diazepam has been researched along with Sleep Wake Disorders in 72 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
Excerpt | Relevance | Reference |
---|---|---|
"Diazepam was shown to be significantly more effective than placebo for the abatement of the global anxiety syndrome, as objectively and subjectively rated." | 6.64 | Oral diazepam in hospitaized anxiety patients (with observations on concentration-effect-relationships). ( Dasberg, H, 1975) |
" We studied the clinical importance of this effect in 10 patients, who were receiving long-term treatment with diazepam for anxiety, tension, or difficulty in sleeping, in an eight-week double-blind controlled study during which the diazepam dosage remained constant." | 2.65 | Clinical importance of the interaction of diazepam and cimetidine. ( Abernethy, DR; Greenblatt, DJ; Harmatz, JS; Morse, DS; Shader, RI, 1984) |
" 2 Clobazam dosage ranged from 5 mg daily (paediatric patients) to 120 mg daily (psychiatric in-patients)." | 2.65 | Review of clinical studies on clobazam. ( Koeppen, D, 1979) |
"Diazepam was shown to be significantly more effective than placebo for the abatement of the global anxiety syndrome, as objectively and subjectively rated." | 2.64 | Oral diazepam in hospitaized anxiety patients (with observations on concentration-effect-relationships). ( Dasberg, H, 1975) |
"Those disorders discussed are attention deficit disorder, conduct disorders, anxiety disorders, sleep disorders, schizophrenia, autism, Tourette's syndrome, mental retardation, depressive illness, manic depressive illness, eating disorders, and enuresis." | 2.37 | Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1). ( McDaniel, KD, 1986) |
"Finally, seizure-like nonepileptic disorders were reviewed and differential diagnostic points highlighted." | 2.36 | Seizures and seizure-like states in the child: an approach to emergency management. ( Oppenheimer, EY; Rosman, NP, 1983) |
"The latter 2 cases had been treated as epilepsy." | 1.29 | [Five cases of paroxysmal sleep disturbances]. ( Ikeno, T; Nagai, H, 1993) |
"Night-terrors and somnambulism are comparatively rare in adults and are most often associated with stage 4 sleep, especially delta activity." | 1.27 | Treatment of coexistent night-terrors and somnambulism in adults with imipramine and diazepam. ( Cooper, AJ, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 67 (93.06) | 18.7374 |
1990's | 3 (4.17) | 18.2507 |
2000's | 2 (2.78) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Flynn, S | 1 |
Rossiter, A | 1 |
FREY, U | 1 |
MEUSERT, W | 1 |
VOELLMY, W | 1 |
SPARK, H | 1 |
GOLDMAN, AS | 1 |
Othmer, E | 1 |
Hentschel, HD | 1 |
Sastre y Hernández, M | 1 |
Fichte, K | 1 |
Skolnick, P | 1 |
Paul, SM | 1 |
Allen, RM | 1 |
Werner, V | 1 |
Diehl, LW | 1 |
Ananth, J | 1 |
Van den Steen, N | 1 |
Oppenheimer, EY | 1 |
Rosman, NP | 1 |
Greenblatt, DJ | 2 |
Abernethy, DR | 1 |
Morse, DS | 1 |
Harmatz, JS | 1 |
Shader, RI | 2 |
Winokur, A | 1 |
Rickels, K | 1 |
Kamgar-Parsi, B | 1 |
Wehr, TA | 1 |
Gillin, JC | 1 |
Ehsanullah, RS | 1 |
Galloway, DB | 1 |
Gusterson, FR | 1 |
Kingsbury, AW | 1 |
Holt, RJ | 1 |
Pérez-Cruet, J | 1 |
Kirchner, P | 1 |
Snisarenko, AA | 1 |
Nagai, H | 1 |
Ikeno, T | 1 |
Owens, JA | 1 |
Millman, RP | 1 |
Spirito, A | 1 |
Warner, J | 1 |
Metcalfe, C | 1 |
King, M | 1 |
Viukari, M | 1 |
Linnoila, M | 1 |
Aalto, U | 1 |
Jovanović, UJ | 1 |
Dubnitskaia, EB | 1 |
Basov, AM | 1 |
Doongaji, DR | 1 |
Sheth, A | 1 |
Apte, JS | 1 |
Lakdawala, PD | 1 |
Khare, CB | 1 |
Thatte, SS | 1 |
Koeppen, D | 1 |
Gallagher, RM | 1 |
Keith, PR | 1 |
Anders, TF | 1 |
Skupin, G | 1 |
Franzke, HG | 1 |
Miller, RR | 1 |
Hollister, LE | 1 |
Thompson, WL | 1 |
Harry, TV | 1 |
Johnson, PA | 1 |
Fowler, LK | 2 |
Covington, JS | 1 |
Fassolt, A | 1 |
Zelson, C | 1 |
Dasberg, H | 1 |
Golda, V | 1 |
McDaniel, KD | 1 |
Cooper, AJ | 2 |
Drake, ME | 1 |
Godbout, R | 1 |
Montplaisir, J | 1 |
Rouleau, I | 1 |
Fisher, C | 1 |
Kahn, E | 1 |
Edwards, A | 1 |
Davis, DM | 1 |
Raskin, A | 2 |
Perbellini, D | 1 |
Castellani, A | 1 |
Lescovelli, M | 1 |
Pearlman, CA | 1 |
Greenberg, R | 1 |
Jick, H | 1 |
Hagimori, M | 1 |
Mori, Y | 1 |
Kusumoto, H | 1 |
Aoki, A | 1 |
Tanimoto, H | 1 |
De Buck, R | 1 |
Boon, H | 1 |
Pelc, I | 1 |
Konagaya, K | 1 |
Kawasumi, S | 1 |
Sato, K | 1 |
Takao, K | 1 |
Magnus, RV | 1 |
Rose, M | 1 |
Phanjoo, A | 1 |
Lancaster, NP | 1 |
Pollard, P | 1 |
Knowlson, P | 1 |
Kirven, LE | 1 |
Montero, EF | 1 |
Schulterbrandt, JG | 1 |
Reatig, N | 1 |
Crook, TH | 1 |
Odle, D | 1 |
Padron, C | 1 |
Tansella, M | 1 |
Zimmermann-Tansella, C | 1 |
Lader, M | 1 |
Lingjaerde, O | 1 |
Deberdt, R | 1 |
Bliding, A | 1 |
Sakurai, T | 1 |
Nishizono, M | 1 |
Noiri, T | 1 |
Takeshima, T | 1 |
Yamaguchi, N | 1 |
Okabe, M | 1 |
Ando, J | 1 |
Takeuchi, O | 1 |
Mima, T | 1 |
Okumura, F | 1 |
Onji, H | 1 |
Cremoncini, C | 1 |
Liuzzi, A | 1 |
Glick, BS | 1 |
Schulman, D | 1 |
Turecki, S | 1 |
Collard, J | 1 |
Ose, E | 1 |
Kuschinsky, G | 1 |
Mödlinger, HW | 1 |
6 reviews available for diazepam and Sleep Wake Disorders
Article | Year |
---|---|
The mechanism(s) of action of the benzodiazepines.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Caffeine; Carbolines; C | 1981 |
[The state of psychopharmacotherapy in geriatrics 2].
Topics: Actihaemyl; Aged; Amitriptyline; Bencyclane; Cerebrovascular Circulation; Clorazepate Dipotassium; D | 1980 |
Seizures and seizure-like states in the child: an approach to emergency management.
Topics: Anesthesia, General; Child; Child, Preschool; Diagnosis, Differential; Diazepam; Emergencies; Humans | 1983 |
Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1).
Topics: Adolescent; Aggression; Antidepressive Agents; Antipsychotic Agents; Anxiety, Separation; Attention | 1986 |
Drug therapy. Benzodiazepines (second of two parts).
Topics: Affective Symptoms; Alcoholism; Analgesia; Anesthesia, General; Anesthesia, Obstetrical; Anti-Anxiet | 1974 |
Medical-psychological implications of recent sleep research.
Topics: Adaptation, Psychological; Amphetamine; Barbiturates; Central Nervous System Stimulants; Chloral Hyd | 1970 |
30 trials available for diazepam and Sleep Wake Disorders
Article | Year |
---|---|
[Lormetazepam in the treatment of sleep disorders in a medical practice; double-blind test on 100 patients (author's transl)].
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Double-Blind Method; Female; Humans; Lo | 1981 |
Intramuscular lorazepam. A double-blind comparison with diazepam and placebo.
Topics: Adolescent; Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Double-Blind Method; Femal | 1983 |
Clinical importance of the interaction of diazepam and cimetidine.
Topics: Adult; Anxiety; Cimetidine; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Interactio | 1984 |
Withdrawal responses to abrupt discontinuation of desmethyldiazepam.
Topics: Acute Disease; Adult; Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam; Feeding and | 1984 |
A double-blind crossover study of diazepam rectal suppositories, 5 mg and 10 mg, for sedation in patients with advanced malignant disease.
Topics: Aged; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Aged; Ne | 1982 |
Evaluating the use of benzodiazepines following recent bereavement.
Topics: Aged; Anti-Anxiety Agents; Attitude to Health; Bereavement; Contraindications; Diazepam; Double-Blin | 2001 |
Efficacy and side effects of flurazepam, fosazepam, and nitrazepam as sleeping aids in psychogeriatric patients.
Topics: Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Diazepam; Drug Evaluation; Female; Flurazepam; | 1978 |
[Vigilance pattern and sleep quality under the effect of flunitrazepam].
Topics: Adult; Anti-Anxiety Agents; Attention; Clinical Trials as Topic; Diazepam; Electroencephalography; F | 1978 |
[Use of phenazepam in the treatment of neurotic conditions].
Topics: Adult; Affective Symptoms; Anti-Anxiety Agents; Benzodiazepines; Chemical Phenomena; Chemistry; Clin | 1978 |
Clobazam versus diazepam: a double-blind study in anxiety neurosis [proceedings].
Topics: Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Humans; Motor S | 1979 |
Review of clinical studies on clobazam.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Child; Clinical Trials as Topic; | 1979 |
[Tranxillium 20 (dipotassium chlorazepate) as a 24-hr tranquilizer].
Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Clorazepate Dipotassium; Depression; Diazepam; Headac | 1975 |
Alleviating agitation, apprehension, and related symptoms in geriatric patients: A double-blind comparison of a phenothiazine and a benzodiazepien.
Topics: Aged; Anxiety; Clinical Trials as Topic; Dementia; Depression; Diazepam; Drug Evaluation; Female; Hu | 1975 |
[The clinical efficiency of some hypnotics in cases of preoperative sleeping disturbances (author's transl)].
Topics: Adult; Clinical Trials as Topic; Diazepam; Drug Combinations; Drug Therapy, Combination; Female; Glu | 1975 |
Oral diazepam in hospitaized anxiety patients (with observations on concentration-effect-relationships).
Topics: Administration, Oral; Adult; Anxiety; Diazepam; Dose-Response Relationship, Drug; Female; Hospitaliz | 1975 |
A psychophysiological study of nightmares and night terrors. The suppression of stage 4 night terrors with diazepam.
Topics: Adult; Anxiety; Child; Diazepam; Dreams; Electroencephalography; Evaluation Studies as Topic; Heart | 1973 |
A guide for drug use in depressive disorders.
Topics: Adolescent; Adult; Aged; Anxiety; Chlorpromazine; Clinical Trials as Topic; Depression; Diazepam; Dr | 1974 |
Electroencephalographic study for the evaluation of the effects of 7-chloro-5-phenyl-3H-1,4-benzodiazepine-2-(1H)-one (N-demethyldiazepam) on sleep disturbances in a group of mental patients.
Topics: Adult; Aged; Clinical Trials as Topic; Diazepam; Drug Evaluation; Electroencephalography; Female; Hu | 1974 |
[Clinical evaluation of a new minor tranquilizer Y-6047 for the treatment of sleep disturbance on the night before surgery. II. Comparison with diazepam in a double-blind controlled study].
Topics: Adolescent; Adult; Aged; Azepines; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Middle | 1972 |
[Comparative study of the anxiolytic efficacy of lorazepam (WY 4036) and diazepam (Valium)].
Topics: Adolescent; Adult; Aged; Anxiety; Asthenia; Benzazepines; Clinical Trials as Topic; Diazepam; Evalua | 1972 |
[Comparison of the effects of minor tranquilizers in preoperative sleep disorders by double blind controlled study].
Topics: Azepines; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Nitrazepam; Placebos; Preoperati | 1972 |
Controlled trial of dipotassium clorazepate ("Tranxene") in anxiety.
Topics: Adolescent; Adult; Anxiety; Anxiety Disorders; Benzazepines; Carboxylic Acids; Clinical Trials as To | 1973 |
Comparison of thioridazine and diazepam in the control of nonpsychotic symptoms associated with senility: double-blind study.
Topics: Aged; Behavior; Clinical Trials as Topic; Diazepam; Electrocardiography; Female; Hospitalization; Hu | 1973 |
Depression subtypes and response to phenelzine, diazepam, and a placebo. Results of a nine hospital collaborative study.
Topics: Adolescent; Adult; Anxiety; Bipolar Disorder; Clinical Trials as Topic; Depression; Diazepam; Drug E | 1974 |
[Comparative clinical evaluation of lorazepam (author's transl)].
Topics: Adult; Anxiety Disorders; Benzodiazepinones; Chlorobenzenes; Clinical Trials as Topic; Diazepam; Dru | 1974 |
The residual effects of N-desmethyldiazepam in patients.
Topics: Adolescent; Adult; Amobarbital; Anxiety Disorders; Child; Clinical Trials as Topic; Dealkylation; Di | 1974 |
Effects of different rates of absorption of two benzodiazepins on subjective and objective parameters. Significance for clinical use and risk of abuse.
Topics: Absorption; Anxiety; Diazepam; Female; Hand; Humans; Male; Oxazepam; Placebos; Pulse; Reaction Time; | 1974 |
[Hypnotic effect of Nitrazepam, a new benzodiazepine derivative].
Topics: Bipolar Disorder; Clinical Trials as Topic; Diazepam; Humans; Hypnotics and Sedatives; Neurotic Diso | 1967 |
[Animal and clinical experiments on the hypnotic effects of nitrazepam].
Topics: Adult; Aged; Animals; Cats; Cerebral Cortex; Clinical Trials as Topic; Diazepam; Electric Stimulatio | 1968 |
[Studies on preoperative anxiety and sleep disorders].
Topics: Anxiety; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Pentobarbital; Placebos; Preopera | 1968 |
36 other studies available for diazepam and Sleep Wake Disorders
Article | Year |
---|---|
Chemical addiction: Daniella's decisions.
Topics: Adult; Analgesics; Decision Making; Diazepam; Drug Tolerance; Female; Humans; Medical Staff, Hospita | 2003 |
[Possibilities of use of a new benzodiazepin derivatives, Valium Roche in internal medicine].
Topics: Anticonvulsants; Antidepressive Agents; Diazepam; Humans; Hypnotics and Sedatives; Internal Medicine | 1963 |
[EXPERIENCES WITH A NEW PSYCHOTROPIC PREPARATION OF THE LIBRIUM GROUP (RO 5-2807 VALIUM)].
Topics: Chlordiazepoxide; Depression; Diazepam; Humans; Neurotic Disorders; Psychotic Disorders; Psychotropi | 1963 |
[TREATMENT OF SLEEP DISORDERS IN HOSPITALIZED AND AMBULANT PATIENTS WITH VALIUM].
Topics: Diazepam; Humans; Sleep Wake Disorders; Tranquilizing Agents | 1964 |
DIAZEPAM INTOXICATION IN A CHILD.
Topics: Ataxia; Child; Chlordiazepoxide; Diazepam; Electroencephalography; Metabolism; Poisoning; Sleep Wake | 1965 |
[Pathophysiology of the disturbed sleep and its susceptibility to psychopharmaca].
Topics: Diazepam; Electroencephalography; Electromyography; Humans; Male; Movement; Personality; Personality | 1966 |
Attenuation of drug-induced anxiety dreams and pavor nocturnus by benzodiazepines.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Anxiety; Cloraze | 1983 |
Successful treatment of human non-24-hour sleep-wake syndrome.
Topics: Adult; Diazepam; Flurazepam; Humans; Male; Periodicity; Sleep Wake Disorders; Thyroxine; Vitamin B 1 | 1983 |
Hypersomnic diazepam abstinence syndrome: a case report.
Topics: Adult; Antisocial Personality Disorder; Cyclothymic Disorder; Diazepam; Disorders of Excessive Somno | 1982 |
[Tasks and problems of general medical care in certain groups of disorders. Patients with mixed (motor and sensory) paralyses--from a neurological viewpoint].
Topics: Baclofen; Demyelinating Diseases; Diazepam; Electrogalvanism, Intraoral; Exercise Therapy; Hemiplegi | 1982 |
[Effect of the beta-adrenoblocker propranolol and the tranquilizer seduxen on natural sleep in cats].
Topics: Animals; Cats; Diazepam; Drug Interactions; Humans; Male; Propranolol; Sleep; Sleep Stages; Sleep Wa | 1981 |
[Five cases of paroxysmal sleep disturbances].
Topics: Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencephalography; E | 1993 |
Sleep terrors in a 5-year-old girl.
Topics: Child, Preschool; Diazepam; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Sleep W | 1999 |
The impact of benzodiazepines on clinical practice--considerations for therapeutic use.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Diazepam; Female; Humans; Male; Mental Disorders; Sleep Wake Di | 1979 |
Night terrors. A review of the psychology, neurophysiology, and therapy.
Topics: Adolescent; Anxiety; Child; Child, Preschool; Diazepam; Electroencephalography; Humans; Imipramine; | 1975 |
What we know about sleep disorders in children.
Topics: Adolescent; Child; Child, Preschool; Diazepam; Dreams; Enuresis; Female; Humans; Imipramine; Male; S | 1976 |
A guide to the use of hypnotic drugs.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Drug Interactions; Flurazepam; | 1979 |
Valium: a discussion of current issues.
Topics: Age Factors; Ambulatory Care; Anxiety; Automobile Driving; Diazepam; Drug Interactions; Drug Labelin | 1977 |
Management of alcohol withdrawal syndromes.
Topics: Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relationship, Dru | 1978 |
The effectiveness of temazepam as a hypnotic: an open, multi-centre assessment in 804 patients with sleep disorders.
Topics: Aged; Diazepam; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Sleep Wake Disorders; Su | 1978 |
Temazepam (Euhypnos) as a hypnotic: a twelve-week trial in general practice.
Topics: Adult; Aged; Diazepam; Family Practice; Female; Headache; Humans; Hypnotics and Sedatives; Male; Mid | 1977 |
Temazepam (Euhypnos) as a hypnotic: a multicentre trial in general practice.
Topics: Adolescent; Adult; Aged; Diazepam; Drug Evaluation; Family Practice; Female; Humans; Hypnotics and S | 1977 |
Acute management of neonatal addiction.
Topics: Antidiarrheals; Chlorpromazine; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant | 1975 |
Diazepam alleviates phase advance of circadian rhythm of activity in the genetically hypertensive non-obese rats of Koletsky type.
Topics: Animals; Behavior, Animal; Circadian Rhythm; Depression; Diazepam; Hypertension; Rats; Rats, Inbred | 1991 |
Treatment of coexistent night-terrors and somnambulism in adults with imipramine and diazepam.
Topics: Adult; Diazepam; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Middle Aged; Sleep Wak | 1987 |
A case of parasomnia at REM sleep onset.
Topics: Adult; Anticonvulsants; Diagnosis, Differential; Diazepam; Dreams; Epilepsy; Humans; Male; Sleep Sta | 1987 |
Hypnogenic paroxysmal dystonia: epilepsy or sleep disorder? A case report.
Topics: Adult; Carbamazepine; Diazepam; Dystonia; Epilepsy; Humans; Male; Sleep; Sleep Wake Disorders; Syndr | 1985 |
Smoking and clinical drug effects.
Topics: Age Factors; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Female; Humans; Male; M | 1974 |
[A new, particular syndrome induced by large doses of diazepam?].
Topics: Adult; Aged; Cardiovascular Diseases; Depression; Diazepam; Dose-Response Relationship, Drug; Humans | 1973 |
Lorazepam in the treatment of severe anxiety and anxiety associated with psychotic conditions.
Topics: Adult; Aggression; Amitriptyline; Anxiety Disorders; Ataxia; Benzodiazepinones; Bipolar Disorder; Ch | 1973 |
[Tybamate, recently synthetized anxiolytic agent, in the treatment of emotional and neurovegetative symptoms of hyperthyroidism. Clinico-statistical study].
Topics: Adolescent; Adult; Affective Symptoms; Aged; Animals; Anxiety; Autonomic Nervous System; Carbamates; | 1972 |
Diazepam (Valium) treatment in childhood sleep disorders. A preliminary investigation.
Topics: Child; Diazepam; Enuresis; Female; Humans; Imipramine; Male; Sleep Wake Disorders; Somnambulism; Thi | 1971 |
Initial psychopharmacological study of lorazepam (Wy 4036).
Topics: Adult; Anxiety; Anxiety Disorders; Benzazepines; Chlordiazepoxide; Diazepam; Female; Humans; Male; O | 1971 |
[Benzodiazepines and addictive hypnotics as adjuvants in the treatment of depression with amitriptyline].
Topics: Amitriptyline; Chlordiazepoxide; Depression; Diazepam; Drug Synergism; Humans; Neurotic Disorders; S | 1971 |
[Continuous sleep disorders].
Topics: Chlordiazepoxide; Delayed-Action Preparations; Diazepam; Hexobarbital; Humans; Hypnotics and Sedativ | 1970 |
[Experience with a new kind of sleep inducing substance].
Topics: Chlordiazepoxide; Diazepam; Humans; Hypnotics and Sedatives; Sleep Wake Disorders | 1967 |