diazoxide has been researched along with Astrocytosis in 3 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazoxide is a putative mitochondrial, ATP-sensitive potassium channel opener that has been implicated in neuroprotection in cerebral ischemia." | 3.73 | Post-ischemic administration of diazoxide attenuates long-term microglial activation in the rat brain after permanent carotid artery occlusion. ( Bari, F; Domoki, F; Farkas, E; Luiten, PG; Mihály, A; Timmer, NM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Nogradi, B | 1 |
| Meszlenyi, V | 1 |
| Patai, R | 1 |
| Polgar, TF | 1 |
| Spisak, K | 1 |
| Kristof, R | 1 |
| Siklos, L | 1 |
| Chen, M | 1 |
| Dong, Y | 1 |
| Simard, JM | 1 |
| Farkas, E | 1 |
| Timmer, NM | 1 |
| Domoki, F | 1 |
| Mihály, A | 1 |
| Luiten, PG | 1 |
| Bari, F | 1 |
3 other studies available for diazoxide and Astrocytosis
| Article | Year |
|---|---|
Diazoxide blocks or reduces microgliosis when applied prior or subsequent to motor neuron injury in mice.
Topics: Animals; Brain Stem; Diazoxide; Drug Administration Schedule; Facial Nucleus; Gliosis; Male; Mice; M | 2020 |
Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain.
Topics: Adenosine Triphosphate; Animals; Antibodies; Astrocytes; ATP-Binding Cassette Transporters; Binding, | 2003 |
Post-ischemic administration of diazoxide attenuates long-term microglial activation in the rat brain after permanent carotid artery occlusion.
Topics: Animals; Brain Infarction; Brain Ischemia; Carotid Stenosis; CD11 Antigens; Cerebrovascular Circulat | 2005 |