diazepam has been researched along with Muscular Diseases in 42 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effectiveness of diazepam pretreatment in preventing succinylcholine (SCh)-induced fasciculations and body pains, 587 patients were randomly allocated to six groups." | 7.67 | Diazepam does not prevent succinylcholine-induced fasciculations and myalgia. A comparative evaluation of the effect of diazepam and d-tubocurarine pretreatments. ( Manchikanti, L, 1984) |
| "To determine the effectiveness of diazepam pretreatment in preventing succinylcholine (SCh)-induced fasciculations and body pains, 587 patients were randomly allocated to six groups." | 3.67 | Diazepam does not prevent succinylcholine-induced fasciculations and myalgia. A comparative evaluation of the effect of diazepam and d-tubocurarine pretreatments. ( Manchikanti, L, 1984) |
| " This study explored the influence of organic cosolvent-induced myotoxicity on the bioavailability of a model compound, diazepam." | 1.28 | Effect of organic cosolvent-induced skeletal muscle damage on the bioavailability of intramuscular [14C]diazepam. ( Brazeau, GA; Fung, HL, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (95.24) | 18.7374 |
| 1990's | 1 (2.38) | 18.2507 |
| 2000's | 1 (2.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PAYNE, RW | 1 |
| SORENSON, EJ | 1 |
| SMALLEY, TK | 1 |
| BRANDT, EN | 1 |
| OLAFSON, RA | 1 |
| MULDER, DW | 1 |
| HOWARD, FM | 1 |
| CAZORT, RJ | 1 |
| Nielsen, AN | 1 |
| Mathiesen, C | 1 |
| Blackburn-Munro, G | 1 |
| Carter, CH | 1 |
| Little, SC | 1 |
| Johnson, BK | 1 |
| Anhalt, MA | 1 |
| Chastain, DE | 1 |
| Greenblatt, DJ | 1 |
| Shader, RI | 1 |
| Abernethy, DR | 1 |
| Kaeser, HE | 1 |
| Manchikanti, L | 1 |
| Davies, AO | 1 |
| Meinck, HM | 1 |
| Ricker, K | 2 |
| Conrad, B | 1 |
| Friedman, GD | 1 |
| Hauzeur, F | 1 |
| Zastrow, R | 1 |
| Kiwitt, A | 1 |
| Daras, M | 1 |
| Spiro, AJ | 1 |
| Kramm, HJ | 1 |
| Lisewski, G | 1 |
| Burke, DJ | 1 |
| Mattioli, A | 1 |
| Giordanengo, F | 1 |
| Lo Guercio, G | 1 |
| Prati, R | 1 |
| Marbach, JJ | 1 |
| Dworkin, SF | 1 |
| Rosenthal, RL | 1 |
| Brazeau, GA | 1 |
| Fung, HL | 1 |
| Nazareth, ID | 1 |
| King, MB | 1 |
| Owen-Falkenberg, A | 1 |
| Clinton, ME | 1 |
| Dettbarn, WD | 1 |
| Filip, V | 1 |
| Sladká, R | 1 |
| Jarosová, M | 1 |
| Libingerová, E | 1 |
| Bacíková, R | 1 |
| Tůma, I | 1 |
| Novotný, J | 1 |
| Haskovcová, V | 1 |
| Faltus, F | 1 |
| Karen, P | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Taylor, JF | 1 |
| Lapierre, YD | 1 |
| Elie, R | 1 |
| Tetreault, L | 1 |
| Sigwald, J | 3 |
| Guilleminault, C | 2 |
| Rondot, P | 1 |
| Raverdy, P | 1 |
| Singer, B | 1 |
| Wallis, WE | 1 |
| Van Poznak, A | 1 |
| Plum, F | 1 |
| Castaigne, P | 1 |
| Tenser, RB | 1 |
| Corbett, JJ | 1 |
| Tyler, HR | 1 |
| Korczyn, AD | 1 |
| Goldberg, GJ | 1 |
| Heitmann, R | 1 |
| Deraney, MF | 1 |
| Serre, H | 2 |
| Cadilhac, J | 2 |
| Simon, L | 2 |
| Minvielle, J | 2 |
| Sany, J | 2 |
| Mertens, HG | 1 |
| Daly, RJ | 1 |
| Kane, FJ | 1 |
| Sie, KL | 1 |
| Blom, PS | 1 |
| Goor, C | 1 |
4 reviews available for diazepam and Muscular Diseases
| Article | Year |
|---|---|
Drug therapy. Current status of benzodiazepines.
Topics: Alcoholic Beverages; Alcoholism; Anesthetics; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Bone Di | 1983 |
Drug-induced myasthenic syndromes.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Autoimmune Diseas | 1984 |
Baclofen: a preliminary report of its pharmacological properties and therapeutic efficacy in spasticity.
Topics: Adolescent; Adult; Aminobutyrates; Animals; Chlorobenzenes; Chronic Disease; Clinical Trials as Topi | 1974 |
Advances in neurology.
Topics: Analgesics; Anticoagulants; Brain; Brain Neoplasms; Carbamazepine; Cerebrovascular Disorders; Contra | 1968 |
3 trials available for diazepam and Muscular Diseases
| Article | Year |
|---|---|
Use of push-pull maximum weight scale for the measurement of tonic spasticity.
Topics: Diazepam; Humans; Muscular Diseases; Myography; Placebos | 1967 |
Baclofen: a preliminary report of its pharmacological properties and therapeutic efficacy in spasticity.
Topics: Adolescent; Adult; Aminobutyrates; Animals; Chlorobenzenes; Chronic Disease; Clinical Trials as Topi | 1974 |
Diazepam and benzoctamlne: effects on certain objective parameters of muscular spasticity.
Topics: Adult; Anthracenes; Clinical Trials as Topic; Diazepam; Electromyography; Female; Humans; Male; Ment | 1973 |
36 other studies available for diazepam and Muscular Diseases
| Article | Year |
|---|---|
DIAZEPAM, MEPROBAMATE, AND PLACEBO IN MUSCULOSKELETAL DISORDERS.
Topics: Biomedical Research; Bone Diseases; Chlordiazepoxide; Diazepam; Meprobamate; Muscular Diseases; Musc | 1964 |
"STIFF-MAN" SYNDROME: A REVIEW OF THE LITERATURE, REPORT OF THREE ADDITIONAL CASES AND DISCUSSION OF PATHOPHYSIOLOGY AND THERAPY.
Topics: Diazepam; Electromyography; Geriatrics; Humans; Male; Muscular Diseases; Pathology; Spasm; Tranquili | 1964 |
ROLE OF RELAXANTS IN TREATMENT OF TRAUMATIC MUSCULOSKELETAL DISORDERS: A DOUBLE-BLIND STUDY OF THREE AGENTS.
Topics: Anxiety; Anxiety Disorders; Biomedical Research; Carisoprodol; Chlormezanone; Diazepam; Double-Blind | 1964 |
Pharmacological characterisation of acid-induced muscle allodynia in rats.
Topics: Acids; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Carbazoles; Chr | 2004 |
The "stiff-man" syndrome. A report of two additional cases treated with diazepam.
Topics: Adult; Diazepam; Humans; Male; Middle Aged; Muscular Diseases; Spasm | 1967 |
Diazepam does not prevent succinylcholine-induced fasciculations and myalgia. A comparative evaluation of the effect of diazepam and d-tubocurarine pretreatments.
Topics: Anesthesia, General; Diazepam; Fasciculation; Humans; Muscular Diseases; Neurologic Manifestations; | 1984 |
Oral diazepam premedication reduces the incidence of post-succinylcholine muscle pains.
Topics: Adult; Diazepam; Double-Blind Method; Female; Humans; Male; Muscular Diseases; Nausea; Pain, Postope | 1983 |
The stiff-man syndrome: new pathophysiological aspects from abnormal exteroceptive reflexes and the response to clomipramine, clonidine, and tizanidine.
Topics: Adult; Brain Stem; Clomipramine; Clonidine; Diazepam; Electromyography; Female; Humans; Muscle Rigid | 1984 |
Phenylbutazone, musculoskeletal disease, and leukemia.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adult; Aged; Bone Diseases; Delivery of Health Care; Diazepa | 1982 |
[Differential diagnosis of increase in abdominal circumference: muscular abdominal bloating].
Topics: Abdomen; Adult; Ascites; Diagnosis, Differential; Diazepam; Female; Humans; Muscular Diseases | 1982 |
'Stiff-man syndrome' in an adolescent.
Topics: Adolescent; Age Factors; Child; Diagnosis, Differential; Diazepam; Electrodiagnosis; Humans; Male; M | 1981 |
[Contribution to the clinical picture abdominal muscular distension].
Topics: Abdominal Muscles; Abdominal Neoplasms; Adult; Diagnosis, Differential; Diazepam; Female; Humans; Mu | 1977 |
An approach to the treatment of spasticity.
Topics: Adrenergic alpha-Antagonists; Baclofen; Brain Diseases; Dantrolene; Diazepam; Humans; Mephenesin; Mu | 1975 |
[Intra-arterial administration of anesthetic drugs. Experimental research].
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Bradycardia; Diazepam; Dogs; Femoral Artery; Hy | 1977 |
Chronic MPD, group therapy and psychodynamics.
Topics: Attitude; Diazepam; Ethanol; Facial Muscles; Humans; Interpersonal Relations; Meprobamate; MMPI; Mus | 1975 |
Chronic myofascial pain-dysfunction syndrome with chest pain.
Topics: Adult; Diazepam; Facial Muscles; Female; Humans; Malocclusion; Masticatory Muscles; Muscular Disease | 1975 |
Effect of organic cosolvent-induced skeletal muscle damage on the bioavailability of intramuscular [14C]diazepam.
Topics: Animals; Biological Availability; Body Temperature; Chromatography, High Pressure Liquid; Creatine K | 1990 |
Prescribing of benzodiazepines by casualty officers.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Child; Diazepam; Drug Utilization; Emergency Medicine; | 1989 |
[Does diazepam prevent against suxamethonium-induced fasciculation and myalgia?].
Topics: Diazepam; Fasciculation; Humans; Muscular Diseases; Pain; Succinylcholine | 1987 |
Prevention of phospholine-induced myopathy with d-tubocurarine, atropine sulfate, diazepam, and creatine phosphate.
Topics: Animals; Atropine; Calcium; Diaphragm; Diazepam; Injections, Subcutaneous; Male; Muscles; Muscular D | 1987 |
[Reaction to the sudden withdrawal of diazepam in patients with anxiety neurosis].
Topics: Anxiety Disorders; Diazepam; Gastrointestinal Diseases; Humans; Muscular Diseases; Substance Withdra | 1986 |
Tranquillising drugs and dystonia.
Topics: Benperidol; Child; Diazepam; Female; Heart Defects, Congenital; Humans; Muscular Diseases; Postopera | 1969 |
[Syndromes of permanent contracture (stiff-man syndrome of Moersch and Woltman; Isaacs' syndrome of continual activity of the muscle fibers, other permanent contractures). Attempted classification and pathogenic interpretation. Discussion of the role of t
Topics: Carbamazepine; Contracture; Diazepam; Electromyography; Fibromyalgia; Hydantoins; Interneurons; Moto | 1971 |
[Stiff man syndrome. Clinical, electrologic and therapeutic details].
Topics: Curare; Diagnosis, Differential; Diazepam; Electromyography; Emotions; Fatigue; Female; Humans; Midd | 1968 |
Generalized muscular stiffness, fasciculations, and myokymia of peripheral nerve origin.
Topics: Adult; Basal Metabolism; Biopsy; Diazepam; Electromyography; Humans; Male; Muscular Diseases; Myoclo | 1970 |
Sleep studies and therepeutic trial with L-dopa in a case of Stiffman syndrome.
Topics: Benzodiazepinones; Chlorobenzenes; Diazepam; Dihydroxyphenylalanine; Electrocardiography; Electromyo | 1973 |
Diazepam as a muscle relaxant.
Topics: Administration, Oral; Diazepam; Humans; Hypnotics and Sedatives; Injections, Intravenous; Muscle Rel | 1973 |
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; F | 1974 |
Intravenous diazepam in drug-induced dystonic reactions.
Topics: Adult; Bipolar Disorder; Butyrophenones; Diazepam; Female; Humans; Injections, Intravenous; Male; Mi | 1972 |
[The stiff-man syndrome].
Topics: Action Potentials; Diazepam; Electromyography; Humans; Male; Middle Aged; Movement Disorders; Muscle | 1968 |
Diaphragmatic flutter.
Topics: Diaphragm; Diazepam; Female; Humans; Muscular Diseases | 1967 |
[The stiff man syndrome].
Topics: Diazepam; Electromyography; Female; Fibromyalgia; Humans; Middle Aged; Muscular Diseases; Pain; Tach | 1971 |
[The stiff man syndrome].
Topics: Adult; Contracture; Diazepam; Electromyography; Female; Fibromyalgia; Humans; Male; Middle Aged; Mus | 1971 |
[Overexcitability of the gamma-motor neurons in "stiff-man" syndrome].
Topics: Adult; Aminobutyrates; Diazepam; Electromyography; Female; Humans; Motor Neurons; Muscular Diseases; | 1968 |
Two severe reactions to benzodiazepine compounds.
Topics: Adult; Alcoholism; Ataxia; Chlordiazepoxide; Diazepam; Drug Synergism; Humans; Male; Middle Aged; Mu | 1965 |
[A case of stiff-man syndrome in a woman].
Topics: Diabetes Complications; Diazepam; Female; Humans; Middle Aged; Muscular Diseases; Spasm | 1966 |