Page last updated: 2024-10-25

diazepam and Schizophrenia

diazepam has been researched along with Schizophrenia in 145 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"The lorazepam-diazepam protocol can rapidly relieve retarded catatonia in schizophrenia."9.17Lorazepam-diazepam protocol for catatonia in schizophrenia: a 21-case analysis. ( Huang, TL; Lin, CC, 2013)
"Efficacy data support the use of diazepam in treating prodromal and early warning signs of symptom exacerbation in schizophrenia."9.09Diazepam treatment of early signs of exacerbation in schizophrenia. ( Breier, AF; Buchanan, RW; Carpenter, WT; Kirkpatrick, B, 1999)
"The purpose of the present paper was to remind physicians that hypothermia is a possible side-effect of combining zotepine, valproate,and benzodiazepine."7.72Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy. ( Chen, KC; Chen, PS; Yang, MJ; Yang, YK; Yeh, TL, 2003)
"Previously, it was shown that subchronic application of the NMDA receptor antagonist ketamine (Ket) induces schizophrenia-related alterations, e."7.72Ketamine-induced changes in rat behaviour: a possible animal model of schizophrenia. Test of predictive validity. ( Becker, A; Grecksch, G, 2004)
"Trials of novel compounds for the treatment of schizophrenia are typically tested in patients following brief withdrawal of ongoing medication despite known long-term changes in the dopamine (DA) system following chronic antipsychotic drug therapy."5.40Prior antipsychotic drug treatment prevents response to novel antipsychotic agent in the methylazoxymethanol acetate model of schizophrenia. ( Cook, JM; Gill, KM; Grace, AA; Poe, MM, 2014)
"Schizophrenia is believed to arise from an interaction of genetic predisposition and adverse environmental factors, with stress being a primary variable."5.39Peripubertal diazepam administration prevents the emergence of dopamine system hyperresponsivity in the MAM developmental disruption model of schizophrenia. ( Du, Y; Grace, AA, 2013)
"We describe a case of neuroleptic malignant syndrome (NMS) associated with the use of ziprasidone."5.34Neuroleptic malignant syndrome induced by ziprasidone on the second day of treatment. ( Cansel, N; Herken, H; Ozen, ME; Savas, HA; Yumru, M, 2007)
"The lorazepam-diazepam protocol can rapidly relieve retarded catatonia in schizophrenia."5.17Lorazepam-diazepam protocol for catatonia in schizophrenia: a 21-case analysis. ( Huang, TL; Lin, CC, 2013)
"Efficacy data support the use of diazepam in treating prodromal and early warning signs of symptom exacerbation in schizophrenia."5.09Diazepam treatment of early signs of exacerbation in schizophrenia. ( Breier, AF; Buchanan, RW; Carpenter, WT; Kirkpatrick, B, 1999)
"We have shown previously that aberrant hippocampal (HPC) output underlies the dopamine (DA) dysfunction observed in the methylazoxymethanol acetate (MAM) developmental model of schizophrenia in the rodent."3.77A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia. ( Aras, S; Cook, JM; Gill, KM; Grace, AA; Lodge, DJ, 2011)
"The purpose of the present paper was to remind physicians that hypothermia is a possible side-effect of combining zotepine, valproate,and benzodiazepine."3.72Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy. ( Chen, KC; Chen, PS; Yang, MJ; Yang, YK; Yeh, TL, 2003)
"Previously, it was shown that subchronic application of the NMDA receptor antagonist ketamine (Ket) induces schizophrenia-related alterations, e."3.72Ketamine-induced changes in rat behaviour: a possible animal model of schizophrenia. Test of predictive validity. ( Becker, A; Grecksch, G, 2004)
" In 37 patients with anxiety depression the DST was combined with the diazepam test."3.67[Use of the dexamethasone test in the differential diagnosis of depressive states]. ( Gordon, OI; Nuller, IuL; Ostroumova, MN, 1986)
"Three patients, aged 23-33 years, with the diagnosis of schizophrenia, developed symptoms of tardive dyskinesia while receiving neuroleptic treatment, mostly with haloperidol."3.65Diazepam in the treatment of tardive dyskinesia. Preliminary observations. ( Singh, MM, 1976)
"Diazepam was given intravenously to the patients at a rate of 5 mg per 30 seconds."2.70Immediate effect of intravenous diazepam in neuroleptic-induced acute akathisia: an open-label study. ( Ashby, CR; Hirose, S, 2002)
"Diazepam treatment led to a return of the patient's usual condition in seven of 11 episodes."2.66Diazepam treatment of early symptoms of schizophrenic relapse. ( Buchanan, RW; Carpenter, WT; Jauch, D; Kirkpatrick, B; Waltrip, RW, 1989)
" By measuring the brain function using computer period analysis of cerebral biopotentials, dose-efficacy relations were found (in the range of 25-75 mcg) which suggest the bioavailability of LHM at the CNS level."2.64Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram. ( Akpinar, S; Herrmann, WM; Itil, TM, 1975)
"Trials of novel compounds for the treatment of schizophrenia are typically tested in patients following brief withdrawal of ongoing medication despite known long-term changes in the dopamine (DA) system following chronic antipsychotic drug therapy."1.40Prior antipsychotic drug treatment prevents response to novel antipsychotic agent in the methylazoxymethanol acetate model of schizophrenia. ( Cook, JM; Gill, KM; Grace, AA; Poe, MM, 2014)
"Schizophrenia is believed to arise from an interaction of genetic predisposition and adverse environmental factors, with stress being a primary variable."1.39Peripubertal diazepam administration prevents the emergence of dopamine system hyperresponsivity in the MAM developmental disruption model of schizophrenia. ( Du, Y; Grace, AA, 2013)
" There were no other adverse events."1.36The safety and efficacy of benzodiazepine-modified treatments as a special form of unmodified ECT. ( Andrade, C; Bhakta, S; Bhirud, M; Fernandes, P; Mahadeshwar, S; Shah, N, 2010)
"We describe a case of neuroleptic malignant syndrome (NMS) associated with the use of ziprasidone."1.34Neuroleptic malignant syndrome induced by ziprasidone on the second day of treatment. ( Cansel, N; Herken, H; Ozen, ME; Savas, HA; Yumru, M, 2007)
" It highlights three features: first, MHN can safely prescribe psychiatric medication in combination with concordance therapy."1.33Pharmacological management of akathisia in combination with psychological interventions by a mental health nurse consultant. ( Arya, P; Bennett, J; Gray, R; Jones, M; Lucas, B, 2006)
"The diazepam dose was adjusted daily to avoid oversedation."1.27High doses of diazepam improve neuroleptic-resistant chronic schizophrenic patients. ( Bloom, D; Nair, NP; Nestoros, JN; Pulman, JR; Schwartz, G, 1983)
"Diazepam treatment with doses up to 250 mg/day caused no significant rise in SPL, while the treatment with doses of higher than 250 mg/day resulted in a mild but still significant increase in SPL."1.27High dose diazepam treatment and its effect on prolactin secretion in adolescent schizophrenic patients. ( Ben David, M; Tyano, S; Weizman, A; Wijsenbeek, H, 1984)
" We also report results on using this assay in a pharmacokinetic study of high doses of diazepam used to treat chronic schizophrenic patients."1.27Liquid-chromatographic assay of diazepam and its major metabolites in serum, and application to pharmacokinetic study of high doses of diazepam in schizophrenics. ( Moroji, T; Motomura, H; Noguchi, T; Sekiguchi, R; Tada, K, 1985)
"Diazepam was also effective in reducing the cardiac response."1.26Changes in heart rate during administration of local anesthetics in neuropsychiatric patients. ( Nakajima, T; Yakata, H; Yokobayashi, T, 1979)

Research

Studies (145)

TimeframeStudies, this research(%)All Research%
pre-1990106 (73.10)18.7374
1990's15 (10.34)18.2507
2000's12 (8.28)29.6817
2010's12 (8.28)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tan, T1
Wang, W1
Williams, J1
Ma, K1
Cao, Q1
Yan, Z1
Afonso, P1
Saraiva, S1
Gameiro, Z1
Du, Y3
Grace, AA5
Lin, CC1
Huang, TL1
Gill, KM2
Cook, JM2
Poe, MM1
Mukhopadhaya, K1
Krishnaiah, R1
Taye, T1
Nigam, A1
Bailey, AJ1
Sivakumaran, T1
Fineberg, NA1
Shah, N1
Mahadeshwar, S1
Bhakta, S1
Bhirud, M1
Fernandes, P1
Andrade, C1
Morera-Fumero, AL1
Abreu-Gonzalez, P1
Feifel, D1
Shilling, PD1
Melendez, G1
Loga-Zec, S1
Loga, S1
Lodge, DJ1
Aras, S1
Bellgrove, MA1
Vance, A1
Bradshaw, JL1
Chen, KC1
Yang, YK1
Chen, PS1
Yeh, TL1
Yang, MJ1
FELDMAN, PE1
POELDINGER, W1
GROSS, H1
KALTENBAECK, E1
HOLLISTER, LE3
BENNETT, JL1
KIMBELL, I2
SAVAGE, C1
OVERALL, JE4
KALINA, RK1
MACULANS, GA1
LEHMANN, HE2
BAN, TA2
INVERNIZZI, G1
DEBERDT, R2
HARDER, A1
GOLD, RL1
DRIBBEN, IS1
DEAN, SR1
GALAMBOS, M1
Sielk, M1
Bowers, L1
Callaghan, P1
Clark, N1
Evers, C1
Becker, A1
Grecksch, G1
Yee, BK1
Keist, R1
von Boehmer, L1
Studer, R1
Benke, D1
Hagenbuch, N1
Dong, Y1
Malenka, RC1
Fritschy, JM1
Bluethmann, H1
Feldon, J1
Möhler, H1
Rudolph, U1
Jones, M1
Bennett, J1
Gray, R1
Arya, P1
Lucas, B1
Hashimoto, T1
Lewis, DA1
Ozen, ME1
Yumru, M1
Savas, HA1
Cansel, N1
Herken, H1
McLeod, MC1
Sundram, S1
Dean, B1
Belmaker, RH3
Lerner, Y2
Ebstein, RP1
Kim, JS1
Kornhuber, HH1
Schmid-Burgk, W1
Holzmüller, B1
Singh, MM2
Becker, RE1
Pitman, RK1
Nasrallah, HA1
Lal, H1
Dufresne, RL1
Weber, SS1
McCalley-Whitters, M1
Nuller, JL1
Tochilov, VA1
Shirokov, VD1
Nishikawa, T1
Tsuda, A1
Tanaka, M1
Koga, I1
Uchida, Y1
Rhoades, HM1
Nestoros, JN2
Nair, NP2
Pulman, JR1
Schwartz, G1
Bloom, D1
Gramsch, C1
Emrich, HM3
John, S1
Haas, S3
Beckmann, H3
Zaudig, M1
von Zerssen, D2
Rommelspacher, H1
Barbey, M1
Strauss, S1
Greiner, B1
Fähndrich, E1
Altmann, H1
Dose, M1
Weizman, A2
Tyano, S2
Wijsenbeek, H2
Ben David, M1
Kaminer, Y1
Munitz, H2
Jimerson, DC1
van Kammen, DP1
Post, RM1
Docherty, JP1
Bunney, WE1
Boleloutskiĭ, Z1
Arató, M1
Bagdy, G1
Zuardi, AW1
Morais, SL1
Guimarães, FS1
Mechoulam, R1
Benazzi, F1
Mazzoli, M1
Rossi, E1
Jaspert, A1
Ebert, D1
Rosebush, PI1
Mazurek, MF1
Remington, G2
Fornazzari, L1
Sethna, R1
Vieweg, WV1
Bustillo, J1
Buchanan, RW3
Carpenter, WT3
Schröder, J2
Bubeck, B1
Demisch, S1
Sauer, H1
Miyaoka, H1
Shishikura, K1
Otsubo, T1
Muramatsu, D1
Kamijima, K1
Kirkpatrick, B2
Breier, AF1
Hoffmann-Richter, U1
Hatta, K1
Takahashi, T1
Nakamura, H1
Yamashiro, H1
Endo, H1
Kito, K1
Fujii, S1
Matsuzaki, I1
Masui, K1
Yonezawa, Y1
Chong, SA1
Tan, CH1
Hirose, S1
Ashby, CR1
Yakata, H1
Yokobayashi, T1
Nakajima, T1
Trabucchi, M1
Ba, G1
Nistri, A1
Bjerkenstedt, L2
Gullberg, B1
Härnryd, C1
Sedvall, G1
Holzman, PS1
Baumann, P1
Azcarate, CL1
Weizman, R1
David, MB1
Lwow, E1
Levitin, A1
Saito, M1
Ruskin, P1
Averbukh, I1
Dasberg, H1
Kryzhanovskiĭ, GN1
Aliev, MN1
Adebimpe, VR1
McLeod, MN1
Fisher, P1
Abrams, RS1
Bellak, L2
Itil, TM1
Herrmann, WM1
Akpinar, S1
Velamoor, VR1
Sczesni, B1
Becker, H1
Bittkau, S1
von Baumgarten, F1
Truong, DD1
Przuntek, H1
Bacher, NM1
Field, PB1
Elkashef, A1
Waltrip, RW1
Jauch, D1
Suranyi-Cadotte, BE1
Lal, S1
Gauthier, S1
Smulevich, AB2
Vorob'ev, VIu2
Dubnitskaia, EB1
Maksimov, VI1
Novikov, VN1
Tarasova, TP1
Abrosimov, AI1
Hermesh, H1
Molcho, A1
Schnetzler, JP1
Préaubert, G1
Schnetzler, F1
Csernansky, JG1
Riney, SJ1
Lombrozo, L1
Nuller, IuL1
Ostroumova, MN1
Gordon, OI1
Roberts, K1
Vass, N1
Finkel, JA1
Tada, K1
Moroji, T1
Sekiguchi, R1
Motomura, H1
Noguchi, T1
Keegan, DL1
Rajput, AH1
Dencker, SJ1
Frankenberg, K1
Malm, U1
Zell, B1
Máthé, V1
Kassay, G1
Tüske, M1
Whitlock, FA1
Price, J1
Udabe, RU1
Newbold, HL1
Mosher, LR1
Aleksandrovskiĭ, IuA3
Bragina, NN1
Fleĭs, EP1
Seeman, MV1
Denber, HC1
Goldner, F1
Prokudin, VN3
Chassan, JB1
Gediman, HK1
Hurvich, M1
Raskin, A2
Schulterbrandt, JG1
Reatig, N1
Crook, TH1
Odle, D1
Ayd, FJ1
Rickels, K1
Weise, CC1
Clark, EL1
Jenkins, BW1
Rose, CK1
Rosenfeld, H1
Gordon, PE1
Zsadányi, O1
Molnár, C1
Karno, M1
Gram, LF1
Overo, K1
Kirk, L1
Gundlach, R1
Engelhardt, DM1
Hankoff, L1
Paley, H1
Rudorfer, L1
Bird, E1
Michaux, L1
Gallot, HM1
Schneider, JJ1
Sakurai, T1
Nishizono, M1
Noiri, T1
Kammerer, M1
Wartel, R1
Gurfein, L1
Weil, J1
Wysoki, V1
Gelb, F1
Angst, J1
Takeshima, T1
Yamaguchi, N1
Okabe, M1
Ando, J1
Takeuchi, O1
Soyka, D1
Fracchia, J1
Sheppard, C1
Merlis, S1
Korczyn, AD1
Goldberg, GJ1
Glatzel, J1
Borelli, N1
Marjerrison, G1
Naviau, J1
Wolpowitz, B1
Roux, JT1
Dally, P1
Perlson, P1
Tobin, JM1
Vikhliaev, IuI1
Klygul', TA1
Adronati, SA1
Langner, E1
Spiegelberg, U1
Petrilowitsch, N1
Betz, B1
Irvine, BM1
Baliarda, A1
Shelton, J1
Hodel, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
MK-0777 for the Treatment of Cognitive Impairments in Patients With Schizophrenia[NCT00505076]Phase 263 participants (Actual)Interventional2007-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Composite MATRICS Consensus Cognitive Battery Score

The primary outcome measure is the composite score on the Matrics Consensus Cognitive Battery (MCCB). The MCCB composite score is a standardized mean of the seven domain scores. T-scores are standardized to normative data, and have an estimated mean of 50 and SD of 10 in the general healthy population. Data reduction for analysis of neurocognitive testing used the following steps: i) individual neurocognitive test scores at baseline and follow-up were converted to t-scores; ii) t-scores within the pre-specified cognitive domains measured by more than one test were averaged to obtain a domain-specific t-score; and iii) domain-specific t-scores were averaged to create the MCCB composite score. (NCT00505076)
Timeframe: 4 weeks

Interventioncomposite score (Mean)
MK-077 8 mg BID27.9
MK-0777 3 mg BID31.3
Placebo BID32.5

Schizophrenia Cognition Rating Scale (SCoRS) Score

The Schizophrenia Cognition Rating Scale (SCoRS) assessed functional capacity. The SCoRS Interviewer Global Rating of function has a range 1 to 10. Higher ratings indicate greater impairment. (NCT00505076)
Timeframe: 4 Weeks (Baseline to End of Treatment)

,,
InterventionSCoRS Score (Mean)
BaselineEnd of Treatment
MK-077 8 mg BID4.14.0
MK-0777 3 mg BID4.84.6
Placebo BID3.83.6

UPSA(UCSD Performance-Based Skills Assessment) Summary Score

The UCSD Performance-Based Skills Assessment assessed functional capacity. The UPSA Summary Score has a range from 0 to 120. A higher score indicates less impairment. (NCT00505076)
Timeframe: Baseline and end of treatment, a total of four weeks.

,,
InterventionUPSA Summary Score (Mean)
BaselineEnd of Treatment
MK-077 8 mg BID91.790.4
MK-0777 3 mg BID85.086.3
Placebo BID95.096.5

Reviews

10 reviews available for diazepam and Schizophrenia

ArticleYear
[Problems with the treatment of schizophrenics in the doctor's office].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Acute Disease; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Drug Therapy, Combination

2003
Prodromal symptoms vs. early warning signs and clinical action in schizophrenia.
    Schizophrenia bulletin, 1995, Volume: 21, Issue:4

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Humans; Psychiatric Status Rating Scales; Recur

1995
[ECT: The apple of discord in modern psychiatry (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1979, Jan-03, Volume: 68, Issue:1

    Topics: Aggression; Anxiety; Atropine; Biogenic Amines; Confusion; Cyclic AMP; Depression; Diazepam; Electro

1979
Minor tranquilizers in the treatment of aggression.
    The Journal of nervous and mental disease, 1975, Volume: 160, Issue:2-1

    Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Depression; Diazepam; Epilepsy;

1975
[A valproic acid-diazepam combination as an alternative to neuroleptic treatment].
    Annales medico-psychologiques, 1988, Volume: 146, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Diazepam; Drug Combinations; Female; Humans; Male;

1988
Use of beta-adrenergic receptor blocking drugs in psychiatry.
    Drugs, 1974, Volume: 8, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Anxiety; Chlordiazepoxide; Di

1974
Clinical experience with a new psychotropic drug, trazodone: a review of literature.
    Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:10

    Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depressio

1973
[Features of the clinical effect of benzodiazepine derivatives (according to the findings of comparative studies). Review of the literature].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:2

    Topics: Adjustment Disorders; Aggression; Animals; Antisocial Personality Disorder; Barbiturates; Benzazepin

1973
Side effects of depot fluphenazines.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Agranulocytosis; Barbiturates; Basal Ganglia Diseases; Benztropine; Biperiden; Delayed-Action Prepar

1974
[Recent developments in psychopharmacology].
    Praxis, 1968, Feb-06, Volume: 57, Issue:5

    Topics: Antidepressive Agents; Barbiturates; Bipolar Disorder; Chlormethiazole; Depression; Diazepam; Electr

1968

Trials

30 trials available for diazepam and Schizophrenia

ArticleYear
Lorazepam-diazepam protocol for catatonia in schizophrenia: a 21-case analysis.
    Comprehensive psychiatry, 2013, Volume: 54, Issue:8

    Topics: Anti-Anxiety Agents; Catatonia; Clinical Protocols; Diazepam; Drug Therapy, Combination; Humans; Lor

2013
Prophylactic effect of neuroleptics in symptom-free schizophrenics.
    Psychopharmacology, 1982, Volume: 77, Issue:4

    Topics: Adult; Antipsychotic Agents; Chlorpromazine; Diazepam; Female; Haloperidol; Humans; Imipramine; Male

1982
The significance of treatment effects across several independent studies.
    Journal of psychiatric research, 1981, Volume: 16, Issue:4

    Topics: Antipsychotic Agents; Anxiety Disorders; Arousal; Clinical Trials as Topic; Diazepam; Dihydroergotox

1981
Therapeutic effects of GABA-ergic drugs in affective disorders. A preliminary report.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Analgesics; Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as

1983
Diazepam in schizophrenia: a preliminary double-blind trial.
    The American journal of psychiatry, 1982, Volume: 139, Issue:4

    Topics: Adult; Clinical Trials as Topic; Diazepam; Dose-Response Relationship, Drug; Double-Blind Method; Fe

1982
Analgesic and euphoric effects of high dose diazepam in schizophrenia.
    Neuropsychobiology, 1982, Volume: 8, Issue:3

    Topics: Adult; Analgesia; Diazepam; Endorphins; Euphoria; Female; Humans; Male; Middle Aged; Naloxone; Pain;

1982
Placebo response in refractory tardive akathisia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1993, Volume: 38, Issue:4

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Diazepam; Double-Blind Method; Humans; Male; Middle A

1993
Prodromal symptoms vs. early warning signs and clinical action in schizophrenia.
    Schizophrenia bulletin, 1995, Volume: 21, Issue:4

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Humans; Psychiatric Status Rating Scales; Recur

1995
Diazepam treatment of early signs of exacerbation in schizophrenia.
    The American journal of psychiatry, 1999, Volume: 156, Issue:2

    Topics: Acute Disease; Adult; Age of Onset; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Drug Admini

1999
The predictive value of benzodiazepine tolerance in persistently aggressive schizophrenia.
    Neuropsychobiology, 1999, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Aggression; Biomarkers; Diazepam; Drug Tolerance; Humans; Hypnotics and Sedatives

1999
Immediate effect of intravenous diazepam in neuroleptic-induced acute akathisia: an open-label study.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:6

    Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Anti-Anxiety Agents; Antipsychotic Agents; Bipolar Di

2002
Acute high-dose parenteral haloperidol treatment of psychosis.
    The American journal of psychiatry, 1979, Volume: 136, Issue:8

    Topics: Acute Disease; Adult; Bipolar Disorder; Blood Pressure; Clinical Trials as Topic; Diazepam; Dose-Res

1979
Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adolescent; Adult; Aged; Biological Availability; Child; Child, Preschool; Clinical Trials as Topic;

1975
Melperone in the treatment of schizophrenia.
    Acta psychiatrica Scandinavica. Supplementum, 1989, Volume: 352

    Topics: Antipsychotic Agents; Butyrophenones; Diazepam; Double-Blind Method; Drug Therapy, Combination; Homo

1989
Diazepam treatment of early symptoms of schizophrenic relapse.
    The Journal of nervous and mental disease, 1989, Volume: 177, Issue:1

    Topics: Administration, Oral; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Recurrence; Schizoph

1989
Double-blind comparison of alprazolam, diazepam, and placebo for the treatment of negative schizophrenic symptoms.
    Archives of general psychiatry, 1988, Volume: 45, Issue:7

    Topics: Adult; Alprazolam; Ambulatory Care; Clinical Trials as Topic; Diazepam; Double-Blind Method; Humans;

1988
A controlled one-year study of pipotiazine palmitate and fluphenazine decanoate in chronic schizophrenic syndromes. Evaluation of results at 6 and 12 months' trial.
    Acta psychiatrica Scandinavica. Supplementum, 1973, Volume: 241

    Topics: Adult; Aged; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Clinical Trials as

1973
Clinical experience with a new psychotropic drug, trazodone: a review of literature.
    Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:10

    Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depressio

1973
Studies with new drugs in the treatment of convulsive disorders.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1968, Volume: 1, Issue:3

    Topics: Adult; Aggression; Anticonvulsants; Anxiety; Carbamazepine; Clinical Trials as Topic; Diazepam; Dibe

1968
Ego function assessment of analytic psychotherapy combined with drug therapy.
    The Journal of nervous and mental disease, 1973, Volume: 157, Issue:6

    Topics: Adult; Clinical Trials as Topic; Defense Mechanisms; Diazepam; Ego; Evaluation Studies as Topic; Fem

1973
Depression subtypes and response to phenelzine, diazepam, and a placebo. Results of a nine hospital collaborative study.
    Archives of general psychiatry, 1974, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Anxiety; Bipolar Disorder; Clinical Trials as Topic; Depression; Diazepam; Drug E

1974
Thiothixene and thioridazine in anxiety.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 125, Issue:0

    Topics: Antisocial Personality Disorder; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Fema

1974
A double-blind outpatient study of diazepam (Valium) and placebo.
    Psychopharmacologia, 1966, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Ambulatory Care; Anxiety; Clinical Trials as Topic; Depressive Disorder, Major; D

1966
[Hypnotic effect of Nitrazepam, a new benzodiazepine derivative].
    No to shinkei = Brain and nerve, 1967, Volume: 19, Issue:11

    Topics: Bipolar Disorder; Clinical Trials as Topic; Diazepam; Humans; Hypnotics and Sedatives; Neurotic Diso

1967
[Clinical experimentation with desipramine with statistical control].
    Annales medico-psychologiques, 1968, Volume: 1, Issue:1

    Topics: Adult; Aged; Anorexia Nervosa; Barbiturates; Bipolar Disorder; Chlordiazepoxide; Chlorpromazine; Cli

1968
[Animal and clinical experiments on the hypnotic effects of nitrazepam].
    No to shinkei = Brain and nerve, 1968, Volume: 20, Issue:3

    Topics: Adult; Aged; Animals; Cats; Cerebral Cortex; Clinical Trials as Topic; Diazepam; Electric Stimulatio

1968
[The effect of psychopharmacological drugs and other central nervous system effecting drugs on experimental nystagmus].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1968, Volume: 36, Issue:9

    Topics: Amitriptyline; Apomorphine; Aporphines; Barbiturates; Chlordiazepoxide; Chlorpromazine; Clinical Tri

1968
Combination medications in psychiatric treatment: patterns in a group of elderly hospital patients.
    Journal of the American Geriatrics Society, 1971, Volume: 19, Issue:4

    Topics: Age Factors; Aged; Amitriptyline; Antidepressive Agents; Antihypertensive Agents; Antisocial Persona

1971
Triavil and Etrafon.
    The Medical letter on drugs and therapeutics, 1966, Feb-25, Volume: 8, Issue:4

    Topics: Amitriptyline; Chlordiazepoxide; Clinical Trials as Topic; Depression; Diazepam; Female; Humans; Mep

1966
Diazepam in long-term chronic schizophrenia.
    The American journal of psychiatry, 1966, Volume: 122, Issue:11

    Topics: Clinical Trials as Topic; Diazepam; Female; Humans; Middle Aged; Placebos; Schizophrenia

1966

Other Studies

107 other studies available for diazepam and Schizophrenia

ArticleYear
Stress Exposure in Dopamine D4 Receptor Knockout Mice Induces Schizophrenia-Like Behaviors via Disruption of GABAergic Transmission.
    Schizophrenia bulletin, 2019, 09-11, Volume: 45, Issue:5

    Topics: Animals; Behavior, Animal; Cognitive Dysfunction; Diazepam; Exploratory Behavior; Female; GABA Modul

2019
Schizophrenia presenting with Koro-like symptoms.
    The Journal of neuropsychiatry and clinical neurosciences, 2013,Winter, Volume: 25, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Brain; Diazepam; Electroencephalo

2013
Peripubertal diazepam administration prevents the emergence of dopamine system hyperresponsivity in the MAM developmental disruption model of schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:10

    Topics: Amphetamine; Animals; Anxiety; Central Nervous System Sensitization; Diazepam; Dopaminergic Neurons;

2013
Prior antipsychotic drug treatment prevents response to novel antipsychotic agent in the methylazoxymethanol acetate model of schizophrenia.
    Schizophrenia bulletin, 2014, Volume: 40, Issue:2

    Topics: Allosteric Regulation; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Diazepam; Disea

2014
Amygdala Hyperactivity in MAM Model of Schizophrenia is Normalized by Peripubertal Diazepam Administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:10

    Topics: Action Potentials; Administration, Oral; Amygdala; Animals; Animals, Newborn; Anti-Anxiety Agents; A

2016
Loss of Parvalbumin in the Hippocampus of MAM Schizophrenia Model Rats Is Attenuated by Peripubertal Diazepam.
    The international journal of neuropsychopharmacology, 2016, Volume: 19, Issue:11

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Diazepam; Disease Models, Animal; Down-Regulation;

2016
Obsessive-compulsive disorder in UK clozapine-treated schizophrenia and schizoaffective disorder: a cause for clinical concern.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:1

    Topics: Adult; Antipsychotic Agents; Clozapine; Cohort Studies; Cross-Sectional Studies; Diazepam; Dose-Resp

2009
The safety and efficacy of benzodiazepine-modified treatments as a special form of unmodified ECT.
    The journal of ECT, 2010, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Benzodiazepines; Child; Depressive Disorder; Diazepam; Electroconvulsive Therapy;

2010
Diazepam discontinuation through agomelatine in schizophrenia with insomnia and depression.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:6

    Topics: Acetamides; Adult; Anti-Anxiety Agents; Depression; Diazepam; Humans; Hypnotics and Sedatives; Male;

2010
Further characterization of the predictive validity of the Brattleboro rat model for antipsychotic efficacy.
    Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:6

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Diazepam; Disease Models, Animal; Female; Imipramine;

2011
Polypharmacy in the treatment of schizophrenic patients in three University Centers in the Federation of Bosnia and Herzegovina (F/BH).
    Psychiatria Danubina, 2011, Volume: 23, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antiparkinson Agents; Antipsycho

2011
A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:9

    Topics: Allosteric Regulation; Amphetamine; Animals; Benzodiazepines; Diazepam; Disease Models, Animal; Dopa

2011
Local-global processing in early-onset schizophrenia: evidence for an impairment in shifting the spatial scale of attention.
    Brain and cognition, 2003, Volume: 51, Issue:1

    Topics: Adolescent; Affect; Antipsychotic Agents; Attention; Benzodiazepines; Clopenthixol; Diazepam; Female

2003
Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy.
    Psychiatry and clinical neurosciences, 2003, Volume: 57, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Diazepam; Diben

2003
An analysis of the efficacy of diazepam.
    Journal of neuropsychiatry, 1962, Volume: 3(Suppl 1)

    Topics: Chlordiazepoxide; Depression; Depressive Disorder; Diazepam; Schizophrenia; Tranquilizing Agents

1962
[CLINICAL EXPERIENCES WITH THE LIBRIUM ANALOGUE RO 5-2807 (VALIUM) IN PSYCHOTIC STATES].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1963, Volume: 92

    Topics: Bipolar Disorder; Chlordiazepoxide; Diazepam; Humans; Intellectual Disability; Mental Disorders; Par

1963
[THE ADVANCES OF MODERN PHARMACOTHERAPY OF THE ENDOGENOUS PSYCHOSES AND ITS SIGNIFICANCE FOR INSTITUTIONAL PSYCHIATRY].
    Wiener Zeitschrift fur Nervenheilkunde und deren Grenzgebiete, 1963, Volume: 21

    Topics: Chlordiazepoxide; Chlorprothixene; Diazepam; Humans; Phenothiazines; Psychiatry; Psychotic Disorders

1963
DIAZEPAM IN NEWLY ADMITTED SCHIZOPHRENICS.
    Diseases of the nervous system, 1963, Volume: 24

    Topics: Depression; Diazepam; Paranoid Disorders; Schizophrenia; Toxicology; Tranquilizing Agents

1963
DIAZEPAM: ITS ROLE IN A PRISON SETTING.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Adolescent; Diazepam; Epilepsy; Geriatrics; Humans; Mental Disorders; Prisons; Psychotic Disorders;

1964
COMPARISON OF DIAZEPAM, CHLORPROTHIXENE AND CHLORPROMAZINE IN CHRONIC SCHIZOPHRENIC PATIENTS.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Alcoholism; Brain; Brain Damage, Chronic; Chlorpromazine; Chlorprothixene; Diazepam; Schizophrenia;

1964
NOTES FROM THE LOG-BOOK OF A PSYCHOPHARMACOLOGICAL RESEARCH UNIT. II.
    Canadian Psychiatric Association journal, 1964, Volume: 9

    Topics: Antidepressive Agents; Books; Dextroamphetamine; Diazepam; Geriatrics; Humans; Mental Disorders; Met

1964
[OBSERVATIONS ON THE USE OF PHENYLPYRROLIDINOPENTANE AS AN ANTIASTHENIC AGENT IN TREATMENT WITH PSYCHOPHARMACOLOGICAL DRUGS].
    Gazzetta medica italiana, 1964, Volume: 123

    Topics: Amitriptyline; Anxiety; Anxiety Disorders; Asthenia; Bipolar Disorder; Chemical and Drug Induced Liv

1964
[CLINICAL TRIAL OF A NEW TRANQUILIZER, A BENZODIAZEPINE SERIES DERIVATIVE: RO 5-2807].
    Acta neurologica et psychiatrica Belgica, 1964, Volume: 64

    Topics: Anxiety; Anxiety Disorders; Autonomic Nervous System Diseases; Benzodiazepines; Combat Disorders; De

1964
[CLINICAL EXPERIENCES WITH VALIUM ROCHE, A NEW BENZODIAZEPINE DERIVATIVE].
    Schweizerische medizinische Wochenschrift, 1964, Mar-21, Volume: 94

    Topics: Antisocial Personality Disorder; Anxiety; Anxiety Disorders; Autonomic Nervous System Diseases; Benz

1964
DIAZEPAM THERAPY OF DEPRESSED PATIENTS.
    Journal of neuropsychiatry, 1964, Volume: 5

    Topics: Bipolar Disorder; Chlordiazepoxide; Depression; Depressive Disorder; Depressive Disorder, Major; Dia

1964
DIAZEPAM AS AN ADJUVANT IN PSYCHOTHERAPY.
    The American journal of psychiatry, 1964, Volume: 121

    Topics: Adolescent; Anxiety; Bipolar Disorder; Depression; Depressive Disorder, Major; Diazepam; Drug Therap

1964
AN INTERESTING OBSERVATION IN THE TREATMENT OF CHRONIC PSYCHIATRIC PATIENTS.
    The American journal of psychiatry, 1964, Volume: 121

    Topics: Biomedical Research; Diazepam; Drug Therapy; Patients; Schizophrenia; Schizophrenia, Childhood

1964
Comparisons of psychotropic drug prescribing patterns in acute psychiatric wards across Europe.
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:1

    Topics: Adult; Benzodiazepines; Biperiden; Chlorpromazine; Clozapine; Cyclohexanols; Diazepam; Drug Administ

2004
Ketamine-induced changes in rat behaviour: a possible animal model of schizophrenia. Test of predictive validity.
    Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:8

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Behavior

2004
A schizophrenia-related sensorimotor deficit links alpha 3-containing GABAA receptors to a dopamine hyperfunction.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Nov-22, Volume: 102, Issue:47

    Topics: Amphetamine; Animals; Anti-Anxiety Agents; Diazepam; Disease Models, Animal; Dopamine; Electrophysio

2005
Pharmacological management of akathisia in combination with psychological interventions by a mental health nurse consultant.
    Journal of psychiatric and mental health nursing, 2006, Volume: 13, Issue:1

    Topics: Akathisia, Drug-Induced; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Diazepam; Drug

2006
BDNF Val66Met polymorphism and GAD67 mRNA expression in the prefrontal cortex of subjects with schizophrenia.
    The American journal of psychiatry, 2006, Volume: 163, Issue:3

    Topics: Brain-Derived Neurotrophic Factor; Cohort Studies; Diazepam; Female; gamma-Aminobutyric Acid; Gene E

2006
Neuroleptic malignant syndrome induced by ziprasidone on the second day of treatment.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2007, Volume: 8, Issue:1

    Topics: Adult; Antipsychotic Agents; Biperiden; Diagnosis, Differential; Diazepam; Drug Therapy, Combination

2007
Treatment with haloperidol and diazepam alters GABA(A) receptor density in the rat brain.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Feb-15, Volume: 32, Issue:2

    Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Binding Sites; Brain; Diazepam; Dis

2008
Rapid neuroleptization reconsidered.
    The American journal of psychiatry, 1980, Volume: 137, Issue:1

    Topics: Acute Disease; Antipsychotic Agents; Diazepam; Humans; Psychotic Disorders; Schizophrenia

1980
Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia.
    Neuroscience letters, 1980, Volume: 20, Issue:3

    Topics: Adult; Antipsychotic Agents; Diazepam; Female; Glutamates; Humans; Male; Middle Aged; Schizophrenia

1980
Diazepam-induced changes in tardive dyskinesia: suggestions for a new conceptual model.
    Biological psychiatry, 1982, Volume: 17, Issue:6

    Topics: Adult; Aged; Antipsychotic Agents; Diazepam; Dose-Response Relationship, Drug; Dyskinesia, Drug-Indu

1982
The use of a diazepam test for the study of depressive state structure and for choice of therapy.
    Biological psychiatry, 1982, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Bipolar Disorder;

1982
High doses of diazepam improve neuroleptic-resistant chronic schizophrenic patients.
    Psychopharmacology, 1983, Volume: 81, Issue:1

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Diazepam; Drug Resistance; Female; Humans; Male; Middl

1983
The effect of neuroleptic treatment and of high dosage diazepam therapy on beta-endorphin immunoreactivity in plasma of schizophrenic patients.
    Journal of neural transmission, 1984, Volume: 59, Issue:2

    Topics: Adolescent; Adult; Antipsychotic Agents; beta-Endorphin; Diazepam; Dose-Response Relationship, Drug;

1984
Is there a correlation between the concentration of beta-carbolines and their pharmacodynamic effects?
    Progress in clinical and biological research, 1982, Volume: 90

    Topics: Alkaloids; Animals; Benzodiazepines; Blood Platelets; Carbolines; Diazepam; Female; Harmine; Humans;

1982
High dose diazepam treatment and its effect on prolactin secretion in adolescent schizophrenic patients.
    Psychopharmacology, 1984, Volume: 82, Issue:4

    Topics: Adolescent; Diazepam; Female; Humans; Male; Prolactin; Schizophrenia

1984
Case report: psychomotor status-like episodes under haloperidol treatment.
    The British journal of psychiatry : the journal of mental science, 1984, Volume: 145

    Topics: Adult; Diazepam; Epilepsy; Haloperidol; Humans; Male; Schizophrenia

1984
High dose diazepam in schizophrenia.
    Psychopharmacology, 1980, Volume: 71, Issue:1

    Topics: Adult; Anxiety; Diazepam; Female; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Sle

1980
[Psychopharmacologic approach to studying various problems in slowly progressive schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:1

    Topics: Depressive Disorder; Diagnosis, Differential; Diazepam; Dibenzothiepins; Dothiepin; Humans; Methotri

1982
Neuroendocrine study of the mechanism of action of electroconvulsive therapy.
    Neuropsychobiology, 1982, Volume: 8, Issue:3

    Topics: Adult; Diazepam; Dopamine beta-Hydroxylase; Electroconvulsive Therapy; Female; Humans; Hydrocortison

1982
Antipsychotic effect of cannabidiol.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:10

    Topics: Adult; Cannabidiol; Diazepam; Drug Therapy, Combination; Female; Haloperidol; Humans; Psychiatric St

1995
Auditory hallucinations suppressed by etizolam in a patient with schizophrenia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1993, Volume: 38, Issue:8

    Topics: Adult; Antipsychotic Agents; Auditory Perception; Diazepam; Drug Therapy, Combination; Female; Hallu

1993
[Benzodiazepine monotherapy in acute schizophrenia].
    Der Nervenarzt, 1994, Volume: 65, Issue:1

    Topics: Acute Disease; Adult; Anti-Anxiety Agents; Diazepam; Humans; Lorazepam; Male; Schizophrenia; Schizop

1994
Do benzodiazepines modify the incidence of neuroleptic-induced dystonia?
    The American journal of psychiatry, 1993, Volume: 150, Issue:3

    Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diazepam; Dystonia; Humans; Schizophrenia

1993
Behavioral approaches to polydipsia.
    Biological psychiatry, 1993, Aug-01, Volume: 34, Issue:3

    Topics: Adult; Behavior Therapy; Combined Modality Therapy; Diazepam; Female; Flurazepam; Humans; Male; Rein

1993
Benzodiazepine receptor distribution and diazepam binding in schizophrenia: an exploratory study.
    Psychiatry research, 1997, Feb-07, Volume: 68, Issue:2-3

    Topics: Adult; Benzodiazepines; Binding Sites; Chronic Disease; Diazepam; Flumazenil; Frontal Lobe; Growth H

1997
Diazepam-responsive neuroleptic malignant syndrome: a diagnostic subtype?
    The American journal of psychiatry, 1997, Volume: 154, Issue:6

    Topics: Antipsychotic Agents; Catatonia; Diazepam; Female; Humans; Infusions, Intravenous; Middle Aged; Neur

1997
[Decompensated "anorexia" at age 52--diagnosis of schizophrenia 30 years later].
    Psychiatrische Praxis, 1999, Volume: 26, Issue:2

    Topics: Adult; Anorexia; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Female; Haloperidol; Humans; M

1999
Risperidone treatment of tardive dyskinesia and dystonia.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:5

    Topics: Antipsychotic Agents; Diazepam; Dopamine Antagonists; Drug Administration Schedule; Drug Therapy, Co

1999
Changes in heart rate during administration of local anesthetics in neuropsychiatric patients.
    Journal of oral surgery (American Dental Association : 1965), 1979, Volume: 37, Issue:5

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anti-Anxiety Agents; Autonomic Nervous System; Diazepa

1979
Letter: Are benzodiazepines antipsychotic agents?
    Lancet (London, England), 1975, Nov-01, Volume: 2, Issue:7940

    Topics: Diazepam; Humans; Schizophrenia

1975
Letter: Are benzodiazepines antipsychotic agents?
    Lancet (London, England), 1975, Nov-22, Volume: 2, Issue:7943

    Topics: Diazepam; Drug Evaluation; Humans; Schizophrenia

1975
Relationships between clinical and biochemical effects of melperone and thiothixene in psychotic women.
    Archiv fur Psychiatrie und Nervenkrankheiten, 1979, Volume: 227, Issue:3

    Topics: Butyrophenones; Diazepam; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydrox

1979
Smooth-pursuit eye movements in schizophrenia: recent findings.
    Research publications - Association for Research in Nervous and Mental Disease, 1975, Volume: 54

    Topics: Adult; Attention; Chlorpromazine; Depression; Diagnosis, Differential; Diazepam; Electronystagmograp

1975
Editorial: Tranquillizers causing aggression.
    British medical journal, 1975, Jan-18, Volume: 1, Issue:5950

    Topics: Aggression; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Group Processes; Haplorhini; H

1975
The biphasic effect of gradually increased doses of diazepam on prolactin secretion in acute schizophrenic patients.
    The Israel annals of psychiatry and related disciplines, 1979, Volume: 17, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Diazepam; Female; Humans; Male; Prolactin; Schizophrenia

1979
Drug-induced EEG changes studied on two-dimensional rectangular coordinates using principal component analysis.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1979, Volume: 12, Issue:1

    Topics: Adult; Amitriptyline; Chlorpromazine; Computers; Diazepam; Electroencephalography; Haloperidol; Huma

1979
Benzodiazepines in chronic schizophrenia.
    Biological psychiatry, 1979, Volume: 14, Issue:3

    Topics: Adult; Diazepam; Double-Blind Method; Drug Therapy, Combination; Female; Haloperidol; Humans; Male;

1979
[Pathogenesis of stereotyped behavior].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:9

    Topics: Animals; Behavior; Caudate Nucleus; Diazepam; Disease Models, Animal; gamma-Aminobutyric Acid; Halop

1979
Complex partial seizures simulating schizophrenia .
    JAMA, 1977, Mar-28, Volume: 237, Issue:13

    Topics: Adult; Chlorpromazine; Diagnosis, Differential; Diagnostic Errors; Diazepam; Electroencephalography;

1977
Pavor nocturnus in a schizophrenic patient: a review and case study.
    The American journal of psychiatry, 1978, Volume: 135, Issue:2

    Topics: Adult; Chlorpromazine; Diazepam; Dreams; Humans; Male; Schizophrenia; Schizophrenic Psychology; Stre

1978
Psychopharmacology for psychiatric and psychiatric-organic diseases.
    Comprehensive therapy, 1978, Volume: 4, Issue:5

    Topics: Antidepressive Agents, Tricyclic; Anxiety; Depression; Diazepam; Dose-Response Relationship, Drug; D

1978
A possible subgroup of the schizophrenic syndrome and implications for treatment.
    American journal of psychotherapy, 1976, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Diazepam; Dominance, Cerebral; Dys

1976
Diazepam in the treatment of tardive dyskinesia. Preliminary observations.
    International pharmacopsychiatry, 1976, Volume: 11, Issue:4

    Topics: Adult; Chlorpromazine; Diazepam; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Schizo

1976
NMS complicated by diazepam.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 160

    Topics: Aged; Coma; Diazepam; Haloperidol; Humans; Male; Neuroleptic Malignant Syndrome; Risk Factors; Schiz

1992
[Diagnostic and therapeutic aspects of neuroleptic malignant syndrome based on 12 cases].
    Wiener klinische Wochenschrift, 1991, Volume: 103, Issue:1

    Topics: Adult; Amantadine; Antipsychotic Agents; Bromocriptine; Dantrolene; Depressive Disorder; Diazepam; D

1991
Possible enhancing effects of diazepam with reserpine in a chronic schizophrenic patient with tardive dyskinesia.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:4

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Diazepam; Drug Therapy, Combination; Dyskinesia, Drug-

1989
Parkinsonism induced by high doses of diazepam.
    Biological psychiatry, 1985, Volume: 20, Issue:4

    Topics: Adult; Antipsychotic Agents; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Male; Middl

1985
[Intensive psychopharmacologic therapy of slowly-progressive schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1985, Volume: 85, Issue:1

    Topics: Adult; Antipsychotic Agents; Chlordiazepoxide; Diazepam; Female; Fluphenazine; Humans; Infusions, Pa

1985
[Psychotropic drug therapy using maintenance dosage pumps].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1987, Volume: 87, Issue:6

    Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Diazepam; Dibenzazepines; Female; Humans; Infusi

1987
Successful propranolol therapy for neuroleptic-induced akathisia resistant to anticholinergic and benzodiazepine drugs.
    Clinical neuropharmacology, 1988, Volume: 11, Issue:4

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Diazepam; Female; Humans; Male; Propranolol; P

1988
[Use of the dexamethasone test in the differential diagnosis of depressive states].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:4

    Topics: 11-Hydroxycorticosteroids; Adolescent; Adult; Aged; Anxiety; Bipolar Disorder; Depression; Depressiv

1986
Schneiderian first-rank symptoms caused by benzodiazepine withdrawal.
    The British journal of psychiatry : the journal of mental science, 1986, Volume: 148

    Topics: Adult; Benzodiazepines; Diazepam; Female; Hallucinations; Humans; Middle Aged; Schizophrenia; Substa

1986
Diazepam in a patient with chronic schizophrenia complicated by agoraphobia.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:1

    Topics: Adult; Agoraphobia; Behavior Therapy; Combined Modality Therapy; Diazepam; Humans; Male; Phobic Diso

1987
Liquid-chromatographic assay of diazepam and its major metabolites in serum, and application to pharmacokinetic study of high doses of diazepam in schizophrenics.
    Clinical chemistry, 1985, Volume: 31, Issue:10

    Topics: Administration, Oral; Chromatography, High Pressure Liquid; Diazepam; Female; Humans; Kinetics; Nord

1985
Drug induced dystonia tarda: treatment with L-dopa.
    Diseases of the nervous system, 1973, Volume: 34, Issue:3

    Topics: Antipsychotic Agents; Chlorpromazine; Chronic Disease; Diazepam; Dihydroxyphenylalanine; Dystonia Mu

1973
[Results of glucose tolerance tests and changes in inorganic serum phosphate and potassium levels in schizophrenic patients responding to treatment with psychotropic drugs].
    International pharmacopsychiatry, 1971, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Amitriptyline; Chlorpromazine; Diazepam; Glucose Tolerance Test; Haloperidol; Hum

1971
Niacin and the schizophrenic patient.
    The American journal of psychiatry, 1970, Volume: 127, Issue:4

    Topics: Diazepam; Edema; Gastrointestinal Diseases; Humans; Liver Function Tests; Mental Disorders; Niacinam

1970
[Neurological analysis of the action of tranquilizing agents--benzodiazepine derivatives].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:5

    Topics: Antisocial Personality Disorder; Benzazepines; Chlordiazepoxide; Diazepam; Humans; Hypertension; Men

1972
Paradoxical effects of phenothiazines.
    The Psychiatric quarterly, 1968, Volume: 42, Issue:1

    Topics: Adult; Amitriptyline; Chlorpromazine; Diazepam; Female; Humans; Meclofenoxate; Meprobamate; Phenothi

1968
Electroencephalographic analysis of atropine coma.
    Acta physiologica Academiae Scientiarum Hungaricae, 1972, Volume: 41, Issue:1

    Topics: Atropine; Barbiturates; Bipolar Disorder; Coma; Delirium; Diazepam; Electroencephalography; Epilepsy

1972
Lorazepam in the treatment of severe anxiety and anxiety associated with psychotic conditions.
    Current medical research and opinion, 1973, Volume: 1, Issue:5

    Topics: Adult; Aggression; Amitriptyline; Anxiety Disorders; Ataxia; Benzodiazepinones; Bipolar Disorder; Ch

1973
The care of psychotic patients.
    American family physician, 1974, Volume: 9, Issue:1

    Topics: Adult; Affective Symptoms; Ambulatory Care; Anxiety; Bipolar Disorder; Brain Damage, Chronic; Diazep

1974
Influence of neuroleptics and benzodiazepines on metabolism of tricyclic antidepressants in man.
    The American journal of psychiatry, 1974, Volume: 131, Issue:8

    Topics: Animals; Antidepressive Agents; Carbon Radioisotopes; Chlordiazepoxide; Diazepam; Dose-Response Rela

1974
Age-sex differences in response to antidepressant drugs.
    The Journal of nervous and mental disease, 1974, Volume: 159, Issue:2

    Topics: Adjustment Disorders; Adolescent; Adult; Age Factors; Aged; Antidepressive Agents; Anxiety; Chlorpro

1974
[Drawings of a schizophrenic during a Sakel cure].
    Annales medico-psychologiques, 1967, Volume: 125, Issue:2

    Topics: Adult; Chlorpromazine; Convulsive Therapy; Diazepam; Haloperidol; Humans; Male; Methotrimeprazine; P

1967
Intravenous diazepam in drug-induced dystonic reactions.
    The British journal of psychiatry : the journal of mental science, 1972, Volume: 121, Issue:560

    Topics: Adult; Bipolar Disorder; Butyrophenones; Diazepam; Female; Humans; Injections, Intravenous; Male; Mi

1972
[Clinical and therapeutic aspects of cyclothymic depressions of late onset].
    Psychiatria clinica, 1971, Volume: 4, Issue:5

    Topics: Age Factors; Amitriptyline; Delusions; Depression; Diagnosis, Differential; Diazepam; Humans; Middle

1971
[On the use of sulpiride in psychiatric therapy].
    Annales medico-psychologiques, 1969, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aged; Amitriptyline; Butyrophenones; Diazepam; Drug Synergism; Female; Humans; Ma

1969
[Parenteral treatment of depressive diseases].
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Oct-10, Volume: 44, Issue:40

    Topics: Antidepressive Agents; Bipolar Disorder; Dementia; Depression; Depressive Disorder, Major; Desiprami

1970
The present status of psychotropic drugs.
    The Practitioner, 1970, Volume: 205, Issue:227

    Topics: Antidepressive Agents; Chlormethiazole; Diazepam; Dibenzazepines; Fluphenazine; Haloperidol; Humans;

1970
Treatment of psychic masochism in schizophrenic patients.
    Diseases of the nervous system, 1970, Volume: 31

    Topics: Adolescent; Adult; Amitriptyline; Behavior Therapy; Chlordiazepoxide; Diazepam; Female; Haloperidol;

1970
[The basic criteria for clinical evaluation of the effect of tranquilizers].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:12

    Topics: Benactyzine; Bipolar Disorder; Central Nervous System Diseases; Chlordiazepoxide; Diazepam; Epilepsy

1970
[Comparison of the characteristics of the effect of tranquilizing agents under experimental and clinical conditions].
    Farmakologiia i toksikologiia, 1971, Volume: 34, Issue:1

    Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Diseases; Chlordiazepoxide; Depre

1971
[Management of psychotic drive disorders].
    Wiener medizinische Wochenschrift (1946), 1968, Sep-07, Volume: 118, Issue:36

    Topics: Adult; Bipolar Disorder; Chlorprothixene; Diazepam; Drive; Female; Fluphenazine; Humans; Imipramine;

1968
[Use of diazepam in psychiatric practice].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1968, Volume: 68, Issue:8

    Topics: Adult; Aged; Antisocial Personality Disorder; Chlordiazepoxide; Diazepam; Female; Humans; Male; Ment

1968
[Medazepam. A new tranquilizer: simple test, intraindividual comparisons and combination therapy].
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:12

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Benzazepines; Chlordiazepoxide; Depression; Diazepam

1968
"Valium" in the treatment of schizophrenia.
    The Medical journal of Australia, 1969, Jun-28, Volume: 1, Issue:26

    Topics: Auditory Perception; Diazepam; Hallucinations; Humans; Schizophrenia

1969
[Management of chronic schizophrenias using Valium].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1969, Volume: 104, Issue:1

    Topics: Aged; Catatonia; Chronic Disease; Diazepam; Drug Synergism; Female; Humans; Paranoid Disorders; Schi

1969
Extrinsic factors influencing responses to psychotherapeutic drugs.
    Archives of general psychiatry, 1969, Volume: 21, Issue:1

    Topics: Adult; Amitriptyline; Analysis of Variance; Black or African American; Chlorpromazine; Depression; D

1969
[Valium--a hypno-tranquilizer].
    Psychiatria et neurologia, 1966, Volume: 151, Issue:5

    Topics: Diazepam; Humans; Schizophrenia

1966