diazepam has been researched along with Porphyria, Acute Intermittent in 3 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Porphyria, Acute Intermittent: An autosomal dominant porphyria that is due to a deficiency of HYDROXYMETHYLBILANE SYNTHASE in the LIVER, the third enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features are recurrent and life-threatening neurologic disturbances, ABDOMINAL PAIN, and elevated level of AMINOLEVULINIC ACID and PORPHOBILINOGEN in the urine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The patient was initially treated for her abdominal pain and vomiting." | 1.35 | Drug use in porphyria: a therapeutic dilemma. ( Jimmy, B; Jose, J; Saravu, K; Shastry, BA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jose, J | 1 |
| Saravu, K | 1 |
| Shastry, BA | 1 |
| Jimmy, B | 1 |
| Tishler, PV | 1 |
| Stiefelhagen, P | 1 |
3 other studies available for diazepam and Porphyria, Acute Intermittent
| Article | Year |
|---|---|
Drug use in porphyria: a therapeutic dilemma.
Topics: Abdominal Pain; Adult; Amines; Anticonvulsants; Antiemetics; Antihypertensive Agents; Chest Pain; Cy | 2008 |
The effect of therapeutic drugs and other pharmacologic agents on activity of porphobilinogen deaminase, the enzyme that is deficient in intermittent acute porphyria.
Topics: Animals; Chlorpromazine; Diazepam; Enzyme Activation; Erythrocytes; Humans; Hydroxymethylbilane Synt | 1999 |
[Abdominal pain after taking drug tablets. Acute intermittent porphyria].
Topics: Abdomen, Acute; Adult; Diagnosis, Differential; Diazepam; Female; Humans; Hypnotics and Sedatives; P | 2000 |