diazoxide has been researched along with Acute Disease in 30 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty patients with blood pressure over 180/110 mm Hg one hour after admission to a coronary care unit with recent acute myocardial infarction were given intravenous diazoxide in a bolus of 300 mg." | 7.65 | Intravenous diazoxide in treatment of hypertension associated with recent myocardial infarction. ( Grigor, RR; O'Brien, KP; Taylor, PM, 1975) |
| "Twenty-six patients with hypertension secondary to acute poststreptococcal glomerulonephritis were treated by the rapid intravenous infusion of diazoxide." | 7.65 | Intravenous diazoxide in acute poststreptococcal glomerulonephritis. ( Hill, LL; Kohaut, EC; Wilson, CJ, 1975) |
| "Treatment with oral diazoxide for periods of 4 to 10 weeks in hospital allowed adequate control of hypertension with continuation of fetal growth in four patients with severe toxaemia." | 7.65 | Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy. ( Davis, D; Morgan, MY; Pohl, JE; Thurston, H, 1972) |
| "Five patients suffering from familial periodic paralysis with hypokalemia (FPP) were exposed to standard paralysis induction trials which elicited total paralyysis and hypokalemia." | 6.64 | Trial of the prophylactic effect of diazoxide in the treatment of familial periodic hypokalemia. ( Johnsen, T, 1977) |
| "Diazoxide was given orally to nine hypertensive patients with renal failure and its effect on blood pressure and on glucose metabolism was studied." | 5.25 | Oral diazoxide contraindicated in severe hypertension with renal failure. ( Belpaire, FM; De Broe, ME; Mussche, MM; Ringoir, SM; Vermeulen, A, 1975) |
| "Twenty patients with blood pressure over 180/110 mm Hg one hour after admission to a coronary care unit with recent acute myocardial infarction were given intravenous diazoxide in a bolus of 300 mg." | 3.65 | Intravenous diazoxide in treatment of hypertension associated with recent myocardial infarction. ( Grigor, RR; O'Brien, KP; Taylor, PM, 1975) |
| "Twenty-six patients with hypertension secondary to acute poststreptococcal glomerulonephritis were treated by the rapid intravenous infusion of diazoxide." | 3.65 | Intravenous diazoxide in acute poststreptococcal glomerulonephritis. ( Hill, LL; Kohaut, EC; Wilson, CJ, 1975) |
| "Treatment with oral diazoxide for periods of 4 to 10 weeks in hospital allowed adequate control of hypertension with continuation of fetal growth in four patients with severe toxaemia." | 3.65 | Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy. ( Davis, D; Morgan, MY; Pohl, JE; Thurston, H, 1972) |
| "Five patients suffering from familial periodic paralysis with hypokalemia (FPP) were exposed to standard paralysis induction trials which elicited total paralyysis and hypokalemia." | 2.64 | Trial of the prophylactic effect of diazoxide in the treatment of familial periodic hypokalemia. ( Johnsen, T, 1977) |
| "Cause of renal disease are chronic renal failure in three, acute renal failure in three, hemolytic uremic syndrome in two, acute post streptococcal glomerulonephritis in one, and renal arterial stenosis in a further patient." | 1.26 | [Hypertensive emergencies in children with renal hypertension (author's transl)]. ( Bachmann, HJ; Olbing, H; Pistor, K, 1979) |
| "Diazoxide was given orally to nine hypertensive patients with renal failure and its effect on blood pressure and on glucose metabolism was studied." | 1.25 | Oral diazoxide contraindicated in severe hypertension with renal failure. ( Belpaire, FM; De Broe, ME; Mussche, MM; Ringoir, SM; Vermeulen, A, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (96.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moodley, J | 1 |
| Brandt, D | 2 |
| Ram, CV | 1 |
| Flatau, E | 1 |
| Kaufman, N | 1 |
| Kohn, D | 1 |
| Martínez P Mendaña, J | 1 |
| Hernández García, JM | 1 |
| Bralo Ron, MT | 1 |
| Gozalo F Lomana, MI | 1 |
| de la Fuente, P | 1 |
| Bender, F | 1 |
| Rahgozar, M | 1 |
| Pazokitoroudi, H | 1 |
| Bakhtiarian, A | 1 |
| Djahanguiri, B | 1 |
| Johnsen, T | 1 |
| Retzke, U | 1 |
| Schwarz, R | 1 |
| Lauckner, W | 1 |
| Rahn, KH | 1 |
| Duraković, Z | 1 |
| Bakran, V | 1 |
| Vrhovac, B | 1 |
| Gjurasin, M | 1 |
| Bachmann, HJ | 1 |
| Olbing, H | 1 |
| Pistor, K | 1 |
| Mussche, MM | 1 |
| De Broe, ME | 1 |
| Belpaire, FM | 1 |
| Vermeulen, A | 1 |
| Ringoir, SM | 1 |
| Watt, JB | 1 |
| Mroczek, WJ | 1 |
| Haas, Th | 1 |
| Denkl, P | 1 |
| Fleischmann, LE | 1 |
| Kumar, GK | 1 |
| Dastoor, FC | 1 |
| Robayo, JR | 1 |
| Razzaque, MA | 1 |
| Leibovici, H | 1 |
| Boner, G | 1 |
| Grunstein, S | 1 |
| Anderman, S | 1 |
| Diekmann, L | 1 |
| Curry, CL | 1 |
| O'Brien, KP | 1 |
| Grigor, RR | 1 |
| Taylor, PM | 1 |
| Kohaut, EC | 1 |
| Wilson, CJ | 1 |
| Hill, LL | 1 |
| Onoe, K | 1 |
| Kobashi, K | 1 |
| Fujinaka, S | 1 |
| Yamamoto, T | 1 |
| Hamajo, T | 1 |
| Finnerty, FA | 1 |
| Rawlins, MD | 1 |
| Pennington, JC | 1 |
| Picker, RH | 1 |
| Michael, CA | 1 |
| Pohl, JE | 1 |
| Thurston, H | 1 |
| Davis, D | 1 |
| Morgan, MY | 1 |
5 reviews available for diazoxide and Acute Disease
| Article | Year |
|---|---|
The management of hypertension in pregnancy: A review.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anesthesia, Epidural; Anesthesia, Obstetrical; Anticoagu | 1980 |
[Therapy of hypertensive crisis].
Topics: Acute Disease; Bed Rest; Cardiac Glycosides; Clonidine; Diazoxide; Dihydralazine; Diuretics; Heart F | 1980 |
Hypertensive emergencies: recognition and management.
Topics: Acute Disease; Aortic Aneurysm; Aortic Dissection; Brain Diseases; Cerebral Hemorrhage; Coronary Dis | 1982 |
[Hypoglycemia and its countermeasures].
Topics: Acute Disease; Adenoma, Islet Cell; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Animals; Bloo | 1969 |
Variability in response to drugs.
Topics: Acute Disease; Acylation; Chlorthalidone; Chronic Disease; Depression; Diazoxide; Digoxin; Dose-Resp | 1974 |
1 trial available for diazoxide and Acute Disease
| Article | Year |
|---|---|
Trial of the prophylactic effect of diazoxide in the treatment of familial periodic hypokalemia.
Topics: Acute Disease; Blood Glucose; Clinical Trials as Topic; Diazoxide; Drug Evaluation; Drug Resistance; | 1977 |
24 other studies available for diazoxide and Acute Disease
| Article | Year |
|---|---|
[The hypertensive crisis].
Topics: Acute Disease; Calcium Channel Blockers; Clonidine; Coronary Disease; Diazoxide; Dihydralazine; Dilt | 1984 |
[Slow infusion of diazoxide for hypertensive crisis].
Topics: Acute Disease; Aged; Diazoxide; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged | 1981 |
[Treatment of acute hypertension during labor with diazoxide. Fetal repercussions].
Topics: Acute Disease; Adult; Blood Pressure; Diazoxide; Female; Fetus; Humans; Hypertension; Injections, In | 1980 |
Acute hypertensive crises.
Topics: Acute Disease; Adult; Aged; Clonidine; Diazoxide; Heart Block; Humans; Hypertension; Injections, Int | 1980 |
Diazoxide, a K(ATP) opener, accelerates restitution of ethanol or indomethacin-induced gastric ulceration in rats independent of polyamines.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diazoxide; Ethanol; Glyburide; Indo | 2001 |
[The haemodynamic principle of action of diazoxide (hypertonalum) in the treatment of acute hypertensive crises in late pregnant women (author's transl)].
Topics: Acute Disease; Cardiac Output; Diazoxide; Eclampsia; Female; Heart Rate; Humans; Hypertension; Pregn | 1979 |
[Therapy of hypertensive crisis].
Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine | 1977 |
[Diazoxide and furosemide in the treatment of hypertensive emergencies (author's transl)].
Topics: Acute Disease; Adult; Aged; Diazoxide; Drug Therapy, Combination; Female; Furosemide; Humans; Hypert | 1978 |
[Hypertensive emergencies in children with renal hypertension (author's transl)].
Topics: Acute Disease; Acute Kidney Injury; Child; Child, Preschool; Diazoxide; Female; Glomerulonephritis; | 1979 |
Oral diazoxide contraindicated in severe hypertension with renal failure.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Blood Glucose; Diabetic Ketoacidosis; Diazoxide; F | 1975 |
Treatment for hypertensive crisis.
Topics: Acute Disease; Diazoxide; Hypertension; Myocardial Infarction | 1977 |
[Therapy of hypertensive crises].
Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine | 1977 |
Management of hypertensive crisis in children.
Topics: Acute Disease; Adolescent; Cerebrovascular Disorders; Child; Child, Preschool; Diazoxide; Humans; Hy | 1977 |
Side effects of diazoxide.
Topics: Acute Disease; Diazoxide; Female; Hemiplegia; Humans; Hypertension; Hypotension; Injections, Intrave | 1976 |
[Diazoxide in severe hypertension during pregnancy].
Topics: Acute Disease; Diazoxide; Female; Humans; Pre-Eclampsia; Pregnancy | 1976 |
[The acute crisis of blood pressure and its treatment in childhood (authors transl)].
Topics: Acute Disease; Acute Kidney Injury; Administration, Oral; Adolescent; Age Factors; Child; Diazoxide; | 1975 |
Current treatment of malignant hypertension.
Topics: Acute Disease; Administration, Oral; Antihypertensive Agents; Blood Pressure; Diazoxide; Diuretics; | 1975 |
Intravenous diazoxide in treatment of hypertension associated with recent myocardial infarction.
Topics: Acute Disease; Aged; Blood Pressure; Diazoxide; Electrocardiography; Female; Heart Rate; Humans; Hyp | 1975 |
Intravenous diazoxide in acute poststreptococcal glomerulonephritis.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Diazoxide; Drug Evaluation; Glomerulonephritis; | 1975 |
Hypertensive crisis.
Topics: Acute Disease; Cerebrovascular Circulation; Cerebrovascular Disorders; Diagnosis, Differential; Diaz | 1974 |
Diazoxide and the treatment of the acute hypertensive emergency in obstetrics.
Topics: Acute Disease; Adolescent; Adult; Diazoxide; Eclampsia; Emergencies; Female; Humans; Hypertension; I | 1972 |
Diazoxide and the treatment of the acute hypertensive emergency in obstetrics.
Topics: Acute Disease; Diazoxide; Female; Humans; Hypertension; Obstetric Labor Complications; Pregnancy | 1972 |
Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy.
Topics: Acute Disease; Administration, Oral; Adult; Albuminuria; Blood Glucose; Diazoxide; Female; Furosemid | 1972 |
Emergency reduction of blood pressure.
Topics: Acute Disease; Antihypertensive Agents; Diazoxide; Ferricyanides; Humans; Hydralazine; Injections, I | 1971 |