Injury; Adult; Brain Diseases; Diazoxide; Diet Therapy; Female; Follow-Up Studies; Furo | 1974 |
Hypertensive encephalopathy.
Topics: Anxiety; Brain Diseases; Brain Edema; Coma; Diazoxide; Female; Furosemide; Glomerulonephritis; Heada | 1972 |