diazoxide has been researched along with Apoplexy in 4 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combined hemorrhagic shock (Shock) and unilateral common carotid artery occlusion (Stroke) results in a decrease of oxygen availability to peripheral tissues and organs and the central nervous system (CNS)." | 5.34 | Diazoxide, as a postconditioning and delayed preconditioning trigger, increases HSP25 and HSP70 in the central nervous system following combined cerebral stroke and hemorrhagic shock. ( Alam, H; McCabe, JT; O'Sullivan, JC; Yao, XL, 2007) |
| "Combined hemorrhagic shock (Shock) and unilateral common carotid artery occlusion (Stroke) results in a decrease of oxygen availability to peripheral tissues and organs and the central nervous system (CNS)." | 1.34 | Diazoxide, as a postconditioning and delayed preconditioning trigger, increases HSP25 and HSP70 in the central nervous system following combined cerebral stroke and hemorrhagic shock. ( Alam, H; McCabe, JT; O'Sullivan, JC; Yao, XL, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shimizu, K | 1 |
| Lacza, Z | 1 |
| Rajapakse, N | 1 |
| Horiguchi, T | 1 |
| Snipes, J | 1 |
| Busija, DW | 1 |
| Blanco, M | 1 |
| Lizasoain, I | 1 |
| Sobrino, T | 1 |
| Vivancos, J | 1 |
| Castillo, J | 1 |
| O'Sullivan, JC | 2 |
| Yao, XL | 1 |
| Alam, H | 1 |
| McCabe, JT | 2 |
| Fu, D | 1 |
| Alam, HB | 1 |
4 other studies available for diazoxide and Apoplexy
| Article | Year |
|---|---|
MitoK(ATP) opener, diazoxide, reduces neuronal damage after middle cerebral artery occlusion in the rat.
Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Diazoxide; Infarction, Middle | 2002 |
Ischemic preconditioning: a novel target for neuroprotective therapy.
Topics: Adenosine Triphosphate; alpha-Linolenic Acid; Animals; Brain; Brain Ischemia; Clinical Trials as Top | 2006 |
Diazoxide, as a postconditioning and delayed preconditioning trigger, increases HSP25 and HSP70 in the central nervous system following combined cerebral stroke and hemorrhagic shock.
Topics: Animals; Blood Pressure; Blotting, Western; Central Nervous System; Cerebral Cortex; Cerebral Hemorr | 2007 |
Diazoxide increases liver and kidney HSP25 and HSP70 after shock and stroke.
Topics: Animals; Diazoxide; Disease Models, Animal; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 He | 2008 |