diazoxide has been researched along with Brain Damage, Chronic in 2 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Initial interventions for hyperinsulinemia are conservative." | 2.41 | When it is more than transient neonatal hypoglycemia: hyperinsulinemia--a case study challenge. ( Shirland, L, 2001) |
| "Pretreatment with diazoxide resulted in significant improvement in both clinical neurologic scores and histopathology in our model of HCA." | 1.31 | Pharmacologically induced preconditioning with diazoxide: a novel approach to brain protection. ( Baumgartner, WA; Gott, VL; Johnston, MV; Marban, E; Peck, EA; Redmond, JM; Shake, JG; Troncoso, JC, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shirland, L | 1 |
| Shake, JG | 1 |
| Peck, EA | 1 |
| Marban, E | 1 |
| Gott, VL | 1 |
| Johnston, MV | 1 |
| Troncoso, JC | 1 |
| Redmond, JM | 1 |
| Baumgartner, WA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use for Diazoxide in the Initial Management of Hypoglycemia in Infants of Diabetic Mothers and Infants Large for Gestation[NCT00994149] | Phase 2/Phase 3 | 100 participants (Anticipated) | Interventional | 2009-10-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for diazoxide and Brain Damage, Chronic
| Article | Year |
|---|---|
When it is more than transient neonatal hypoglycemia: hyperinsulinemia--a case study challenge.
Topics: Blood Glucose; Brain Damage, Chronic; Diagnosis, Differential; Diazoxide; Enteral Nutrition; Female; | 2001 |
1 other study available for diazoxide and Brain Damage, Chronic
| Article | Year |
|---|---|
Pharmacologically induced preconditioning with diazoxide: a novel approach to brain protection.
Topics: Animals; Brain; Brain Damage, Chronic; Cell Survival; Cerebral Infarction; Diazoxide; Dogs; Heart Ar | 2001 |