diazepam has been researched along with Renal Insufficiency in 2 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While some case reports indicate that high doses of propylene glycol (PG) may result in metabolic acidosis, there has been no large-scale study that evaluated the risk of metabolic acidosis in patients receiving PG-containing benzodiazepines for acute alcohol withdrawal." | 3.88 | Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model. ( Bodreau, C; Elbarbry, F; Farthing, K; Jahn, A, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jahn, A | 1 |
| Bodreau, C | 1 |
| Farthing, K | 1 |
| Elbarbry, F | 1 |
| Nagumo, K | 1 |
| Tanaka, M | 2 |
| Chuang, VT | 1 |
| Setoyama, H | 1 |
| Watanabe, H | 1 |
| Yamada, N | 1 |
| Kubota, K | 1 |
| Matsushita, K | 1 |
| Yoshida, A | 1 |
| Jinnouchi, H | 1 |
| Anraku, M | 1 |
| Kadowaki, D | 1 |
| Ishima, Y | 1 |
| Sasaki, Y | 1 |
| Otagiri, M | 1 |
| Maruyama, T | 1 |
2 other studies available for diazepam and Renal Insufficiency
| Article | Year |
|---|---|
Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model.
Topics: Acid-Base Equilibrium; Acidosis; Alcoholism; Benzodiazepines; Diazepam; Female; Humans; Injections, | 2018 |
Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic diseases.
Topics: Aged; Amino Acids, Branched-Chain; Bilirubin; Biomarkers; Chronic Disease; Cysteine; Diabetes Mellit | 2014 |