diazepam and Psychoses, Alcoholic studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Psychoses, Alcoholic: A group of mental disorders associated with organic brain damage and caused by poisoning from alcohol.

Research Excerpts

Excerpt	Relevance	Reference
"Barbital was given by the oral route, diazepam as intramuscular injections."	2.64	Delirium tremens: a double-blind comparison of diazepam and barbital treatment. ( Kramp, P; Rafaelsen, OJ, 1978)
"Diazepam-treated patients became calm in one half the time needed to calm patients with paraldehyde."	2.64	Diazepam and paraldehyde for treatment of severe delirium tremens. A controlled trial. ( Johnson, AD; Maddrey, WL; Thompson, WL, 1975)
"Definitions of Delirium Tremens (DT) and related clinical states are discussed together with the concepts of aetiology and pathogenesis in relation to psychiatric disease."	2.36	Delirium tremens and related clinical states. Aetiology, pathophysiology and treatment. ( Hemmingsen, R; Kramp, P; Rafaelsen, OJ, 1979)
"A 34-yr-old male in delirium tremens required a total of 2640 mg iv diazepam for adequate sedation."	1.27	Unprecedented sedative requirements during delirium tremens. ( Natow, A; Nolop, KB, 1985)

Timeframe	Studies, this research(%)	All Research%
pre-1990	53 (96.36)	18.7374
1990's	1 (1.82)	18.2507
2000's	1 (1.82)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
POELDINGER, W	1
HARDER, A	1
Kirpichenko, AA	1
Danilenko, AM	1
Veselovskiĭ, VV	1
Kuznetsov, VI	1
Vorobeĭchik, GN	1
Tuz, MV	1
Adams, MA	1
Hirst, M	1
Landers, DF	1
Pristach, CA	1
Smith, CM	1
Whitney, RB	1
Wartenberg, AA	1
Metz, G	1
Nebel, B	1
Millman, RB	1
Boucek, J	1
Aaronson, LM	1
Hinman, DJ	1
Okamoto, M	1
Gouffier, E	2
Monterio, I	1
Schnurman, D	1
Voiry, AM	2
Monteiro, I	1
Schnurmann, D	1
Wasilewski, D	1
Matsumoto, H	1
Kur, E	1
Dziklińska, A	1
Woźny, E	1
Stencka, K	1
Skalski, M	1
Chaba, P	1
Szelenberger, W	1
Hemmingsen, R	1
Kramp, P	3
Rafaelsen, OJ	2
Rønsted, P	1
Hansen, T	1
Thompson, WL	2
Beckmann, H	1
Athen, D	1
Salum, I	1
Johnson, AD	1
Maddrey, WL	1
Gray, LW	1
Ruddy, MC	1
van Sweden, B	1
Grässler, W	1
Foy, A	1
March, S	1
Drinkwater, V	1
Crabbe, JC	1
Young, ER	1
Tam, B	1
Kosobud, A	1
Belknap, JK	1
Laursen, SE	1
Dittmar, G	1
Lincke, HO	1
Mitchell, TR	1
Nolop, KB	1
Natow, A	1
Aufderheide, TP	1
Frascone, RJ	1
Cicero, JJ	1
Favazza, AR	1
Martin, P	1
Defer, B	1
Billiard-Grasser, K	1
Fiack, R	1
Oge, V	1
Capoun, V	1
Kafka, J	1
Helmus, C	1
Spahn, JG	1
Novotný, V	1
Kolibás, E	1
Junasová, D	1
Kallwellis, G	1
Angst, J	1
Fracchia, J	1
Sheppard, C	1
Merlis, S	1
Brown, JH	1
Moggey, DE	1
Shane, FH	1
Brune, F	1
Busch, H	1
Rawson, RA	1
Lipscomb, WR	1
Rozynko, J	1
Helmchen, H	1
Iandolo, C	1
Aleksandrovskiĭ, IuA	1
Warot, P	1
Arnott, G	1
Petit, H	1
Hubschmann, B	1
Toselli, E	1
Pommé, B	1
Planche, R	1
Coudert, AJ	1
Hoagland, RJ	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464]			Phase 4	142 participants (Anticipated)	Interventional	2020-07-06	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Delirium tremens and related clinical states. Aetiology, pathophysiology and treatment. Acta psychiatrica Scandinavica, 1979, Volume: 59, Issue:4 Topics: Adrenal Insufficiency; Alcohol Withdrawal Delirium; Animals; Antipsychotic Agents; Avitaminosis; Bar	1979
[Therapy in alcoholic delirium]. Deutsche medizinische Wochenschrift (1946), 1987, Dec-11, Volume: 112, Issue:50 Topics: Alcohol Withdrawal Delirium; Carbamazepine; Chlormethiazole; Diazepam; Haloperidol; Humans; Phenytoi	1987
[Recent developments in psychopharmacology]. Praxis, 1968, Feb-06, Volume: 57, Issue:5 Topics: Antidepressive Agents; Barbiturates; Bipolar Disorder; Chlormethiazole; Depression; Diazepam; Electr	1968

Article	Year
Delirium tremens: a double-blind comparison of diazepam and barbital treatment. Acta psychiatrica Scandinavica, 1978, Volume: 58, Issue:2 Topics: Administration, Oral; Adult; Age Factors; Alcohol Withdrawal Delirium; Barbital; Barbiturates; Clini	1978
Barbital and diazepam plasma levels during treatment of delirium tremens. Acta psychiatrica Scandinavica, 1979, Volume: 59, Issue:3 Topics: Alcohol Withdrawal Delirium; Barbital; Barbiturates; Clinical Trials as Topic; Diazepam; Double-Blin	1979
Diazepam and paraldehyde for treatment of severe delirium tremens. A controlled trial. Annals of internal medicine, 1975, Volume: 82, Issue:2 Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Clinical Trials as Topic; Diazepam; Female; Hepatiti	1975
Treatment of alcohol withdrawal syndromes. The Medical letter on drugs and therapeutics, 1971, Mar-05, Volume: 13, Issue:5 Topics: Chloral Hydrate; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Drug Synergism; Ethanol; Huma	1971
Combination medications in psychiatric treatment: patterns in a group of elderly hospital patients. Journal of the American Geriatrics Society, 1971, Volume: 19, Issue:4 Topics: Age Factors; Aged; Amitriptyline; Antidepressive Agents; Antihypertensive Agents; Antisocial Persona	1971

diazepam and Psychoses, Alcoholic

Research Excerpts

Research

Studies (55)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Article	Year
[CLINICAL EXPERIENCES WITH THE LIBRIUM ANALOGUE RO 5-2807 (VALIUM) IN PSYCHOTIC STATES]. Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1963, Volume: 92 Topics: Bipolar Disorder; Chlordiazepoxide; Diazepam; Humans; Intellectual Disability; Mental Disorders; Par	1963
[TRIALS WITH RO 5-2807 IN ALCOHOLICS (98 CASES)]. Annales medico-psychologiques, 1964, Volume: 122 Topics: Alcoholic Intoxication; Alcoholics; Alcoholism; Diazepam; Humans; Mental Disorders; Psychoses, Alcoh	1964
[CLINICAL EXPERIENCES WITH VALIUM ROCHE, A NEW BENZODIAZEPINE DERIVATIVE]. Schweizerische medizinische Wochenschrift, 1964, Mar-21, Volume: 94 Topics: Antisocial Personality Disorder; Anxiety; Anxiety Disorders; Autonomic Nervous System Diseases; Benz	1964
[Some peculiarities of clinical signs and treatment of alcoholic psychosis in women]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2006, Volume: 106, Issue:3 Topics: Acute Disease; Adult; Age Factors; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Drug Therapy	2006
[Prolonged pharmacologic sleep in the complex treatment of patients with severe forms of alcoholic delirium]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:7 Topics: Adult; Alcohol Withdrawal Delirium; Antipsychotic Agents; Barbiturates; Diazepam; Droperidol; Drug T	1981
The ethanol withdrawal syndrome in the rat: effects of drug treatment on adrenal gland and urinary catecholamines. Substance and alcohol actions/misuse, 1982, Volume: 3, Issue:5 Topics: Adrenal Glands; Alcohol Withdrawal Delirium; Animals; Catecholamines; Clonidine; Dexamethasone; Diaz	1982
Alcohol withdrawal syndrome. American family physician, 1983, Volume: 27, Issue:5 Topics: Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Humans; Psychoses, Alc	1983
Alcohol withdrawal syndromes - prediction from detailed medical and drinking histories. Drug and alcohol dependence, 1983, Volume: 11, Issue:2 Topics: Adult; Aged; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Female; Flurazepam	1983
Treatment of alcohol withdrawal syndrome. JAMA, 1983, Sep-09, Volume: 250, Issue:10 Topics: Alcohol Withdrawal Delirium; Chlordiazepoxide; Diazepam; Humans; Injections; Psychoses, Alcoholic	1983
[Clonidine in severe alcohol withdrawal delirium]. Fortschritte der Medizin, 1983, Jul-14, Volume: 101, Issue:26 Topics: Alcohol Withdrawal Delirium; Chlormethiazole; Clonidine; Diazepam; Haloperidol; Humans; Monitoring,	1983
Treatment of delirium tremens. Hospital & community psychiatry, 1982, Volume: 33, Issue:5 Topics: Alcohol Withdrawal Delirium; Chlordiazepoxide; Diazepam; Humans; Psychoses, Alcoholic	1982
[Our experience with treatment of delirium tremens]. Ceskoslovenska psychiatrie, 1982, Volume: 78, Issue:5 Topics: Adult; Alcohol Withdrawal Delirium; Chlormethiazole; Chlorprothixene; Diazepam; Female; Humans; Male	1982
Effects of diazepam on ethanol withdrawal. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:2 Topics: Alcohol Withdrawal Delirium; Animals; Behavior, Animal; Cats; Diazepam; Dose-Response Relationship,	1982
[Treatment of delirium tremens by means of intravenous administration of large doses of diazepam]. La Nouvelle presse medicale, 1980, Oct-11, Volume: 9, Issue:37 Topics: Alcohol Withdrawal Delirium; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Injections,	1980
[Treatment of alcohol withdrawal syndromes with intravenous administration of high dosage diazepam]. Medecine & chirurgie digestives, 1980, Volume: 9, Issue:4 Topics: Alcohol Withdrawal Delirium; Diazepam; Female; Humans; Injections, Intravenous; Male; Psychoses, Alc	1980
Assessment of diazepam loading dose therapy of delirium tremens. Alcohol and alcoholism (Oxford, Oxfordshire), 1996, Volume: 31, Issue:3 Topics: Adult; Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Diazepam; Dose-Response Relationship, Drug;	1996
Management of alcohol withdrawal syndromes. Archives of internal medicine, 1978, Volume: 138, Issue:2 Topics: Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relationship, Dru	1978
[Therapy of delirium tremens]. Deutsche medizinische Wochenschrift (1946), 1978, Sep-15, Volume: 103, Issue:37 Topics: Alcohol Withdrawal Delirium; Chlordiazepoxide; Chlormethiazole; Diazepam; Haloperidol; Humans; Inten	1978
Treatment of delirium tremens. The British journal of addiction to alcohol and other drugs, 1975, Volume: 70 Suppl 1 Topics: Alcohol Withdrawal Delirium; Chlormethiazole; Diazepam; Humans; Psychoses, Alcoholic	1975
Letter: Diazepam or paraldehyde for delirium tremens. Annals of internal medicine, 1975, Volume: 82, Issue:6 Topics: Alcohol Withdrawal Delirium; Diazepam; Humans; Paraldehyde; Psychoses, Alcoholic	1975
Letter: Diazepam or paraldehyde for delirium tremens. Annals of internal medicine, 1975, Volume: 83, Issue:2 Topics: Alcohol Withdrawal Delirium; Diazepam; Humans; Paraldehyde; Psychoses, Alcoholic	1975
Diazepam loading for alcohol withdrawal: seizure risk in epileptics. Biological psychiatry, 1989, Volume: 26, Issue:8 Topics: Administration, Oral; Adult; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relati	1989
[The pre-delirium syndrome in alcoholic patients in ambulatory care and its treatment]. Psychiatrie, Neurologie, und medizinische Psychologie, 1989, Volume: 41, Issue:2 Topics: Adolescent; Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Chlormethiazole; Combined Modality	1989
Use of an objective clinical scale in the assessment and management of alcohol withdrawal in a large general hospital. Alcoholism, clinical and experimental research, 1988, Volume: 12, Issue:3 Topics: Adult; Aged; Alcohol Withdrawal Delirium; Diazepam; Ethanol; Female; Hospitals, General; Humans; Mal	1988
Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1 Topics: Alcohol Withdrawal Delirium; Alcohols; Animals; Anticonvulsants; Diazepam; Disease Susceptibility; E	1986
Alcohol withdrawal. Journal of the Tennessee Medical Association, 1988, Volume: 81, Issue:2 Topics: Alcohol Withdrawal Delirium; Chlordiazepoxide; Diazepam; Humans; Male; Middle Aged; Psychoses, Alcoh	1988
Unprecedented sedative requirements during delirium tremens. Critical care medicine, 1985, Volume: 13, Issue:4 Topics: Adult; Alcohol Withdrawal Delirium; Diazepam; Dose-Response Relationship, Drug; Drug Administration	1985
Simultaneous bilateral anterior and posterior shoulder dislocations. The American journal of emergency medicine, 1985, Volume: 3, Issue:4 Topics: Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Humans; Male; Middle Aged; Psychoses, Alcoholic;	1985
Chemotherapy of delirium tremens: a survey of physicians' preferences. The American journal of psychiatry, 1974, Volume: 131, Issue:9 Topics: Alcohol Withdrawal Delirium; Antipsychotic Agents; Attitude of Health Personnel; Barbiturates; Chlor	1974
[Clinical use of clorazepate, especially in treatment of acute alcoholic psychoses]. Annales medico-psychologiques, 1968, Volume: 2, Issue:5 Topics: Adult; Aged; Benzazepines; Diazepam; Drug Synergism; Humans; Male; Meprobamate; Middle Aged; Pregnan	1968
Drug therapy in alcoholism. It is especially important in the prevention of such complications as seizures, DT's, Wernicke's encephalopathy, or polyneuritis. IMJ. Illinois medical journal, 1971, Volume: 139, Issue:6 Topics: Alcoholism; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Diazepam; Disulfiram; Humans; Hydroxy	1971
Centrophenoxine and chlormethiazol in the treatment of delirium tremens. Activitas nervosa superior, 1972, Volume: 14, Issue:2 Topics: Acetates; Central Nervous System Stimulants; Chlormethiazole; Diazepam; Evaluation Studies as Topic;	1972
Delirium tremens in head and neck surgery. The Laryngoscope, 1974, Volume: 84, Issue:9 Topics: Aged; Alcohol Withdrawal Delirium; Chlordiazepoxide; Diazepam; Humans; Laryngeal Neoplasms; Male; Mi	1974
Our experience with the treatment of delirium tremens with diazepam. Activitas nervosa superior, 1974, Volume: 16, Issue:3 Topics: Adult; Aged; Alcohol Withdrawal Delirium; Chlordiazepoxide; Diazepam; Humans; Hypnotics and Sedative	1974
[Cerebral convulsions as early signs of delirium tremens]. Zeitschrift fur arztliche Fortbildung, 1972, Aug-15, Volume: 66, Issue:16 Topics: Adult; Chloral Hydrate; Chlormethiazole; Diazepam; Electroencephalography; Female; Humans; Male; Mid	1972
Chlorpromazine contraindicated in delirium tremens. The American journal of psychiatry, 1973, Volume: 130, Issue:9 Topics: Chlordiazepoxide; Chlorpromazine; Cholestasis; Diazepam; Humans; Psychoses, Alcoholic; Seizures	1973
Delirium tremens: a comparison of intravenous treatment with diazepam and chlordiazepoxide. Scottish medical journal, 1972, Volume: 17, Issue:1 Topics: Adult; Anticonvulsants; Chlordiazepoxide; Diazepam; Female; Follow-Up Studies; Humans; Injections, I	1972
Anticonvulsive-sedative treatment of delirium alcoholicum. Quarterly journal of studies on alcohol, 1971, Volume: 32, Issue:2 Topics: Adult; Carbamazepine; Chlordiazepoxide; Chlormethiazole; Diazepam; Dibenzazepines; Drug Synergism; F	1971
Acute delirium in amitriptyline-perphenazine therapy of alcoholism. Clinical toxicology, 1971, Volume: 4, Issue:1 Topics: Acute Disease; Adult; Alcoholism; Amitriptyline; Delirium; Diazepam; Drug Combinations; Hallucinatio	1971
[Psychopharmacological agents in treatment of psychiatric emergencies]. La Clinica terapeutica, 1971, Mar-31, Volume: 56, Issue:6 Topics: Adult; Age Factors; Aged; Antidepressive Agents; Dementia; Diazepam; Haloperidol; Humans; Hypnotics	1971
An intensive one-year study of delirium tremens in Copenhagen from August 1, 1961, to July 31, 1962. Acta psychiatrica Scandinavica. Supplementum, 1965, Volume: 187 Topics: Adult; Aged; Barbiturates; Blood; Blood Glucose; Bromides; Chlorpromazine; Clinical Enzyme Tests; Co	1965
[Modern therapy of alcoholism]. Il Policlinico. Sezione pratica, 1970, Jan-05, Volume: 77, Issue:1 Topics: Alcoholism; Chlordiazepoxide; Coma; Diazepam; Fructose; Humans; Hypotension; Psychoses, Alcoholic; S	1970
[The basic criteria for clinical evaluation of the effect of tranquilizers]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:12 Topics: Benactyzine; Bipolar Disorder; Central Nervous System Diseases; Chlordiazepoxide; Diazepam; Epilepsy	1970
[Alcoholic confusional oneiric states and their treatment]. Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1968, Volume: 13, Issue:10 Topics: Adult; Age Factors; Diazepam; Family Characteristics; Humans; Middle Aged; Psychoses, Alcoholic	1968
[Preliminary observations on the use of Valium in intravenous injections in delirium tremens]. Minerva medica, 1969, Jun-23, Volume: 60, Issue:50 Topics: Adult; Diazepam; Humans; Injections, Intravenous; Male; Middle Aged; Psychoses, Alcoholic	1969
[Apropos of the effect of injectable valium in 60 cases of delirium tremens]. Annales medico-psychologiques, 1965, Volume: 123, Issue:2 Topics: Diazepam; Humans; Male; Middle Aged; Psychoses, Alcoholic	1965
Treatment of delirium tremens. Southern medical journal, 1966, Volume: 59, Issue:9 Topics: Chlorpromazine; Diazepam; Folic Acid; Humans; Psychoses, Alcoholic; Thiamine; Tranquilizing Agents;	1966