diazepam has been researched along with Prostatic Neoplasms, Castration-Resistant in 1 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Prostatic Neoplasms, Castration-Resistant: Tumors or cancer of the PROSTATE which can grow in the presence of low or residual amount of androgen hormones such as TESTOSTERONE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study evaluated the safety profile and recommended phase II dosing of apatorsen in patients with advanced cancer." | 2.82 | A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers. ( Bazov, J; Chi, KN; Gleave, ME; Higano, CS; Hotte, SJ; Jacobs, C; Kollmannsberger, C; Mukherjee, SD; Stewart, PS; Yu, EY, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chi, KN | 1 |
| Yu, EY | 1 |
| Jacobs, C | 1 |
| Bazov, J | 1 |
| Kollmannsberger, C | 1 |
| Higano, CS | 1 |
| Mukherjee, SD | 1 |
| Gleave, ME | 1 |
| Stewart, PS | 1 |
| Hotte, SJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 1 Study Evaluating A Second Generation Antisense Oligonucleotide (OGX 427) That Inhibits Heat Shock Protein 27 (Hsp27[NCT00487786] | Phase 1 | 64 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for diazepam and Prostatic Neoplasms, Castration-Resistant
| Article | Year |
|---|---|
A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers.
Topics: Adult; Aged; Aged, 80 and over; Diazepam; Dose-Response Relationship, Drug; Drug-Related Side Effect | 2016 |