Page last updated: 2024-10-25

diazepam and Thrombosis

diazepam has been researched along with Thrombosis in 11 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Research Excerpts

ExcerptRelevanceReference
" In the present study, the rCBF changes and microthrombosis formation were investigated in a cortical contusional model in rats, and the effects of etizolam (platelet activating factor antagonist) on microthrombosis were tested."3.69Hemodynamic depression and microthrombosis in the peripheral areas of cortical contusion in the rat: role of platelet activating factor. ( Aoyama, N; Katayama, Y; Kawamata, T; Maeda, T; Mori, T, 1997)
"The significant occurrence of thrombophlebitis in patients administered diazepam intravenously was described recently."3.66Poloxamer 188 as vehicle for injectable diazepam. ( Bernardoni, RJ; Ecanow, B; Prancan, AV; Sadove, MS, 1980)
" By utilizing the drugs discussed and titrating the dosage to the needs of the patient, intravenous sedation will last long enough to complete the selected periodontal surgical procedure."1.25Intravenous sedation of the periodontal surgical patient. ( Ruggerio, AC, 1975)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19909 (81.82)18.7374
1990's1 (9.09)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greifzu, F1
Pielecka-Fortuna, J1
Kalogeraki, E1
Krempler, K1
Favaro, PD1
Schlüter, OM1
Löwel, S1
Prancan, AV1
Ecanow, B1
Bernardoni, RJ1
Sadove, MS1
Maeda, T1
Katayama, Y1
Kawamata, T1
Aoyama, N1
Mori, T1
Kessler, HJ1
Patschke, D1
Palieri Furlan, L1
Cappa, AP1
Prot, N1
Margaria, E1
Lovera, C1
Ruggerio, AC1
Warkany, J1
Tassinari, CA1
Roger, J1
Dravat, C1
Gustaut, H1
Galletly, DC1
Wilson, LF1
Treuren, BC1
Boon, BP1
Padfield, A1
Schneider, S1
Mace, JW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Relationship Between Lipid Peroxidation Products From Traumatic Brain Injury and Secondary Coagulation Disorders[NCT04274777]100 participants (Anticipated)Observational2019-09-21Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for diazepam and Thrombosis

ArticleYear
Diazepam mixed micelle--comparison with diazepam in propylene glycol and midazolam.
    Anaesthesia and intensive care, 1985, Volume: 13, Issue:4

    Topics: Benzodiazepines; Blood Pressure; Diazepam; Female; Heart Rate; Humans; Micelles; Midazolam; Pain; Ph

1985

Other Studies

10 other studies available for diazepam and Thrombosis

ArticleYear
Environmental enrichment extends ocular dominance plasticity into adulthood and protects from stroke-induced impairments of plasticity.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jan-21, Volume: 111, Issue:3

    Topics: Animals; Diazepam; Dominance, Ocular; Environment; Female; GABA Modulators; Ibuprofen; Interneurons;

2014
Poloxamer 188 as vehicle for injectable diazepam.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:8

    Topics: Animals; Diazepam; Injections; Male; Necrosis; Pharmaceutical Vehicles; Poloxalene; Polyethylene Gly

1980
Hemodynamic depression and microthrombosis in the peripheral areas of cortical contusion in the rat: role of platelet activating factor.
    Acta neurochirurgica. Supplement, 1997, Volume: 70

    Topics: Animals; Brain Concussion; Cerebral Cortex; Cerebrovascular Circulation; Diazepam; Hemodynamics; Mal

1997
[Histamine H2-receptor blockade and thrombosis prophylaxis with heparin in tetanus. A case report (author's transl)].
    Der Anaesthesist, 1978, Volume: 27, Issue:8

    Topics: Ampicillin; Baclofen; Cimetidine; Diazepam; Heparin; Histamine H2 Antagonists; Humans; Male; Middle

1978
[Possibility of damage to blood vessel walls due to intravenous anesthetics. Clinical and experimental study].
    Minerva anestesiologica, 1979, Volume: 45, Issue:4

    Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Anesthetics; Animals; Atropine; Blood

1979
Intravenous sedation of the periodontal surgical patient.
    Journal of periodontology, 1975, Volume: 46, Issue:6

    Topics: Anesthesia, Dental; Anesthesia, Intravenous; Blood Pressure; Diazepam; Hematoma; Histamine; Humans;

1975
A warfarin embryopathy?
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:3

    Topics: Abnormalities, Drug-Induced; Alcoholism; Chondrodysplasia Punctata; Diazepam; Digitalis Glycosides;

1975
Letter: Comments on a startling article: "loss of limb following intravenous diazepam".
    Pediatrics, 1975, Volume: 55, Issue:6

    Topics: Amputation, Surgical; Arm; Benzodiazepines; Diazepam; Epilepsy; Humans; Injections, Intra-Arterial;

1975
Letter: Thromobosis following diazepam.
    British journal of anaesthesia, 1974, Volume: 46, Issue:6

    Topics: Diazepam; Humans; Injections, Intravenous; Thrombophlebitis; Thrombosis

1974
Loss of limb following intravenous diazepam.
    Pediatrics, 1974, Volume: 53, Issue:1

    Topics: Arm; Child, Preschool; Diazepam; Epilepsy; Hand; Humans; Injections, Intra-Arterial; Injections, Int

1974