diazoxide has been researched along with Acute Brain Injuries in 6 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Obesity is associated with increased infarct volumes and adverse outcomes following ischemic stroke." | 5.40 | Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels. ( Chen, Y; Fang, X; Jiang, Y; Xu, J; Yang, Z; Zhang, Y, 2014) |
| "Spasms were well controlled with high-dose prednisolone therapy." | 1.72 | Case Report: Neurodevelopmental Outcome in a Small-for-Gestational-Age Infant With Symptomatic Hyperinsulinemic Hypoglycemia, Gaze Preference, and Infantile Spasms. ( Chandran, S; Janardhan, K; Teoh, KW; Yap, F, 2022) |
| "Obesity is associated with increased infarct volumes and adverse outcomes following ischemic stroke." | 1.40 | Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels. ( Chen, Y; Fang, X; Jiang, Y; Xu, J; Yang, Z; Zhang, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chandran, S | 1 |
| Teoh, KW | 1 |
| Janardhan, K | 1 |
| Yap, F | 1 |
| Budinich, CS | 1 |
| Tucker, LB | 1 |
| Lowe, D | 1 |
| Rosenberger, JG | 1 |
| McCabe, JT | 1 |
| Yang, Z | 1 |
| Chen, Y | 1 |
| Zhang, Y | 1 |
| Jiang, Y | 1 |
| Fang, X | 1 |
| Xu, J | 1 |
| Wu, H | 1 |
| Wang, P | 1 |
| Li, Y | 1 |
| Wu, M | 1 |
| Lin, J | 1 |
| Huang, Z | 1 |
| Chen, M | 1 |
| Dong, Y | 1 |
| Simard, JM | 1 |
| He, X | 1 |
| Mo, X | 1 |
| Gu, H | 1 |
| Chen, F | 1 |
| Gu, Q | 1 |
| Peng, W | 1 |
| Qi, J | 1 |
| Shen, L | 1 |
| Sun, J | 1 |
| Zhang, R | 1 |
| Kj, Y | 1 |
6 other studies available for diazoxide and Acute Brain Injuries
| Article | Year |
|---|---|
Case Report: Neurodevelopmental Outcome in a Small-for-Gestational-Age Infant With Symptomatic Hyperinsulinemic Hypoglycemia, Gaze Preference, and Infantile Spasms.
Topics: Blood Glucose; Brain Injuries; Child; Congenital Hyperinsulinism; Diazoxide; Glucose; Humans; Hypogl | 2022 |
Short and long-term motor and behavioral effects of diazoxide and dimethyl sulfoxide administration in the mouse after traumatic brain injury.
Topics: Animals; Behavior, Animal; Brain Injuries; Diazoxide; Dimethyl Sulfoxide; Male; Maze Learning; Mice; | 2013 |
Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels.
Topics: Animals; Body Weight; Brain; Brain Injuries; Brain Ischemia; Decanoic Acids; Diazoxide; Diet, High-F | 2014 |
Diazoxide Attenuates Postresuscitation Brain Injury in a Rat Model of Asphyxial Cardiac Arrest by Opening Mitochondrial ATP-Sensitive Potassium Channels.
Topics: Animals; Asphyxia; Brain Injuries; Cerebral Cortex; Diazoxide; Disease Models, Animal; Heart Arrest; | 2016 |
Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain.
Topics: Adenosine Triphosphate; Animals; Antibodies; Astrocytes; ATP-Binding Cassette Transporters; Binding, | 2003 |
Neuroprotective effect of diazoxide on brain injury induced by cerebral ischemia/reperfusion during deep hypothermia.
Topics: Analysis of Variance; Animals; Brain Injuries; Caspase 3; Cerebrovascular Circulation; Cytochromes c | 2008 |