diazepam has been researched along with Nephrotic Syndrome in 4 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of chronic renal disease on the serum free fraction of phenytoin, diazepam and propranolol was examined in vitro among 60 conservatively treated patients with renal insufficiency of varying degree and different etiology, and in 10 patients with a nephrotic syndrome." | 3.67 | Serum protein binding of phenytoin, diazepam and propranolol in chronic renal diseases. ( Neuvonen, PJ; Tallgren, LG; Tiula, E, 1987) |
| "The plasma protein binding of diazepam and lidocaine was measured in patients with renal disease (those with uremia, nephrotic syndrome, or who had received a transplant) and in age- and sex- matched control subjects." | 3.66 | Diazepam and lidocaine plasma protein binding in renal disease. ( Davis, D; Grossman, SH; Kitchell, BB; Routledge, PA; Shand, DG, 1982) |
| " As a consequence, shorter dosing intervals of these drugs seems to be advisable, rather than a reduction in the total daily dose." | 2.35 | Drug protein binding and the nephrotic syndrome. ( Azarnoff, DL; Gugler, R, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ergün, I | 1 |
| Akbostanci, MC | 1 |
| Canbakan, B | 1 |
| Koçer, B | 1 |
| Ensari, A | 1 |
| Nergizoglu, G | 1 |
| Keven, K | 1 |
| Grossman, SH | 1 |
| Davis, D | 1 |
| Kitchell, BB | 1 |
| Shand, DG | 1 |
| Routledge, PA | 1 |
| Gugler, R | 1 |
| Azarnoff, DL | 1 |
| Tiula, E | 1 |
| Tallgren, LG | 1 |
| Neuvonen, PJ | 1 |
1 review available for diazepam and Nephrotic Syndrome
| Article | Year |
|---|---|
Drug protein binding and the nephrotic syndrome.
Topics: Antipyrine; Blood Proteins; Clofibrate; Diazepam; Half-Life; Humans; Kinetics; Nephrotic Syndrome; P | 1976 |
3 other studies available for diazepam and Nephrotic Syndrome
| Article | Year |
|---|---|
Minimal change nephrotic syndrome with stiff-person syndrome: is there a link?
Topics: Adult; Cyclophosphamide; Diazepam; Drug Therapy, Combination; Electromyography; Humans; Immunity, Ce | 2005 |
Diazepam and lidocaine plasma protein binding in renal disease.
Topics: Adult; Aged; Blood Proteins; Diazepam; Fatty Acids, Nonesterified; Female; Humans; Kidney Diseases; | 1982 |
Serum protein binding of phenytoin, diazepam and propranolol in chronic renal diseases.
Topics: Creatinine; Diazepam; Humans; Kidney Failure, Chronic; Nephrotic Syndrome; Orosomucoid; Phenytoin; P | 1987 |