diazepam has been researched along with Neurodegenerative Diseases in 5 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Riluzole is an antiglutamatergic agent and the only drug to offer some effect on the life expectancy of ALS patients." | 5.46 | Excitatory-inhibitory imbalance in the brain of the wobbler mouse model of amyotrophic lateral sclerosis substantiated by riluzole and diazepam. ( Andreasen, SR; Christensen, TB; Holm, MM; Lundbye, CJ; Schmitt-John, T; Thielsen, KD, 2017) |
| "Riluzole is an antiglutamatergic agent and the only drug to offer some effect on the life expectancy of ALS patients." | 1.46 | Excitatory-inhibitory imbalance in the brain of the wobbler mouse model of amyotrophic lateral sclerosis substantiated by riluzole and diazepam. ( Andreasen, SR; Christensen, TB; Holm, MM; Lundbye, CJ; Schmitt-John, T; Thielsen, KD, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scarf, AM | 1 |
| Ittner, LM | 1 |
| Kassiou, M | 1 |
| Supasai, S | 1 |
| González, EA | 1 |
| Rowland, DJ | 1 |
| Hobson, B | 1 |
| Bruun, DA | 1 |
| Guignet, MA | 1 |
| Soares, S | 1 |
| Singh, V | 1 |
| Wulff, H | 1 |
| Saito, N | 1 |
| Harvey, DJ | 1 |
| Lein, PJ | 1 |
| Wu, T | 1 |
| Ido, K | 1 |
| Osada, Y | 1 |
| Kotani, S | 1 |
| Tamaoka, A | 1 |
| Hanada, T | 1 |
| Andreasen, SR | 1 |
| Lundbye, CJ | 1 |
| Christensen, TB | 1 |
| Thielsen, KD | 1 |
| Schmitt-John, T | 1 |
| Holm, MM | 1 |
| Fredriksson, A | 1 |
| Pontén, E | 1 |
| Gordh, T | 1 |
| Eriksson, P | 1 |
1 review available for diazepam and Neurodegenerative Diseases
| Article | Year |
|---|---|
The translocator protein (18 kDa): central nervous system disease and drug design.
Topics: Acetamides; Apoptosis; Central Nervous System; Central Nervous System Diseases; Drug Design; Humans; | 2009 |
4 other studies available for diazepam and Neurodegenerative Diseases
| Article | Year |
|---|---|
Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate.
Topics: Animals; Brain Diseases; Cholinesterase Inhibitors; Diazepam; GABA Modulators; Gliosis; Isoflurophat | 2020 |
The neuroprotective effect of perampanel in lithium-pilocarpine rat seizure model.
Topics: Animals; Anticonvulsants; Antigens, Nuclear; Brain; Cell Death; Diazepam; Dose-Response Relationship | 2017 |
Excitatory-inhibitory imbalance in the brain of the wobbler mouse model of amyotrophic lateral sclerosis substantiated by riluzole and diazepam.
Topics: Amyotrophic Lateral Sclerosis; Animals; Diazepam; Disease Models, Animal; Hippocampus; Mice, Inbred | 2017 |
Neonatal exposure to a combination of N-methyl-D-aspartate and gamma-aminobutyric acid type A receptor anesthetic agents potentiates apoptotic neurodegeneration and persistent behavioral deficits.
Topics: Analgesics; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Animals, Newborn; Anti-Anxiety | 2007 |