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diazoxide and Anoxia, Brain

diazoxide has been researched along with Anoxia, Brain in 8 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Research Excerpts

ExcerptRelevanceReference
"Diazoxide pretreatment limited neurologic injury versus HCA alone, reflected in a preserved NAA:Cho ratio (1."1.33Noninvasive assessment of brain injury in a canine model of hypothermic circulatory arrest using magnetic resonance spectroscopy. ( Barker, PB; Barreiro, CJ; Baumgartner, WA; Blue, ME; Degaonkar, M; Fitton, TP; Gott, VL; Johnston, MV; Kratz, L; Lange, MS; Troncoso, JC; Williams, JA, 2006)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's4 (50.00)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Geiseler, SJ1
Ludvigsen, S1
Folkow, LP1
Barreiro, CJ1
Williams, JA1
Fitton, TP1
Lange, MS1
Blue, ME1
Kratz, L1
Barker, PB1
Degaonkar, M1
Gott, VL1
Troncoso, JC1
Johnston, MV1
Baumgartner, WA1
Liu, RG1
Wang, WJ1
Song, N1
Chen, YQ1
Li, LH1
Mattia, D1
Nagao, T1
Rogawski, MA1
Avoli, M1
Mironov, SL1
Langohr, K1
Haller, M1
Richter, DW1
Garcia de Arriba, S1
Franke, H1
Pissarek, M1
Nieber, K1
Illes, P1
Ben-Ari, Y2
Krnjević, K1

Other Studies

8 other studies available for diazoxide and Anoxia, Brain

ArticleYear
KATP-channels play a minor role in the protective hypoxic shut-down of cerebellar activity in eider ducks (Somateria mollissima).
    Neuroscience, 2015, Jan-22, Volume: 284

    Topics: Animals; Avian Proteins; Cerebellum; Diazoxide; Ducks; Female; Hypoxia, Brain; KATP Channels; Male;

2015
Noninvasive assessment of brain injury in a canine model of hypothermic circulatory arrest using magnetic resonance spectroscopy.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:5

    Topics: Animals; Aspartic Acid; Cardiopulmonary Bypass; Cerebellum; Cerebral Cortex; Choline; Circulatory Ar

2006
Diazoxide preconditioning plus subsequent hypothermia increased resistance of rat cultured hippocampal neurons against hypoxia-reoxygenation injury.
    Chinese medical journal, 2006, Jun-05, Volume: 119, Issue:11

    Topics: Animals; Calcium; Cell Survival; Cells, Cultured; Diazoxide; Female; Hippocampus; Hypothermia, Induc

2006
Potassium channel activators counteract anoxic hyperexcitability but not 4-aminopyridine-induced epileptiform activity in the rat hippocampal slice.
    Neuropharmacology, 1994, Volume: 33, Issue:12

    Topics: 4-Aminopyridine; Animals; Benzopyrans; Cromakalim; Diazoxide; Epilepsy; Hippocampus; Hypoxia, Brain;

1994
Hypoxia activates ATP-dependent potassium channels in inspiratory neurones of neonatal mice.
    The Journal of physiology, 1998, Jun-15, Volume: 509 ( Pt 3)

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Calcium; Diazoxide; Electric Stimulation; Glyburi

1998
Neuroprotection by ATP-dependent potassium channels in rat neocortical brain slices during hypoxia.
    Neuroscience letters, 1999, Sep-24, Volume: 273, Issue:1

    Topics: Animals; ATP-Binding Cassette Transporters; Diazoxide; Hypoglycemic Agents; Hypoxia, Brain; Ion Chan

1999
Modulation of ATP sensitive K+ channels: a novel strategy to reduce the deleterious effects of anoxia.
    Advances in experimental medicine and biology, 1990, Volume: 268

    Topics: Adenosine Triphosphate; Animals; Diazoxide; Galanin; Glutamates; Glutamic Acid; Glyburide; Hippocamp

1990
Anoxic changes in dentate granule cells.
    Neuroscience letters, 1989, Dec-15, Volume: 107, Issue:1-3

    Topics: Animals; Diazoxide; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Membrane Potentials; Potassium

1989