diazepam has been researched along with Necrosis in 21 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was undertaken to determine whether diazepam, a potent, centrally penetrating GABAmimetic, alone or in combination with insulin, could mitigate postischemic seizures or regional selective neuronal necrosis and infarction." | 7.68 | Postischemic seizures and necrotizing ischemic brain damage: neuroprotective effect of postischemic diazepam and insulin. ( Auer, RN; Voll, CL, 1991) |
| "Acute fulminant hepatic necrosis was associated with repeated oral administration of diazepam (1." | 3.69 | Fulminant hepatic failure associated with oral administration of diazepam in 11 cats. ( Bank, S; Brunt, JE; Center, SA; Dring, LA; Elston, TH; House, J; Levy, JK; Lynch, LR; Reitz, BL; Rodan, I; Rosen, DK; Rowland, PH, 1996) |
| " The present study was undertaken to determine whether diazepam, a potent, centrally penetrating GABAmimetic, alone or in combination with insulin, could mitigate postischemic seizures or regional selective neuronal necrosis and infarction." | 3.68 | Postischemic seizures and necrotizing ischemic brain damage: neuroprotective effect of postischemic diazepam and insulin. ( Auer, RN; Voll, CL, 1991) |
| "The significant occurrence of thrombophlebitis in patients administered diazepam intravenously was described recently." | 3.66 | Poloxamer 188 as vehicle for injectable diazepam. ( Bernardoni, RJ; Ecanow, B; Prancan, AV; Sadove, MS, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (66.67) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, L | 1 |
| Zhou, Y | 1 |
| Wang, Y | 1 |
| Ohno, S | 1 |
| Kobayashi, K | 1 |
| Uchida, S | 1 |
| Amano, O | 1 |
| Sakagami, H | 1 |
| Nagasaka, H | 1 |
| Ukley, B | 1 |
| Hermann, W | 1 |
| Ratcliffe, HL | 2 |
| Snyder, RL | 1 |
| Mikhaĭlenko, AA | 1 |
| Beliakov, VA | 1 |
| Sinitsyn, LN | 1 |
| Kolpashchikova, IF | 1 |
| Shidlovskiĭ, AS | 1 |
| Prancan, AV | 1 |
| Ecanow, B | 1 |
| Bernardoni, RJ | 1 |
| Sadove, MS | 1 |
| Center, SA | 1 |
| Elston, TH | 1 |
| Rowland, PH | 1 |
| Rosen, DK | 1 |
| Reitz, BL | 1 |
| Brunt, JE | 1 |
| Rodan, I | 1 |
| House, J | 1 |
| Bank, S | 1 |
| Lynch, LR | 1 |
| Dring, LA | 1 |
| Levy, JK | 1 |
| Joist, A | 1 |
| Tibesku, CO | 1 |
| Neuber, M | 1 |
| Frerichmann, U | 1 |
| Joosten, U | 1 |
| Varma, AJ | 1 |
| Fisher, BK | 1 |
| Sarin, MK | 1 |
| Steiness, E | 2 |
| Rasmussen, F | 2 |
| Svendsen, O | 2 |
| Nielsen, P | 1 |
| Ben-Ari, Y | 1 |
| Lagowska, Y | 1 |
| Le Gal La Salle, G | 1 |
| Tremblay, E | 1 |
| Ottersen, OP | 1 |
| Naquet, R | 1 |
| Larsen, JP | 1 |
| Tassinari, CA | 1 |
| Roger, J | 1 |
| Dravat, C | 1 |
| Gustaut, H | 1 |
| Voll, CL | 1 |
| Auer, RN | 1 |
| Hayward, IJ | 1 |
| Wall, HG | 1 |
| Jaax, NK | 1 |
| Wade, JV | 1 |
| Marlow, DD | 1 |
| Nold, JB | 1 |
| Williams, R | 1 |
| Grivaux, M | 1 |
| Soulié, J | 1 |
| Diallo, A | 1 |
| Renard, C | 1 |
| Chevalley, J | 1 |
| Guaitani, A | 1 |
| Marcucci, F | 1 |
| Garattini, S | 1 |
| Detweiler, DK | 1 |
| Luginbühl, H | 1 |
| Jorgensen, F | 1 |
| Ulff-Moller, B | 1 |
1 review available for diazepam and Necrosis
| Article | Year |
|---|---|
Problems of fulminant hepatic failure.
Topics: Acute Disease; Adrenal Cortex Hormones; Amylases; Brain Diseases; Brain Stem; Diazepam; Dihydroxyphe | 1972 |
20 other studies available for diazepam and Necrosis
| Article | Year |
|---|---|
Effect of mild hypothermia on glutamate receptor expression after status epilepticus.
Topics: Animals; Apoptosis; Blotting, Western; Cell Count; Diazepam; Electrodes, Implanted; Electroencephalo | 2012 |
Cytotoxicity and type of cell death induced by midazolam in human oral normal and tumor cells.
Topics: Anesthetics, Intravenous; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Diazepam; DNA Frag | 2012 |
[Subacute Parkinson's disease after suicide attempt with diazepam].
Topics: Adult; Antiparkinson Agents; Cerebellum; Diazepam; Disease Progression; Drug Overdose; Follow-Up Stu | 2013 |
Arteriosclerotic stenosis of the intramural coronary arteries of chickens: further evidence of a relation to social factors.
Topics: Animals; Arteriosclerosis; Behavior, Animal; Coronary Disease; Diazepam; Female; Male; Myocardium; N | 1967 |
[Use of sodium oxybutyrate and diazepam for removing the psychomotor excitation in hepatic coma].
Topics: Animals; Carbon Tetrachloride Poisoning; Cats; Diazepam; Drug Evaluation; Drug Evaluation, Preclinic | 1980 |
Poloxamer 188 as vehicle for injectable diazepam.
Topics: Animals; Diazepam; Injections; Male; Necrosis; Pharmaceutical Vehicles; Poloxalene; Polyethylene Gly | 1980 |
Fulminant hepatic failure associated with oral administration of diazepam in 11 cats.
Topics: Animals; Anti-Anxiety Agents; Cat Diseases; Cats; Diazepam; Female; Hepatic Encephalopathy; Liver; M | 1996 |
[Gangrene of the fingers caused by accidental intra-arterial injection of diazepam].
Topics: Amputation, Surgical; Angiography; Anti-Anxiety Agents; Arterial Occlusive Diseases; Diagnosis, Diff | 1999 |
Diazepam-induced coma with bullae and eccrine sweat gland necrosis.
Topics: Adult; Coma; Diazepam; Humans; Male; Necrosis; Skin Diseases, Vesiculobullous; Substance-Related Dis | 1977 |
A comparative study of serum creatine phosphokinase (CPK) activity in rabbits, pigs and humans after intramuscular injection of local damaging drugs.
Topics: Animals; Creatine Kinase; Diazepam; Digoxin; Female; Humans; Injections, Intramuscular; Lidocaine; M | 1978 |
Diazepam pretreatment reduces distant hippocampal damage induced by intra-amygdaloid injections of kainic acid.
Topics: Amygdala; Animals; Convulsants; Diazepam; Hippocampus; Injections; Kainic Acid; Male; Necrosis; Pyrr | 1978 |
[Necrosis of a finger after radial artery cannulation].
Topics: Adult; Aged; Arm; Arteries; Blood Coagulation Disorders; Catheterization; Diazepam; Fingers; Gangren | 1977 |
[Local necrosis following intramuscular injection].
Topics: Animals; Creatine Kinase; Diazepam; Humans; Injections, Intramuscular; Isotonic Solutions; Lidocaine | 1976 |
Letter: Comments on a startling article: "loss of limb following intravenous diazepam".
Topics: Amputation, Surgical; Arm; Benzodiazepines; Diazepam; Epilepsy; Humans; Injections, Intra-Arterial; | 1975 |
Postischemic seizures and necrotizing ischemic brain damage: neuroprotective effect of postischemic diazepam and insulin.
Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Diazepam; Insulin; Male; Necrosis; Nervous System; R | 1991 |
Decreased brain pathology in organophosphate-exposed rhesus monkeys following benzodiazepine therapy.
Topics: Animals; Brain; Diazepam; Macaca mulatta; Male; Midazolam; Necrosis; Neurons; Soman | 1990 |
[Therapeutic hyperosmolarity].
Topics: Adult; Bicarbonates; Blood Transfusion; Brain Diseases; Chemical and Drug Induced Liver Injury; Diaz | 1973 |
Increased aggression and toxicity in grouped male mice treated with tranquilizing benzodiazepines.
Topics: Aggression; Animals; Behavior, Animal; Diazepam; Dibenzazepines; Female; Humans; Male; Methylation; | 1971 |
The significance of naturally occurring coronary and cerebral arterial disease in animals.
Topics: Analysis of Variance; Animals; Animals, Zoo; Basal Ganglia; Brain; Carnivora; Cerebral Arterial Dise | 1968 |
[Abuse of hypnotics and sedatives by young addicts].
Topics: Adolescent; Adult; Barbiturates; Diazepam; Female; Humans; Hypnotics and Sedatives; Morphine; Necros | 1971 |