diaziquone has been researched along with Glioma in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (77.27) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bedikian, AY; Benjamin, RS; Burgess, MA; Feun, LG; Fields, WS; Leavens, ME; Obbens, EA; Savaraj, N; Stewart, DJ; Yung, WK | 1 |
| Bjornsson, TD; Falletta, JM; Friedman, HS; Schold, SC | 1 |
| Cooke, C; Ellis, JR; Kornblith, PL; McKeever, PE; Oberc-Greenwood, MA; Smith, BH | 1 |
| Collins, JM; Curt, GA; Kelley, JA; Kornblith, PL; Kufta, CV; Smith, BH; Young, RC | 1 |
| Bachur, NR; Bellis, EH; Collins, JM; Egorin, MJ; Salcman, M; Spiegel, JF | 1 |
| Bigner, DD; Bjornsson, TD; Friedman, HS; Schold, SC | 1 |
| Feola, J; Houchens, DP; Ovejera, AA; Slagel, DE | 1 |
| Archibald, YM; Barr, HW; Cairncross, JG; Del Maestro, RF; Fisher, BJ; Gaspar, LE; Lunn, D; Macdonald, DR; Pexman, JH; Ruttan, LA | 1 |
| Dowling, S; Gaspar, L; Halperin, EC; Herndon, J; Imperato, J; Salter, M | 1 |
| Bigner, DD; Burger, PC; Cairncross, JG; Dropcho, EJ; Halperin, EC; Herndon, JE; Macdonald, DR; Morawetz, R; Schold, SC; Vick, NA | 1 |
| George, SL; Peterson, BL; Potthoff, RF | 1 |
| Darling, JL; Thomas, DG | 1 |
| Coleman, RE; Djang, WT; Falletta, JM; Friedman, HS; Halperin, EC; Kurtzberg, J; Longee, DC; Oakes, WJ; Schold, SC | 1 |
| Bruner, JM; Feun, LG; Harris, MI; Yung, WK | 1 |
| Ali-Osman, F; Dougherty, D; Giblin, J; Rosenblum, ML | 1 |
| Al Sarraf, M; Austin, D; Decker, DA; Kresge, C; Wilner, HI | 1 |
| Al-Sarraf, M; Ensley, J; Kish, J; Tapazoglou, E | 1 |
| Allen, JC; Bloom, J; Ertel, I; Evans, A; Hammond, D; Jenkin, D; Jones, H; Levin, V; Sposto, R; Wara, W | 1 |
| Bona, JD; Edwards, JA; Hawkins, C; Hirschfeld, A; Kornblith, PL; Matuzic, N; Rosa, L | 1 |
| Erexson, GL; Kligerman, AD; Schold, SC; Wilmer, JL | 1 |
| Grillo-Lopez, AJ; Jacquillat, C; Maral, J; Mashaly, P; Pertuiset, BF; Poisson, M; Weil, M | 1 |
1 review(s) available for diaziquone and Glioma
| Article | Year |
|---|---|
Brain tumors in children: current cooperative and institutional chemotherapy trials in newly diagnosed and recurrent disease.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Glioma; Humans; Medulloblastoma; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Nitrosourea Compounds | 1986 |
4 trial(s) available for diaziquone and Glioma
| Article | Year |
|---|---|
An analysis of radiotherapy data from the CNS cancer consortium's randomized prospective trial comparing AZQ to BCNU in the treatment of patients with primary malignant brain tumors. The CNS cancer consortium.
Topics: Adult; Aged; Aged, 80 and over; Astrocytoma; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Oligodendroglioma; Radiography; Radiotherapy Dosage; Survival Analysis | 1993 |
Randomized comparison of diaziquone and carmustine in the treatment of adults with anaplastic glioma.
Topics: Adult; Analysis of Variance; Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Male; Middle Aged; Proportional Hazards Models; Survival Analysis | 1993 |
Brain tumors in children: current cooperative and institutional chemotherapy trials in newly diagnosed and recurrent disease.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Glioma; Humans; Medulloblastoma; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Nitrosourea Compounds | 1986 |
Sister chromatid exchange induction in patients with anaplastic gliomas undergoing treatment with radiation plus diaziquone or 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Lymphocytes; Male; Radiation, Ionizing; Sister Chromatid Exchange; Time Factors | 1987 |
18 other study(ies) available for diaziquone and Glioma
| Article | Year |
|---|---|
A phase II trial of 2,5,-diaziridinyl 3,6-bis (carboethoxy amino) 1,4-benzoquinone (AZQ, NSC 182986) in recurrent primary brain tumors.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Astrocytoma; Aziridines; Azirines; Benzoquinones; Bone Marrow Diseases; Brain Neoplasms; Drug Evaluation; Glioblastoma; Glioma; Humans; Middle Aged; Neoplasm Recurrence, Local | 1984 |
Treatment of patients with recurrent primary brain tumors with AZQ.
Topics: Adolescent; Adult; Aged; Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Cerebellar Neoplasms; Child; Child, Preschool; Ependymoma; Female; Glioma; Humans; Male; Medulloblastoma; Middle Aged | 1984 |
Mitochondrial toxicity of 2,5-diaziridinyl-3,6-bis-(carboethoxyamino)-1,4-benzoquinone.
Topics: Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Cell Line; Cell Nucleus; Chromatin; Endoplasmic Reticulum; Glioma; Humans; Microscopy, Electron; Mitochondria; Time Factors | 1983 |
Phase II and pharmacokinetic study of aziridinylbenzoquinone [2,5-diaziridinyl-3,6-bis(carboethoxyamino)-1,4-benzoquinone, diaziquone, NSC 182986] in high-grade gliomas.
Topics: Adult; Aged; Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Blood-Brain Barrier; Brain Neoplasms; Drug Evaluation; Female; Glioma; Humans; Kinetics; Male; Middle Aged | 1983 |
The pharmacology of diaziquone given in intravenous or intracarotid infusion to normal and intracranial tumor-bearing puppies.
Topics: Animals; Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Carotid Arteries; Dogs; Glioma; Infusions, Parenteral; Kinetics | 1984 |
Treatment of human glioma and medulloblastoma tumor lines in athymic mice with diaziquone and diaziquone-based drug combinations.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Cell Division; Cell Line; Drug Evaluation, Preclinical; Glioma; Humans; Medulloblastoma; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous | 1984 |
Combined modality treatment using radiation and/or chemotherapy in an athymic nude mouse-human medulloblastoma and glioblastoma xenograft model.
Topics: Animals; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cell Line; Glioma; Humans; Medulloblastoma; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Procarbazine; Time Factors; Transplantation, Heterologous | 1982 |
Cognitive functioning in long-term survivors of high-grade glioma.
Topics: Adult; Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cognition; Female; Glioma; Humans; Male; Middle Aged; Neuropsychological Tests; Pilot Projects | 1994 |
Detecting treatment-by-centre interaction in multi-centre clinical trials.
Topics: Aged; Antineoplastic Agents, Alkylating; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Computer Simulation; Glioma; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Remission Induction; Statistics as Topic | 2001 |
Response of short-term cultures derived from human malignant glioma to aziridinylbenzoquinone, etoposide and doxorubicin: an in vitro phase II trial.
Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Glioma; Humans; Tumor Cells, Cultured | 2001 |
Criteria for termination of phase II chemotherapy for patients with progressive or recurrent brain tumor.
Topics: Adolescent; Antineoplastic Agents; Astrocytoma; Aziridines; Benzoquinones; Brain Neoplasms; Cohort Studies; Drug Therapy, Combination; Glioma; Humans; Lomustine; Male; Neoplasm Recurrence, Local; Procarbazine; Tomography, Emission-Computed; Tomography, X-Ray Computed | 1989 |
Intravenous BCNU and AZQ in patients with recurrent malignant gliomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Female; Glioma; Humans; Injections, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local | 1989 |
Application of in vivo and in vitro pharmacokinetics for physiologically relevant drug exposure in a human tumor clonogenic cell assay.
Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Biological Assay; Brain Neoplasms; Carmustine; Cell Line; Cisplatin; Clone Cells; Dose-Response Relationship, Drug; Ellipticines; Glioma; Half-Life; Humans; Mathematics; Streptozocin; Teniposide | 1987 |
Phase II study of aziridinylbenzoquinone (AZQ: NSC-182986) in the treatment of malignant gliomas recurrent after radiation. Preliminary report.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Astrocytoma; Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Evaluation; Female; Follow-Up Studies; Glioblastoma; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Oligodendroglioma | 1985 |
Response rate and toxicity with aziridinylbenzoquinone in patients with recurrent gliomas. A progress report.
Topics: Adolescent; Adult; Aged; Anemia; Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Drug Evaluation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Neoplasm Recurrence, Local; Thrombocytopenia; Vomiting | 1988 |
Response variability of human brain tumors to AZQ in tissue culture.
Topics: Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Cell Line; Culture Techniques; Dose-Response Relationship, Drug; Glioma; Humans | 1986 |
Effect of AZQ (1,4-cyclohexadiene-1,4-diacarbamic acid-2,5-bis(1-aziridinyl)-3,6 -dioxodiethylester) in recurring supratentorial malignant brain gliomas--a Phase II study. EORTC Brain Tumour Cooperative Group.
Topics: Adult; Aged; Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Brain Neoplasms; Drug Evaluation; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local | 1985 |
Phase II evaluation of diaziquone (CI-904, AZQ) in the treatment of human malignant glioma.
Topics: Adult; Aged; Aziridines; Azirines; Benzoquinones; Blood-Brain Barrier; Brain Neoplasms; Combined Modality Therapy; Drug Evaluation; Female; Glioma; Humans; Male; Middle Aged | 1985 |