diazinon and Glioma
diazinon has been researched along with Glioma in 2 studies
Diazinon: A cholinesterase inhibitor that is used as an organothiophosphorus insecticide.
diazinon : A member of the class of pyrimidines that is pyrimidine carrying an isopropyl group at position 2, a methyl group at position 6 and a (diethoxyphosphorothioyl)oxy group at position 4.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to evaluate the toxicity of diazinon oxon (DZO), a major in vivo metabolite of the organophosphate insecticide diazinon (DZ), on differentiating rat C6 glioma cells." | 7.75 | Diazinon oxon interferes with differentiation of rat C6 glioma cells. ( Flaskos, J; Hargreaves, AJ; Harris, W; Sachana, M; Sidiropoulou, E; Woldehiwet, Z, 2009) |
| "In previous work, the outgrowth of axon-like processes by differentiating mouse N2a neuroblastoma cells was shown to be inhibited by exposure to 10 microM diazinon." | 7.75 | Neuroprotection from diazinon-induced toxicity in differentiating murine N2a neuroblastoma cells. ( Flaskos, J; Hargreaves, AJ; Harris, W; Sachana, M, 2009) |
| "The purpose of this study was to evaluate the toxicity of diazinon oxon (DZO), a major in vivo metabolite of the organophosphate insecticide diazinon (DZ), on differentiating rat C6 glioma cells." | 3.75 | Diazinon oxon interferes with differentiation of rat C6 glioma cells. ( Flaskos, J; Hargreaves, AJ; Harris, W; Sachana, M; Sidiropoulou, E; Woldehiwet, Z, 2009) |
| "In previous work, the outgrowth of axon-like processes by differentiating mouse N2a neuroblastoma cells was shown to be inhibited by exposure to 10 microM diazinon." | 3.75 | Neuroprotection from diazinon-induced toxicity in differentiating murine N2a neuroblastoma cells. ( Flaskos, J; Hargreaves, AJ; Harris, W; Sachana, M, 2009) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Sidiropoulou, E | 1 |
| Sachana, M | 2 |
| Flaskos, J | 2 |
| Harris, W | 2 |
| Hargreaves, AJ | 2 |
| Woldehiwet, Z | 1 |
Other Studies
2 other studies available for diazinon and Glioma
| Article | Year |
|---|---|
Diazinon oxon interferes with differentiation of rat C6 glioma cells.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cholinesterase Inhibitors; Diazinon; Dose-Response | 2009 |
Neuroprotection from diazinon-induced toxicity in differentiating murine N2a neuroblastoma cells.
Topics: Analysis of Variance; Animals; Antibodies; Axons; Cell Differentiation; Cholinesterase Inhibitors; C | 2009 |