Page last updated: 2024-10-25

diazepam and Neuralgia

diazepam has been researched along with Neuralgia in 11 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"Neuropathic pain is commonly associated with affective disorders such as anxiety and depression."5.35Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain. ( Blackbeard, J; Pheby, T; Rice, AS; Segerdahl, AR; Wallace, VC, 2008)
"The effects of diazepam or Ro5-4864 on neuropathic pain were completely blocked by pretreatment with a neurosteroid synthesis inhibitor, aminoglutethimide (AMG)."1.43Inhibition of Neuropathic Pain by a Single Intraperitoneal Injection of Diazepam in the Rat: Possible Role of Neurosteroids. ( Chen, SL; Liu, XG; Wei, XH; Zang, Y; Zheng, WH, 2016)
"Neuropathic pain is a serious chronic disorder caused by lesion or dysfunction in the nervous systems."1.36Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de ( Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K, 2010)
"Neuropathic pain is commonly associated with affective disorders such as anxiety and depression."1.35Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain. ( Blackbeard, J; Pheby, T; Rice, AS; Segerdahl, AR; Wallace, VC, 2008)
"Clomipramine used alone is an affective analgesic against organic pain due to a lesion of the peripheral nervous system, in particular post-herpetic pain."1.26[The treatment of organic pain of the peripheral nervous system using clomipramine. 30 cases (author's transl)]. ( Castaigne, P; Laplane, D; Morales, R, 1979)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Hayashi, S1
Nakata, E1
Morita, A1
Mizuno, K1
Yamamura, K1
Kato, A1
Ohashi, K1
Jaiswal, S1
Uniyal, A1
Tiwari, V1
Raja Ayyannan, S1
Chen, SL1
Zang, Y1
Zheng, WH1
Wei, XH1
Liu, XG1
Munro, G1
Lopez-Garcia, JA1
Rivera-Arconada, I1
Erichsen, HK1
Nielsen, EØ1
Larsen, JS1
Ahring, PK1
Mirza, NR1
Wallace, VC1
Segerdahl, AR1
Blackbeard, J1
Pheby, T1
Rice, AS1
Witschi, R1
Punnakkal, P1
Paul, J1
Walczak, JS1
Cervero, F1
Fritschy, JM1
Kuner, R1
Keist, R1
Rudolph, U1
Zeilhofer, HU1
Castaigne, P1
Laplane, D1
Morales, R1
Borello, ED1
Vago Muiños, HA1
Tyler, HR1
Meyer, JS1
Binns, PM1
Ericsson, AD1
Vulpe, M1
Mertens, HG1
Lützenkirchen, H1

Reviews

1 review available for diazepam and Neuralgia

ArticleYear
Advances in neurology.
    The Practitioner, 1968, Volume: 201, Issue:204

    Topics: Analgesics; Anticoagulants; Brain; Brain Neoplasms; Carbamazepine; Cerebrovascular Disorders; Contra

1968

Other Studies

10 other studies available for diazepam and Neuralgia

ArticleYear
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes,

2010
Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones.
    Bioorganic & medicinal chemistry, 2022, 04-15, Volume: 60

    Topics: Amidohydrolases; Analgesics; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Monoacylglycer

2022
Inhibition of Neuropathic Pain by a Single Intraperitoneal Injection of Diazepam in the Rat: Possible Role of Neurosteroids.
    The Chinese journal of physiology, 2016, 02-29, Volume: 59, Issue:1

    Topics: Animals; Benzodiazepinones; Carrier Proteins; Diazepam; Flumazenil; Injections, Intraperitoneal; Int

2016
Comparison of the novel subtype-selective GABAA receptor-positive allosteric modulator NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with diazepam, zolpidem, bretazenil, and gaboxadol in rat models of inflammatory
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:3

    Topics: Allosteric Regulation; Animals; Benzimidazoles; Benzodiazepinones; Diazepam; GABA Modulators; Humans

2008
Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain.
    Neuroscience letters, 2008, Dec-19, Volume: 448, Issue:1

    Topics: Amines; Analgesics; Animal Diseases; Animals; Anxiety; Behavior, Animal; Cyclohexanecarboxylic Acids

2008
Presynaptic alpha2-GABAA receptors in primary afferent depolarization and spinal pain control.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jun-01, Volume: 31, Issue:22

    Topics: Animals; Diazepam; Gene Expression Regulation; Hyperalgesia; Injections, Spinal; Membrane Potentials

2011
[The treatment of organic pain of the peripheral nervous system using clomipramine. 30 cases (author's transl)].
    La Nouvelle presse medicale, 1979, Mar-10, Volume: 8, Issue:11

    Topics: Adult; Aged; Clomipramine; Diazepam; Dibenzazepines; Drug Evaluation; Female; Fludrocortisone; Herpe

1979
[Glossopharyngeal neuralgia. A case of this rare condition treated successfully wtih 5-carbamoil diazepine].
    Anales espanoles de odontoestomatologia, 1974, Volume: 33, Issue:3

    Topics: Carbamates; Diazepam; Glossopharyngeal Nerve; Humans; Neuralgia

1974
Sphenopalatine gangionectomy for cluster headache.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1970, Volume: 92, Issue:5

    Topics: Adult; Analgesics; Caffeine; Carbamazepine; Cortisone; Diazepam; Ergotamine; Female; Ganglia, Autono

1970
[Neuropsychotropic drugs in the treatment of so-called pain syndromes].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Aminobutyrates; Benperidol; Chronic Disease; Diazepam; Humans; Hydantoins; Neuralgia; Pain; Procaina

1970