Page last updated: 2024-10-25

diazepam and Spasm

diazepam has been researched along with Spasm in 115 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"In a double-blind trial tizanidine (DS 103-282: 5-Chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole), a new muscle relaxant, was compared with diazepam in twenty in-patients suffering from acute paravertebral muscle spasm."9.05Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam. ( Fryda-Kaurimsky, Z; Müller-Fassbender, H, 1981)
"In this study, we determined the efficacy of two novel neurosteroids, pregnanolone glutamate (PAG) and pregnanolone pyroglutamate (PPG), and tested these drugs in doses of 1-10 mg/kg (ip) against the TMDT syndrome and in our rodent model of infantile spasms."8.31Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms. ( Chern, CJ; Chern, CR; Chodounská, H; Kudová, E; Lauková, M; Schonwald, A; Shakarjian, MP; Velíšek, L; Velíšková, J, 2023)
" We describe a case of severe back pain resistant to parenteral morphine accompanied by muscle spasm, in which the addition of diazepam both had an opioid-sparing effect and provided superior symptomatic relief."7.72Diazepam as an adjuvant analgesic to morphine for pain due to skeletal muscle spasm. ( Srivastava, M; Walsh, D, 2003)
"A case of severe muscle spasms relieved by oral administration of dantrolene sodium is presented."7.67Treatment of muscle spasms with oral dantrolene sodium. ( Christian, JM, 1989)
"In a double-blind trial tizanidine (DS 103-282: 5-Chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole), a new muscle relaxant, was compared with diazepam in twenty in-patients suffering from acute paravertebral muscle spasm."5.05Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam. ( Fryda-Kaurimsky, Z; Müller-Fassbender, H, 1981)
" Analysis of 13 patients with stiff-man syndrome examined at the Mayo Clinic during the past 30 years revealed that treatment with diazepam decreased the muscle spasms."4.77Stiff-man syndrome updated. ( Howard, FM; Lorish, TR; Thorsteinsson, G, 1989)
"In this study, we determined the efficacy of two novel neurosteroids, pregnanolone glutamate (PAG) and pregnanolone pyroglutamate (PPG), and tested these drugs in doses of 1-10 mg/kg (ip) against the TMDT syndrome and in our rodent model of infantile spasms."4.31Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms. ( Chern, CJ; Chern, CR; Chodounská, H; Kudová, E; Lauková, M; Schonwald, A; Shakarjian, MP; Velíšek, L; Velíšková, J, 2023)
" We describe a case of severe back pain resistant to parenteral morphine accompanied by muscle spasm, in which the addition of diazepam both had an opioid-sparing effect and provided superior symptomatic relief."3.72Diazepam as an adjuvant analgesic to morphine for pain due to skeletal muscle spasm. ( Srivastava, M; Walsh, D, 2003)
" For management of postoperative muscle spasm, an intravenous benzodiazepine was used (diazepam 0."3.69Pain management for children following selective dorsal rhizotomy. ( Geiduschek, JM; Haberkern, CM; Hays, RM; Jacobson, LE; McLaughlin, JF; Roberts, TS, 1994)
"A case of severe muscle spasms relieved by oral administration of dantrolene sodium is presented."3.67Treatment of muscle spasms with oral dantrolene sodium. ( Christian, JM, 1989)
"It is characterized by muscle spasms triggered by startle, voluntary movement, or tactile or emotional stimuli, occurring predominantly in the axial musculature."1.37Stiff person syndrome and pregnancy. ( Blaskiewicz, R; Goldkamp, J; Myles, T, 2011)
"Treatment with diazepam ameliorated the spasms, while treatment with the sodium channel antagonist MS-222 ameliorated both spasms and body curvature, suggesting that pyrethroid-induced neurotoxicity is similar in zebrafish and mammals."1.36Developmental neurotoxicity of pyrethroid insecticides in zebrafish embryos. ( Cooper, KR; DeMicco, A; Richardson, JR; White, LA, 2010)
"Treatment with diazepam led to resolution of spasticity, whereas repeated courses of intravenous immunoglobulin improved cerebellar function, including appendicular ataxia and downbeating nystagmus."1.33Downbeating nystagmus and muscle spasms in a patient with glutamic-acid decarboxylase antibodies. ( Ances, BM; Dalmau, JO; Galetta, SL; Hasbani, MJ; Tsai, J, 2005)
"Tubal spasm was encountered in 37 cases (9."1.27Incidence, significance and remission of tubal spasm during attempted hysteroscopic tubal sterilization. ( Aiken, M; Cooper, JM; Houck, R; Rigberg, HS, 1985)
"Pressure sore are caused by multiple mechanisms."1.26Pressure ulcerations. ( Elliott, TM, 1982)
"A female patient had permanent axial muscular rigidity similar to the "stiff-man syndrome", together with axial myoclonus triggered by stretch reflexes and by supramaximal stimulation of the supraorbital nerve."1.26Jerking stiff-man syndrome. ( Alberca, R; Chaparro, J; Romero, M, 1982)

Research

Studies (115)

TimeframeStudies, this research(%)All Research%
pre-199099 (86.09)18.7374
1990's5 (4.35)18.2507
2000's4 (3.48)29.6817
2010's5 (4.35)24.3611
2020's2 (1.74)2.80

Authors

AuthorsStudies
Chern, CR3
Lauková, M3
Schonwald, A3
Kudová, E3
Chodounská, H3
Chern, CJ3
Shakarjian, MP3
Velíšková, J3
Velíšek, L3
Shen, D1
Zhou, H1
Chen, S1
DeMicco, A1
Cooper, KR1
Richardson, JR1
White, LA1
Mathew, PJ1
Samra, T1
Wig, J1
Goldkamp, J1
Blaskiewicz, R1
Myles, T1
Jacob, J1
Tarabar, AF1
Rodrigo, C1
Samarakoon, L1
Fernando, SD1
Rajapakse, S1
Bonev, VI1
Gledhill, RF1
Srivastava, M1
Walsh, D1
OLAFSON, RA1
MULDER, DW1
HOWARD, FM2
CARTER, CH2
BRUMAGNE, J1
TARPLEY, EL1
CIBEIRA, JB1
BUZZI, A1
DOMINELLI, JC1
MCGIVNEY, JQ1
CLEVELAND, BR1
MORIARTY, J1
BERTOLOTTI, L1
SCHLAEPFER, U1
MUMENTHALER, M1
PERNIKOFF, M1
Ances, BM1
Dalmau, JO1
Tsai, J1
Hasbani, MJ1
Galetta, SL1
Ng, CL1
Little, SC1
Johnson, BK1
Anhalt, MA1
Chastain, DE1
Fryda-Kaurimsky, Z1
Müller-Fassbender, H1
Meinck, HM1
Ricker, K2
Conrad, B1
Francis, DA1
Elliott, TM1
DeLisa, JA1
Little, J1
Alberca, R1
Romero, M1
Chaparro, J1
Morris, HH1
Whelan, JL1
Strauss, A1
Geiduschek, JM1
Haberkern, CM1
McLaughlin, JF1
Jacobson, LE1
Hays, RM1
Roberts, TS1
Tin, LN1
Elalaoui, MY1
Akula, E1
Gilbertson, AA1
Rechlin, R1
Rossberg, B1
Reinschke, P1
Gudowski, G1
Donaldson, D1
Gibson, G1
Burke, DJ1
Westblom, U1
Ahmad, S1
Meeran, MK1
Scheiner, JJ1
Raz, S1
Smith, RB1
Verrier, M2
Ashby, P2
MacLEOD, S2
Gordon, DH1
Levin, DC1
From, A1
Heltberg, A1
Calne, DB1
Berman, W1
Schmidt, RT2
Stahl, SM1
Spehlmann, R2
Lee, RH1
Goonewardene, TW1
Sentheshanmuganathan, S1
Kamalanathan, S1
Kanagasunderam, R1
Sienkiewicz, R1
Rózewicki, S1
Lorish, TR1
Thorsteinsson, G1
Christian, JM1
Moldovanu, IV1
Chubar', AV1
Chuchin, MIu1
Cooper, JM1
Rigberg, HS1
Houck, R1
Aiken, M1
White, C1
Richens, A1
Slaffer, SN1
Parsonage, M1
Palaja, J1
Montserrat, L1
Merino, A1
Mertens, HG1
Hartmann-von Monakow, K1
Lazar, M1
Pedersen, E1
Serratrice, G1
Roux, H1
Aquaron, R1
de Bisschop, G1
Dubois-Gambarelli, D1
Jobin, JP1
Chyatte, SB1
Basmajian, JV1
Glass, A1
Hannah, A1
Sakabe, T1
Vassa, NT1
Doshi, HV1
Yajnik, VH1
Shah, SS1
Joshi, KR1
Patel, SH1
Praestholm, J1
Lester, J1
Ketelaer, P1
Tyberghein, JM1
Ketelaer, CJ1
Haase, J1
Jepsen, BV1
Bech, H1
Langeback, E1
Counahan, R1
Oduori, ML1
Nothmann, BJ1
Schuster, MM1
Cartlidge, NE1
Hudgson, P1
Weightman, D1
Domino, EF1
Dundee, JW1
Haslett, WH1
Diemath, HE1
Enge, S1
Lechner, H1
Coulter, C1
Edmunds, J1
Pyle, PO1
Zbinden, G1
Randall, LO1
Henriksen, PB1
Ayim, EN1
Bianchine, JR1
Bianchine, JW1
Lenman, JA1
Bennett, JV1
Heitmann, R1
Peirson, GA1
Fowlks, EW1
King, PS1
Wheatley, D1
Wilson, LA2
McKechnie, AA1
Gozon, F1
Cordova, AB1
Stoebner, RC1
Kiser, RW1
Decherd, JF1
Perry, JE1
Höök, O1
Landin, S1
Goto, K1
Carlson, KE2
Alston, W2
Couvée, LM1
van der Laarse, WD1
Oosterveld, WJ1
Fukushima, Y1
Akihama, Y1
Shibuki, K1
Sato, A1
Heidrich, H1
Ibe, K1
Klinge, D1
Evine, IM1
Jossmann, PB1
Friend, DG1
DeAngelis, V1
Kane, M1
Kendall, PH1
Rushworth, G1
Neill, RW1
Simpson, CA1
Tridon, P1
Weber, M1
Thiriet, M1
Matthews, WB1
Diamantis, W1
Kletzkin, M1
Sie, KL1
Blom, PS1
Goor, C1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase III, Multicenter, Randomized Study to Assess the Efficacy and Safety of 0,5 mg Tizaspray® Administered Intranasally Versus Sirdalud® 2 mg Tablets, in Patients With Acute Low Back Pain[NCT02934061]Phase 3117 participants (Actual)Interventional2016-10-31Completed
Botulinum Toxin Urethral Sphincter Injection for Dysfunctional Voiding - A Multicenter Study, Randomized, Double-Blind, Placebo Control[NCT01733290]Phase 270 participants (Actual)Interventional2012-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for diazepam and Spasm

ArticleYear
A meta-analysis of magnesium for tetanus.
    Anaesthesia, 2012, Volume: 67, Issue:12

    Topics: Anticonvulsants; Diazepam; Female; Humans; Magnesium Sulfate; Male; Randomized Controlled Trials as

2012
Levator ani syndrome - a case study and literature review.
    Australian family physician, 2007, Volume: 36, Issue:6

    Topics: Acetaminophen; Adult; Anal Canal; Analgesics, Non-Narcotic; Anus Diseases; Baths; Diazepam; Family P

2007
[Problems of juvenile poisoning (Ingestion accidents)].
    Zeitschrift fur arztliche Fortbildung, 1978, Oct-15, Volume: 72, Issue:20

    Topics: Aftercare; Anti-Bacterial Agents; Antidotes; Burns, Chemical; Child; Child, Preschool; Diazepam; Exc

1978
Drug treatment of spasticity and rigidity.
    Modern trends in neurology, 1975, Volume: 6

    Topics: Amantadine; Baclofen; Diazepam; Humans; Levodopa; Mephenesin; Muscle Rigidity; Parasympatholytics; P

1975
Stiff-man syndrome updated.
    Mayo Clinic proceedings, 1989, Volume: 64, Issue:6

    Topics: Adult; Diagnosis, Differential; Diazepam; Electromyography; Female; Gait; Humans; Lordosis; Male; Mi

1989
Clinical assessment and pharmacologic therapy of spasticity.
    Archives of physical medicine and rehabilitation, 1974, Volume: 55, Issue:8

    Topics: Achilles Tendon; Activities of Daily Living; Curare; Dantrolene; Diazepam; Electromyography; Gait; H

1974
[Central effect of local anesthetics].
    Masui. The Japanese journal of anesthesiology, 1974, Volume: 23, Issue:12

    Topics: Anesthetics, Local; Animals; Brain; Diazepam; Dogs; Electroencephalography; Lidocaine; Spasm

1974
The benzodiazepines. A review of their actions and uses relative to anaesthetic practice.
    British journal of anaesthesia, 1970, Volume: 42, Issue:3

    Topics: Amnesia; Anesthesia; Anesthesia, Intravenous; Anesthesia, Obstetrical; Anticonvulsants; Benzazepines

1970
Pharmacology of benzodiazepines: laboratory and clinical correlations.
    Advances in pharmacology, 1967, Volume: 5

    Topics: Aggression; Alcoholism; Animals; Anticonvulsants; Anxiety; Autonomic Nervous System; Avoidance Learn

1967

Trials

14 trials available for diazepam and Spasm

ArticleYear
Magnesium sulphate for treatment of tetanus in adults.
    Anaesthesia and intensive care, 2010, Volume: 38, Issue:1

    Topics: Adult; Aged; Autonomic Nervous System Diseases; Cohort Studies; Diazepam; Disease Progression; Femal

2010
Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam.
    The Journal of international medical research, 1981, Volume: 9, Issue:6

    Topics: Acute Disease; Adult; Back Pain; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method;

1981
Muscle relaxants: chlorzoxazone compared with diazepam (a double-blind study).
    Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Benzoxazoles; Chlorzoxazone; Clinical Trials as Topic; Diazepam; Female; Humans;

1976
A double-blind trial with baclofen (Lioresal) and diazepam in spasticity due to multiple sclerosis.
    Acta neurologica Scandinavica, 1975, Volume: 51, Issue:2

    Topics: Adult; Aged; Aminobutyrates; Chlorobenzenes; Clinical Trials as Topic; Diazepam; Drug Evaluation; Fe

1975
Letter: Thymoxamine and spasticity.
    Lancet (London, England), 1974, Volume: 1, Issue:7859

    Topics: Administration, Oral; Clinical Trials as Topic; Diazepam; Humans; Injections, Intravenous; Moxisylyt

1974
Diazepam in spasticity.
    Lancet (London, England), 1970, May-30, Volume: 1, Issue:7657

    Topics: Clinical Trials as Topic; Diazepam; Hemiplegia; Humans; Spasm

1970
Dantrolene sodium: long-term effects in severe spasticity.
    Archives of physical medicine and rehabilitation, 1973, Volume: 54, Issue:7

    Topics: Activities of Daily Living; Adolescent; Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Ce

1973
A comparison of dantrolene sodium and diazepam in the treatment of spasticity.
    Paraplegia, 1974, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Cerebrovascular Disorders; Clinical Trials as Topic; Dantrolene; Diazepam;

1974
Comparative clinical trial of diazepam with other conventional drugs in tetanus.
    Postgraduate medical journal, 1974, Volume: 50, Issue:590

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Drug Evaluation; Dru

1974
Evaluation of diazepam in skeletal muscle hypertonicity in cerebral palsy.
    Archives of physical medicine and rehabilitation, 1968, Volume: 49, Issue:9

    Topics: Adolescent; Adult; Athetosis; Cerebral Palsy; Child; Child, Preschool; Clinical Trials as Topic; Dia

1968
Acute treatment of epileptic seizures with diazepamum (Valium).
    Acta neurologica Scandinavica, 1967, Volume: 43, Issue:S31

    Topics: Acute Disease; Adolescent; Adult; Aged; Aphasia; Clinical Trials as Topic; Diazepam; Epilepsy; Epile

1967
Diazepam in musculo-skeletal spasm. Report on a G.P. Research Group trial.
    Annals of physical medicine, 1964, Volume: Suppl

    Topics: Adolescent; Adult; Aged; Aspirin; Child; Clinical Trials as Topic; Diazepam; Female; Fibromyalgia; H

1964
Oral diazepam in the treatment of spasticity in paraplegia a double-blind trial and subsequent impressions.
    Scottish medical journal, 1966, Volume: 11, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Middle Aged; Paraplegia; Spas

1966
Diazepam in the treatment of spasticity. A preliminary quantitative evaluation.
    Journal of chronic diseases, 1969, Volume: 22, Issue:1

    Topics: Adult; Diazepam; Electrodes; Electromyography; Female; Humans; Male; Middle Aged; Multiple Sclerosis

1969

Other Studies

92 other studies available for diazepam and Spasm

ArticleYear
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnan

2023
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnan

2023
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnan

2023
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnan

2023
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnan

2023
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnan

2023
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnan

2023
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnan

2023
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnan

2023
Spasms and Myoclonus in a Young Woman With Hashimoto Thyroiditis.
    JAMA neurology, 2020, 05-01, Volume: 77, Issue:5

    Topics: Adult; Anticonvulsants; Clonazepam; Diazepam; Encephalomyelitis; Female; Hashimoto Disease; Humans;

2020
Developmental neurotoxicity of pyrethroid insecticides in zebrafish embryos.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 113, Issue:1

    Topics: Abnormalities, Drug-Induced; Aminobenzoates; Animals; Biological Assay; Craniofacial Abnormalities;

2010
Stiff person syndrome and pregnancy.
    Obstetrics and gynecology, 2011, Volume: 118, Issue:2 Pt 2

    Topics: Adult; Amines; Baclofen; Cesarean Section; Cyclohexanecarboxylic Acids; Diazepam; Female; Gabapentin

2011
A rare case of combined strychnine and propoxur toxicity from a single preparation.
    Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:3

    Topics: Adult; Atropine; Charcoal; Diazepam; Drug Combinations; Gastric Lavage; Humans; Insecticides; Intuba

2012
Paroxysmal kinesigenic choreoathetosis because of cryptogenic myelitis. Remission with carbamazepine and the pathogenetic role of altered sodium channels.
    European journal of neurology, 2002, Volume: 9, Issue:5

    Topics: Adult; Anticonvulsants; Carbamazepine; Central Nervous System; Cervical Vertebrae; Chorea; Diazepam;

2002
Diazepam as an adjuvant analgesic to morphine for pain due to skeletal muscle spasm.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2003, Volume: 11, Issue:1

    Topics: Back Pain; Carcinoma, Renal Cell; Diazepam; Humans; Kidney Neoplasms; Lumbar Vertebrae; Male; Middle

2003
"STIFF-MAN" SYNDROME: A REVIEW OF THE LITERATURE, REPORT OF THREE ADDITIONAL CASES AND DISCUSSION OF PATHOPHYSIOLOGY AND THERAPY.
    Mayo Clinic proceedings, 1964, Volume: 39

    Topics: Diazepam; Electromyography; Geriatrics; Humans; Male; Muscular Diseases; Pathology; Spasm; Tranquili

1964
A CONTROLLED EVALUATION OF TWO BENZODIAZEPINE DERIVATES IN THE MANAGEMENT OF MENTALLY RETARDED, CEREBRAL-PALSIED PATIENTS.
    Medical times, 1964, Volume: 92

    Topics: Adolescent; Anticonvulsants; Athetosis; Benzodiazepines; Biomedical Research; Cerebral Palsy; Child;

1964
[DOUBLE BLIND TEST AND DECONTRACTANT THERAPY IN RHEUMATOLOGY].
    Revue medicale de Liege, 1964, Jul-15, Volume: 19

    Topics: Biomedical Research; Blindness; Chemistry, Pharmaceutical; Diazepam; Double-Blind Method; Geriatrics

1964
EVALUATION OF DIAZEPAM (VALIUM) IN THE SYMPTOMATIC TREATMENT OF RHEUMATIC DISORDERS. A CONTROLLED COMPARATIVE STUDY.
    Journal of chronic diseases, 1965, Volume: 18

    Topics: Anxiety; Arthritis; Arthritis, Rheumatoid; Biomedical Research; Carisoprodol; Chlormezanone; Diazepa

1965
[CLINICAL AND ELECTROMYOGRAPHIC STUDIES IN 110 PATIENTS TREATED WITH A BENZODIAZEPINE DERIVATIVE].
    Prensa medica argentina, 1964, Dec-25, Volume: 51

    Topics: Benzodiazepines; Diazepam; Drug Therapy; Electromyography; Humans; Muscle Spasticity; Paralysis; Spa

1964
THE LEVATOR SYNDROME AND ITS TREATMENT.
    Southern medical journal, 1965, Volume: 58

    Topics: Anus Diseases; Diazepam; Drug Therapy; Humans; Pain; Sacrococcygeal Region; Spasm

1965
CONTROL OF TETANIC SPASMS WITH DIAZEPAM: CASE REPORT OF SEVERE TETANUS.
    The Journal of the Medical Society of New Jersey, 1965, Volume: 62

    Topics: Diazepam; Drug Therapy; Humans; Spasm; Tetanus; Tetanus Toxoid

1965
[CLINICAL EXAMINATION OF THE MUSCLE RELAXANT EFFECT OF VALIUM "ROCHE" IN SPASTIC PATIENTS].
    Schweizerische medizinische Wochenschrift, 1964, Oct-03, Volume: 94

    Topics: Diazepam; Drug Therapy; Humans; Movement Disorders; Muscle Spasticity; Physical Examination; Spasm

1964
TREATMENT OF ACUTE AND CHRONIC MUSCLE SPASM WITH DIAZEPAM.
    Clinical medicine (Northfield, Ill.), 1964, Volume: 71

    Topics: Back Pain; Diazepam; Geriatrics; Humans; Muscle Cramp; Muscle Relaxants, Central; Myositis; Spasm; T

1964
Downbeating nystagmus and muscle spasms in a patient with glutamic-acid decarboxylase antibodies.
    American journal of ophthalmology, 2005, Volume: 140, Issue:1

    Topics: Autoantibodies; Diazepam; Diplopia; Drug Therapy, Combination; Female; Glutamate Decarboxylase; Huma

2005
The "stiff-man" syndrome. A report of two additional cases treated with diazepam.
    The Alabama journal of medical sciences, 1967, Volume: 4, Issue:4

    Topics: Adult; Diazepam; Humans; Male; Middle Aged; Muscular Diseases; Spasm

1967
The stiff-man syndrome: new pathophysiological aspects from abnormal exteroceptive reflexes and the response to clomipramine, clonidine, and tizanidine.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:3

    Topics: Adult; Brain Stem; Clomipramine; Clonidine; Diazepam; Electromyography; Female; Humans; Muscle Rigid

1984
Drugs to relieve spasticity.
    Drug and therapeutics bulletin, 1983, Jan-14, Volume: 21, Issue:1

    Topics: Baclofen; Dantrolene; Diazepam; Humans; Parasympatholytics; Spasm

1983
Benzodiazepines and spasmodic torticollis.
    Archives of neurology, 1983, Volume: 40, Issue:5

    Topics: Adult; Benzodiazepines; Diazepam; Humans; Male; Spasm; Torticollis

1983
Pressure ulcerations.
    American family physician, 1982, Volume: 25, Issue:2

    Topics: Blood Proteins; Contracture; Debridement; Diazepam; Humans; Hygiene; Ischemia; Patient Care Team; Pa

1982
Managing spasticity.
    American family physician, 1982, Volume: 26, Issue:3

    Topics: Adult; Baclofen; Child, Preschool; Cold Temperature; Dantrolene; Diazepam; Female; Humans; Muscle Sp

1982
Jerking stiff-man syndrome.
    Journal of neurology, neurosurgery, and psychiatry, 1982, Volume: 45, Issue:12

    Topics: Adult; Baclofen; Diazepam; Female; Humans; Muscle Rigidity; Myoclonus; Spasm

1982
Current treatment of status epilepticus.
    The Journal of family practice, 1981, Volume: 13, Issue:7

    Topics: Adult; Anticonvulsants; Child; Diagnosis, Differential; Diazepam; Humans; Hysteria; Injections, Intr

1981
Baclofen in treatment of the 'stiff-man' syndrome.
    Archives of neurology, 1980, Volume: 37, Issue:9

    Topics: Adult; Baclofen; Diazepam; Drug Therapy, Combination; Humans; Male; Muscle Rigidity; Spasm

1980
Altered responses to medications exposed to excessive temperatures during shipping.
    Southern medical journal, 1995, Volume: 88, Issue:6

    Topics: Chronic Disease; Diazepam; Drug Stability; Drug Storage; Female; Hot Temperature; Humans; Meperidine

1995
Pain management for children following selective dorsal rhizotomy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Bupiva

1994
Arterial spasm after administration of diazepam.
    British journal of anaesthesia, 1994, Volume: 72, Issue:1

    Topics: Adult; Diazepam; Female; Humans; Injections, Intravenous; Peripheral Vascular Diseases; Pregnancy; R

1994
Laryngeal spasm.
    British journal of anaesthesia, 1993, Volume: 71, Issue:1

    Topics: Anesthesia; Diazepam; Humans; Laryngeal Diseases; Spasm

1993
Local complications with intravenous diazepam.
    Journal (Canadian Dental Association), 1979, Volume: 45, Issue:7

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Arteries; Diazepam; Female; Humans; Injections, Intra-Ar

1979
An approach to the treatment of spasticity.
    Drugs, 1975, Volume: 10, Issue:2

    Topics: Adrenergic alpha-Antagonists; Baclofen; Brain Diseases; Dantrolene; Diazepam; Humans; Mephenesin; Mu

1975
Stiff-man syndrome and clonazepam.
    JAMA, 1977, May-02, Volume: 237, Issue:18

    Topics: Benzodiazepinones; Clonazepam; Diazepam; Female; Humans; Middle Aged; Muscle Rigidity; Spasm; Syndro

1977
Treatment of spasmodic torticollis with diazepam.
    British medical journal, 1979, Jan-13, Volume: 1, Issue:6156

    Topics: Adult; Diazepam; Female; Humans; Male; Spasm; Torticollis

1979
External sphincter spasticity syndrome in female patients.
    The Journal of urology, 1976, Volume: 115, Issue:4

    Topics: Adult; Diazepam; Female; Humans; Male; Methyldopa; Phenoxybenzamine; Spasm; Syndrome; Urethra; Ureth

1976
Effect of diazepam on muscle contraction in spasticity.
    American journal of physical medicine, 1976, Volume: 55, Issue:4

    Topics: Action Potentials; Adult; Aged; Diazepam; Female; Humans; Infusions, Parenteral; Leg; Male; Middle A

1976
Treatment of angiographically produced cord seizures by intra-arterial diazepam.
    Catheterization and cardiovascular diagnosis, 1976, Volume: 2, Issue:3

    Topics: Angiography; Celiac Artery; Contrast Media; Diazepam; Female; Humans; Iatrogenic Disease; Injections

1976
Letter: The ketogenic diet, West and Lennox syndromes.
    Developmental medicine and child neurology, 1975, Volume: 17, Issue:2

    Topics: Child; Child, Preschool; Clonazepam; Diazepam; Humans; Infant; Intellectual Disability; Myoclonus; N

1975
A pharmacologic study of the stiff-man syndrome. Correlation of clinical symptoms with urinary 3-methoxy-4-hydroxy-phenyl glycol excretion.
    Neurology, 1975, Volume: 25, Issue:7

    Topics: Diazepam; Glycine; Glycols; Homovanillic Acid; Humans; Levodopa; Male; Metanephrine; Methoxyhydroxyp

1975
The effect of diazepam on presynaptic inhibition in patients with complete and incomplete spinal cord lesions.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1975, Volume: 2, Issue:3

    Topics: Adult; Diazepam; Electric Stimulation; Female; H-Reflex; Humans; Male; Middle Aged; Multiple Scleros

1975
Treatment of spasticity in multiple sclerosis: comparison of dantrolene sodium and diazepam.
    Transactions of the American Neurological Association, 1975, Volume: 100

    Topics: Dantrolene; Diazepam; Humans; Hydantoins; Multiple Sclerosis; Spasm

1975
Accidental subarachnoid injection of gallamine. A case report.
    British journal of anaesthesia, 1975, Volume: 47, Issue:8

    Topics: Anesthesia, Spinal; Blood Pressure; Chromatography, Thin Layer; Dexamethasone; Diazepam; Gallamine T

1975
[Evaluation of combined application of diazepam, fenoterol and metamizole in prevention of uterine-tubal spasm during the performance of hysterosalpingography].
    Ginekologia polska, 1992, Volume: 63, Issue:10

    Topics: Diazepam; Dipyrone; Drug Therapy, Combination; Fallopian Tube Diseases; Fallopian Tube Patency Tests

1992
Treatment of muscle spasms with oral dantrolene sodium.
    Oral surgery, oral medicine, and oral pathology, 1989, Volume: 67, Issue:3

    Topics: Administration, Oral; Adult; Dantrolene; Diazepam; Facial Pain; Female; Humans; Injections, Intraven

1989
[The stiff man syndrome].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:11

    Topics: Adult; Diagnosis, Differential; Diazepam; Female; Follow-Up Studies; Humans; Muscle Rigidity; Spasm;

1986
Incidence, significance and remission of tubal spasm during attempted hysteroscopic tubal sterilization.
    The Journal of reproductive medicine, 1985, Volume: 30, Issue:1

    Topics: Diazepam; Fallopian Tube Diseases; Female; Glucagon; Humans; Intraoperative Complications; Meperidin

1985
Drug treatment of spasticity.
    Lancet (London, England), 1970, Oct-31, Volume: 2, Issue:7679

    Topics: Aminobutyrates; Chlordiazepoxide; Diazepam; Humans; Spasm

1970
Letter: Unexplained tetanic spasms.
    Lancet (London, England), 1974, Nov-30, Volume: 2, Issue:7892

    Topics: Adult; Diazepam; Humans; Hysteria; Male; Spasm; Tetanus

1974
Involuntary movements not due to parkinsonism.
    Drug and therapeutics bulletin, 1974, Oct-25, Volume: 12, Issue:22

    Topics: Adrenergic beta-Antagonists; Adult; Athetosis; Child; Chlordiazepoxide; Chorea; Diazepam; Humans; Mo

1974
Epilepsy.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec

1974
Corrales M: Electrically and mechanically induced reflex responses in spasticity and influence of Valium and related drugs.
    Electroencephalography and clinical neurophysiology, 1968, Volume: 25, Issue:4

    Topics: Diazepam; Electric Stimulation; Humans; Muscles; Neural Conduction; Reflex; Spasm

1968
EMG phenomena in the "stiff-man" syndrome.
    Electroencephalography and clinical neurophysiology, 1968, Volume: 25, Issue:4

    Topics: Adult; Aminobutyrates; Diazepam; Electromyography; Female; Humans; Muscles; Procaine; Reflex; Spasm;

1968
[Therapy of spastic syndromes].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Curare; Diazepam; Guaifenesin; Humans;

1969
[Pathogenesis and therapy of tetanus].
    Schweizerische medizinische Wochenschrift, 1970, Aug-29, Volume: 100, Issue:35

    Topics: Diazepam; Heart Arrest; Humans; Hypertension; Muscle Cramp; Neuromuscular Nondepolarizing Agents; Pr

1970
[A case of stiff man syndrome].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, May-08, Volume: 45, Issue:22

    Topics: Aged; Contracture; Diazepam; Electromyography; Glycolysis; Humans; Injections, Intramuscular; Male;

1969
Hemifacial spasm.
    British medical journal, 1972, Dec-16, Volume: 4, Issue:5841

    Topics: Diazepam; Facial Nerve; Facial Paralysis; Humans; Spasm

1972
Complications of myelography with conray meglumin.
    Acta radiologica: diagnosis, 1972, Volume: 13, Issue:0

    Topics: Adult; Aged; Blood Pressure; Depression, Chemical; Diazepam; Female; Headache; Humans; Injections, S

1972
Diazepam as a muscle relaxant.
    The Medical letter on drugs and therapeutics, 1973, Jun-06, Volume: 15, Issue:14

    Topics: Administration, Oral; Diazepam; Humans; Hypnotics and Sedatives; Injections, Intravenous; Muscle Rel

1973
[C34.647-Ba (Lioresal) in the treatment of hypertonic manifestations of multiple sclerosis].
    Bruxelles medical, 1973, Volume: 53, Issue:11

    Topics: Adult; Aged; Aminobutyrates; Chlorobenzenes; Diazepam; Electromyography; Humans; Middle Aged; Multip

1973
Spinal fracture following radiculography using meglumine iothalamate (Conray).
    Neuroradiology, 1973, Volume: 6, Issue:2

    Topics: Adipates; Adult; Contrast Media; Diazepam; Female; Fractures, Bone; Humans; Hypesthesia; Iothalamic

1973
Bilateral renal venous thrombosis. Recovery after peritoneal dialysis.
    Archives of disease in childhood, 1974, Volume: 49, Issue:1

    Topics: Blood Pressure; Diarrhea; Diazepam; Gentamicins; Hematuria; Humans; Infant, Newborn; Infant, Newborn

1974
Experiences in the management of tetanus neonatorum with particular reference to the role of diazepam.
    East African medical journal, 1974, Volume: 51, Issue:1

    Topics: Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Kenya; Male; Spasm; Tetanus; T

1974
Internal anal sphincter derangement with anal fissures.
    Gastroenterology, 1974, Volume: 67, Issue:2

    Topics: Anal Canal; Diazepam; Fissure in Ano; Gastrointestinal Motility; Humans; Manometry; Muscle Contracti

1974
A comparison of baclofen and diazepam in the treatment of spasticity.
    Journal of the neurological sciences, 1974, Volume: 23, Issue:1

    Topics: Adult; Aminobutyrates; Body Weight; Chlorine; Diazepam; Female; Humans; Male; Middle Aged; Multiple

1974
Centrally acting skeletal-muscle relaxants.
    Archives of physical medicine and rehabilitation, 1974, Volume: 55, Issue:8

    Topics: Chemical Phenomena; Chemistry; Chlorzoxazone; Diazepam; Dose-Response Relationship, Drug; Humans; Me

1974
EEG depth leads during stereotaxic brain surgery. A report on 117 cases (5 target points, effects of 13 different drugs).
    Confinia neurologica, 1970, Volume: 32, Issue:2

    Topics: Amides; Amygdala; Antimetabolites; Asparagine; Benzoates; Brain; Brain Diseases; Cerebrovascular Cir

1970
An overdose of Parstelin.
    Anaesthesia, 1971, Volume: 26, Issue:4

    Topics: Adult; Diazepam; Humans; Male; Poisoning; Positive-Pressure Respiration; Spasm; Succinylcholine; Tac

1971
The management of tetanus--a study of 51 cases treated at Muhimbili hospital, Dar es Salaam.
    East African medical journal, 1972, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Male; Middle Age

1972
Treatment of spasmodic torticollis with diazepam.
    Southern medical journal, 1971, Volume: 64, Issue:7

    Topics: Adolescent; Diazepam; Female; Humans; Spasm; Torticollis

1971
Drugs in the management of spasticity.
    Developmental medicine and child neurology, 1971, Volume: 13, Issue:3

    Topics: Aminobutyrates; Barbiturates; Benzene Derivatives; Diazepam; Humans; Mephenesin; Meprobamate; Reflex

1971
Tetanus--the role of diazepam in therapy.
    California medicine, 1971, Volume: 115, Issue:4

    Topics: Diazepam; Humans; Spasm; Tetanus; United States

1971
[The stiff-man syndrome].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1968, Volume: 36, Issue:2

    Topics: Action Potentials; Diazepam; Electromyography; Humans; Male; Middle Aged; Movement Disorders; Muscle

1968
Long-term follow-up on the use of diazepam in the treatment of spasticity.
    American journal of physical medicine, 1968, Volume: 47, Issue:3

    Topics: Diazepam; Humans; Paraplegia; Paresis; Quadriplegia; Rheumatic Diseases; Spasm

1968
[Cause and treatment of spasticity following halothane anesthesia].
    Der Anaesthesist, 1969, Volume: 18, Issue:8

    Topics: Adult; Analgesics; Anesthesia, Inhalation; Benperidol; Body Temperature; Diazepam; Halothane; Humans

1969
Control of the spasms of tetanus with diazepam (Valium). Evaluation of clinical usefulness based upon observations of three childhood cases.
    Clinical pediatrics, 1969, Volume: 8, Issue:12

    Topics: Child; Child, Preschool; Diazepam; Female; Humans; Injections, Intravenous; Male; Spasm; Tetanus

1969
The management of spasticity and rigidity using parenteral diazepam.
    Gerontologia clinica, 1970, Volume: 12, Issue:3

    Topics: Adult; Aged; Ataxia; Central Nervous System Diseases; Diazepam; Fatigue; Female; Humans; Injections,

1970
Diazepam (Valium) in the treatment of tetanus: a report of five cases.
    Southern medical journal, 1970, Volume: 63, Issue:4

    Topics: Aged; Diazepam; Female; Humans; Male; Middle Aged; Muscle Contraction; Myoclonus; Spasm; Tetanus

1970
[Multiple sclerosis. 7. Rehabilitation].
    Lakartidningen, 1970, Jul-15, Volume: 67, Issue:29

    Topics: Ataxia; Diazepam; Exercise Therapy; Humans; Multiple Sclerosis; Self-Help Devices; Spasm; Urination

1970
[Conservative therapy for spasm by traumatic spinal cord injury].
    Kumamoto Igakkai zasshi. The Journal of the Kumamoto Medical Society, 1967, Feb-25, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Animals; Diazepam; Exercise Therapy; Female; Humans; Male; Middle Aged; Phenols;

1967
Measurement of the duration of effect of long-acting diazepam in spastic disorders.
    Archives of physical medicine and rehabilitation, 1968, Volume: 49, Issue:1

    Topics: Adult; Ankle; Delayed-Action Preparations; Diazepam; Electromyography; Humans; Male; Middle Aged; Qu

1968
Clinical experiences on spasticity with a modification of the Mumenthaler pendulum test.
    Paraplegia, 1968, Volume: 6, Issue:2

    Topics: Diazepam; Electric Conductivity; Humans; Knee; Leg; Methods; Movement; Muscles; Spasm; Time Factors

1968
[Treatment of infantile spasms with nitrazepam].
    No to shinkei = Brain and nerve, 1968, Volume: 20, Issue:12

    Topics: Adrenal Cortex Hormones; Anticonvulsants; Child, Preschool; Diazepam; Drug Synergism; Epilepsy; Huma

1968
[Acute poisoning with strychnine-N-oxide hydrochloride (Movellan tablets) and treatment with diazepam].
    Archiv fur Toxikologie, 1969, Volume: 24, Issue:2

    Topics: Adolescent; Antidotes; Chemistry, Clinical; Chromatography, Paper; Diazepam; Diuresis; Female; Human

1969
Use of intravenous diazepam in acute skeletal muscle spasm. Preliminary report.
    Annals of physical medicine, 1964, Volume: Suppl

    Topics: Central Nervous System Diseases; Cervical Vertebrae; Diazepam; Humans; Injections, Intravenous; Inte

1964
Skeletal muscle spasm and some speculations on the mode of action of diazepam.
    Annals of physical medicine, 1964, Volume: Suppl

    Topics: Diazepam; Humans; Motor Neurons; Muscle Contraction; Spasm

1964
Diazepam in the relief of muscle spasm resulting from spinal-cord lesions.
    Annals of physical medicine, 1964, Volume: Suppl

    Topics: Adolescent; Adult; Cerebrovascular Disorders; Cervical Vertebrae; Diazepam; Female; Humans; Male; Mi

1964
Use of diazepam for the relief of spasticity in multiple sclerosis.
    Annals of physical medicine, 1964, Volume: Suppl

    Topics: Diazepam; Humans; Multiple Sclerosis; Muscles; Spasm

1964
[Trials on the treatment of spasticity with Valium].
    Annales medicales de Nancy, 1965, Volume: 4

    Topics: Child; Child, Preschool; Diazepam; Female; Humans; Male; Spasm

1965
Ratio of maximum H reflex to maximum M response as a measure of spasticity.
    Journal of neurology, neurosurgery, and psychiatry, 1966, Volume: 29, Issue:3

    Topics: Diazepam; Electromyography; Humans; Muscles; Reflex; Spasm

1966
The effect of intramuscular diazepam on sustained ankle clonus: a quantitative study.
    Archives of physical medicine and rehabilitation, 1966, Volume: 47, Issue:12

    Topics: Ankle; Central Nervous System Diseases; Diazepam; Electromyography; Humans; Injections, Intramuscula

1966
Evaluation of muscle relaxant drugs by head-drop and by decerebrate rigidity.
    International journal of neuropharmacology, 1966, Volume: 5, Issue:4

    Topics: Animals; Carbamates; Carisoprodol; Cats; Chlordiazepoxide; Diazepam; Electromyography; Gallamine Tri

1966
[A case of stiff-man syndrome in a woman].
    Nederlands tijdschrift voor geneeskunde, 1966, Sep-03, Volume: 110, Issue:36

    Topics: Diabetes Complications; Diazepam; Female; Humans; Middle Aged; Muscular Diseases; Spasm

1966