Page last updated: 2024-10-25

diazoxide and Aging

diazoxide has been researched along with Aging in 11 studies

Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's2 (18.18)18.2507
2000's5 (45.45)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, X1
Duan, P1
Hu, X1
Li, R1
Zhu, Q1
Capel, F1
Prod'homme, M1
Béchet, D1
Taillandier, D1
Balage, M1
Attaix, D1
Combaret, L1
Headrick, JP1
Willems, L1
Ashton, KJ1
Holmgren, K1
Peart, J1
Matherne, GP1
McCully, JD1
Toyoda, Y1
Wakiyama, H1
Rousou, AJ1
Parker, RA1
Levitsky, S1
Basabe, JC1
Pivetta, OH1
de Bruno, LF1
Cresto, JC1
Aparicio, NJ1
Williams, AJ1
Beales, PE1
Krug, J1
Procaccini, E1
Signore, A1
Xu, S1
Gale, EA1
Pozzilli, P1
Jahangir, A1
Ozcan, C1
Holmuhamedov, EL1
Terzic, A1
Schulman, D1
Latchman, DS1
Yellon, DM1
Rane, A1
Wilson, JT1
Uno, H1
Irion, GL1
Vasthare, US1
Tuma, RF1

Reviews

1 review available for diazoxide and Aging

ArticleYear
Quantitative models for the study of hair growth in vivo.
    Annals of the New York Academy of Sciences, 1991, Dec-26, Volume: 642

    Topics: Aging; Alopecia; Animals; Diazoxide; DNA Replication; Hair; Humans; Macaca; Minoxidil; Models, Biolo

1991

Other Studies

10 other studies available for diazoxide and Aging

ArticleYear
Altered KATP Channel Subunits Expression and Vascular Reactivity in Spontaneously Hypertensive Rats With Age.
    Journal of cardiovascular pharmacology, 2016, Volume: 68, Issue:2

    Topics: Age Factors; Aging; Animals; Aorta; Blood Pressure; Diazoxide; Disease Models, Animal; Dose-Response

2016
Lysosomal and proteasome-dependent proteolysis are differentially regulated by insulin and/or amino acids following feeding in young, mature and old rats.
    The Journal of nutritional biochemistry, 2009, Volume: 20, Issue:8

    Topics: Aging; Amino Acids; Amino Acids, Branched-Chain; Animals; Diazoxide; Diet, Protein-Restricted; Dieta

2009
Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression.
    The Journal of physiology, 2003, Jun-15, Volume: 549, Issue:Pt 3

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Aging; Alkaloids; Animals; Arrhythmias, Cardiac; Benzo

2003
Age- and gender-related differences in ischemia/reperfusion injury and cardioprotection: effects of diazoxide.
    The Annals of thoracic surgery, 2006, Volume: 82, Issue:1

    Topics: Aging; Animals; Cardioplegic Solutions; Cardiotonic Agents; Cerebral Infarction; Diazoxide; Disease

2006
A temporal study of somatostatin secretion and its inhibitory effect in genetically diabetic mice (C57BL/KsJ-db/db).
    Endocrinology, 1983, Volume: 113, Issue:6

    Topics: Aging; Animals; Diabetes Mellitus; Diazoxide; Glucose; In Vitro Techniques; Insulin; Insulin Secreti

1983
Tolbutamide reduces the incidence of diabetes mellitus, but not insulitis, in the non-obese-diabetic mouse.
    Diabetologia, 1993, Volume: 36, Issue:6

    Topics: Aging; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diazoxide; Female; Insulin; Islets of Lang

1993
Increased calcium vulnerability of senescent cardiac mitochondria: protective role for a mitochondrial potassium channel opener.
    Mechanisms of ageing and development, 2001, Jul-31, Volume: 122, Issue:10

    Topics: Aging; Animals; Calcium; Diazoxide; Ion Channel Gating; Mitochondria, Heart; Myocardium; Oxidation-R

2001
Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:4

    Topics: Adenosine; Aging; Animals; Diazoxide; Diglycerides; Heart; Ischemic Preconditioning, Myocardial; Mal

2001
Clinical pharmacokinetics in infants and children.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:1

    Topics: Aging; Body Water; Carbamazepine; Child; Child, Preschool; Clindamycin; Dextropropoxyphene; Diazoxid

1976
Age-related change in skeletal muscle blood flow in the rat.
    Journal of gerontology, 1987, Volume: 42, Issue:6

    Topics: Aging; Animals; Blood Flow Velocity; Diazoxide; Female; Hemodynamics; Male; Muscle Contraction; Musc

1987