Page last updated: 2024-10-25

diazepam and Spinal Diseases

diazepam has been researched along with Spinal Diseases in 9 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Spinal Diseases: Diseases involving the SPINE.

Research Excerpts

ExcerptRelevanceReference
"In a double-blind trial tizanidine (DS 103-282: 5-Chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole), a new muscle relaxant, was compared with diazepam in twenty in-patients suffering from acute paravertebral muscle spasm."9.05Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam. ( Fryda-Kaurimsky, Z; Müller-Fassbender, H, 1981)
"In a double-blind trial tizanidine (DS 103-282: 5-Chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole), a new muscle relaxant, was compared with diazepam in twenty in-patients suffering from acute paravertebral muscle spasm."5.05Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam. ( Fryda-Kaurimsky, Z; Müller-Fassbender, H, 1981)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KOENIGSTEIN, RP1
KRAMMER, H1
Fryda-Kaurimsky, Z1
Müller-Fassbender, H1
Johnson, BA1
Schellhas, KP1
Pollei, SR1
Burke, DJ1
Ma, LH1
Hu, SL1
Brogden, RN1
Speight, TM1
Avery, GS1
Baumgartner, H1
Grimmeisen, H1
Paeslack, V1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase III, Multicenter, Randomized Study to Assess the Efficacy and Safety of 0,5 mg Tizaspray® Administered Intranasally Versus Sirdalud® 2 mg Tablets, in Patients With Acute Low Back Pain[NCT02934061]Phase 3117 participants (Actual)Interventional2016-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for diazepam and Spinal Diseases

ArticleYear
Baclofen: a preliminary report of its pharmacological properties and therapeutic efficacy in spasticity.
    Drugs, 1974, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aminobutyrates; Animals; Chlorobenzenes; Chronic Disease; Clinical Trials as Topi

1974
[Drug and physical therapy of vertebral syndromes].
    Wiener medizinische Wochenschrift (1946), 1974, Dec-21, Volume: 124, Issue:51-52

    Topics: Anesthetics, Local; Anti-Inflammatory Agents; Balneology; Bandages; Cryotherapy; Diazepam; Electric

1974

Trials

2 trials available for diazepam and Spinal Diseases

ArticleYear
Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam.
    The Journal of international medical research, 1981, Volume: 9, Issue:6

    Topics: Acute Disease; Adult; Back Pain; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method;

1981
Baclofen: a preliminary report of its pharmacological properties and therapeutic efficacy in spasticity.
    Drugs, 1974, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aminobutyrates; Animals; Chlorobenzenes; Chronic Disease; Clinical Trials as Topi

1974

Other Studies

6 other studies available for diazepam and Spinal Diseases

ArticleYear
[ON THE DIAGNOSIS AND THERAPY OF MYOGENIC PAIN IN DEGENERATIVE CHANGES OF THE SPINE IN GERIATRICS].
    Wiener klinische Wochenschrift, 1964, Nov-27, Volume: 76

    Topics: Diazepam; Geriatrics; Humans; Muscle Cramp; Pain; Spinal Diseases

1964
Epidurography and therapeutic epidural injections: technical considerations and experience with 5334 cases.
    AJNR. American journal of neuroradiology, 1999, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Back Pain; Conscious Sedation; Contrast

1999
An approach to the treatment of spasticity.
    Drugs, 1975, Volume: 10, Issue:2

    Topics: Adrenergic alpha-Antagonists; Baclofen; Brain Diseases; Dantrolene; Diazepam; Humans; Mephenesin; Mu

1975
[An application of acupuncture anesthesia to cervical vertebral canal procedures].
    Zhen ci yan jiu = Acupuncture research, 1987, Volume: 12, Issue:3

    Topics: Acupuncture Therapy; Adult; Aged; Anesthesia; Cervical Vertebrae; Diazepam; Droperidol; Female; Huma

1987
[Possibilities and limitations of therapy with valium].
    Die Medizinische Welt, 1968, Dec-21, Volume: 51

    Topics: Diazepam; Humans; Preanesthetic Medication; Respiratory Insufficiency; Spinal Diseases

1968
[Drug therapy of spinal spasms].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1965, Volume: 71

    Topics: Adolescent; Adult; Diazepam; Female; Humans; Male; Middle Aged; Muscle Spasticity; Paraplegia; Spina

1965