diazepam and Reperfusion Injury
diazepam has been researched along with Reperfusion Injury in 4 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"The protective effect and mechanism of diazepam on ischemia neurons during cerebral ischemia and reperfusion were studied." | 7.71 | Effect of diazepam on the contents of amino acids and free radical during ischemia/reperfusion injury. ( Hu, B; Mei, Y; Qiu, X; Sun, S; Tong, E; Wei, G, 2001) |
"The results show that repeated administration of diazepam (5 mg/kg for 5 days) reduced the cardiac performance in reperfusion, and significantly exacerbated the ischemia-reperfusion injury." | 3.75 | The effect of repeated diazepam administration on myocardial function in the ischemia-reperfused isolated rat heart. ( Godini, A; Kayhani, B; Pourshanazari, A; Reshadat, S; Shackebaei, D, 2009) |
"The protective effect and mechanism of diazepam on ischemia neurons during cerebral ischemia and reperfusion were studied." | 3.71 | Effect of diazepam on the contents of amino acids and free radical during ischemia/reperfusion injury. ( Hu, B; Mei, Y; Qiu, X; Sun, S; Tong, E; Wei, G, 2001) |
"Mannitol flux was greater in ischemic tissues than in reperfused tissues." | 1.37 | In vitro and in vivo responses of mucosa from the large colon of horses to ischemia and reperfusion. ( Freeman, DE; Graham, AS; Grosche, A; Morton, AJ; Polyak, MM, 2011) |
"Reperfusion hyperalgesia manifested as a decrease in tail flick latency, following tail immersion in 49 degrees C water, after the release of the tourniquet." | 1.29 | Attenuation of reperfusion hyperalgesia in the rat by systemic administration of benzodiazepines. ( Cartmell, SM; Mitchell, D, 1993) |
Research
Studies (4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Shackebaei, D | 1 |
Kayhani, B | 1 |
Godini, A | 1 |
Pourshanazari, A | 1 |
Reshadat, S | 1 |
Graham, AS | 1 |
Grosche, A | 1 |
Morton, AJ | 1 |
Polyak, MM | 1 |
Freeman, DE | 1 |
Cartmell, SM | 1 |
Mitchell, D | 1 |
Hu, B | 1 |
Mei, Y | 1 |
Wei, G | 1 |
Qiu, X | 1 |
Sun, S | 1 |
Tong, E | 1 |
Other Studies
4 other studies available for diazepam and Reperfusion Injury
Article | Year |
---|---|
The effect of repeated diazepam administration on myocardial function in the ischemia-reperfused isolated rat heart.
Topics: Animals; Diazepam; Heart; In Vitro Techniques; Male; Rats; Rats, Wistar; Reperfusion Injury | 2009 |
In vitro and in vivo responses of mucosa from the large colon of horses to ischemia and reperfusion.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Colon; Diazepam; Electric Impedance; Horse | 2011 |
Attenuation of reperfusion hyperalgesia in the rat by systemic administration of benzodiazepines.
Topics: Animals; Behavior, Animal; Benzodiazepines; Chlordiazepoxide; Depression, Chemical; Diazepam; Dose-R | 1993 |
Effect of diazepam on the contents of amino acids and free radical during ischemia/reperfusion injury.
Topics: Amino Acids; Animals; Brain Ischemia; Diazepam; Free Radicals; GABA Modulators; Male; Rats; Rats, Wi | 2001 |